메뉴 건너뛰기




Volumn 29, Issue 44, 2011, Pages 7688-7695

Subunit vaccine efficacy against Botulinum neurotoxin subtypes

Author keywords

Botulinum neurotoxin serotype A; Botulism; Subunit vaccine; Synaptic vesicles; Vaccination

Indexed keywords

BOTULINUM TOXIN A; IMMUNOGLOBULIN; SUBUNIT VACCINE;

EID: 80053597280     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2011.07.134     Document Type: Article
Times cited : (13)

References (57)
  • 1
    • 0020073392 scopus 로고
    • Bacterial toxins: a table of lethal amounts
    • Gill D.M. Bacterial toxins: a table of lethal amounts. Microbiol Rev 1982, 46(March (1)):86-94.
    • (1982) Microbiol Rev , vol.46 , Issue.MARCH 1 , pp. 86-94
    • Gill, D.M.1
  • 2
    • 0033520494 scopus 로고    scopus 로고
    • Sequence homology and structural analysis of the clostridial neurotoxins
    • Lacy D.B., Stevens R.C. Sequence homology and structural analysis of the clostridial neurotoxins. J Mol Biol 1999, 291(September (5)):1091-1104.
    • (1999) J Mol Biol , vol.291 , Issue.SEPTEMBER 5 , pp. 1091-1104
    • Lacy, D.B.1    Stevens, R.C.2
  • 3
    • 0033748727 scopus 로고    scopus 로고
    • Development of vaccines for prevention of botulism
    • Byrne M.P., Smith L.A. Development of vaccines for prevention of botulism. Biochimie 2000, 82(September-October (9-10)):955-966.
    • (2000) Biochimie , vol.82 , Issue.SEPTEMBER OCTOBER 910 , pp. 955-966
    • Byrne, M.P.1    Smith, L.A.2
  • 4
    • 33748769520 scopus 로고    scopus 로고
    • A structural perspective of the sequence variability within botulinum neurotoxin subtypes A1-A4
    • Arndt J.W., Jacobson M.J., Abola E.E., Forsyth C.M., Tepp W.H., Marks J.D., et al. A structural perspective of the sequence variability within botulinum neurotoxin subtypes A1-A4. J Mol Biol 2006, 362(September (4)):733-742.
    • (2006) J Mol Biol , vol.362 , Issue.SEPTEMBER 4 , pp. 733-742
    • Arndt, J.W.1    Jacobson, M.J.2    Abola, E.E.3    Forsyth, C.M.4    Tepp, W.H.5    Marks, J.D.6
  • 5
    • 43149084857 scopus 로고    scopus 로고
    • Assessment: botulinum neurotoxin in the treatment of autonomic disorders and pain (an evidence-based review): report of the therapeutics and technology assessment subcommittee of the American academy of neurology
    • Naumann M., So Y., Argoff C.E., Childers M.K., Dykstra D.D., Gronseth G.S., et al. Assessment: botulinum neurotoxin in the treatment of autonomic disorders and pain (an evidence-based review): report of the therapeutics and technology assessment subcommittee of the American academy of neurology. Neurology 2008, 70(May (19)):1707-1714.
    • (2008) Neurology , vol.70 , Issue.MAY 19 , pp. 1707-1714
    • Naumann, M.1    So, Y.2    Argoff, C.E.3    Childers, M.K.4    Dykstra, D.D.5    Gronseth, G.S.6
  • 6
    • 75549083527 scopus 로고    scopus 로고
    • Pathema: a clade-specific bioinformatics resource center for pathogen research
    • Brinkac L.M., Davidsen T., Beck E., Ganapathy A., Caler E., Dodson R.J., et al. Pathema: a clade-specific bioinformatics resource center for pathogen research. Nucleic Acids Res 2009, 38(January (Database issue)):D408-D414.
    • (2009) Nucleic Acids Res , vol.38 , Issue.JANUARY DATABASE ISSUE
    • Brinkac, L.M.1    Davidsen, T.2    Beck, E.3    Ganapathy, A.4    Caler, E.5    Dodson, R.J.6
  • 7
    • 0027379492 scopus 로고
    • Sequence of the gene coding for the neurotoxin of Clostridium botulinum type A associated with infant botulism: comparison with other clostridial neurotoxins
    • Willems A., East A.K., Lawson P.A., Collins M.D. Sequence of the gene coding for the neurotoxin of Clostridium botulinum type A associated with infant botulism: comparison with other clostridial neurotoxins. Res Microbiol 1993, 144(September (7)):547-556.
    • (1993) Res Microbiol , vol.144 , Issue.SEPTEMBER 7 , pp. 547-556
    • Willems, A.1    East, A.K.2    Lawson, P.A.3    Collins, M.D.4
  • 8
    • 2442690587 scopus 로고    scopus 로고
    • Nucleotide sequence and transcriptional analysis of the type A2 neurotoxin gene cluster in Clostridium botulinum
    • Dineen S.S., Bradshaw M., Karasek C.E., Johnson E.A. Nucleotide sequence and transcriptional analysis of the type A2 neurotoxin gene cluster in Clostridium botulinum. FEMS Microbiol Lett 2004, 235(June (1)):9-16.
    • (2004) FEMS Microbiol Lett , vol.235 , Issue.JUNE 1 , pp. 9-16
    • Dineen, S.S.1    Bradshaw, M.2    Karasek, C.E.3    Johnson, E.A.4
  • 9
    • 76149138491 scopus 로고    scopus 로고
    • Expression of the Clostridium botulinum A2 neurotoxin gene cluster proteins and characterization of the A2 complex
    • Lin G., Tepp W.H., Pier C.L., Jacobson M.J., Johnson E.A. Expression of the Clostridium botulinum A2 neurotoxin gene cluster proteins and characterization of the A2 complex. Appl Environ Microbiol 2010, 76(January (1)):40-47.
    • (2010) Appl Environ Microbiol , vol.76 , Issue.JANUARY 1 , pp. 40-47
    • Lin, G.1    Tepp, W.H.2    Pier, C.L.3    Jacobson, M.J.4    Johnson, E.A.5
  • 10
    • 64849090643 scopus 로고    scopus 로고
    • Catalytic properties of botulinum neurotoxin subtypes A3 and A4 (dagger)
    • Henkel J.S., Jacobson M., Tepp W., Pier C., Johnson E.A., Barbieri J.T. Catalytic properties of botulinum neurotoxin subtypes A3 and A4 (dagger). Biochemistry 2009, 48(March (11)):2522-2528.
    • (2009) Biochemistry , vol.48 , Issue.MARCH 11 , pp. 2522-2528
    • Henkel, J.S.1    Jacobson, M.2    Tepp, W.3    Pier, C.4    Johnson, E.A.5    Barbieri, J.T.6
  • 11
    • 78650885033 scopus 로고    scopus 로고
    • Botulinum neurotoxin subtype A2 enters neuronal cells faster than subtype A1
    • Pier C.L., Chen C., Tepp W.H., Lin G., Janda K.D., Barbieri J.T., et al. Botulinum neurotoxin subtype A2 enters neuronal cells faster than subtype A1. FEBS Lett 2011, 585(January (1)):199-206.
    • (2011) FEBS Lett , vol.585 , Issue.JANUARY 1 , pp. 199-206
    • Pier, C.L.1    Chen, C.2    Tepp, W.H.3    Lin, G.4    Janda, K.D.5    Barbieri, J.T.6
  • 12
    • 78650679298 scopus 로고    scopus 로고
    • Comparison of effects of botulinum toxin subtype A1 and A2 using twitch tension assay and rat grip strength test
    • Torii Y., Kiyota N., Sugimoto N., Mori Y., Goto Y., Harakawa T., et al. Comparison of effects of botulinum toxin subtype A1 and A2 using twitch tension assay and rat grip strength test. Toxicon 2011, 57(January (1)):93-99.
    • (2011) Toxicon , vol.57 , Issue.JANUARY 1 , pp. 93-99
    • Torii, Y.1    Kiyota, N.2    Sugimoto, N.3    Mori, Y.4    Goto, Y.5    Harakawa, T.6
  • 13
    • 0017548443 scopus 로고
    • Case of infant botulism in Texas
    • Edmond B.J., Guerra F.A., Blake J., Hempler S. Case of infant botulism in Texas. Tex Med 1977, 73(October (10)):85-88.
    • (1977) Tex Med , vol.73 , Issue.OCTOBER 10 , pp. 85-88
    • Edmond, B.J.1    Guerra, F.A.2    Blake, J.3    Hempler, S.4
  • 15
    • 38049093742 scopus 로고    scopus 로고
    • Botulinum neurotoxin vaccines: past, present, and future
    • Smith L.A., Rusnak J.M. Botulinum neurotoxin vaccines: past, present, and future. Crit Rev Immunol 2007, 27(4):303-318.
    • (2007) Crit Rev Immunol , vol.27 , Issue.4 , pp. 303-318
    • Smith, L.A.1    Rusnak, J.M.2
  • 16
    • 67650045501 scopus 로고    scopus 로고
    • Novel Clostridium botulinum toxin gene arrangement with subtype A5 and partial subtype B3 botulinum neurotoxin genes
    • Dover N., Barash J.R., Arnon S.S. Novel Clostridium botulinum toxin gene arrangement with subtype A5 and partial subtype B3 botulinum neurotoxin genes. J Clin Microbiol 2009, 47(July (7)):2349-2350.
    • (2009) J Clin Microbiol , vol.47 , Issue.JULY 7 , pp. 2349-2350
    • Dover, N.1    Barash, J.R.2    Arnon, S.S.3
  • 17
    • 65349103916 scopus 로고    scopus 로고
    • Independent evolution of neurotoxin and flagellar genetic loci in proteolytic Clostridium botulinum
    • Carter A.T., Paul C.J., Mason D.R., Twine S.M., Alston M.J., Logan S.M., et al. Independent evolution of neurotoxin and flagellar genetic loci in proteolytic Clostridium botulinum. BMC Genomics 2009, 10:115.
    • (2009) BMC Genomics , vol.10 , pp. 115
    • Carter, A.T.1    Paul, C.J.2    Mason, D.R.3    Twine, S.M.4    Alston, M.J.5    Logan, S.M.6
  • 18
    • 79960085306 scopus 로고    scopus 로고
    • Purification, modeling and analysis of neurotoxin BoNT/A5 from Clostridium botulinum strain A661222
    • Jacobson M.J., Lin G., Tepp W., Dupuy J., Stenmark P., Stevens R.C., et al. Purification, modeling and analysis of neurotoxin BoNT/A5 from Clostridium botulinum strain A661222. Appl Environ Microbiol 2011, April.
    • (2011) Appl Environ Microbiol , Issue.APRIL
    • Jacobson, M.J.1    Lin, G.2    Tepp, W.3    Dupuy, J.4    Stenmark, P.5    Stevens, R.C.6
  • 19
    • 46149134882 scopus 로고
    • How do tetanus and botulinum toxins bind to neuronal membranes?
    • Montecucco C. How do tetanus and botulinum toxins bind to neuronal membranes?. Trends Biochem Sci 1986, 11(August (8)):314-317.
    • (1986) Trends Biochem Sci , vol.11 , Issue.AUGUST 8 , pp. 314-317
    • Montecucco, C.1
  • 20
    • 50849107858 scopus 로고    scopus 로고
    • Crystal structure of botulinum neurotoxin type A in complex with the cell surface co-receptor GT1b-insight into the toxin-neuron interaction
    • Stenmark P., Dupuy J., Imamura A., Kiso M., Stevens R.C. Crystal structure of botulinum neurotoxin type A in complex with the cell surface co-receptor GT1b-insight into the toxin-neuron interaction. PLoS Pathog 2008, 4(8):e1000129.
    • (2008) PLoS Pathog , vol.4 , Issue.8
    • Stenmark, P.1    Dupuy, J.2    Imamura, A.3    Kiso, M.4    Stevens, R.C.5
  • 21
    • 0030064241 scopus 로고    scopus 로고
    • The high-affinity binding of Clostridium botulinum type B neurotoxin to synaptotagmin II associated with gangliosides GT1b/GD1a
    • Nishiki T., Tokuyama Y., Kamata Y., Nemoto Y., Yoshida A., Sato K., et al. The high-affinity binding of Clostridium botulinum type B neurotoxin to synaptotagmin II associated with gangliosides GT1b/GD1a. FEBS Lett 1996, 378(January (3)):253-257.
    • (1996) FEBS Lett , vol.378 , Issue.JANUARY 3 , pp. 253-257
    • Nishiki, T.1    Tokuyama, Y.2    Kamata, Y.3    Nemoto, Y.4    Yoshida, A.5    Sato, K.6
  • 22
    • 0141641129 scopus 로고    scopus 로고
    • Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells
    • Dong M., Richards D.A., Goodnough M.C., Tepp W.H., Johnson E.A., Chapman E.R. Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells. J Cell Biol 2003, 162(September (7)):1293-1303.
    • (2003) J Cell Biol , vol.162 , Issue.SEPTEMBER 7 , pp. 1293-1303
    • Dong, M.1    Richards, D.A.2    Goodnough, M.C.3    Tepp, W.H.4    Johnson, E.A.5    Chapman, E.R.6
  • 23
    • 33646248918 scopus 로고    scopus 로고
    • SV2 is the protein receptor for botulinum neurotoxin A
    • Dong M., Yeh F., Tepp W.H., Dean C., Johnson E.A., Janz R., et al. SV2 is the protein receptor for botulinum neurotoxin A. Science 2006, 312(April (5773)):592-596.
    • (2006) Science , vol.312 , Issue.APRIL 5773 , pp. 592-596
    • Dong, M.1    Yeh, F.2    Tepp, W.H.3    Dean, C.4    Johnson, E.A.5    Janz, R.6
  • 24
    • 58549094719 scopus 로고    scopus 로고
    • Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons
    • Dong M., Liu H., Tepp W.H., Johnson E.A., Janz R., Chapman E.R. Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons. Mol Biol Cell 2008, 19(December (12)):5226-5237.
    • (2008) Mol Biol Cell , vol.19 , Issue.DECEMBER 12 , pp. 5226-5237
    • Dong, M.1    Liu, H.2    Tepp, W.H.3    Johnson, E.A.4    Janz, R.5    Chapman, E.R.6
  • 25
    • 67649210455 scopus 로고    scopus 로고
    • Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
    • Fu Z., Chen C., Barbieri J.T., Kim J.J., Baldwin M.R. Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F. Biochemistry 2009, May.
    • (2009) Biochemistry , Issue.MAY
    • Fu, Z.1    Chen, C.2    Barbieri, J.T.3    Kim, J.J.4    Baldwin, M.R.5
  • 27
    • 75449125388 scopus 로고
    • Studies on immunity to toxins of Clostridium botulinum. Ix. Immunologic response of man to purified pentavalent abcde botulinum toxiod
    • Fiock M.A., Cardella M.A., Gearinger N.F. Studies on immunity to toxins of Clostridium botulinum. Ix. Immunologic response of man to purified pentavalent abcde botulinum toxiod. J Immunol 1963, 90(May):697-702.
    • (1963) J Immunol , vol.90 , Issue.MAY , pp. 697-702
    • Fiock, M.A.1    Cardella, M.A.2    Gearinger, N.F.3
  • 28
    • 0029039466 scopus 로고
    • Protective vaccination with a recombinant fragment of Clostridium botulinum neurotoxin serotype A expressed from a synthetic gene in Escherichia coli
    • Clayton M.A., Clayton J.M., Brown D.R., Middlebrook J.L. Protective vaccination with a recombinant fragment of Clostridium botulinum neurotoxin serotype A expressed from a synthetic gene in Escherichia coli. Infect Immun 1995, 63(July (7)):2738-2742.
    • (1995) Infect Immun , vol.63 , Issue.JULY 7 , pp. 2738-2742
    • Clayton, M.A.1    Clayton, J.M.2    Brown, D.R.3    Middlebrook, J.L.4
  • 29
    • 0031658344 scopus 로고    scopus 로고
    • Purification, potency, and efficacy of the botulinum neurotoxin type A binding domain from Pichia pastoris as a recombinant vaccine candidate
    • Byrne M.P., Smith T.J., Montgomery V.A., Smith L.A. Purification, potency, and efficacy of the botulinum neurotoxin type A binding domain from Pichia pastoris as a recombinant vaccine candidate. Infect Immun 1998, 66(October (10)):4817-4822.
    • (1998) Infect Immun , vol.66 , Issue.OCTOBER 10 , pp. 4817-4822
    • Byrne, M.P.1    Smith, T.J.2    Montgomery, V.A.3    Smith, L.A.4
  • 31
    • 4143073791 scopus 로고    scopus 로고
    • Interaction between the two subdomains of the C-terminal part of the botulinum neurotoxin A is essential for the generation of protective antibodies
    • Tavallaie M., Chenal A., Gillet D., Pereira Y., Manich M., Gibert M., et al. Interaction between the two subdomains of the C-terminal part of the botulinum neurotoxin A is essential for the generation of protective antibodies. FEBS Lett 2004, 572(August (1-3)):299-306.
    • (2004) FEBS Lett , vol.572 , Issue.AUGUST 13 , pp. 299-306
    • Tavallaie, M.1    Chenal, A.2    Gillet, D.3    Pereira, Y.4    Manich, M.5    Gibert, M.6
  • 32
    • 77950859996 scopus 로고    scopus 로고
    • Botulism and vaccines for its prevention
    • Smith L.A. Botulism and vaccines for its prevention. Vaccine 2009, 27(November (Suppl. 4)):D33-D39.
    • (2009) Vaccine , vol.27 , Issue.NOVEMBER SUPPL. 4
    • Smith, L.A.1
  • 33
    • 77951018634 scopus 로고    scopus 로고
    • Mode of action of botulinum neurotoxins: current vaccination strategies and molecular immune recognition
    • Aoki K.R., Smith L.A., Atassi M.Z. Mode of action of botulinum neurotoxins: current vaccination strategies and molecular immune recognition. Crit Rev Immunol 2010, 30(2):167-187.
    • (2010) Crit Rev Immunol , vol.30 , Issue.2 , pp. 167-187
    • Aoki, K.R.1    Smith, L.A.2    Atassi, M.Z.3
  • 34
    • 25444446822 scopus 로고    scopus 로고
    • Characterization of the antibody response to the receptor binding domain of botulinum neurotoxin serotypes A and E
    • Baldwin M.R., Tepp W.H., Pier C.L., Bradshaw M., Ho M., Wilson B.A., et al. Characterization of the antibody response to the receptor binding domain of botulinum neurotoxin serotypes A and E. Infect Immun 2005, 73(October (10)):6998-7005.
    • (2005) Infect Immun , vol.73 , Issue.OCTOBER 10 , pp. 6998-7005
    • Baldwin, M.R.1    Tepp, W.H.2    Pier, C.L.3    Bradshaw, M.4    Ho, M.5    Wilson, B.A.6
  • 35
    • 78649331561 scopus 로고    scopus 로고
    • Purification of a recombinant heavy chain fragment C vaccine candidate against botulinum serotype C neurotoxin [rBoNTC(H(c))] expressed in Pichia pastoris
    • Dux M.P., Huang J., Barent R., Inan M., Swanson S.T., Sinha J., et al. Purification of a recombinant heavy chain fragment C vaccine candidate against botulinum serotype C neurotoxin [rBoNTC(H(c))] expressed in Pichia pastoris. Protein Expres Purif 2011, 75(February (2)):177-185.
    • (2011) Protein Expres Purif , vol.75 , Issue.FEBRUARY 2 , pp. 177-185
    • Dux, M.P.1    Huang, J.2    Barent, R.3    Inan, M.4    Swanson, S.T.5    Sinha, J.6
  • 36
    • 77951985187 scopus 로고    scopus 로고
    • Efficacy of a potential trivalent vaccine based on Hc fragments of botulinum toxins A, B, and E produced in a cell-free expression system
    • Zichel R., Mimran A., Keren A., Barnea A., Steinberger-Levy I., Marcus D., et al. Efficacy of a potential trivalent vaccine based on Hc fragments of botulinum toxins A, B, and E produced in a cell-free expression system. Clin Vaccine Immunol 2010, 17(May (5)):784-792.
    • (2010) Clin Vaccine Immunol , vol.17 , Issue.MAY 5 , pp. 784-792
    • Zichel, R.1    Mimran, A.2    Keren, A.3    Barnea, A.4    Steinberger-Levy, I.5    Marcus, D.6
  • 37
    • 34249879558 scopus 로고    scopus 로고
    • Trivalent vaccine against botulinum toxin serotypes A, B, and E that can be administered by the mucosal route
    • Ravichandran E., Al-Saleem F.H., Ancharski D.M., Elias M.D., Singh A.K., Shamim M., et al. Trivalent vaccine against botulinum toxin serotypes A, B, and E that can be administered by the mucosal route. Infect Immun 2007, 75(June (6)):3043-3054.
    • (2007) Infect Immun , vol.75 , Issue.JUNE 6 , pp. 3043-3054
    • Ravichandran, E.1    Al-Saleem, F.H.2    Ancharski, D.M.3    Elias, M.D.4    Singh, A.K.5    Shamim, M.6
  • 38
    • 34247362076 scopus 로고    scopus 로고
    • C terminal half fragment (50kDa) of heavy chain components of Clostridium botulinum type C and D neurotoxins can be used as an effective vaccine
    • Lee J.C., Hwang H.J., Sakaguchi Y., Yamamoto Y., Arimitsu H., Tsuji T., et al. C terminal half fragment (50kDa) of heavy chain components of Clostridium botulinum type C and D neurotoxins can be used as an effective vaccine. Microbiol Immunol 2007, 51(4):445-455.
    • (2007) Microbiol Immunol , vol.51 , Issue.4 , pp. 445-455
    • Lee, J.C.1    Hwang, H.J.2    Sakaguchi, Y.3    Yamamoto, Y.4    Arimitsu, H.5    Tsuji, T.6
  • 39
    • 4043119057 scopus 로고    scopus 로고
    • Progress toward development of an inhalation vaccine against botulinum toxin
    • Park J.B., Simpson L.L. Progress toward development of an inhalation vaccine against botulinum toxin. Expert Rev Vaccines 2004, 3(August (4)):477-487.
    • (2004) Expert Rev Vaccines , vol.3 , Issue.AUGUST 4 , pp. 477-487
    • Park, J.B.1    Simpson, L.L.2
  • 40
    • 0028922592 scopus 로고
    • Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins
    • Schiavo G., Shone C.C., Bennett M.K., Scheller R.H., Montecucco C. Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins. J Biol Chem 1995, 270(May (18)):10566-10570.
    • (1995) J Biol Chem , vol.270 , Issue.MAY 18 , pp. 10566-10570
    • Schiavo, G.1    Shone, C.C.2    Bennett, M.K.3    Scheller, R.H.4    Montecucco, C.5
  • 41
    • 67649378415 scopus 로고    scopus 로고
    • Production of catalytically inactive BoNT/A1 holoprotein and comparison with BoNT/A1 subunit vaccines against toxin subtypes A1, A2, and A3
    • Webb R.P., Smith T.J., Wright P., Brown J., Smith L.A. Production of catalytically inactive BoNT/A1 holoprotein and comparison with BoNT/A1 subunit vaccines against toxin subtypes A1, A2, and A3. Vaccine 2009, 27(July (33)):4490-4497.
    • (2009) Vaccine , vol.27 , Issue.JULY 33 , pp. 4490-4497
    • Webb, R.P.1    Smith, T.J.2    Wright, P.3    Brown, J.4    Smith, L.A.5
  • 43
    • 0033958809 scopus 로고    scopus 로고
    • DNA vaccination using the fragment C of botulinum neurotoxin type A provided protective immunity in mice
    • Shyu R.H., Shaio M.F., Tang S.S., Shyu H.F., Lee C.F., Tsai M.H., et al. DNA vaccination using the fragment C of botulinum neurotoxin type A provided protective immunity in mice. J Biomed Sci 2000, 7(January-February (1)):51-57.
    • (2000) J Biomed Sci , vol.7 , Issue.JANUARY FEBRUARY 1 , pp. 51-57
    • Shyu, R.H.1    Shaio, M.F.2    Tang, S.S.3    Shyu, H.F.4    Lee, C.F.5    Tsai, M.H.6
  • 44
    • 79551595130 scopus 로고    scopus 로고
    • Enhancement of the immunogenicity of DNA replicon vaccine of Clostridium botulinum neurotoxin serotype A by GM-CSF gene adjuvant
    • Li N., Yu Y.Z., Yu W.Y., Sun Z.W. Enhancement of the immunogenicity of DNA replicon vaccine of Clostridium botulinum neurotoxin serotype A by GM-CSF gene adjuvant. Immunopharmacol Immunotoxicol 2011, 33(March (1)):211-219.
    • (2011) Immunopharmacol Immunotoxicol , vol.33 , Issue.MARCH 1 , pp. 211-219
    • Li, N.1    Yu, Y.Z.2    Yu, W.Y.3    Sun, Z.W.4
  • 45
    • 34247325141 scopus 로고    scopus 로고
    • Protection with recombinant Clostridium botulinum C1 and D binding domain subunit (Hc) vaccines against C and D neurotoxins
    • Webb R.P., Smith T.J., Wright P.M., Montgomery V.A., Meagher M.M., Smith L.A. Protection with recombinant Clostridium botulinum C1 and D binding domain subunit (Hc) vaccines against C and D neurotoxins. Vaccine 2007, 25(May (21)):4273-4282.
    • (2007) Vaccine , vol.25 , Issue.MAY 21 , pp. 4273-4282
    • Webb, R.P.1    Smith, T.J.2    Wright, P.M.3    Montgomery, V.A.4    Meagher, M.M.5    Smith, L.A.6
  • 46
    • 0020955120 scopus 로고
    • Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation
    • Huttner W.B., Schiebler W., Greengard P., De Camilli P. Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J Cell Biol 1983, 96(May (5)):1374-1388.
    • (1983) J Cell Biol , vol.96 , Issue.MAY 5 , pp. 1374-1388
    • Huttner, W.B.1    Schiebler, W.2    Greengard, P.3    De Camilli, P.4
  • 47
    • 33846598840 scopus 로고    scopus 로고
    • Genetic diversity among botulinum neurotoxin-producing clostridial strains
    • Hill K.K., Smith T.J., Helma C.H., Ticknor L.O., Foley B.T., Svensson R.T., et al. Genetic diversity among botulinum neurotoxin-producing clostridial strains. J Bacteriol 2007, 189(February (3)):818-832.
    • (2007) J Bacteriol , vol.189 , Issue.FEBRUARY 3 , pp. 818-832
    • Hill, K.K.1    Smith, T.J.2    Helma, C.H.3    Ticknor, L.O.4    Foley, B.T.5    Svensson, R.T.6
  • 48
    • 0024370444 scopus 로고
    • Gangliosides mediate inhibitory effects of tetanus and botulinum A neurotoxins on exocytosis in chromaffin cells
    • Marxen P., Fuhrmann U., Bigalke H. Gangliosides mediate inhibitory effects of tetanus and botulinum A neurotoxins on exocytosis in chromaffin cells. Toxicon 1989, 27(8):849-859.
    • (1989) Toxicon , vol.27 , Issue.8 , pp. 849-859
    • Marxen, P.1    Fuhrmann, U.2    Bigalke, H.3
  • 49
    • 1242320307 scopus 로고    scopus 로고
    • The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction
    • Rummel A., Mahrhold S., Bigalke H., Binz T. The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction. Mol Microbiol 2004, 51(February (3)):631-643.
    • (2004) Mol Microbiol , vol.51 , Issue.FEBRUARY 3 , pp. 631-643
    • Rummel, A.1    Mahrhold, S.2    Bigalke, H.3    Binz, T.4
  • 50
    • 33748777674 scopus 로고    scopus 로고
    • Mapping of the regions on the heavy chain of botulinum neurotoxin A (BoNT/A) recognized by antibodies of cervical dystonia patients with immunoresistance to BoNT/A
    • Dolimbek B.Z., Aoki K.R., Steward L.E., Jankovic J., Atassi M.Z. Mapping of the regions on the heavy chain of botulinum neurotoxin A (BoNT/A) recognized by antibodies of cervical dystonia patients with immunoresistance to BoNT/A. Mol Immunol 2007, 44(February (5)):1029-1041.
    • (2007) Mol Immunol , vol.44 , Issue.FEBRUARY 5 , pp. 1029-1041
    • Dolimbek, B.Z.1    Aoki, K.R.2    Steward, L.E.3    Jankovic, J.4    Atassi, M.Z.5
  • 51
    • 23944468631 scopus 로고    scopus 로고
    • Persistence of zinc-binding bacterial superantigens at the surface of antigen-presenting cells contributes to the extreme potency of these superantigens as T-cell activators
    • Pless D.D., Reinke R.G., Ulrich E.K., Bavari R.G.S. Persistence of zinc-binding bacterial superantigens at the surface of antigen-presenting cells contributes to the extreme potency of these superantigens as T-cell activators. Infect Immun 2005, 73:5358-5366.
    • (2005) Infect Immun , vol.73 , pp. 5358-5366
    • Pless, D.D.1    Reinke, R.G.2    Ulrich, E.K.3    Bavari, R.G.S.4
  • 52
    • 0030294098 scopus 로고    scopus 로고
    • Mapping of protective and cross-reactive domains of the type A neurotoxin of Clostridium botulinum
    • Dertzbaugh M.T., West M.W. Mapping of protective and cross-reactive domains of the type A neurotoxin of Clostridium botulinum. Vaccine 1996, 14(November (16)):1538-1544.
    • (1996) Vaccine , vol.14 , Issue.NOVEMBER 16 , pp. 1538-1544
    • Dertzbaugh, M.T.1    West, M.W.2
  • 53
    • 0035851374 scopus 로고    scopus 로고
    • Temporal nucleotide changes in pertactin and pertussis toxin genes in Bordetella pertussis strains isolated from clinical cases in Poland
    • Gzyl A., Augustynowicz E., van Loo I., Slusarczyk J. Temporal nucleotide changes in pertactin and pertussis toxin genes in Bordetella pertussis strains isolated from clinical cases in Poland. Vaccine 2001, 20(November (3-4)):299-303.
    • (2001) Vaccine , vol.20 , Issue.NOVEMBER 34 , pp. 299-303
    • Gzyl, A.1    Augustynowicz, E.2    van Loo, I.3    Slusarczyk, J.4
  • 54
    • 2442435729 scopus 로고    scopus 로고
    • Sequence variation in pertussis S1 subunit toxin and pertussis genes in Bordetella pertussis strains used for the whole-cell pertussis vaccine produced in Poland since 1960: efficiency of the DTwP vaccine-induced immunity against currently circulating B. pertussis isolates
    • Gzyl A., Augustynowicz E., Gniadek G., Rabczenko D., Dulny G., Slusarczyk J. Sequence variation in pertussis S1 subunit toxin and pertussis genes in Bordetella pertussis strains used for the whole-cell pertussis vaccine produced in Poland since 1960: efficiency of the DTwP vaccine-induced immunity against currently circulating B. pertussis isolates. Vaccine 2004, 22(June (17-18)):2122-2128.
    • (2004) Vaccine , vol.22 , Issue.JUNE 1718 , pp. 2122-2128
    • Gzyl, A.1    Augustynowicz, E.2    Gniadek, G.3    Rabczenko, D.4    Dulny, G.5    Slusarczyk, J.6
  • 55
    • 33644938884 scopus 로고    scopus 로고
    • Comparison of real-time PCR and pyrosequencing for typing Bordetella pertussis toxin subunit 1 variants
    • Storm M., Advani A., Pettersson M., Hallander H.O., Bondeson K. Comparison of real-time PCR and pyrosequencing for typing Bordetella pertussis toxin subunit 1 variants. J Microbiol Methods 2006, 65(April (1)):153-158.
    • (2006) J Microbiol Methods , vol.65 , Issue.APRIL 1 , pp. 153-158
    • Storm, M.1    Advani, A.2    Pettersson, M.3    Hallander, H.O.4    Bondeson, K.5
  • 56
    • 1942422576 scopus 로고    scopus 로고
    • Organization and regulation of the neurotoxin genes in Clostridium botulinum and Clostridium tetani
    • Raffestin S., Marvaud J.C., Cerrato R., Dupuy B., Popoff M.R. Organization and regulation of the neurotoxin genes in Clostridium botulinum and Clostridium tetani. Anaerobe 2004, 10(April (2)):93-100.
    • (2004) Anaerobe , vol.10 , Issue.APRIL 2 , pp. 93-100
    • Raffestin, S.1    Marvaud, J.C.2    Cerrato, R.3    Dupuy, B.4    Popoff, M.R.5
  • 57
    • 34547133039 scopus 로고    scopus 로고
    • Plasmid encoded neurotoxin genes in Clostridium botulinum serotype A subtypes
    • Marshall K.M., Bradshaw M., Pellett S., Johnson E.A. Plasmid encoded neurotoxin genes in Clostridium botulinum serotype A subtypes. Biochem Biophys Res Commun 2007, 361(September (1)):49-54.
    • (2007) Biochem Biophys Res Commun , vol.361 , Issue.SEPTEMBER 1 , pp. 49-54
    • Marshall, K.M.1    Bradshaw, M.2    Pellett, S.3    Johnson, E.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.