Botulinum neurotoxin subtype A2 enters neuronal cells faster than subtype A1

FEBS Letters

Volumn 585, Issue 1, 2011, Pages 199-206

  Pier, Christina L ^a   Chen, Chen ^b   Tepp, William H ^a   Lin, Guangyun ^a   Janda, Kim D ^c   Barbieri, Joseph T ^b   Pellett, Sabine ^a   Johnson, Eric A ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

BoNT A1; BoNT A2; Botulinum neurotoxin; Cell based assay; Cell entry; Neuron

Indexed keywords

BOTULINUM TOXIN A; BOTULINUM TOXIN A1; BOTULINUM TOXIN A2; GANGLIOSIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; NERVE CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN TRANSPORT; RAT; TOXIN ANALYSIS; TRANSPORT KINETICS;

ANIMALS; BLOTTING, WESTERN; BOTULINUM TOXINS, TYPE A; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GANGLIOSIDES; HYDROLYSIS; MICROSCOPY, FLUORESCENCE; NEURONS; PROTEIN BINDING; RAB5 GTP-BINDING PROTEINS; RATS; SPINAL CORD; SYNAPTOPHYSIN; SYNAPTOSOMAL-ASSOCIATED PROTEIN 25; TIME FACTORS;

EID: 78650885033     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.11.045     Document Type: Article

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