Nucleophosmin deposition during mRNA 3′ end processing influences poly(A) tail length

EMBO Journal

Volumn 30, Issue 19, 2011, Pages 3994-4005

  Sagawa, Fumihiko ^a   Ibrahim, Hend ^a   Morrison, Angela L ^a   Wilusz, Carol J ^a   Wilusz, Jeffrey ^a  

^a Department of Ecosystem Science and Sustainability   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NUCLEOPHOSMIN; POLYADENYLIC ACID;

ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; IMMUNOPRECIPITATION; NUCLEOTIDE SEQUENCE; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROCESSING; PROTEIN SYNTHESIS;

CELL LINE; CELL NUCLEUS; HELA CELLS; HUMANS; JURKAT CELLS; MRNA CLEAVAGE AND POLYADENYLATION FACTORS; NUCLEAR PROTEINS; PLASMIDS; POLY A; POLYADENYLATION; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 80053592213     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.272     Document Type: Article

References (54)

1. Abad X, Vera M, Jung SP, Oswald E, Romero I, Amin V, Fortes P, Gunderson SI (2008) Requirements for gene silencing mediated by U1 snRNA binding to a target sequence. Nucleic Acids Res 36: 2338-2352 (Pubitemid 351567007)
2. Bienroth S, Keller W, Wahle E (1993) Assembly of a processive messenger RNA polyadenylation complex. EMBO J 12: 585-594 (Pubitemid 23073704)
3. Brady SN, Maggi Jr LB, Winkeler CL, Toso EA, Gwinn AS, Pelletier CL, Weber JD (2009) Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation. Oncogene 28: 3209-3220
4. Brown CE, Tarun Jr SZ, Boeck R, Sachs AB (1996) PAN3 encodes a subunit of the Pab1p-dependent poly(A) nuclease in Saccharomyces cerevisiae. Mol Cell Biol 16: 5744-5753 (Pubitemid 26315095)
5. 0 processing in response to DNA damage. EMBO J 29: 1674-1687.
6. 0 splice site similarly affect polyadenylation efficiency. Mol Cell Biol 16: 2579-2584
7. Crockett DK, Lin Z, Elenitoba-Johnson KS, Lim MS (2004) Identification of NPM-ALK interacting proteins by tandem mass spectrometry. Oncogene 23: 2617-2629 (Pubitemid 38586315)
8. Falini, B Nicoletti I, Bolli N, Martelli MP, Liso A, Gorello P, Mandelli F, Mecucci C, Martelli MF (2007) Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemias. Haematologica 92: 519-532 (Pubitemid 350144298)
9. Fankhauser C, Izaurralde E, Adachi Y, Wingfield P, Laemmli UK (1991) Specific complex of human immunodeficiency virus type 1 rev and nucleolar B23 proteins: dissociation by the Rev response element. Mol Cell Biol 11 : 2567-2575 (Pubitemid 21895636)
10. 0 processing. Proc Natl Acad Sci USA 94: 11893-11898
11. 0 untranslated region of sindbis virus represses deadenylation of viral transcripts in mosquito and mammalian cells. J Virol 82: 880-892
12. 0-flanking sequence of the bovine growth hormone gene contains novel elements required for efficient and accurate polyadenylation. J Biol Chem 267: 16330-16334
13. Grisendi S, Bernardi R, Rossi M, Cheng K, Khandker L, Manova K, Pandolfi PP (2005) Role of nucleophosmin in embryonic development and tumorigenesis. Nature 437: 147-153 (Pubitemid 41613442)
14. Grisendi S, Mecucci C, Falini B, Pandolfi PP (2006) Nucleophosmin and cancer. Nat Rev Cancer 6: 493-505 (Pubitemid 43980539)
15. Gu H, Das Gupta J, Schoenberg DR (1999) The poly(A)-limiting element is a conserved cis-acting sequence that regulates poly(A) tail length on nuclear pre-mRNAs. Proc Natl Acad Sci USA 96: 8943-8948 (Pubitemid 29374687)
16. 0 end processing. Mol Cell Biol 31: 639-651
17. Haindl M, Harasim T, Eick D, Muller S (2008) The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing. EMBO Rep 9: 273-279 (Pubitemid 351330993)
18. 0-UTR. RNA 13: 1103-1115 (Pubitemid 46984900)
19. Hisaoka M, Ueshima S, Murano K, Nagata K, Okuwaki M (2010) Regulation of nucleolar chromatin by B23/nucleophosmin jointly depends upon its RNA binding activity and transcription factor UBF. Mol Cell Biol 30: 4952-4964
20. Jensen TH, Patricio K, McCarthy T, Rosbash M (2001) A block to mRNA nuclear export in S. cerevisiae leads to hyperadenylation of transcripts that accumulate at the site of transcription. Mol Cell 7: 887-898 (Pubitemid 32436448)
21. 0 untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development. Proc Natl Acad Sci USA 106: 7028-7033
22. 0 end processing factor Pcf11. Mol Cell 33: 215-226
23. Kaida D, Berg MG, Younis I, Kasim M, Singh LN, Wan L, Dreyfuss G (2010) U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation. Nature 468: 664-668
24. Kühn U, Gündel M, Knoth A, Kerwitz Y, Rüdel S, Wahle E (2009) Poly(A) tail length is controlled by the nuclear poly(A)-binding protein regulating the interaction between poly(A) polymerase and the cleavage and polyadenylation specificity factor. J Biol Chem 284: 22803-22814
25. Li Z, Hann SR (2009) The Myc-nucleophosmin-ARF network: a complex web unveiled. Cell Cycle 8: 2703-2707
26. Lin CY, Tan BC, Liu H, Shih CJ, Chien KY, Lin CL, Yung BY (2010) Dephosphorylation of nucleophosmin by PP1â facilitates pRB binding and consequent E2F1-dependent DNA repair. Mol Biol Cell 21 : 4409-4417
27. Lindström MS (2011) NPM1/B23: a multifunctional chaperone in ribosome biogenesis and chromatin remodeling. Biochem Res Int 2011: 195209.
28. Lunde BM, Reichow SL, Kim M, Suh H, Leeper TC, Yang F, Mutschler H, Buratowski S, Meinhart A, Varani G (2010) Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain. Nat Struct Mol Biol 17: 1195-1201.
29. Maggi Jr LB, Kuchenruether M, Dadey DY, Schwope RM, Grisendi S, Townsend RR, Pandolfi PP, Weber JD (2008) Nucleophosmin serves as a rate-limiting nuclear export chaperone for the mammalian ribosome. Mol Cell Biol 28: 7050-7065
30. 0 end processing and transcription initiation. Mol Cell 40: 410-422
31. 0UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 138: 673-684
32. Meani N, Alcalay M (2009) Role of nucleophosmin in acute myeloid leukemia. Expert Rev Anticancer Ther 9: 1283-1294
33. 0 end processing regulation. Nucleic Acids Res 38: 2757-2774
34. Nunes NM, Li W, Tian B, Furger A (2010) A functional human Poly(A) site requires only a potent DSE and an A-rich upstream sequence. EMBO J 29: 1523-1536
35. Okuwaki M (2008) The structure and functions of NPM1/Nucleophsmin/B23, a multifunctional nucleolar acidic protein. J Biochem 143: 441-448 (Pubitemid 351451762)
36. Palaniswamy V, Moraes KC, Wilusz CJ, Wilusz J (2006) Nucleophosmin is selectively deposited on mRNA during poly-adenylation. Nat Struct Mol Biol 13: 429-435 (Pubitemid 43881583)
37. Pianta A, Puppin C, Franzoni A, Fabbro D, Di Loreto C, Bulotta S, Deganuto M, Paron I, Tell G, Puxeddu E, Filetti S, Russo D, Damante G (2010) Nucleophosmin is overexpressed in thyroid tumors. Biochem Biophys Res Commun 397: 499-504
38. 0-end processing complex after polyadenylation. Mol Cell Biol 29: 5327-5338
39. Rizos H, McKenzie HA, Ayub AL, Woodruff S, Becker TM, Scurr LL, Stahl J, Kefford RF (2006) Physical and functional interaction of the p14ARF tumor suppressor with ribosomes. J Biol Chem 281: 38080-38088 (Pubitemid 46042111)
40. 0-end processing with gene-nuclear pore association. Cell 135: 308-321
41. 0 end processing factor CF I m 68 functions in mRNA export. Mol Biol Cell 20: 5211-5223
42. 0 untranslated regions and fewer microRNA target sites. Science 320: 1643-1647 (Pubitemid 351931255)
43. 0 processing complex. Mol Cell 33: 365-376
44. Tarapore P, Shinmura K, Suzuki H, Tokuyama Y, Kim SH, Mayeda A, Fukasawa K (2006) Thr199 phosphorylation targets nucleophos-min to nuclear speckles and represses pre-mRNA processing. FEBS Lett 580: 399-409 (Pubitemid 43089663)
45. Tian B, Hu J, Zhang H, Lutz CS (2005) A large-scale analysis of mRNA polyadenylation of human and mouse genes. Nucleic Acids Res 33: 201-212 (Pubitemid 40276942)
46. Venkataraman K, Brown KM, Gilmartin GM (2005) Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognition. Genes Dev 19: 1315-1327 (Pubitemid 41003021)
47. Wahle E (1995) Poly(A) tail length control is caused by termination of processive synthesis. J Biol Chem 270: 2800-2808
48. Wang K, Zhang S, Weber J, Baxter D, Galas DJ (2010b) Export of microRNAs and microRNA-protective protein by mammalian cells. Nucleic Acids Res 38: 7248-7259
49. Wang Y, Fairley JA, Roberts SG (2010a) Phosphorylation of TFIIB links transcription initiation and termination. Curr Biol 20: 548-553
50. West S, Proudfoot NJ (2009) Transcriptional termination enhances protein expression in human cells. Mol Cell 33: 354-364
51. Wilusz J, Shenk T (1988) A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif. Cell 52: 221-228 (Pubitemid 18042858)
52. Wilusz JE, Beemon KL (2006) The negative regulator of splicing element of Rous sarcoma virus promotes polyadenylation. J Virol 80: 9634-9640 (Pubitemid 44435637)
53. Wu MH, Chang JH, Chou CC, Yung BY (2002) Involvement of nucleophosmin/B23 in the response of HeLa cells to UV irradiation. Int J Cancer 97: 297-305 (Pubitemid 34049019)
54. Yun C, Wang Y, Mukhopadhyay D, Backlund P, Kolli N, Yergey A, Wilkinson KD, Dasso M (2008) Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. J Cell Biol 183: 589-595