Nucleophosmin is overexpressed in thyroid tumors

Biochemical and Biophysical Research Communications

Volumn 397, Issue 3, 2010, Pages 499-504

  Pianta, Annalisa ^a   Puppin, Cinzia ^a   Franzoni, Alessandra ^b   Fabbro, Dora ^b   Di Loreto, Carla ^a   Bulotta, Stefania ^c   Deganuto, Marta ^a   Paron, Igor ^a   Tell, Gianluca ^a   Puxeddu, Efisio ^d   Filetti, Sebastiano ^e   Russo, Diego ^c   Damante, Giuseppe ^a,b  

^a UNIVERSITY OF UDINE   (Italy)

^b UNIVERSITY HOSPITAL OF UDINE   (Italy)

^c UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^d UNIVERSITY OF PERUGIA   (Italy)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Nucleophosmin; Thyroid cancer cell lines; Thyroid tumors

Indexed keywords

MESSENGER RNA; NUCLEOPHOSMIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ARTICLE; CANCER DIAGNOSIS; CARCINOGENESIS; CONTROLLED STUDY; FOLLICULAR CARCINOMA; GENE CONTROL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THYROID PAPILLARY CARCINOMA; TUMOR CELL; TUMOR CELL CULTURE; UNDIFFERENTIATED CARCINOMA;

CELL TRANSFORMATION, NEOPLASTIC; HUMANS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; THYROID GLAND; THYROID NEOPLASMS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 77954213973     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.05.142     Document Type: Article

References (24)

1. Borer R.A., Lehner C.F., Eppenberger H.M., Nigg E.A. Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell 1989, 56:379-390.
2. Grisendi S., Mecucci C., Falini B., Pandolfi P.P. Nucleophosmin and cancer. Nat. Rev. Cancer 2006, 6:493-505.
3. Falini B., Nicoletti I., Bolli N., Martelli M.P., Liso A., Gorello P., Mandelli F., Mecucci C., Martelli M.F. Translocation and mutations involving the nucleophosmin (NPM1) gene in limphomas and leukemias. Haematologica 2007, 92:519-532.
4. Skaar T.C., Prasad S.C., Sharareh S., Lippman M.E., Brünner N., Clarke R. Two-dimensional gel electrophoresis analyses identify nucleophosmin as an estrogen regulated protein associated with acquired estrogen independence in human breast cancer cells. J. Steroid Biochem. Mol. Biol. 1998, 67:391-402.
5. Shields L.B., Gerçel-Taylor C., Yashar C.M., Wan T.C., Katsanis W.A., Spinnato J.A., Taylor D.D. Induction of immune response to ovarian tumor antigens by multiparity. J. Soc. Gynecol. Investig. 1997, 4:298-304.
6. Nozawa Y., Van Belzen N., Van der Made A.C., Dinjens W.N., Bosman F.T. Expression of nucleophosmin/B23 in normal and neoplastic colorectal mucosa. J. Pathol. 1996, 178:48-52.
7. Tanaka M., Sasaki H., Kino I., Sugimura T., Terada M. Genes preferentially expressed in embryo stomach are predominantly expressed in gastric cancer. Cancer Res. 1992, 52:3372-3377.
8. Subong E.N., Shue M.J., Epstein J.I., Briggman J.V., Chan P.K., Partin A.W. Monoclonal antibody to prostate cancer nuclear matrix protein (PRO:4-216) recognizes nucleophosmin/B23. Prostate 1999, 39:298-304.
9. Tsui K.H., Cheng A.J., Chang P.L., Pan T.L., Yung B.Y. Association of nucleophosmin/B23 mRNA expression with clinical outcome in patients with bladder carcinoma. Urology 2004, 64:839-844.
10. Bernard K., Litman E., Fitzpatrick J.L., Shellman Y.G., Argast G., Polvinen K., Everett A.D., Fukasawa K., Norris D.A., Ahn N.G., Resing K.A. Functional proteomic analysis of melanoma progression. Cancer Res. 2003, 63:6716-6725.
11. Russo D., Arturi F., Bulotta S., Pellizzari L., Filetti S., Manzini G., Damante G., Tell G. Ape1/Ref-1 expression and cellular localization in human thyroid carcinoma cell lines. J. Endocrinol. Invest. 2001, 24:RC10-RC12.
12. Falini B., Mecucci C., Tiacci E., Alcalay M., Rosati R., Pasqualucci L., La Starza R., Diverio D., Colombo E., Santucci A., Bigerna B., Pacini R., Pucciarini A., Liso A., Vignetti M., Fazi P., Meani N., Pettirossi V., Saglio G., Mandelli F., Lo-Coco F., Pelicci P.G., Martelli M.F. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. N. Engl. J. Med. 2005, 352:254-266.
13. Ambesi-Impiombato F.S., Parks L.A., Coon H.G. Culture of hormone-dependent functional epithelial cells from rat thyroids. Proc. Natl. Acad. Sci. USA 1980, 77:3455-3459.
14. Russo D., Celano M., Bulotta S., Bruno R., Arturi F., Giannasio P., Filetti S., Damante G., Tell G. APE/Ref-1 is increased in nuclear fractions of human thyroid hyperfunctioning nodules. Mol. Cell. Endocrinol. 2002, 194:71-76.
15. Puppin C., D'Aurizio F., D'Elia A.V., Cesaratto L., Tell G., Russo D., Filetti S., Ferretti E., Tosi E., Mattei T., Pianta A., Pellizzari L., Damante G. Effects of histone acetylation on NIS promoter and expression of thyroid-specific transcription factors. Endocrinology 2005, 146:3967-3974.
16. Damante G., Russo D., Foti D., Grasso G., Filetti S. Effect of thyrotropin and cAMP on FRTL5 cell growth in a serum free medium. J. Endocrinol. Invest. 1990, 13:397-402.
17. Lee S.B., Xuan Nguyen T.L., Choi J.W., Lee K.H., Cho S.W., Liu Z., Ye K., Bae S.S., Ahn J.Y. Nuclear Akt interacts with B23/NPM and protects it from proteolytic cleavage, enhancing cell survival. Proc. Natl. Acad. Sci. USA 2008, 105:16584-16589.
18. Grisendi S., Bernardi R., Rossi M., Cheng K., Khandker L., Manova K., Pandolfi P.P. Role of nucleophosmin in embryonic development and tumorigenesis. Nature 2005, 437:147-153.
19. Lim M.J., Wang X.W. Nucleophosmin and human cancer. Cancer Detect. Prev. 2006, 30:481-490.
20. Kuo M.L., Den Besten W., Bertwistle D., Roussel M.F., Sherr C.J. N-terminal polyubiquitination and degradation of the Arf tumor suppressor. Genes Dev. 2004, 18:1862-1874.
21. Zhang Y. The ARF-B23 connection: implications for growth control and cancer treatment. Cell Cycle 2004, 3:259-262.
22. Li Z., Boone D., Hann S.R. Nucleophosmin interacts directly with c-Myc and controls c-Myc-indiced hyperproliferation and transformation. Proc. Natl. Acad. Sci. USA 2008, 105:18794-18799.
23. Boon K., Caron H.N., Van Asperen R., Valentijn L., Hermus M.C., van Sluis P., Roobeek I., Weis I., Voûte P.A., Schwab M., Versteeg R. N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO J. 2001, 20:1383-1393.
24. Shinohara M., Chung Y.J., Saji M., Ringel M.D. AKT in thyroid tumorigenesis and progression. Endocrinology 2007, 148:942-947.