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Volumn 59, Issue 12, 2011, Pages 1987-1995

Nitric oxide induces the expression of the monocarboxylate transporter MCT4 in cultured astrocytes by a cGMP-independent transcriptional activation

Author keywords

Energy metabolism; Glia; Lactate; MCT1; NO

Indexed keywords

CYCLIC GMP; GUANYLATE CYCLASE INHIBITOR; LACTIC ACID; MESSENGER RNA; MONOCARBOXYLATE TRANSPORTER 4; NITRIC OXIDE; NITRIC OXIDE DONOR; SMALL INTERFERING RNA;

EID: 80053566381     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.21240     Document Type: Article
Times cited : (21)

References (45)
  • 1
    • 0037107408 scopus 로고    scopus 로고
    • Dynamic imaging of free cytosolic ATP concentration during fuel sensing by rat hypothalamic neurones: Evidence for ATP-independent control of ATP-sensitive K(+) channels
    • Ainscow EK, Mirshamsi S, Tang T, Ashford ML, Rutter GA. 2002. Dynamic imaging of free cytosolic ATP concentration during fuel sensing by rat hypothalamic neurones: Evidence for ATP-independent control of ATP-sensitive K(+) channels. J Physiol 544: 429-445.
    • (2002) J Physiol , vol.544 , pp. 429-445
    • Ainscow, E.K.1    Mirshamsi, S.2    Tang, T.3    Ashford, M.L.4    Rutter, G.A.5
  • 2
    • 1342310736 scopus 로고    scopus 로고
    • Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway
    • Almeida A, Moncada S, Bolaños JP. 2004. Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway. Nat Cell Biol 6: 45-51.
    • (2004) Nat Cell Biol , vol.6 , pp. 45-51
    • Almeida, A.1    Moncada, S.2    Bolaños, J.P.3
  • 3
    • 31144464236 scopus 로고    scopus 로고
    • Nitric oxide release during evoked neuronal activity in cerebellum slices: detection with platinized carbon-fiber microelectrodes
    • Amatore C, Arbault S, Bouret Y, Cauli B, Guille M, Rancillac A, Rossier J. 2006. Nitric oxide release during evoked neuronal activity in cerebellum slices: detection with platinized carbon-fiber microelectrodes. Chem Phys Chem 7: 181-187.
    • (2006) Chem Phys Chem , vol.7 , pp. 181-187
    • Amatore, C.1    Arbault, S.2    Bouret, Y.3    Cauli, B.4    Guille, M.5    Rancillac, A.6    Rossier, J.7
  • 4
    • 78649353334 scopus 로고    scopus 로고
    • Physiologic role for "inducible" nitric oxide synthase: A new form of astrocytic-neuronal interface
    • Amitai Y. 2010. Physiologic role for "inducible" nitric oxide synthase: A new form of astrocytic-neuronal interface. Glia 58: 1775-1781.
    • (2010) Glia , vol.58 , pp. 1775-1781
    • Amitai, Y.1
  • 6
    • 33846910806 scopus 로고    scopus 로고
    • Is lactate food for neurons? Comparison of monocarboxylate transporter subtypes in brain and muscle
    • Bergersen LH. 2007. Is lactate food for neurons? Comparison of monocarboxylate transporter subtypes in brain and muscle. Neuroscience 145: 11-19.
    • (2007) Neuroscience , vol.145 , pp. 11-19
    • Bergersen, L.H.1
  • 7
    • 0035114149 scopus 로고    scopus 로고
    • A novel postsynaptic density protein: the monocarboxylate transporter MCT2 is co-localized with delta-glutamate receptors in postsynaptic densities of parallel fiber-Purkinje cell synapses
    • Bergersen L, Waerhaug O, Helm J, Thomas M, Laake P, Davies AJ, Wilson MC, Halestrap AP, Ottersen OP. 2001. A novel postsynaptic density protein: the monocarboxylate transporter MCT2 is co-localized with delta-glutamate receptors in postsynaptic densities of parallel fiber-Purkinje cell synapses. Exp Brain Res 136: 523-534.
    • (2001) Exp Brain Res , vol.136 , pp. 523-534
    • Bergersen, L.1    Waerhaug, O.2    Helm, J.3    Thomas, M.4    Laake, P.5    Davies, A.J.6    Wilson, M.C.7    Halestrap, A.P.8    Ottersen, O.P.9
  • 8
    • 0028145462 scopus 로고
    • Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes
    • Bolaños JP, Peuchen S, Heales SJ, Land JM, Clark JB. 1994. Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes. J Neurochem 63: 910-916.
    • (1994) J Neurochem , vol.63 , pp. 910-916
    • Bolaños, J.P.1    Peuchen, S.2    Heales, S.J.3    Land, J.M.4    Clark, J.B.5
  • 9
    • 33745872953 scopus 로고    scopus 로고
    • Modulation of astroglial energy metabolism by nitric oxide
    • Bolaños JP, Almeida A. 2006. Modulation of astroglial energy metabolism by nitric oxide. Antioxid Redox Signal 8: 955-965.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 955-965
    • Bolaños, J.P.1    Almeida, A.2
  • 11
    • 33748896023 scopus 로고    scopus 로고
    • Competition between glucose and lactate as oxidative energy substrates in both neurons and astrocytes: a comparative NMR study
    • Bouzier-Sore AK, Voisin P, Bouchaud V, Bezancon E, Franconi JM, Pellerin L. 2006. Competition between glucose and lactate as oxidative energy substrates in both neurons and astrocytes: a comparative NMR study. Eur J Neurosci 24: 1687-1694.
    • (2006) Eur J Neurosci , vol.24 , pp. 1687-1694
    • Bouzier-Sore, A.K.1    Voisin, P.2    Bouchaud, V.3    Bezancon, E.4    Franconi, J.M.5    Pellerin, L.6
  • 12
    • 41149111809 scopus 로고    scopus 로고
    • Regulation of transcription factors by nitric oxide in neurons and in neural-derived tumor cells
    • Contestabile A. 2008. Regulation of transcription factors by nitric oxide in neurons and in neural-derived tumor cells. Prog Neurobiol 84: 317-328.
    • (2008) Prog Neurobiol , vol.84 , pp. 317-328
    • Contestabile, A.1
  • 13
    • 0037963512 scopus 로고    scopus 로고
    • Cell-specific expression pattern of monocarboxylate transporters in astrocytes and neurons observed in different mouse brain cortical cell cultures
    • Debernardi R, Pierre K, Lengacher S, Magistretti PJ, Pellerin L. 2003. Cell-specific expression pattern of monocarboxylate transporters in astrocytes and neurons observed in different mouse brain cortical cell cultures. J Neurosci Res 73: 141-155.
    • (2003) J Neurosci Res , vol.73 , pp. 141-155
    • Debernardi, R.1    Pierre, K.2    Lengacher, S.3    Magistretti, P.J.4    Pellerin, L.5
  • 14
    • 0034663601 scopus 로고    scopus 로고
    • The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells
    • Dimmer KS, Friedrich B, Lang F, Deitmer JW, Bröer S. 2000. The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells. Biochem J 350: 219-227.
    • (2000) Biochem J , vol.350 , pp. 219-227
    • Dimmer, K.S.1    Friedrich, B.2    Lang, F.3    Deitmer, J.W.4    Bröer, S.5
  • 15
    • 45149088480 scopus 로고    scopus 로고
    • Concepts of neural nitric oxide-mediated transmission
    • Garthwaite J. 2008. Concepts of neural nitric oxide-mediated transmission. Eur J Neurosci 27: 2783-2802.
    • (2008) Eur J Neurosci , vol.27 , pp. 2783-2802
    • Garthwaite, J.1
  • 16
    • 0030837750 scopus 로고    scopus 로고
    • Expression of monocarboxylate transporter MCT1 by brain endothelium and glia in adult and suckling rats
    • Gerhart DZ, Enerson BE, Zhdankina OY, Leino RL, Drewes LR. 1997. Expression of monocarboxylate transporter MCT1 by brain endothelium and glia in adult and suckling rats. Am J Physiol 273: E207-E213.
    • (1997) Am J Physiol , vol.273
    • Gerhart, D.Z.1    Enerson, B.E.2    Zhdankina, O.Y.3    Leino, R.L.4    Drewes, L.R.5
  • 17
    • 1242340302 scopus 로고    scopus 로고
    • The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond
    • Halestrap AP, Meredith D. 2004. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflugers Arch 447: 619-628.
    • (2004) Pflugers Arch , vol.447 , pp. 619-628
    • Halestrap, A.P.1    Meredith, D.2
  • 18
    • 0034041755 scopus 로고    scopus 로고
    • Monocarboxylic acid transporters, MCT1 and MCT2, in cortical astrocytes in vitro and in vivo
    • Hanu R, McKenna M, O'Neill A, Resneck WG, Bloch RJ. 2000. Monocarboxylic acid transporters, MCT1 and MCT2, in cortical astrocytes in vitro and in vivo Am J Physiol 278: C921-C930.
    • (2000) Am J Physiol , vol.278
    • Hanu, R.1    McKenna, M.2    O'Neill, A.3    Resneck, W.G.4    Bloch, R.J.5
  • 19
    • 67349249403 scopus 로고    scopus 로고
    • The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1
    • Herrero-Mendez A, Almeida A, Fernández E, Maestre C, Moncada S, Bolaños JP. 2009. The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1. Nat Cell Biol 11: 747-752.
    • (2009) Nat Cell Biol , vol.11 , pp. 747-752
    • Herrero-Mendez, A.1    Almeida, A.2    Fernández, E.3    Maestre, C.4    Moncada, S.5    Bolaños, J.P.6
  • 20
    • 33751100379 scopus 로고    scopus 로고
    • Tonic and phasic nitric oxide signals in hippocampal long-term potentiation
    • Hopper RA, Garthwaite J. 2006. Tonic and phasic nitric oxide signals in hippocampal long-term potentiation. J Neurosci 26: 11513-11521.
    • (2006) J Neurosci , vol.26 , pp. 11513-11521
    • Hopper, R.A.1    Garthwaite, J.2
  • 21
    • 0037446874 scopus 로고    scopus 로고
    • Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo
    • Itoh Y, Esaki T, Shimoji K, Cook M, Law MJ, Kaufman E, Sokoloff L. 2003. Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo. Proc Natl Acad Sci USA 100: 4879-4884.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4879-4884
    • Itoh, Y.1    Esaki, T.2    Shimoji, K.3    Cook, M.4    Law, M.J.5    Kaufman, E.6    Sokoloff, L.7
  • 22
    • 79958122800 scopus 로고    scopus 로고
    • Real-time evaluation of nitric oxide (NO) levels in cortical and hippocampal areas with a nanopore-based electrochemical NO sensor
    • Jo A, Do H, Jhon GJ, Suh M, Lee Y. 2011. Real-time evaluation of nitric oxide (NO) levels in cortical and hippocampal areas with a nanopore-based electrochemical NO sensor. Neurosci Lett 498: 22-25.
    • (2011) Neurosci Lett , vol.498 , pp. 22-25
    • Jo, A.1    Do, H.2    Jhon, G.J.3    Suh, M.4    Lee, Y.5
  • 23
  • 24
    • 0033548527 scopus 로고    scopus 로고
    • Monocarboxylate transporter (MCT1) abundance in brains of suckling and adult rats: A quantitative electron microscopic immunogold study
    • Leino RL, Gerhart DZ, Drewes LR. 1999. Monocarboxylate transporter (MCT1) abundance in brains of suckling and adult rats: A quantitative electron microscopic immunogold study. Brain Res 113: 47-54.
    • (1999) Brain Res , vol.113 , pp. 47-54
    • Leino, R.L.1    Gerhart, D.Z.2    Drewes, L.R.3
  • 25
    • 0030038635 scopus 로고    scopus 로고
    • NMDA receptor-mediated cGMP synthesis in primary cultures of mouse cerebellar granule cells appears to involve neuron-astrocyte communication with NO operating as the intercellular messenger
    • Malcolm C, Grieve A, Ritchie L, Schousboe A, Griffiths R. 1996. NMDA receptor-mediated cGMP synthesis in primary cultures of mouse cerebellar granule cells appears to involve neuron-astrocyte communication with NO operating as the intercellular messenger. J Neurosci Res 45: 129-142.
    • (1996) J Neurosci Res , vol.45 , pp. 129-142
    • Malcolm, C.1    Grieve, A.2    Ritchie, L.3    Schousboe, A.4    Griffiths, R.5
  • 26
    • 0034525940 scopus 로고    scopus 로고
    • Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle
    • Manning Fox JE, Meredith D, Halestrap AP. 2000. Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle. J Physiol 529: 285-293.
    • (2000) J Physiol , vol.529 , pp. 285-293
    • Manning Fox, J.E.1    Meredith, D.2    Halestrap, A.P.3
  • 27
    • 0042469448 scopus 로고    scopus 로고
    • Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases
    • Metzen E, Zhou J, Jelkmann W, Fandrey J, Brüne B. 2003. Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases. Mol Biol Cell 14: 3470-3481.
    • (2003) Mol Biol Cell , vol.14 , pp. 3470-3481
    • Metzen, E.1    Zhou, J.2    Jelkmann, W.3    Fandrey, J.4    Brüne, B.5
  • 28
    • 33745039466 scopus 로고    scopus 로고
    • Nitric oxide, cell bioenergetics and neurodegeneration
    • Moncada S, Bolaños JP. 2006. Nitric oxide, cell bioenergetics and neurodegeneration. J Neurochem 97: 1676-1689.
    • (2006) J Neurochem , vol.97 , pp. 1676-1689
    • Moncada, S.1    Bolaños, J.P.2
  • 30
    • 2442664117 scopus 로고    scopus 로고
    • Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase
    • Palacios-Callender M, Quintero M, Hollis VS, Springett RJ, Moncada S. 2004. Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase. Proc Natl Acad Sci USA 101: 7630-7635.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 7630-7635
    • Palacios-Callender, M.1    Quintero, M.2    Hollis, V.S.3    Springett, R.J.4    Moncada, S.5
  • 31
    • 0037727888 scopus 로고    scopus 로고
    • Lactate as a pivotal element in neuron-glia metabolic cooperation
    • Pellerin L. 2003. Lactate as a pivotal element in neuron-glia metabolic cooperation. Neurochem Int 43: 331-338.
    • (2003) Neurochem Int , vol.43 , pp. 331-338
    • Pellerin, L.1
  • 32
    • 0031775697 scopus 로고    scopus 로고
    • Monocarboxylate transporter MCT1 is located in the apical membrane and MCT3 in the basal membrane of rat RPE
    • Philp NJ, Yoon H, Grollman EF. 1998. Monocarboxylate transporter MCT1 is located in the apical membrane and MCT3 in the basal membrane of rat RPE. Am J Physiol 274: R1824-R1828.
    • (1998) Am J Physiol , vol.274
    • Philp, N.J.1    Yoon, H.2    Grollman, E.F.3
  • 33
    • 12244262261 scopus 로고    scopus 로고
    • Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain
    • Pellerin L, Bergersen LH, Halestrap AP, Pierre K. 2005. Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain. J Neurosci Res 79: 55-64.
    • (2005) J Neurosci Res , vol.79 , pp. 55-64
    • Pellerin, L.1    Bergersen, L.H.2    Halestrap, A.P.3    Pierre, K.4
  • 34
    • 0036254152 scopus 로고    scopus 로고
    • MCT2 is a major neuronal monocarboxylate transporter in the adult mouse brain
    • Pierre K, Magistretti PJ, Pellerin L. 2002. MCT2 is a major neuronal monocarboxylate transporter in the adult mouse brain. J Cereb Blood Flow Metab 22: 586-595.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 586-595
    • Pierre, K.1    Magistretti, P.J.2    Pellerin, L.3
  • 35
    • 21344444566 scopus 로고    scopus 로고
    • Monocarboxylate transporters in the central nervous system: Distribution, regulation and function
    • Pierre K, Pellerin L. 2005. Monocarboxylate transporters in the central nervous system: Distribution, regulation and function. J Neurochem 94: 1-14.
    • (2005) J Neurochem , vol.94 , pp. 1-14
    • Pierre, K.1    Pellerin, L.2
  • 36
    • 0242485280 scopus 로고    scopus 로고
    • Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain
    • Rafiki A, Boulland JL, Halestrap AP, Ottersen OP, Bergersen L. 2003. Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain. Neuroscience 122: 677-688.
    • (2003) Neuroscience , vol.122 , pp. 677-688
    • Rafiki, A.1    Boulland, J.L.2    Halestrap, A.P.3    Ottersen, O.P.4    Bergersen, L.5
  • 38
    • 0034790541 scopus 로고    scopus 로고
    • Oxidative stress induces proophanin FQ, proenkephalin gene expression in astrocytes through p38- and ERK-MAP kinases and NF-kB
    • Rosenberger J, Petrovics G, Buzas B. 2001. Oxidative stress induces proophanin FQ, proenkephalin gene expression in astrocytes through p38- and ERK-MAP kinases and NF-kB. J Neurochem 79: 35-44.
    • (2001) J Neurochem , vol.79 , pp. 35-44
    • Rosenberger, J.1    Petrovics, G.2    Buzas, B.3
  • 39
    • 0030867321 scopus 로고    scopus 로고
    • Nitric oxide: A spatial second messenger
    • Schulman H. 1997. Nitric oxide: A spatial second messenger. Mol Psychiatry 2: 296-299.
    • (1997) Mol Psychiatry , vol.2 , pp. 296-299
    • Schulman, H.1
  • 40
    • 28444498930 scopus 로고    scopus 로고
    • Functional characteristics of H+ -dependent nicotinate transport in primary cultures of astrocytes from rat cerebral cortex
    • Shimada A, Nakagawa Y, Morishige H, Yamamoto A, Fujita T. 2006. Functional characteristics of H+ -dependent nicotinate transport in primary cultures of astrocytes from rat cerebral cortex. Neurosci Lett 392: 207-212.
    • (2006) Neurosci Lett , vol.392 , pp. 207-212
    • Shimada, A.1    Nakagawa, Y.2    Morishige, H.3    Yamamoto, A.4    Fujita, T.5
  • 41
    • 0026458243 scopus 로고
    • Vasoactive intestinal peptide and noradrenaline exert long-term control on glycogen levels in astrocytes: blockade by protein synthesis inhibition
    • Sorg O, Magistretti PJ. 1992. Vasoactive intestinal peptide and noradrenaline exert long-term control on glycogen levels in astrocytes: blockade by protein synthesis inhibition. J Neurosci 12: 4923-4931.
    • (1992) J Neurosci , vol.12 , pp. 4923-4931
    • Sorg, O.1    Magistretti, P.J.2
  • 42
    • 77956318603 scopus 로고    scopus 로고
    • Nitric oxide signaling in brain function, dysfunction, and dementia
    • Steinert JR, Chernova T, Forsythe ID. 2010. Nitric oxide signaling in brain function, dysfunction, and dementia. Neuroscientist 16: 435-452.
    • (2010) Neuroscientist , vol.16 , pp. 435-452
    • Steinert, J.R.1    Chernova, T.2    Forsythe, I.D.3
  • 43
    • 68149105927 scopus 로고    scopus 로고
    • Protons make tumor cells move like clockwork
    • Stock C, Schwab A. 2009. Protons make tumor cells move like clockwork. Pflugers Arch 458: 981-992.
    • (2009) Pflugers Arch , vol.458 , pp. 981-992
    • Stock, C.1    Schwab, A.2
  • 44
    • 63849086007 scopus 로고    scopus 로고
    • Cerebral blood flow regulation by nitric oxide: Recent advances
    • Toda N, Ayajiki K, Okamura T. 2009. Cerebral blood flow regulation by nitric oxide: Recent advances. Pharmacol Rev 61: 62-97.
    • (2009) Pharmacol Rev , vol.61 , pp. 62-97
    • Toda, N.1    Ayajiki, K.2    Okamura, T.3
  • 45
    • 33646917296 scopus 로고    scopus 로고
    • The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism
    • Ullah MS, Davies AJ, Halestrap AP. 2006. The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism. J Biol Chem 281: 9030-9037.
    • (2006) J Biol Chem , vol.281 , pp. 9030-9037
    • Ullah, M.S.1    Davies, A.J.2    Halestrap, A.P.3


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