Mite serine protease activates protease-activated receptor-2 and induces cytokine release in human keratinocytes

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 64, Issue 9, 2009, Pages 1366-1374

  Kato, T ^a   Takai, T ^a   Fujimura, T ^a   Matsuoka, H ^b   Ogawa, T ^a   Murayama, K ^a   Ishii, A ^b   Ikeda, S ^a   Okumura, K ^a   Ogawa, H ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Atopic dermatitis; Cysteine protease; House dust mite; Keratinocyte; Proinflammatory cytokine response; Protease activated receptor 2; Serine protease

Indexed keywords

CALCIUM ION; CYSTEINE PROTEINASE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 8; MESSENGER RNA; PROTEINASE ACTIVATED RECEPTOR 2; SERINE PROTEINASE; TRYPSIN;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; ANTIGENS, DERMATOPHAGOIDES; CALCIUM; CELLS, CULTURED; DERMATITIS, ATOPIC; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-8; KERATINOCYTES; PEPTIDES; PYROGLYPHIDAE; RECEPTOR, PAR-2; RECOMBINANT PROTEINS; RNA, MESSENGER; SERINE PROTEASES;

EID: 68949207370     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2009.02023.x     Document Type: Article

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