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Volumn 3, Issue 1, 2011, Pages

Amyotrophic lateral sclerosis: New genes, new models, and new mechanisms

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; APOLIPOPROTEIN E; COPPER ZINC SUPEROXIDE DISMUTASE; GLYCINE; POLYGLUTAMINE; RNA BINDING PROTEIN; TAR DNA BINDING PROTEIN; VALOSIN CONTAINING PROTEIN;

EID: 80053537470     PISSN: 17404118     EISSN: 1757594X     Source Type: Journal    
DOI: 10.3410/B3-18     Document Type: Review
Times cited : (8)

References (56)
  • 1
    • 70350075024 scopus 로고    scopus 로고
    • Genetics of motor neuron disorders: New insights into pathogenic mechanisms
    • Dion PA, Daoud H, Rouleau GA: Genetics of motor neuron disorders: new insights into pathogenic mechanisms. Nat Rev Genet 2009, 10:769-82.
    • (2009) Nat Rev Genet , vol.10 , pp. 769-782
    • Dion, P.A.1    Daoud, H.2    Rouleau, G.A.3
  • 2
    • 33749056809 scopus 로고    scopus 로고
    • ALS: A disease of motor neurons and their nonneuronal neighbors
    • Boillee S, Vande Velde C, Cleveland DW: ALS: A disease of motor neurons and their nonneuronal neighbors. Neuron 2006, 52:1-21.
    • (2006) Neuron , vol.52 , pp. 1-21
    • Boillee, S.1    Vande Velde, C.2    Cleveland, D.W.3
  • 3
    • 0029977337 scopus 로고    scopus 로고
    • Doseranging study of riluzole in amyotrophic lateral sclerosis
    • Amyotrophic Lateral Sclerosis/Riluzole Study Group II. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • Lacomblez L, Bensimon G, Leigh PN, Guillet P, Meininger V: Doseranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II. Lancet 1996, 347:1425-31. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • (1996) Lancet , vol.347 , pp. 1425-1431
    • Lacomblez, L.1    Bensimon, G.2    Leigh, P.N.3    Guillet, P.4    Meininger, V.5
  • 4
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis
    • ALS/Riluzole Study Group. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • Bensimon G, Lacomblez L, Meininger V: A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. N Engl J Med 1994, 330:585-91. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • (1994) N Engl J Med , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 5
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A, Donaldson D, Goto J, O'Regan JP, Deng HX: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993, 362:59-62. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • (1993) Nature , vol.362 , pp. 59-62
    • Rosen, D.R.1    Siddique, T.2    Patterson, D.3    Figlewicz, D.A.4    Sapp, P.5    Hentati, A.6    Donaldson, D.7    Goto, J.8    O'Regan, J.P.9    Deng, H.X.10
  • 6
    • 74049164709 scopus 로고    scopus 로고
    • Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
    • F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • Ilieva H, Polymenidou M, Cleveland DW: Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond. J Cell Biol 2009, 187:761-72. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • (2009) J Cell Biol , vol.187 , pp. 761-772
    • Ilieva, H.1    Polymenidou, M.2    Cleveland, D.W.3
  • 7
    • 62149141328 scopus 로고    scopus 로고
    • Rethinking ALS: The FUS about TDP-43
    • F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • Lagier-Tourenne C and Cleveland DW: Rethinking ALS: the FUS about TDP-43. Cell 2009, 136:1001-4. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • (2009) Cell , vol.136 , pp. 1001-1004
    • Lagier-Tourenne, C.1    Cleveland, D.W.2
  • 10
    • 80051570216 scopus 로고    scopus 로고
    • Screening for OPTN mutations in amyotrophic lateral sclerosis in a mainly Caucasian population
    • F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • Sugihara K, Maruyama H, Kamada M, Morino H, Kawakami H: Screening for OPTN mutations in amyotrophic lateral sclerosis in a mainly Caucasian population. Neurobiol Aging 2011, 32:1923.e9-10. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • (2011) Neurobiol Aging , vol.32
    • Sugihara, K.1    Maruyama, H.2    Kamada, M.3    Morino, H.4    Kawakami, H.5
  • 19
    • 76149120427 scopus 로고    scopus 로고
    • Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery
    • F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • Freibaum BD, Chitta RK, High AA, Taylor JP: Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. J Proteome Res 2010, 9:1104-20. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • (2010) J Proteome Res , vol.9 , pp. 1104-1120
    • Freibaum, B.D.1    Chitta, R.K.2    High, A.A.3    Taylor, J.P.4
  • 21
    • 70350135049 scopus 로고    scopus 로고
    • TDP-43 is recruited to stress granules in conditions of oxidative insult
    • F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • Colombrita C, Zennaro E, Fallini C, Weber M, Sommacal A, Buratti E, Silani V, Ratti A: TDP-43 is recruited to stress granules in conditions of oxidative insult. J Neurochem 2009, 111:1051-61. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • (2009) J Neurochem , vol.111 , pp. 1051-1061
    • Colombrita, C.1    Zennaro, E.2    Fallini, C.3    Weber, M.4    Sommacal, A.5    Buratti, E.6    Silani, V.7    Ratti, A.8
  • 23
    • 77955792022 scopus 로고    scopus 로고
    • ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
    • F1000 Factor 7 Evaluated by Yuh Min Chook 09 Nov 2010, Guy Rouleau 17 Aug 2011
    • Dormann D, Rodde R, Edbauer D, Bentmann E, Fischer I, Hruscha A, Than ME, Mackenzie IR, Capell A, Schmid B, Neumann M, Haass C: ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import. EMBO J 2010, 29:2841-57. F1000 Factor 7 Evaluated by Yuh Min Chook 09 Nov 2010, Guy Rouleau 17 Aug 2011
    • (2010) EMBO J , vol.29 , pp. 2841-2857
    • Dormann, D.1    Rodde, R.2    Edbauer, D.3    Bentmann, E.4    Fischer, I.5    Hruscha, A.6    Than, M.E.7    Mackenzie, I.R.8    Capell, A.9    Schmid, B.10    Neumann, M.11    Haass, C.12
  • 24
    • 80053646130 scopus 로고    scopus 로고
    • Nuclear localization sequence of FUS and induction of stress granules by ALS mutants
    • [Epub ahead of print]. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • Gal J, Zhang J, Kwinter DM, Zhai J, Jia H, Jia J, Zhu H: Nuclear localization sequence of FUS and induction of stress granules by ALS mutants. Neurobiol Aging 2010, [Epub ahead of print]. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • (2010) Neurobiol Aging
    • Gal, J.1    Zhang, J.2    Kwinter, D.M.3    Zhai, J.4    Jia, H.5    Jia, J.6    Zhu, H.7
  • 25
    • 58049221032 scopus 로고    scopus 로고
    • Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: Implications for TDP-43 in the physiological response to neuronal injury
    • F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • Moisse K, Volkening K, Leystra-Lantz C, Welch I, Hill T, Strong MJ: Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury. Brain Res 2009, 1249:202-11. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • (2009) Brain Res , vol.1249 , pp. 202-211
    • Moisse, K.1    Volkening, K.2    Leystra-Lantz, C.3    Welch, I.4    Hill, T.5    Strong, M.J.6
  • 36
    • 1842483843 scopus 로고    scopus 로고
    • Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein
    • DOI 10.1038/ng1332
    • Watts GD, Wymer J, Kovach MJ, Mehta SG, Mumm S, Darvish D, Pestronk A, Whyte MP, Kimonis VE: Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein. Nat Genet 2004, 36:377-81. (Pubitemid 38437260)
    • (2004) Nature Genetics , vol.36 , Issue.4 , pp. 377-381
    • Watts, G.D.J.1    Wymer, J.2    Kovach, M.J.3    Mehta, S.G.4    Mumm, S.5    Darvish, D.6    Pestronk, A.7    Whyte, M.P.8    Kimonis, V.E.9
  • 39
    • 0034326242 scopus 로고    scopus 로고
    • Cognitive change in motor neurone disease/amyotrophic lateral sclerosis (MND/ALS)
    • Neary D, Snowden JS, Mann DM: Cognitive change in motor neurone disease/amyotrophic lateral sclerosis (MND/ALS). J Neurol Sci 2000, 180:15-20.
    • (2000) J Neurol Sci , vol.180 , pp. 15-20
    • Neary, D.1    Snowden, J.S.2    Mann, D.M.3
  • 43
    • 3242703300 scopus 로고    scopus 로고
    • Amyotrophic Lateral Sclerosis-Associated SOD1 Mutant Proteins Bind and Aggregate with Bcl-2 in Spinal Cord Mitochondria
    • F1000 Factor 7 Evaluated by Albert La Spada 17 Nov 2004, Guy Rouleau 17 Aug 2011
    • Pasinelli P, Belford ME, Lennon N, Bacskai BJ, Hyman BT, Trotti D, Brown RH, Jr.: Amyotrophic Lateral Sclerosis-Associated SOD1 Mutant Proteins Bind and Aggregate with Bcl-2 in Spinal Cord Mitochondria. Neuron 2004, 43:19-30. F1000 Factor 7 Evaluated by Albert La Spada 17 Nov 2004, Guy Rouleau 17 Aug 2011
    • (2004) Neuron , vol.43 , pp. 19-30
    • Pasinelli, P.1    Belford, M.E.2    Lennon, N.3    Bacskai, B.J.4    Hyman, B.T.5    Trotti, D.6    Brown Jr., R.H.7
  • 45
    • 34249980373 scopus 로고    scopus 로고
    • An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS
    • F1000 Factor 8 Evaluated by Nereo Bresolin 20 Jun 2007, Guy Rouleau 17 Aug 2011
    • Rakhit R, Robertson J, Vande Velde C, Horne P, Ruth DM, Griffin J, Cleveland DW, Cashman NR, Chakrabartty A: An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS. Nat Med 2007, 13:754-9. F1000 Factor 8 Evaluated by Nereo Bresolin 20 Jun 2007, Guy Rouleau 17 Aug 2011
    • (2007) Nat Med , vol.13 , pp. 754-759
    • Rakhit, R.1    Robertson, J.2    Vande Velde, C.3    Horne, P.4    Ruth, D.M.5    Griffin, J.6    Cleveland, D.W.7    Cashman, N.R.8    Chakrabartty, A.9
  • 46
    • 77951924183 scopus 로고    scopus 로고
    • Intracerebroventricular infusion of monoclonal antibody or its derived Fab fragment against misfolded forms of SOD1 mutant delays mortality in a mouse model of ALS
    • F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • Gros-Louis F, Soucy G, Lariviere R, Julien JP: Intracerebroventricular infusion of monoclonal antibody or its derived Fab fragment against misfolded forms of SOD1 mutant delays mortality in a mouse model of ALS. J Neurochem 2010, 113:1188-99. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • (2010) J Neurochem , vol.113 , pp. 1188-1199
    • Gros-Louis, F.1    Soucy, G.2    Lariviere, R.3    Julien, J.P.4
  • 48
    • 77955961922 scopus 로고    scopus 로고
    • Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS
    • F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • Israelson A, Arbel N, Da Cruz S, Ilieva H, Yamanaka K, Shoshan- Barmatz V, Cleveland DW: Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS. Neuron 2010, 67:575-87. F1000 Factor 6 Evaluated by Guy Rouleau 17 Aug 2011
    • (2010) Neuron , vol.67 , pp. 575-587
    • Israelson, A.1    Arbel, N.2    Da Cruz, S.3    Ilieva, H.4    Yamanaka, K.5    Shoshan-Barmatz, V.6    Cleveland, D.W.7
  • 53
    • 34250177650 scopus 로고    scopus 로고
    • Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation
    • DOI 10.1111/j.1471-4159.2007.04531.x
    • Ezzi SA, Urushitani M, Julien JP: Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation. J Neurochem 2007, 102:170-8. (Pubitemid 46906269)
    • (2007) Journal of Neurochemistry , vol.102 , Issue.1 , pp. 170-178
    • Ezzi, S.A.1    Urushitani, M.2    Julien, J.-P.3
  • 54
    • 79951754463 scopus 로고    scopus 로고
    • Effect of genetic background on phenotype variability in transgenic mouse models of amyotrophic lateral sclerosis: A window of opportunity in the search for genetic modifiers
    • Heiman-Patterson TD, Sher RB, Blankenhorn EA, Alexander G, Deitch JS, Kunst CB, Maragakis N, Cox G: Effect of genetic background on phenotype variability in transgenic mouse models of amyotrophic lateral sclerosis: a window of opportunity in the search for genetic modifiers. Amyotroph Lateral Scler 2011, 12:79-86.
    • (2011) Amyotroph Lateral Scler , vol.12 , pp. 79-86
    • Heiman-Patterson, T.D.1    Sher, R.B.2    Blankenhorn, E.A.3    Alexander, G.4    Deitch, J.S.5    Kunst, C.B.6    Maragakis, N.7    Cox, G.8
  • 56
    • 79954608945 scopus 로고    scopus 로고
    • Emerging targets and treatments in amyotrophic lateral sclerosis
    • Zinman L and Cudkowicz M: Emerging targets and treatments in amyotrophic lateral sclerosis. Lancet Neurol 2011, 10:481-90.
    • (2011) Lancet Neurol , vol.10 , pp. 481-490
    • Zinman, L.1    Cudkowicz, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.