The correlation between multidomain enzymes and multiple activation mechanisms- the case of phospholipase Cβ and its membrane interactions

Biochimica et Biophysica Acta - Biomembranes

Volumn 1808, Issue 12, 2011, Pages 2940-2947

  Weinstein, Harel ^a   Scarlata, Suzanne ^b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Interdomain movement; Phospholipase C; Protein activation; Protein domains; Protein membrane interactions

Indexed keywords

BACTERIAL ENZYME; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C BETA; PHOSPHOLIPASE C BETA1; PHOSPHOLIPASE C BETA2; PHOSPHOLIPASE C BETA3; PHOSPHOLIPASE C DELTA; PHOSPHOLIPASE C DELTA1; RAC1 PROTEIN;

CATALYSIS; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; REVIEW;

AMINO ACID SEQUENCE; BIOCATALYSIS; CELL MEMBRANE; ENZYME ACTIVATION; HYDROLYSIS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASE C BETA;

EID: 80053456720     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2011.08.028     Document Type: Review

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