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Volumn 7, Issue 9, 2011, Pages

Exploiting and subverting tor signaling in the pathogenesis of fungi, parasites, and viruses

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; ALS1 PROTEIN; ALS3 PROTEIN; GROWTH FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HWP1; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERFERON; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MDS3 PROTEIN; PROTEIN KINASE B; RAPAMYCIN; RHEB PROTEIN; TARGET OF RAPAMYCIN KINASE; TORIN1; UL38 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 80053438567     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002269     Document Type: Article
Times cited : (17)

References (28)
  • 1
    • 0025776523 scopus 로고
    • Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast
    • Heitman J, Movva NR, Hall MN, (1991) Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science 253: 905-909.
    • (1991) Science , vol.253 , pp. 905-909
    • Heitman, J.1    Movva, N.R.2    Hall, M.N.3
  • 2
    • 77956886751 scopus 로고    scopus 로고
    • Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom
    • Shertz CA, Bastidas RJ, Li W, Heitman J, Cardenas ME, (2010) Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom. BMC Genomics 11: 510.
    • (2010) BMC Genomics , vol.11 , pp. 510
    • Shertz, C.A.1    Bastidas, R.J.2    Li, W.3    Heitman, J.4    Cardenas, M.E.5
  • 3
    • 77955391772 scopus 로고    scopus 로고
    • Expansion of the target of rapamycin (TOR) kinase family and function in Leishmania shows that TOR3 is required for acidocalcisome biogenesis and animal infectivity
    • Madeira da Silva L, Beverley SM, (2010) Expansion of the target of rapamycin (TOR) kinase family and function in Leishmania shows that TOR3 is required for acidocalcisome biogenesis and animal infectivity. Proc Natl Acad Sci U S A 107: 11965-11970.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 11965-11970
    • Madeira da Silva, L.1    Beverley, S.M.2
  • 4
    • 55749100531 scopus 로고    scopus 로고
    • Rapamycin inhibits trypanosome cell growth by preventing TOR complex 2 formation
    • Barquilla A, Crespo JL, Navarro M, (2008) Rapamycin inhibits trypanosome cell growth by preventing TOR complex 2 formation. Proc Natl Acad Sci U S A 105: 14579-14584.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 14579-14584
    • Barquilla, A.1    Crespo, J.L.2    Navarro, M.3
  • 5
    • 33646538482 scopus 로고    scopus 로고
    • The TOR signalling network from yeast to man
    • De Virgilio C, Loewith R, (2006) The TOR signalling network from yeast to man. Int J Biochem Cell Biol 38: 1476-1481.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 1476-1481
    • De Virgilio, C.1    Loewith, R.2
  • 6
    • 0036753494 scopus 로고    scopus 로고
    • Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
    • Loewith R, Jacinto E, Wullschleger S, Lorberg A, Crespo JL, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10: 457-468.
    • (2002) Mol Cell , vol.10 , pp. 457-468
    • Loewith, R.1    Jacinto, E.2    Wullschleger, S.3    Lorberg, A.4    Crespo, J.L.5
  • 7
    • 61449094788 scopus 로고    scopus 로고
    • The protein kinase Tor1 regulates adhesin gene expression in Candida albicans
    • doi: 10.1371/journal.ppat.1000294
    • Bastidas RJ, Heitman J, Cardenas ME, (2009) The protein kinase Tor1 regulates adhesin gene expression in Candida albicans. PLoS Pathog 5: e1000294 doi:10.1371/journal.ppat.1000294.
    • (2009) PLoS Pathog , vol.5
    • Bastidas, R.J.1    Heitman, J.2    Cardenas, M.E.3
  • 8
    • 39749164061 scopus 로고    scopus 로고
    • Discovering the secrets of the Candida albicans agglutinin-like sequence (ALS) gene family-a sticky pursuit
    • Hoyer LL, Green CB, Oh SH, Zhao X, (2008) Discovering the secrets of the Candida albicans agglutinin-like sequence (ALS) gene family-a sticky pursuit. Med Mycol 46: 1-15.
    • (2008) Med Mycol , vol.46 , pp. 1-15
    • Hoyer, L.L.1    Green, C.B.2    Oh, S.H.3    Zhao, X.4
  • 9
    • 0036961514 scopus 로고    scopus 로고
    • Candida albicans Mds3p, a conserved regulator of pH responses and virulence identified through insertional mutagenesis
    • Davis DA, Bruno VM, Loza L, Filler SG, Mitchell AP, (2002) Candida albicans Mds3p, a conserved regulator of pH responses and virulence identified through insertional mutagenesis. Genetics 162: 1573-1581.
    • (2002) Genetics , vol.162 , pp. 1573-1581
    • Davis, D.A.1    Bruno, V.M.2    Loza, L.3    Filler, S.G.4    Mitchell, A.P.5
  • 11
    • 77954364299 scopus 로고    scopus 로고
    • Mds3 regulates morphogenesis in Candida albicans through the TOR pathway
    • Zacchi LF, Gomez-Raja J, Davis DA, (2010) Mds3 regulates morphogenesis in Candida albicans through the TOR pathway. Mol Cell Biol 30: 3695-3710.
    • (2010) Mol Cell Biol , vol.30 , pp. 3695-3710
    • Zacchi, L.F.1    Gomez-Raja, J.2    Davis, D.A.3
  • 12
    • 0034521581 scopus 로고    scopus 로고
    • Differentiation of Trypanosoma cruzi epimastigotes: metacyclogenesis and adhesion to substrate are triggered by nutritional stress
    • Figueiredo RC, Rosa DS, Soares MJ, (2000) Differentiation of Trypanosoma cruzi epimastigotes: metacyclogenesis and adhesion to substrate are triggered by nutritional stress. J Parasitol 86: 1213-1218.
    • (2000) J Parasitol , vol.86 , pp. 1213-1218
    • Figueiredo, R.C.1    Rosa, D.S.2    Soares, M.J.3
  • 13
    • 36549074152 scopus 로고    scopus 로고
    • The cell biology of Trypanosoma brucei differentiation
    • Fenn K, Matthews KR, (2007) The cell biology of Trypanosoma brucei differentiation. Curr Opin Microbiol 10: 539-546.
    • (2007) Curr Opin Microbiol , vol.10 , pp. 539-546
    • Fenn, K.1    Matthews, K.R.2
  • 14
    • 61649084207 scopus 로고    scopus 로고
    • Trypanosome TOR as a major regulator of cell growth and autophagy
    • Barquilla A, Navarro M, (2009) Trypanosome TOR as a major regulator of cell growth and autophagy. Autophagy 5: 256-258.
    • (2009) Autophagy , vol.5 , pp. 256-258
    • Barquilla, A.1    Navarro, M.2
  • 15
    • 62449119294 scopus 로고    scopus 로고
    • Trypanosome TOR complex 2 functions in cytokinesis
    • Barquilla A, Navarro M, (2009) Trypanosome TOR complex 2 functions in cytokinesis. Cell Cycle 8: 697-699.
    • (2009) Cell Cycle , vol.8 , pp. 697-699
    • Barquilla, A.1    Navarro, M.2
  • 16
    • 52549127241 scopus 로고    scopus 로고
    • Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway
    • Cao W, Manicassamy S, Tang H, Kasturi SP, Pirani A, et al. (2008) Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway. Nat Immunol 9: 1157-1164.
    • (2008) Nat Immunol , vol.9 , pp. 1157-1164
    • Cao, W.1    Manicassamy, S.2    Tang, H.3    Kasturi, S.P.4    Pirani, A.5
  • 17
    • 9644268181 scopus 로고    scopus 로고
    • The role of type I interferons in non-viral infections
    • Bogdan C, Mattner J, Schleicher U, (2004) The role of type I interferons in non-viral infections. Immunol Rev 202: 33-48.
    • (2004) Immunol Rev , vol.202 , pp. 33-48
    • Bogdan, C.1    Mattner, J.2    Schleicher, U.3
  • 18
    • 79955054747 scopus 로고    scopus 로고
    • Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection
    • Jaramillo M, Gomez MA, Larsson O, Shio MT, Topisirovic I, et al. (2011) Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection. Cell Host Microbe 9: 331-341.
    • (2011) Cell Host Microbe , vol.9 , pp. 331-341
    • Jaramillo, M.1    Gomez, M.A.2    Larsson, O.3    Shio, M.T.4    Topisirovic, I.5
  • 20
    • 78649884803 scopus 로고    scopus 로고
    • Herpes Simplex Virus is Akt-ing in translational control
    • Norman KL, Sarnow P, (2010) Herpes Simplex Virus is Akt-ing in translational control. Genes Dev 24: 2583-2586.
    • (2010) Genes Dev , vol.24 , pp. 2583-2586
    • Norman, K.L.1    Sarnow, P.2
  • 21
    • 2342545519 scopus 로고    scopus 로고
    • Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
    • Fingar DC, Blenis J, (2004) Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 23: 3151-3171.
    • (2004) Oncogene , vol.23 , pp. 3151-3171
    • Fingar, D.C.1    Blenis, J.2
  • 22
    • 17444368316 scopus 로고    scopus 로고
    • Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A
    • Moody CA, Scott RS, Amirghahari N, Nathan CO, Young LS, et al. (2005) Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A. J Virol 79: 5499-5506.
    • (2005) J Virol , vol.79 , pp. 5499-5506
    • Moody, C.A.1    Scott, R.S.2    Amirghahari, N.3    Nathan, C.O.4    Young, L.S.5
  • 23
    • 33746832011 scopus 로고    scopus 로고
    • The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor
    • Sodhi A, Chaisuparat R, Hu J, Ramsdell AK, Manning BD, et al. (2006) The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor. Cancer Cell 10: 133-143.
    • (2006) Cancer Cell , vol.10 , pp. 133-143
    • Sodhi, A.1    Chaisuparat, R.2    Hu, J.3    Ramsdell, A.K.4    Manning, B.D.5
  • 24
    • 41849101685 scopus 로고    scopus 로고
    • Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex
    • Moorman NJ, Cristea IM, Terhune SS, Rout MP, Chait BT, et al. (2008) Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex. Cell Host Microbe 3: 253-262.
    • (2008) Cell Host Microbe , vol.3 , pp. 253-262
    • Moorman, N.J.1    Cristea, I.M.2    Terhune, S.S.3    Rout, M.P.4    Chait, B.T.5
  • 25
    • 78649857803 scopus 로고    scopus 로고
    • Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replication
    • Chuluunbaatar U, Roller R, Feldman ME, Brown S, Shokat KM, et al. (2010) Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replication. Genes Dev 24: 2627-2639.
    • (2010) Genes Dev , vol.24 , pp. 2627-2639
    • Chuluunbaatar, U.1    Roller, R.2    Feldman, M.E.3    Brown, S.4    Shokat, K.M.5
  • 26
    • 79952844950 scopus 로고    scopus 로고
    • The changing role of mTOR kinase in the maintenance of protein synthesis during human cytomegalovirus infection
    • Clippinger AJ, Maguire TG, Alwine JC, (2011) The changing role of mTOR kinase in the maintenance of protein synthesis during human cytomegalovirus infection. J Virol 85: 3930-3939.
    • (2011) J Virol , vol.85 , pp. 3930-3939
    • Clippinger, A.J.1    Maguire, T.G.2    Alwine, J.C.3
  • 27
    • 77951480815 scopus 로고    scopus 로고
    • Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication
    • Moorman NJ, Shenk T, (2010) Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication. J Virol 84: 5260-5269.
    • (2010) J Virol , vol.84 , pp. 5260-5269
    • Moorman, N.J.1    Shenk, T.2
  • 28
    • 77956180361 scopus 로고    scopus 로고
    • Autophagy and innate immunity: triggering, targeting and tuning
    • Sumpter R Jr, Levine B, (2010) Autophagy and innate immunity: triggering, targeting and tuning. Semin Cell Dev Biol 21: 699-711.
    • (2010) Semin Cell Dev Biol , vol.21 , pp. 699-711
    • Sumpter Jr., R.1    Levine, B.2


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