Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication

Journal of Virology

Volumn 84, Issue 10, 2010, Pages 5260-5269

  Moorman, Nathaniel J ^a   Shenk, Thomas ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 METHYLGUANOSINE; ENZYME INHIBITOR; MAMMALIAN TARGET OF RAPAMYCIN; MTORC1 ENZYME; RAPAMYCIN; TORIN1; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DRUG ACTIVITY; DRUG INHIBITION; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; HERPES VIRUS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARRIER PROTEINS; CELL LINE; CYTOMEGALOVIRUS; EUKARYOTIC INITIATION FACTOR-4F; FIBROBLASTS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MUROMEGALOVIRUS; PHOSPHOPROTEINS; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; SIROLIMUS; TRANSCRIPTION FACTORS; VIRUS REPLICATION;

CYTOMEGALOVIRUS; HERPESVIRIDAE; HUMAN HERPESVIRUS 5; MAIZE CHLOROTIC MOTTLE VIRUS; MURID HERPESVIRUS 1; MURINAE;

EID: 77951480815     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02733-09     Document Type: Article

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