-
1
-
-
45849085339
-
Cytochrome c: Functions beyond respiration
-
DOI 10.1038/nrm2434, PII NRM2434
-
Ow YP, Green DR, Hao Z, Mak TW. Cytochrome c: functions beyond respiration. Nat Rev Mol Cell Biol 2008; 9: 532-542. (Pubitemid 351881842)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.7
, pp. 532-542
-
-
Ow, Y.-L.P.1
Green, D.R.2
Hao, Z.3
Mak, T.W.4
-
2
-
-
34247345833
-
The apoptosome: Signalling platform of cell death
-
DOI 10.1038/nrm2153, PII NRM2153
-
Riedl SJ, Salvesen GS. The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol 2007; 8: 405-413. (Pubitemid 46643237)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.5
, pp. 405-413
-
-
Riedl, S.J.1
Salvesen, G.S.2
-
3
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
DOI 10.1126/science.1059108
-
Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 2001; 292: 727-730. (Pubitemid 32385543)
-
(2001)
Science
, vol.292
, Issue.5517
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.-X.2
Cheng, E.H.-Y.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
Macgregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
4
-
-
54949132875
-
Bcl-2 family proteins and cancer
-
Yip KW, Reed JC. Bcl-2 family proteins and cancer. Oncogene 2008; 27: 6398-6406.
-
(2008)
Oncogene
, vol.27
, pp. 6398-6406
-
-
Yip, K.W.1
Reed, J.C.2
-
5
-
-
77249169281
-
Turning enzymes on with small molecules
-
Zorn JA, Wells JA. Turning enzymes ON with small molecules. Nat Chem Biol 2010; 6: 179-188.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 179-188
-
-
Zorn, J.A.1
Wells, J.A.2
-
7
-
-
33748759801
-
Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy
-
DOI 10.1038/nchembio814, PII NCHEMBIO814
-
Putt KS, Chen GW, Pearson JM, Sandhorst JS, Hoagland MS, Kwon JT et al. Smallmolecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nat Chem Biol 2006; 2: 543-550. (Pubitemid 44413237)
-
(2006)
Nature Chemical Biology
, vol.2
, Issue.10
, pp. 543-550
-
-
Putt, K.S.1
Chen, G.W.2
Pearson, J.M.3
Sandhorst, J.S.4
Hoagland, M.S.5
Kwon, J.-T.6
Hwang, S.-K.7
Jin, H.8
Churchwell, M.I.9
Cho, M.-H.10
Doerge, D.R.11
Helferich, W.G.12
Hergenrother, P.J.13
-
8
-
-
63449138094
-
PAC-1 activates procaspase-3 in vitro through relief of zinc-mediated inhibition
-
Peterson QP, Goode DR, West DC, Ramsey KN, Lee JJ, Hergenrother PJ. PAC-1 activates procaspase-3 in vitro through relief of zinc-mediated inhibition. J Mol Biol 2009; 388: 144-158.
-
(2009)
J Mol Biol
, vol.388
, pp. 144-158
-
-
Peterson, Q.P.1
Goode, D.R.2
West, D.C.3
Ramsey, K.N.4
Lee, J.J.5
Hergenrother, P.J.6
-
9
-
-
70349433777
-
Procaspase-3 activation as an anti-cancer strategy: Structure-activity relationship of procaspaseactivating compound 1 (PAC-1) and its cellular co-localization with caspase-3
-
Peterson QP, Hsu DC, Goode DR, Novotny CJ, Totten RK, Hergenrother PJ. Procaspase-3 activation as an anti-cancer strategy: structure-activity relationship of procaspaseactivating compound 1 (PAC-1) and its cellular co-localization with caspase-3. J Med Chem 2009; 52: 5721-5731.
-
(2009)
J Med Chem
, vol.52
, pp. 5721-5731
-
-
Peterson, Q.P.1
Hsu, D.C.2
Goode, D.R.3
Novotny, C.J.4
Totten, R.K.5
Hergenrother, P.J.6
-
10
-
-
33847147664
-
Caspase cascade proceeds rapidly after cytochrome c release from mitochondria in tumor necrosis factor-induced cell death
-
DOI 10.1254/jphs.FP0060877
-
Kawai H, Suzuki T, Kobayashi T, Ishii-Watabe A, Sakurai H, Ohata H et al. Caspase cascade proceeds rapidly after cytochrome c release from mitochondria in tumor necrosis factor-alpha-induced cell death. J Pharmacol Sci 2007; 103: 159-167. (Pubitemid 46294647)
-
(2007)
Journal of Pharmacological Sciences
, vol.103
, Issue.2
, pp. 159-167
-
-
Kawai, H.1
Suzuki, T.2
Kobayashi, T.3
Ishii-Watabe, A.4
Sakurai, H.5
Ohata, H.6
Honda, K.7
Momose, K.8
Hayakawa, T.9
Kawanishi, T.10
-
11
-
-
32444434664
-
Caspases 3 and 7: Key mediators of mitochondrial events of apoptosis
-
DOI 10.1126/science.1115035
-
Lakhani SA, Masud A, Kuida K, Porter Jr GA, Booth CJ, Mehal WZ et al. Caspases 3 and 7: key mediators of mitochondrial events of apoptosis. Science 2006; 311: 847-851. (Pubitemid 43228848)
-
(2006)
Science
, vol.311
, Issue.5762
, pp. 847-851
-
-
Lakhani, S.A.1
Masud, A.2
Kuida, K.3
Porter Jr., G.A.4
Booth, C.J.5
Mehal, W.Z.6
Inayat, I.7
Flavell, R.A.8
-
12
-
-
0032472329
-
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
-
DOI 10.1093/emboj/17.1.37
-
Bossy-Wetzel E, Newmeyer DD, Green DR. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J 1998; 17: 37-49. (Pubitemid 28041046)
-
(1998)
EMBO Journal
, vol.17
, Issue.1
, pp. 37-49
-
-
Bossy-Wetzel, E.1
Newmeyer, D.D.2
Green, D.R.3
-
13
-
-
70349757833
-
Live to dead cell imaging
-
Tait SW, Bouchier-Hayes L, Oberst A, Connell S, Green DR. Live to dead cell imaging. Methods Mol Biol 2009; 559: 33-48.
-
(2009)
Methods Mol Biol
, vol.559
, pp. 33-48
-
-
Tait, S.W.1
Bouchier-Hayes, L.2
Oberst, A.3
Connell, S.4
Green, D.R.5
-
14
-
-
33846860595
-
A high throughput drug screen based on fluorescence resonance energy transfer (FRET) for anticancer activity of compounds from herbal medicine
-
DOI 10.1038/sj.bjp.0706988, PII 0706988
-
Tian H, Ip L, Luo H, Chang DC, Luo KQ. A high throughput drug screen based on fluorescence resonance energy transfer (FRET) for anticancer activity of compounds from herbal medicine. Br J Pharmacol 2007; 150: 321-334. (Pubitemid 46221041)
-
(2007)
British Journal of Pharmacology
, vol.150
, Issue.3
, pp. 321-334
-
-
Tian, H.1
Ip, L.2
Luo, H.3
Chang, D.C.4
Luo, K.Q.5
-
15
-
-
33745405779
-
Real-time detection of caspase-2 activation in a single living HeLa cell during cisplatin-induced apoptosis
-
Lin J, Zhang Z, Yang J, Zeng S, Liu BF, Luo Q. Real-time detection of caspase-2 activation in a single living HeLa cell during cisplatin-induced apoptosis. J Biomed Opt 2006; 11: 024011.
-
(2006)
J Biomed Opt
, vol.11
, pp. 024011
-
-
Lin, J.1
Zhang, Z.2
Yang, J.3
Zeng, S.4
Liu, B.F.5
Luo, Q.6
-
16
-
-
20244374710
-
Simultaneous real-time detection of initiator- and effector-caspase activation by double fluorescence resonance energy transfer analysis
-
DOI 10.1254/jphs.FP0040592
-
Kawai H, Suzuki T, Kobayashi T, Sakurai H, Ohata H, Honda K et al. Simultaneous realtime detection of initiator-and effector-caspase activation by double fluorescence resonance energy transfer analysis. J Pharmacol Sci 2005; 97: 361-368. (Pubitemid 40515752)
-
(2005)
Journal of Pharmacological Sciences
, vol.97
, Issue.3
, pp. 361-368
-
-
Kawai, H.1
Suzuki, T.2
Kobayashi, T.3
Sakurai, H.4
Ohata, H.5
Honda, K.6
Momose, K.7
Namekata, I.8
Tanaka, H.9
Shigenobu, K.10
Nakamura, R.11
Hayakawa, T.12
Kawanishi, T.13
-
17
-
-
38049119903
-
Overlapping cleavage motif selectivity of caspases: Implications for analysis of apoptotic pathways
-
McStay GP, Salvesen GS, Green DR. Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways. Cell Death Differ 2008; 15: 322-331.
-
(2008)
Cell Death Differ
, vol.15
, pp. 322-331
-
-
McStay, G.P.1
Salvesen, G.S.2
Green, D.R.3
-
18
-
-
77956095537
-
Mitochondria and cell death: Outer membrane permeabilization and beyond
-
Tait SW, Green DR. Mitochondria and cell death: outer membrane permeabilization and beyond. Nat Rev Mol Cell Biol 2010; 11: 621-632.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 621-632
-
-
Tait, S.W.1
Green, D.R.2
-
19
-
-
33746298246
-
Mechanisms of cytochrome c release from mitochondria
-
DOI 10.1038/sj.cdd.4401950, PII 4401950
-
Garrido C, Galluzzi L, Brunet M, Puig PE, Didelot C, Kroemer G. Mechanisms of cytochrome c release from mitochondria. Cell Death Differ 2006; 13: 1423-1433. (Pubitemid 44210346)
-
(2006)
Cell Death and Differentiation
, vol.13
, Issue.9
, pp. 1423-1433
-
-
Garrido, C.1
Galluzzi, L.2
Brunet, M.3
Puig, P.E.4
Didelot, C.5
Kroemer, G.6
-
22
-
-
0042009909
-
Impact of proapoptotic proteins Bax and Bak in tumor progression and response to treatment
-
Cartron PF, Juin P, Oliver L, Meflah K, Vallette FM. Impact of proapoptotic proteins Bax and Bak in tumor progression and response to treatment. Expert Rev Anticancer Ther 2003; 3: 563-570. (Pubitemid 37009854)
-
(2003)
Expert Review of Anticancer Therapy
, vol.3
, Issue.4
, pp. 563-570
-
-
Cartron, P.-F.1
Juin, P.2
Oliver, L.3
Meflah, K.4
Vallette, F.M.5
-
23
-
-
69449097373
-
BAX/BAK-independent mitoptosis during cell death induced by proteasome inhibition?
-
Lomonosova E, Ryerse J, Chinnadurai G. BAX/BAK-independent mitoptosis during cell death induced by proteasome inhibition? Mol Cancer Res 2009; 7: 1268-1284.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1268-1284
-
-
Lomonosova, E.1
Ryerse, J.2
Chinnadurai, G.3
-
24
-
-
33845603436
-
Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2
-
Lei X, Chen Y, Du G, Yu W, Wang X, Qu H et al. Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2. FASEB J 2006; 20: 2147-2149.
-
(2006)
FASEB J
, vol.20
, pp. 2147-2149
-
-
Lei, X.1
Chen, Y.2
Du, G.3
Yu, W.4
Wang, X.5
Qu, H.6
-
25
-
-
0034284637
-
Mitochondria as the central control point of apoptosis
-
DOI 10.1016/S0962-8924(00)01803-1, PII S0962892400018031
-
Desagher S, Martinou JC. Mitochondria as the central control point of apoptosis. Trends Cell Biol 2000; 10: 369-377. (Pubitemid 30612469)
-
(2000)
Trends in Cell Biology
, vol.10
, Issue.9
, pp. 369-377
-
-
Desagher, S.1
Martinou, J.-C.2
-
28
-
-
34548070795
-
Small molecules not direct activators of caspases [1]
-
DOI 10.1038/nchembio0907-519, PII NCHEMBIO0907519
-
Denault JB, Drag M, Salvesen GS, Alves J, Heidt AB, Deveraux Q et al. Small molecules not direct activators of caspases. Nat Chem Biol 2007; 3: 519; author reply 520. (Pubitemid 47294403)
-
(2007)
Nature Chemical Biology
, vol.3
, Issue.9
, pp. 519
-
-
Denault, J.-B.1
Drag, M.2
Salvesen, G.S.3
Alves, J.4
Heidt, A.B.5
Deveraux, Q.6
Harris, J.L.7
-
29
-
-
22344454056
-
Reconstitution of caspase-3 sensitizes MCF-7 breast cancer cells to radiation therapy
-
Yang XH, Edgerton S, Thor AD. Reconstitution of caspase-3 sensitizes MCF-7 breast cancer cells to radiation therapy. Int J Oncol 2005; 26: 1675-1680.
-
(2005)
Int J Oncol
, vol.26
, pp. 1675-1680
-
-
Yang, X.H.1
Edgerton, S.2
Thor, A.D.3
|