Prediction of human absorption of a trioxane antimalarial drug (CDRI 99/411) using an in-house validated in situ single-pass intestinal perfusion model

Arzneimittel-Forschung/Drug Research

Volumn 61, Issue 9, 2011, Pages 532-537

  Wahajuddin, ^a   Singh, Sheelendra Pratap ^a   Patel, Kushalkumar ^b   Pradhan, Tejaswini ^a   Siddiqui, Hefazat Hussain ^c   Singh, Shio Kumar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b National Institute of Pharmaceutical Education and Research (NIPER)   (India)

^c INTEGRAL UNIVERSITY   (India)

Author keywords

Antimalarial drug; CDRI 99 411; Human absorption; In situ permeability; Trioxane

Indexed keywords

99 411; ANTIMALARIAL AGENT; UNCLASSIFIED DRUG;

ARTICLE; DRUG ABSORPTION; DRUG BINDING; DRUG SOLUTION; DRUG STABILITY; DRUG STRUCTURE; FLOW RATE; FRACTIONATION; HUMAN; INTESTINE MUCOSA PERMEABILITY; INTESTINE PERFUSION; MALE; NONHUMAN; PHYSICAL CHEMISTRY; PREDICTION; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SINGLE PASS INTESTINAL PERFUSION;

EID: 80053394654     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296240     Document Type: Article

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