High-perfomance liqiud chromatography method development and validation for simultaneous determination of five model compounds, antipyrine metoprolol, ketoprofen, furosemide and phenol red, as a tool for standardization of rat in situ intestinal permeability studies using timed wavelength detection

Biomedical Chromatography

Volumn 20, Issue 4, 2006, Pages 349-357

  Chawla, Sonia ^a   Ghosh, Soma ^a   Sihorkar, Vaibhav ^a   Nellore, Ranjani ^a   Kumar, T R Shantha ^b   Srinivas, Nuggehally R ^a  

^a DR REDDY'S LABORATORIES LTD   (India)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

Antipyrine; Furosemide; Intestinal permeability; Ketoprofen; Metoprolol; Phenol red

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; DATA ACQUISITION; DIGITAL STORAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHENOLS; POTASSIUM COMPOUNDS;

ANTIPYRINE; FUROSEMIDES; INTESTINAL PERMEABILITIES; KETOPROFEN; METHOD DEVELOPMENT; METOPROLOL; MODEL COMPOUND; PERFOMANCE; PHENOL RED; SIMULTANEOUS DETERMINATIONS;

RATS;

FUROSEMIDE; KETOPROFEN; METHANOL; METOPROLOL; PHENAZONE; PHENOLSULFONPHTHALEIN; POTASSIUM DIHYDROGEN PHOSPHATE;

ACCURACY; ANALYTIC METHOD; ARTICLE; CHROMATOGRAPHY; COLD; CONTROLLED STUDY; DRUG PENETRATION; DRUG STRUCTURE; ELUTION; FLOW RATE; HIGH TEMPERATURE; INTESTINE MUCOSA PERMEABILITY; INTESTINE PERFUSION; NONHUMAN; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STANDARDIZATION; THAWING; TIME; VALIDATION PROCESS; ANIMAL; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSTRUMENTATION; INTESTINE ABSORPTION; METHODOLOGY; PERMEABILITY; PHYSIOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; VALIDATION STUDY;

ANIMALS; ANTIPYRINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FUROSEMIDE; INTESTINAL ABSORPTION; KETOPROFEN; METOPROLOL; PERMEABILITY; PHENOLSULFONPHTHALEIN; RATS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 33646066277     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.570     Document Type: Article

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