Framingham Heart Study genome-wide association: Results for pulmonary function measures

BMC Medical Genetics

Volumn 8, Issue SUPPL. 1, 2007, Pages

  Wilk, Jemma B ^a   Walter, Robert E ^a,b   Laramie, Jason M ^a,c   Gottlieb, Daniel J ^a,b,d   O'Connor, George T ^a,b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FRAMINGHAM HEART STUDY   (United States)

^c BOSTON UNIVERSITY   (United States)

^d VA BOSTON HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE O2; INTERLEUKIN 6 RECEPTOR; SUPEROXIDE DISMUTASE; VITAMIN D BINDING PROTEIN;

AGE; ARTICLE; AUTOSOME; BODY HEIGHT; BODY MASS; CHROMOSOME 1; CHROMOSOME 10; CHRONIC OBSTRUCTIVE LUNG DISEASE; COHORT ANALYSIS; CONTROLLED STUDY; FORCED EXPIRATORY FLOW; FORCED EXPIRATORY VOLUME; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC CODE; GENOTYPE; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PHENOTYPE; PREDICTION; SEX; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SPIROMETRY; STATISTICAL SIGNIFICANCE; UNINDEXED SEQUENCE; ADULT; CARDIOVASCULAR DISEASE; DISEASE PREDISPOSITION; FEMALE; GENETIC MARKER; GENETICS; GENOME; LUNG FUNCTION TEST; MALE; MIDDLE AGED; PATHOPHYSIOLOGY;

ADULT; CARDIOVASCULAR DISEASES; COHORT STUDIES; DISEASE SUSCEPTIBILITY; FEMALE; GENETIC MARKERS; GENOME, HUMAN; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY FUNCTION TESTS;

EID: 35748983541     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-8-S1-S8     Document Type: Article

References (28)

1. Mannino DM Homa DM Akinbami LJ Ford ES Redd SC Chronic obstructive pulmonary disease surveillance - United States, 1971-2000 Respiratory care 2002 47 10 1184-1199 12354338
2. Hoyert DL Heron MP Murphy SL Kung HC Deaths: Final data for 2003 Natl Vital Stat Rep 2006 54 13 1-120 16689256
3. Fabbri L Pauwels RA Hurd SS Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease: GOLD Executive Summary updated 2003 Copd 2004 1 1 105-141 discussion 103-104. 16997745
4. Silverman EK Chapman HA Drazen JM Weiss ST Rosner B Campbell EJ O'Donnell WJ Reilly JJ Ginns L Mentzer S Wain J Speizer FE Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis American journal of respiratory and critical care medicine 1998 157 6 Pt 1 1770-1778
5. Wilk JB Djousse L Arnett DK Rich SS Province MA Hunt SC Crapo RO Higgins M Myers RH Evidence for major genes influencing pulmonary function in the NHLBI family heart study Genet Epidemiol 2000 19 1 81-94 10.1002/ 1098-2272(200007)19:1<81::AID-GEPI6>3.0.CO;2-8 10861898
6. Demeo DL Mariani TJ Lange C Srisuma S Litonjua AA Celedon JC Lake SL Reilly JJ Chapman HA Mecham BH Haley KJ Sylvia JS Sparrow D Spira AE Beane J Pinto-Plata V Speizer FE Shapiro SD Weiss ST Silverman EK The SERPINE2 Gene Is Associated with Chronic Obstructive Pulmonary Disease American journal of human genetics 2006 78 2 253-264 1380249 16358219 10.1086/499828
7. Joost O Wilk JB Cupples LA Harmon M Shearman AM Baldwin CT O'Connor GT Myers RH Gottlieb DJ Genetic loci influencing lung function: A genome-wide scan in the Framingham Study American journal of respiratory and critical care medicine 2002 165 6 795-799
8. Wilk JB DeStefano AL Joost O Myers RH Cupples LA Slater K Atwood LD Heard-Costa NL Herbert A O'Connor GT Gottlieb DJ Linkage and association with pulmonary function measures on chromosome 6q27 in the Framingham Heart Study Human molecular genetics 2003 12 21 2745-2751 10.1093/hmg/ ddg311 12966033
9. Wilk JB Herbert A Shoemaker CM Gottlieb DJ Karamohamed S Secreted modular calcium-binding protein 2 haplotypes are associated with pulmonary function American journal of respiratory and critical care medicine 2007 175 6 554-560 10.1164/rccm.200601-110OC
10. ATS Standardization of Spirometry, 1994 Update. American Thoracic Society American journal of respiratory and critical care medicine 1995 152 3 1107-1136
11. Hankinson JL Odencrantz JR Fedan KB Spirometric reference values from a sample of the general U.S. population American journal of respiratory and critical care medicine 1999 159 1 179-187
12. Cupples LA Arruda HT Benjamin EJ D'Agostino RB Sr Demissie S DeStefano AL Dupuis J Falls K Fox CS Gottlieb DJ Govindaraju DR Guo CY Heard-Costa NL Hwang SJ Kathiresan S Kiel DP Laramie JM Larson MG Levy D Liu CY Lunetta KL Mailman MD Manning AK Meigs JB Murabito JM Newton-Cheh C O'Connor GT O'Donnell CJ Pandey MA Seshadri S Vasan RS Wang ZY Wilk JB Wolf PA Yang Q Atwood LD The Framingham Heart Study 100K SNP genome-wide association study resource: Overview of 17 phenotype working group reports BMC Med Genet 2007 8 Suppl 1 S1
13. Abecasis GR Cherny SS Cookson WO Cardon LR Merlin - rapid analysis of dense genetic maps using sparse gene flow trees Nature genetics 2002 30 1 97-101 10.1038/ng786 11731797
14. Almasy L Blangero J Multipoint quantitative-trait linkage analysis in general pedigrees American journal of human genetics 1998 62 5 1198-1211 1377101 9545414 10.1086/301844
15. Karolchik D Baertsch R Diekhans M Furey TS Hinrichs A Lu YT Roskin KM Schwartz M Sugnet CW Thomas DJ Weber RJ Haussler D Kent WJ The UCSC Genome Browser Database Nucleic acids research 2003 31 1 51-54 165576 12519945 10.1093/nar/gkg129
16. Kent WJ Sugnet CW Furey TS Roskin KM Pringle TH Zahler AM Haussler D The human genome browser at UCSC Genome research 2002 12 6 996-1006 186604 12045153 10.1101/gr.229102. Article published online before print in May 2002
17. Hersh CP Demeo DL Lange C Litonjua AA Reilly JJ Kwiatkowski D Laird N Sylvia JS Sparrow D Speizer FE Weiss ST Silverman EK Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations American journal of respiratory cell and molecular biology 2005 33 1 71-78 10.1165/rcmb.2005-0073OC
18. Young RP Hopkins R Black PN Eddy C Wu L Gamble GD Mills GD Garrett JE Eaton TE Rees MI Functional variants of antioxidant genes in smokers with COPD and in those with normal lung function Thorax 2006 61 5 394-399 10.1136/thx.2005.048512 16467073
19. Juul K Tybjaerg-Hansen A Marklund S Lange P Nordestgaard BG Genetically increased antioxidative protection and decreased chronic obstructive pulmonary disease American journal of respiratory and critical care medicine 2006 173 8 858-864 10.1164/rccm.200509-1387OC
20. Stemmler S Arinir U Klein W Rohde G Hoffjan S Wirkus N Reinitz-Rademacher K Bufe A Schultze-Werninghaus G Epplen JT Association of interleukin-8 receptor alpha polymorphisms with chronic obstructive pulmonary disease and asthma Genes and immunity 2005 6 3 225-230 10.1038/ sj.gene.6364181
21. Burgess JL Fierro MA Lantz RC Hysong TA Fleming JE Gerkin R Hnizdo E Conley SM Klimecki W Longitudinal decline in lung function: Evaluation of interleukin-10 genetic polymorphisms in firefighters Journal of occupational and environmental medicine/American College of Occupational and Environmental Medicine 2004 46 10 1013-1022 15602175
22. Hegab AE Sakamoto T Saitoh W Massoud HH Massoud HM Hassanein KM Sekizawa K Polymorphisms of IL4, IL13, and ADRB2 genes in COPD Chest 2004 126 6 1832-1839 10.1378/chest.126.6.1832 15596681
23. Celedon JC Lange C Raby BA Litonjua AA Palmer LJ DeMeo DL Reilly JJ Kwiatkowski DJ Chapman HA Laird N Sylvia JS Hernandez M Speizer FE Weiss ST Silverman EK The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD) Human molecular genetics 2004 13 15 1649-1656 10.1093/hmg/ddh171 15175276
24. Imboden M Downs SH Senn O Matyas G Brandli O Russi EW Schindler C Ackermann-Liebrich U Berger W Probst-Hensch NM Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study Respiratory research 2007 8 2 1781067 17217536 10.1186/1465-9921-8-2
25. Mukherjee B Salavaggione OE Pelleymounter LL Moon I Eckloff BW Schaid DJ Wieben ED Weinshilboum RM Glutathione S-transferase omega 1 and omega 2 pharmacogenomics Drug metabolism and disposition: The biological fate of chemicals 2006 34 7 1237-1246 10.1124/dmd.106.009613 16638819
26. Walter RE Wilk JB Larson MG Vasan RS Keaney JF Lipinska I O'Connor GT Benjamin EJ Systemic inflammation and COPD: The Framingham Heart Study Chest
27. Silverman EK Palmer LJ Mosley JD Barth M Senter JM Brown A Drazen JM Kwiatkowski DJ Chapman HA Campbell EJ Province MA Rao DC Reilly JJ Ginns LC Speizer FE Weiss ST Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease American journal of human genetics 2002 70 5 1229-1239 447597 11914989 10.1086/340316
28. Hudson BG Tryggvason K Sundaramoorthy M Neilson EG Alport's syndrome, Goodpasture's syndrome, and type IV collagen The New England journal of medicine 2003 348 25 2543-2556 10.1056/NEJMra022296 12815141