-
1
-
-
69249133245
-
Deciphering the impact of common genetic variation on lung cancer risk: A genome-wide association study
-
Broderick P, Wang Y, Vijayakarishnan J, Matakidou A, Spitz MR, et al. (2009) Deciphering the impact of common genetic variation on lung cancer risk: A genome-wide association study. Cancer Res; 69: 6633-6641.
-
(2009)
Cancer Res
, vol.69
, pp. 6633-6641
-
-
Broderick, P.1
Wang, Y.2
Vijayakarishnan, J.3
Matakidou, A.4
Spitz, M.R.5
-
2
-
-
2442628171
-
Genetics of COPD
-
Molfino NA (2004) Genetics of COPD. Chest; 125: 1929-1940.
-
(2004)
Chest
, vol.125
, pp. 1929-1940
-
-
Molfino, N.A.1
-
4
-
-
67649777117
-
The natural history of chronic airflow obstruction revisited: An analysis of the Framingham Offspring Cohort
-
Kohansal R, Martinez-Camblor P, Agusti A, Buist AS, Mannino DM, et al. (2009) The natural history of chronic airflow obstruction revisited: An analysis of the Framingham Offspring Cohort. Am J Respir Crit Care Med 180: 3-10.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 3-10
-
-
Kohansal, R.1
Martinez-Camblor, P.2
Agusti, A.3
Buist, A.S.4
Mannino, D.M.5
-
5
-
-
33751236493
-
Developing COPD: A 25 year follow up study of the general population
-
Løkke A, Lange P, Scharling H, Fabricius P, Vestbo J (2006) Developing COPD: A 25 year follow up study of the general population. Thorax 61: 935-939.
-
(2006)
Thorax
, vol.61
, pp. 935-939
-
-
Løkke, A.1
Lange, P.2
Scharling, H.3
Fabricius, P.4
Vestbo, J.5
-
6
-
-
0034644185
-
Environmental and heritable factors in the causation of cancer: Analyses of cohorts of twins from Sweden, Denmark and Finland
-
Lichtenstein P, Holm NV, Verkasalo PK, Iliadou A, Kaprio J (2000) Environmental and heritable factors in the causation of cancer: Analyses of cohorts of twins from Sweden, Denmark and Finland. N Eng J Med 343: 78-85.
-
(2000)
N Eng J Med
, vol.343
, pp. 78-85
-
-
Lichtenstein, P.1
Holm, N.V.2
Verkasalo, P.K.3
Iliadou, A.4
Kaprio, J.5
-
7
-
-
0024524884
-
Genotypic and phenotypic similarities in pulmonary function among family members of adult monozygotic and dizygotic twins
-
Redline S, Tishler PV, Rosner B, Lewitter FI, Vandenburgh M, et al. (1989) Genotypic and phenotypic similarities in pulmonary function among family members of adult monozygotic and dizygotic twins. Am J Epidemiol 129: 827-836.
-
(1989)
Am J Epidemiol
, vol.129
, pp. 827-836
-
-
Redline, S.1
Tishler, P.V.2
Rosner, B.3
Lewitter, F.I.4
Vandenburgh, M.5
-
8
-
-
69249086981
-
COPD prevalence is increased in lung cancer independence of age, gender and smoking history
-
Young RP, Hopkins RJ, Christmas T, Black PN, Metcalf P, et al. (2009) COPD prevalence is increased in lung cancer independence of age, gender and smoking history. Euro Respir J 34: 380-386.
-
(2009)
Euro Respir J
, vol.34
, pp. 380-386
-
-
Young, R.P.1
Hopkins, R.J.2
Christmas, T.3
Black, P.N.4
Metcalf, P.5
-
9
-
-
0038677958
-
Low lung function and incident lung cancer in the United States: Data from the first NHANES followup
-
Mannino DM, Aguayo SM, Petty TL, Redd SC (2003) Low lung function and incident lung cancer in the United States: Data from the first NHANES followup. Arch Int Med 163: 1475-1480.
-
(2003)
Arch Int Med
, vol.163
, pp. 1475-1480
-
-
Mannino, D.M.1
Aguayo, S.M.2
Petty, T.L.3
Redd, S.C.4
-
10
-
-
0017362875
-
Qualitative relationships between cigarette smoking and ventilatory function
-
Burrows B, Knudson RJ, Cline MG, Lebowitz MD (1977) Qualitative relationships between cigarette smoking and ventilatory function. Am Rev Respir Dis 115: 195-205.
-
(1977)
Am Rev Respir Dis
, vol.115
, pp. 195-205
-
-
Burrows, B.1
Knudson, R.J.2
Cline, M.G.3
Lebowitz, M.D.4
-
11
-
-
0023871240
-
Cumulative and reversible effects of lifetime smoking on simple tests of lung function in adults
-
Dockery DW, Speizer FE, Ferris BG, Jr., Ware JH, Louis TA, et al. (1988) Cumulative and reversible effects of lifetime smoking on simple tests of lung function in adults. Am Rev Respir Dis 137: 286-292.
-
(1988)
Am Rev Respir Dis
, vol.137
, pp. 286-292
-
-
Dockery, D.W.1
Speizer, F.E.2
Ferris Jr., B.G.3
Ware, J.H.4
Louis, T.A.5
-
12
-
-
37449001170
-
Forced expiratory volume in one second: Not just a lung function test but a marker of premature death from all causes
-
Young RP, Hopkins RJ, Eaton TE (2007) Forced expiratory volume in one second: Not just a lung function test but a marker of premature death from all causes. Eur Respir J 30(4): 616-622.
-
(2007)
Eur Respir J
, vol.30
, Issue.4
, pp. 616-622
-
-
Young, R.P.1
Hopkins, R.J.2
Eaton, T.E.3
-
13
-
-
52749088978
-
Association of radiographic emphysema and airflow obstruction with lung cancer
-
Wilson DO, Weissfeld JL, Balkan A, Schragin JG, Fuhrman CR, et al. (2008) Association of radiographic emphysema and airflow obstruction with lung cancer. Am J Respir Crit Care Med 178: 738-744.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 738-744
-
-
Wilson, D.O.1
Weissfeld, J.L.2
Balkan, A.3
Schragin, J.G.4
Fuhrman, C.R.5
-
14
-
-
37549021114
-
Assessing the relationship between lung cancer risk and emphysema detected on low dose CT of the chest
-
de Torres J, Bastarrika G, Wisnivesky JP, Alcaide AB, Campo A, et al. (2007) Assessing the relationship between lung cancer risk and emphysema detected on low dose CT of the chest. Chest 132: 1932-1938.
-
(2007)
Chest
, vol.132
, pp. 1932-1938
-
-
de Torres, J.1
Bastarrika, G.2
Wisnivesky, J.P.3
Alcaide, A.B.4
Campo, A.5
-
15
-
-
72649103693
-
Diagnosis of pulmonary malignancy after hospitalisation for pneumonia
-
Mortensen EM, Copeland LA, Pugh MJ, Fine MJ, Nakashima B, et al. (2010) Diagnosis of pulmonary malignancy after hospitalisation for pneumonia. Am J Med 123: 66-71.
-
(2010)
Am J Med
, vol.123
, pp. 66-71
-
-
Mortensen, E.M.1
Copeland, L.A.2
Pugh, M.J.3
Fine, M.J.4
Nakashima, B.5
-
16
-
-
35748983541
-
Framingham heart study genome-wide association: Results for pulmonary function measures
-
Wilk JB, Walter RE, Laramie JM, Gottlieb DJ, O'Connor GT (2007) Framingham heart study genome-wide association: Results for pulmonary function measures. BMC Med Genet 8(S1): S8.
-
(2007)
BMC Med Genet
, vol.8
, Issue.S1
-
-
Wilk, J.B.1
Walter, R.E.2
Laramie, J.M.3
Gottlieb, D.J.4
O'Connor, G.T.5
-
17
-
-
42649091460
-
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
-
Amos CI, Wu X, Broderick P, Gorlov IP, Gu J, et al. (2008) Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nature Genetics 40: 616-622.
-
(2008)
Nature Genetics
, vol.40
, pp. 616-622
-
-
Amos, C.I.1
Wu, X.2
Broderick, P.3
Gorlov, I.P.4
Gu, J.5
-
18
-
-
41649103682
-
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
-
Hung RJ, McKay JD, Gaborieau V, Boffetta P, Hashibe M, et al. (2008) A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 452: 633-637.
-
(2008)
Nature
, vol.452
, pp. 633-637
-
-
Hung, R.J.1
McKay, J.D.2
Gaborieau, V.3
Boffetta, P.4
Hashibe, M.5
-
19
-
-
41649103052
-
A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
-
Thorgeirsson TE, Geller F, Sulem P, Rafnar T, Wiste A, et al. (2008) A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 452: 638-642.
-
(2008)
Nature
, vol.452
, pp. 638-642
-
-
Thorgeirsson, T.E.1
Geller, F.2
Sulem, P.3
Rafnar, T.4
Wiste, A.5
-
20
-
-
63449101907
-
A genome-wide association study in chronic obstructive pulmonary disease (COPD): Identification of two major susceptibility loci
-
Pillai SG, Ge D, Zhu G, Kong X, Shianna KV, et al. (2009) A genome-wide association study in chronic obstructive pulmonary disease (COPD): Identification of two major susceptibility loci. PLoS Genetics 5: 1-8.
-
(2009)
PLoS Genetics
, vol.5
, pp. 1-8
-
-
Pillai, S.G.1
Ge, D.2
Zhu, G.3
Kong, X.4
Shianna, K.V.5
-
21
-
-
63449099623
-
A genomewide association study of pulmonary function measures in the Framingham Heart Study
-
Wilk JB, Chen T, Gottlieb DJ, Walter RE, Nagle MW, et al. (2009) A genomewide association study of pulmonary function measures in the Framingham Heart Study. PLoS Genetics 5(3): e1000429.
-
(2009)
PLoS Genetics
, vol.5
, Issue.3
-
-
Wilk, J.B.1
Chen, T.2
Gottlieb, D.J.3
Walter, R.E.4
Nagle, M.W.5
-
22
-
-
73349143302
-
Genome-wide association study identifies five loci associated with lung function
-
Repapi E, Sayers I, Wain LV, Burton PR, Johnson T, et al. (2009) Genome-wide association study identifies five loci associated with lung function. Nature Genetics 42: 36-44.
-
(2009)
Nature Genetics
, vol.42
, pp. 36-44
-
-
Repapi, E.1
Sayers, I.2
Wain, L.V.3
Burton, P.R.4
Johnson, T.5
-
23
-
-
73349111257
-
Metaanalyses of genome-wide association studies identify multiple loci associated with pulmonary function
-
Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, et al. (2009) Metaanalyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nature Genetics 42: 45-52.
-
(2009)
Nature Genetics
, vol.42
, pp. 45-52
-
-
Hancock, D.B.1
Eijgelsheim, M.2
Wilk, J.B.3
Gharib, S.A.4
Loehr, L.R.5
-
24
-
-
27144456779
-
Are COPD and lung cancer two manifestations of the same disease?
-
Petty TL (2005) Are COPD and lung cancer two manifestations of the same disease? Chest 128: 1895-1897.
-
(2005)
Chest
, vol.128
, pp. 1895-1897
-
-
Petty, T.L.1
-
25
-
-
30344458199
-
Familial lung cancer: Genetic susceptibility and relationship to chronic obstructive pulmonary disease
-
Schwartz AG, Ruckdeschel JC (2006) Familial lung cancer: Genetic susceptibility and relationship to chronic obstructive pulmonary disease. Am J Respir Crit Care Med 173: 16-22.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 16-22
-
-
Schwartz, A.G.1
Ruckdeschel, J.C.2
-
26
-
-
58849140039
-
Lung cancer gene associated with COPD: Triple whammy or possible confounding effect?
-
Young RP, Hopkins RJ, Hay BA, Epton MJ, Black PN, et al. (2008) Lung cancer gene associated with COPD: Triple whammy or possible confounding effect? Eur Respir J 32: 1-7.
-
(2008)
Eur Respir J
, vol.32
, pp. 1-7
-
-
Young, R.P.1
Hopkins, R.J.2
Hay, B.A.3
Epton, M.J.4
Black, P.N.5
-
27
-
-
65349122439
-
Lung cancer susceptibility model based on age, family history and genetic variants
-
Young RP, Hopkins RJ, Hay BA, Epton MJ, Mills GD, et al. (2009) Lung cancer susceptibility model based on age, family history and genetic variants. Plos One 4: e5302.
-
(2009)
Plos One
, vol.4
-
-
Young, R.P.1
Hopkins, R.J.2
Hay, B.A.3
Epton, M.J.4
Mills, G.D.5
-
28
-
-
78649740699
-
Chromosome 4q31 locus in COPD also associated with lung cancer
-
Young RP, Whittington CF, Hopkins RJ, Hay BA, Epton MJ, et al. (2010) Chromosome 4q31 locus in COPD also associated with lung cancer. Eur Respir J 36: 1375-1382.
-
(2010)
Eur Respir J
, vol.36
, pp. 1375-1382
-
-
Young, R.P.1
Whittington, C.F.2
Hopkins, R.J.3
Hay, B.A.4
Epton, M.J.5
-
29
-
-
64749083599
-
Lung cancer and chronic obstructive pulmonary disease: Needs and opportunities for integrated research
-
Punturieri A, Szabo E, Croxton TL, Shapiro SD, Dubinett SM (2009) Lung cancer and chronic obstructive pulmonary disease: Needs and opportunities for integrated research. JNCI 101: 554-559.
-
(2009)
JNCI
, vol.101
, pp. 554-559
-
-
Punturieri, A.1
Szabo, E.2
Croxton, T.L.3
Shapiro, S.D.4
Dubinett, S.M.5
-
30
-
-
34548032087
-
Genome-wide association studies provide new insights into type 2 diabetes aetiology
-
Frayling TM (2007) Genome-wide association studies provide new insights into type 2 diabetes aetiology. Nat Reviews Genet 8: 657-662.
-
(2007)
Nat Reviews Genet
, vol.8
, pp. 657-662
-
-
Frayling, T.M.1
-
31
-
-
68949191441
-
Genome-based prediction of common disease: Methodological considerations for future research
-
Janssens ACJW, van Duijn CM (2009) Genome-based prediction of common disease: methodological considerations for future research. Genome Med 1: 20.
-
(2009)
Genome Med
, vol.1
, pp. 20
-
-
Janssens, A.C.J.W.1
van Duijn, C.M.2
-
32
-
-
70349682910
-
A gene based risk score for lung cancer susceptibility in smokers and ex-smokers
-
Young RP, Hopkins RJ, Hay BA, Epton MJ, Mills GD, et al. (2009) A gene based risk score for lung cancer susceptibility in smokers and ex-smokers. Postgrad Med J 85: 515-524.
-
(2009)
Postgrad Med J
, vol.85
, pp. 515-524
-
-
Young, R.P.1
Hopkins, R.J.2
Hay, B.A.3
Epton, M.J.4
Mills, G.D.5
-
33
-
-
36749045699
-
Prevalence of chronic obstructive pulmonary disease among smokers aged 45 and up in Israel
-
Stav D, Raz M (2007) Prevalence of chronic obstructive pulmonary disease among smokers aged 45 and up in Israel. Isr Med Assoc J 9: 800-802.
-
(2007)
Isr Med Assoc J
, vol.9
, pp. 800-802
-
-
Stav, D.1
Raz, M.2
-
34
-
-
74549154414
-
A rigorous and comprehensive validation: Common genetic variations and lung cancer
-
Yang P, Yafei L, Jiang R, Cunningham JM, Zhang F, et al. (2010) A rigorous and comprehensive validation: Common genetic variations and lung cancer. Cancer Epidemiol Bio Prev 19: 240-244.
-
(2010)
Cancer Epidemiol Bio Prev
, vol.19
, pp. 240-244
-
-
Yang, P.1
Yafei, L.2
Jiang, R.3
Cunningham, J.M.4
Zhang, F.5
-
35
-
-
77649087948
-
The 15q24/25 susceptibility variant for lung cancer and COPD is associated with emphysema
-
Lambrechts D, Buysschaert I, Zanen P, Coolen J, Lays N, et al. (2010) The 15q24/25 susceptibility variant for lung cancer and COPD is associated with emphysema. Am J Resipr Crit Care Med 181: 486-493.
-
(2010)
Am J Resipr Crit Care Med
, vol.181
, pp. 486-493
-
-
Lambrechts, D.1
Buysschaert, I.2
Zanen, P.3
Coolen, J.4
Lays, N.5
-
37
-
-
40049098166
-
Cumulative association of five genetic variants with prostate cancer
-
Zheng SL, Sun J, Wiklund F, Smith S, Stattin P, et al. (2008) Cumulative association of five genetic variants with prostate cancer. NEJM 358: 910-919.
-
(2008)
NEJM
, vol.358
, pp. 910-919
-
-
Zheng, S.L.1
Sun, J.2
Wiklund, F.3
Smith, S.4
Stattin, P.5
-
38
-
-
0025893209
-
Floating absolute risk: An alternative to relative risk in survival and case-control analysis avoiding an arbitrary reference group
-
Easton DF, Peto J, Babiker AGAG (1991) Floating absolute risk: an alternative to relative risk in survival and case-control analysis avoiding an arbitrary reference group. Statistics in Medicine 10: 1025-1035.
-
(1991)
Statistics In Medicine
, vol.10
, pp. 1025-1035
-
-
Easton, D.F.1
Peto, J.2
Babiker, A.G.A.G.3
-
39
-
-
0346025731
-
Improved estimates of floating absolute risk
-
Plummer M (2004) Improved estimates of floating absolute risk. Statistics in Medicine 23: 93-104.
-
(2004)
Statistics In Medicine
, vol.23
, pp. 93-104
-
-
Plummer, M.1
-
40
-
-
0034118493
-
Inference of population structure from multilocus genotype data
-
Pritchard J, Stephens M, Donnelly P (2000) Inference of population structure from multilocus genotype data. Genetics 155: 945-959.
-
(2000)
Genetics
, vol.155
, pp. 945-959
-
-
Pritchard, J.1
Stephens, M.2
Donnelly, P.3
-
41
-
-
70449369066
-
Choosing between per-genotype, per-allele, and trend approaches for initial detection of genedisease association
-
Thankkinstian A, Thompson JR, Minelli C, Attia J (2009) Choosing between per-genotype, per-allele, and trend approaches for initial detection of genedisease association. J App Stat 36(6): 633-646.
-
(2009)
J App Stat
, vol.36
, Issue.6
, pp. 633-646
-
-
Thankkinstian, A.1
Thompson, J.R.2
Minelli, C.3
Attia, J.4
-
42
-
-
22244480031
-
Clinical Features of 5,628 Primary Lung Cancer Patients: Experience at Mayo Clinic from 1997 to 2003
-
Yang P, Allen MS, Aubry MC, Wampfler JA, Marks RS, et al. (2005) Clinical Features of 5,628 Primary Lung Cancer Patients: Experience at Mayo Clinic from 1997 to 2003. Chest 128: 452-462.
-
(2005)
Chest
, vol.128
, pp. 452-462
-
-
Yang, P.1
Allen, M.S.2
Aubry, M.C.3
Wampfler, J.A.4
Marks, R.S.5
-
43
-
-
66749114836
-
Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population
-
Jin G, Xu L, Shu Y, Tian T, Liang J, et al. (2009) Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population. Carcinogenesis 30: 987-990.
-
(2009)
Carcinogenesis
, vol.30
, pp. 987-990
-
-
Jin, G.1
Xu, L.2
Shu, Y.3
Tian, T.4
Liang, J.5
-
44
-
-
73449091199
-
Pharmacological actions of statins: Potential utility in COPD
-
Young RP, Hopkins R, Eaton TE (2009) Pharmacological actions of statins: potential utility in COPD. Eur Respir Rev 18: 222-232.
-
(2009)
Eur Respir Rev
, vol.18
, pp. 222-232
-
-
Young, R.P.1
Hopkins, R.2
Eaton, T.E.3
-
46
-
-
79751516594
-
Smoking has potential to initiate basement membrane disruption and epithelial mesenchymal transition in COPD
-
Sohal SS, Reid D, Soltani A, Ward C, Weston S, et al. (2009) Smoking has potential to initiate basement membrane disruption and epithelial mesenchymal transition in COPD. Abstract #1603 Vienna: European Respiratory Society Meeting.
-
(2009)
Abstract #1603 Vienna: European Respiratory Society Meeting
-
-
Sohal, S.S.1
Reid, D.2
Soltani, A.3
Ward, C.4
Weston, S.5
-
47
-
-
33745600428
-
Epithelialmesenchymal transition in lung cancer: Is tobacco the "smoking gun"?
-
Dasari V, Gallup M, Lemjabbar H, Maltseva I, McNamara N (2006) Epithelialmesenchymal transition in lung cancer: Is tobacco the "smoking gun"? Am J Respir Cell Mol Biol 35: 3-9.
-
(2006)
Am J Respir Cell Mol Biol
, vol.35
, pp. 3-9
-
-
Dasari, V.1
Gallup, M.2
Lemjabbar, H.3
Maltseva, I.4
McNamara, N.5
-
48
-
-
0043028316
-
Genetic susceptibility to lung cancer: The role of DNA damage and repair
-
Spitz MR, Wei Q, Dong Q, Amos CI, Wu X (2003) Genetic susceptibility to lung cancer: The role of DNA damage and repair. Cancer Epidemiol Biomarkers Prev 12: 689-697.
-
(2003)
Cancer Epidemiol Biomarkers Prev
, vol.12
, pp. 689-697
-
-
Spitz, M.R.1
Wei, Q.2
Dong, Q.3
Amos, C.I.4
Wu, X.5
-
49
-
-
37549053307
-
Collagen 1 promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-b signalling
-
Shintani Y, Maeda M, Chaika N, Johnson KR, Wheelock MJ (2008) Collagen 1 promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-b signalling. Am J Respir Cell Mol Biol 38: 95-104.
-
(2008)
Am J Respir Cell Mol Biol
, vol.38
, pp. 95-104
-
-
Shintani, Y.1
Maeda, M.2
Chaika, N.3
Johnson, K.R.4
Wheelock, M.J.5
-
50
-
-
0034658674
-
Oncogenic Ras downregulates rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition
-
Zondag GCM, Evers EE, ten Klooster JP, Janssen L, van der Kammen RA, et al. (2000) Oncogenic Ras downregulates rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition. J Cell Biol 149: 775-782.
-
(2000)
J Cell Biol
, vol.149
, pp. 775-782
-
-
Zondag, G.C.M.1
Evers, E.E.2
ten Klooster, J.P.3
Janssen, L.4
van der Kammen, R.A.5
-
51
-
-
67449098637
-
Chronic inflammation, chronic obstructive pulmonary disease and lung cancer
-
Lee G, Walser TC, Dubinett SM (2009) Chronic inflammation, chronic obstructive pulmonary disease and lung cancer. Curr Opin Pulm Med 15: 303-307.
-
(2009)
Curr Opin Pulm Med
, vol.15
, pp. 303-307
-
-
Lee, G.1
Walser, T.C.2
Dubinett, S.M.3
-
52
-
-
0036137130
-
Linkage disequilibrium and the mapping of complex human traits
-
Weiss KM, Clark AG (2002) Linkage disequilibrium and the mapping of complex human traits. Trends Genet 18: 19-24.
-
(2002)
Trends Genet
, vol.18
, pp. 19-24
-
-
Weiss, K.M.1
Clark, A.G.2
-
53
-
-
77249134594
-
Rare variants create synthetic genome-wide associations
-
Dickson SP, Wang K, Krantz I, Hakonarson H, Goldstein DB (2010) Rare variants create synthetic genome-wide associations. PLoS Biol 8: e1000294.
-
(2010)
PLoS Biol
, vol.8
-
-
Dickson, S.P.1
Wang, K.2
Krantz, I.3
Hakonarson, H.4
Goldstein, D.B.5
-
54
-
-
34447289205
-
The non-neuronal cholinergic system in the airways: An unappreciated regulatory role in pulmonary inflammation?
-
Gwilt CR, Donnelly LE, Rogers DF (2007) The non-neuronal cholinergic system in the airways: An unappreciated regulatory role in pulmonary inflammation? Pharmacol Therapeut 115: 208-222.
-
(2007)
Pharmacol Therapeut
, vol.115
, pp. 208-222
-
-
Gwilt, C.R.1
Donnelly, L.E.2
Rogers, D.F.3
-
55
-
-
34249284421
-
Nitrosamines as nicotinic receptor ligands
-
Schuller HM (2007) Nitrosamines as nicotinic receptor ligands. Life Sci 80: 2274-2280.
-
(2007)
Life Sci
, vol.80
, pp. 2274-2280
-
-
Schuller, H.M.1
-
56
-
-
51349156208
-
Variants in nicotinic receptors and risk for nicotine dependence
-
Bierut LJ, Stitzel JA, Wang JC, Hinrichs AL, Grucza RA, et al. (2008) Variants in nicotinic receptors and risk for nicotine dependence. Am J Psychiatry 165: 1163-1171.
-
(2008)
Am J Psychiatry
, vol.165
, pp. 1163-1171
-
-
Bierut, L.J.1
Stitzel, J.A.2
Wang, J.C.3
Hinrichs, A.L.4
Grucza, R.A.5
-
57
-
-
33744785962
-
Variants in the GH-IGF axis confer susceptibility to lung cancer
-
Rudd MF, Webb EL, Matakidou A, Sellick GS, Williams RD, et al. (2006) Variants in the GH-IGF axis confer susceptibility to lung cancer. Genome Res. 16: 693-701.
-
(2006)
Genome Res
, vol.16
, pp. 693-701
-
-
Rudd, M.F.1
Webb, E.L.2
Matakidou, A.3
Sellick, G.S.4
Williams, R.D.5
-
58
-
-
34147156192
-
HLA-Bassociated transcript 3 (BAT3)/Scythe is essential for p300-mediated acetylation of p53
-
Sasaki T, Gan EC, Wakeham A, Kornbluth S, Mak TW, et al. (2007) HLA-Bassociated transcript 3 (BAT3)/Scythe is essential for p300-mediated acetylation of p53. Genes and Development 21: 848-861.
-
(2007)
Genes and Development
, vol.21
, pp. 848-861
-
-
Sasaki, T.1
Gan, E.C.2
Wakeham, A.3
Kornbluth, S.4
Mak, T.W.5
-
59
-
-
73149099640
-
Mechanisms of lung development: Contribution to adult lung disease and relevance to chronic obstructive pulmonary disease
-
Shi W, Chen F, Cardoso WV (2009) Mechanisms of lung development: Contribution to adult lung disease and relevance to chronic obstructive pulmonary disease. Proc Am Thorac Soc 6: 558-563.
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 558-563
-
-
Shi, W.1
Chen, F.2
Cardoso, W.V.3
-
60
-
-
0242669237
-
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
-
Watkins DN, Berman DM, Burkholder SG, Wang B, Beachy PA, et al. (2003) Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature 422: 313-317.
-
(2003)
Nature
, vol.422
, pp. 313-317
-
-
Watkins, D.N.1
Berman, D.M.2
Burkholder, S.G.3
Wang, B.4
Beachy, P.A.5
-
61
-
-
37549053307
-
Collagen I promotes epithelial-to-Mesenchymal Transition in lung cancer cells via transforming growth factor- signalling
-
Shintani Y, Maeda M, Chaika N, Johnson KR, Wheelock MJ (2008) Collagen I promotes epithelial-to-Mesenchymal Transition in lung cancer cells via transforming growth factor- signalling. Am J Respir Cell Mol Biol 38: 95-104.
-
(2008)
Am J Respir Cell Mol Biol
, vol.38
, pp. 95-104
-
-
Shintani, Y.1
Maeda, M.2
Chaika, N.3
Johnson, K.R.4
Wheelock, M.J.5
-
62
-
-
38949161959
-
Radical generation and alterations of erythrocyte integrity as bio-indicators of diagnostic or prognostic value in COPD?
-
Minetti M, Leto TL, Malorni W (2008) Radical generation and alterations of erythrocyte integrity as bio-indicators of diagnostic or prognostic value in COPD? Antioxidants & Redox Signaling 10: 829-839.
-
(2008)
Antioxidants & Redox Signaling
, vol.10
, pp. 829-839
-
-
Minetti, M.1
Leto, T.L.2
Malorni, W.3
-
63
-
-
77649189442
-
Variants in FAM13A are associated with chronic obstructive pulmonary disease
-
Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, et al. (2010) Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nature Genetics 42: 200-202.
-
(2010)
Nature Genetics
, vol.42
, pp. 200-202
-
-
Cho, M.H.1
Boutaoui, N.2
Klanderman, B.J.3
Sylvia, J.S.4
Ziniti, J.P.5
-
64
-
-
79751516305
-
FAM13A locus in COPD independently associated with lung cancer - evidence of a molecular genetic link between COPD and lung cancer
-
Young RP, Hopkins RJ, Hay BA, Whittington CF, Epton MJ, et al. (2011) FAM13A locus in COPD independently associated with lung cancer - evidence of a molecular genetic link between COPD and lung cancer. App Clin Genet 4: 1-10.
-
(2011)
App Clin Genet
, vol.4
, pp. 1-10
-
-
Young, R.P.1
Hopkins, R.J.2
Hay, B.A.3
Whittington, C.F.4
Epton, M.J.5
-
66
-
-
63949084246
-
Expression of ADAMs ("a disintegrin and metalloprotease") in the human lung
-
Dijkstra A, Postma DS, Noordhoek JA, Ladewijk ME, Kauffman HF, et al. (2009) Expression of ADAMs ("a disintegrin and metalloprotease") in the human lung. Virchows Arch 454: 441-449.
-
(2009)
Virchows Arch
, vol.454
, pp. 441-449
-
-
Dijkstra, A.1
Postma, D.S.2
Noordhoek, J.A.3
Ladewijk, M.E.4
Kauffman, H.F.5
-
67
-
-
69249159918
-
ADAM19/adamalysin 19 structure, function, and role as a putative target in tumors and inflammatory diseases
-
Qi B, Newcomer RG, Sang QXA (2009) ADAM19/adamalysin 19 structure, function, and role as a putative target in tumors and inflammatory diseases. Current Pharmaceutical Design 15: 2336-2348.
-
(2009)
Current Pharmaceutical Design
, vol.15
, pp. 2336-2348
-
-
Qi, B.1
Newcomer, R.G.2
Sang, Q.X.A.3
-
68
-
-
59149091340
-
Sequence variants at the TERT-CLPTM1L locus associate with many cancer types
-
Rafnar T, Sulem P, Stacey SN, Geller F, Gudmundsson S, et al. (2009) Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. Nature Genetics 41: 221-227.
-
(2009)
Nature Genetics
, vol.41
, pp. 221-227
-
-
Rafnar, T.1
Sulem, P.2
Stacey, S.N.3
Geller, F.4
Gudmundsson, S.5
-
69
-
-
33845441144
-
Genetic variation is associated with C-reactive protein levels in the third national health and nutrition examination survey
-
Crawford DC, Sanders CL, Qin X, Smith JD, Shephard C, et al. (2006) Genetic variation is associated with C-reactive protein levels in the third national health and nutrition examination survey. Circulation 114: 2458-2465.
-
(2006)
Circulation
, vol.114
, pp. 2458-2465
-
-
Crawford, D.C.1
Sanders, C.L.2
Qin, X.3
Smith, J.D.4
Shephard, C.5
-
70
-
-
59649108881
-
High-sensitive C-reactive protein is associated with reduced lung function in young adults
-
Rasmussen F, Mikkelsen D, Hancox RJ, Lambrechtsen J, Nybo M, et al. (2009) High-sensitive C-reactive protein is associated with reduced lung function in young adults. Euro Respir J 33: 382-388.
-
(2009)
Euro Respir J
, vol.33
, pp. 382-388
-
-
Rasmussen, F.1
Mikkelsen, D.2
Hancox, R.J.3
Lambrechtsen, J.4
Nybo, M.5
-
71
-
-
65549122953
-
Baseline C-reactive protein is associated with incident cancer and survival in patients with cancer
-
Allin KH, Bojesen SE, Nordestgaard BG (2009) Baseline C-reactive protein is associated with incident cancer and survival in patients with cancer. J Clin Oncol 27: 2217-2224.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2217-2224
-
-
Allin, K.H.1
Bojesen, S.E.2
Nordestgaard, B.G.3
-
72
-
-
0036562502
-
RAGE and arthritis: The G82S polymorphism amplifies the inflammatory response
-
Hofmann MA, Dury S, Hudson BI, Gleason MR, Qu W, et al. (2002) RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response. Genes Immun 3: 123-135.
-
(2002)
Genes Immun
, vol.3
, pp. 123-135
-
-
Hofmann, M.A.1
Dury, S.2
Hudson, B.I.3
Gleason, M.R.4
Qu, W.5
-
73
-
-
77952307233
-
Expression of High-Mobility Group Box 1 and of Receptor for Advanced Glycation End products in Chronic Obstructive Pulmonary Disease
-
Ferhani N, Letuve S, Kozhich A, Thibaudeau D, Grandsaigne M, et al. (2010) Expression of High-Mobility Group Box 1 and of Receptor for Advanced Glycation End products in Chronic Obstructive Pulmonary Disease. Am J Resipr Crit Care Med 181: 917-927.
-
(2010)
Am J Resipr Crit Care Med
, vol.181
, pp. 917-927
-
-
Ferhani, N.1
Letuve, S.2
Kozhich, A.3
Thibaudeau, D.4
Grandsaigne, M.5
-
74
-
-
13844276534
-
Downregulation of the receptor for advanced glycation end-products (RAGE) supports non-small cell lung carcinoma
-
Bartling B, Hofmann HS, Weigle B, Silber R-E, Simm A (2005) Downregulation of the receptor for advanced glycation end-products (RAGE) supports non-small cell lung carcinoma. Carcinogenesis 26: 293-301.
-
(2005)
Carcinogenesis
, vol.26
, pp. 293-301
-
-
Bartling, B.1
Hofmann, H.S.2
Weigle, B.3
Silber, R.-E.4
Simm, A.5
-
75
-
-
0037421584
-
Inheritance and drug response
-
Weinshilboum R (2003) Inheritance and drug response. N Eng J Med 348: 529-537.
-
(2003)
N Eng J Med
, vol.348
, pp. 529-537
-
-
Weinshilboum, R.1
-
76
-
-
0023187149
-
Airways obstruction and the risk for lung cancer
-
Tockman MS, Anthonisen NR, Wright EC, Donithan MG, et al. (1987) Airways obstruction and the risk for lung cancer. Annal Int Med 106: 512-518.
-
(1987)
Annal Int Med
, vol.106
, pp. 512-518
-
-
Tockman, M.S.1
Anthonisen, N.R.2
Wright, E.C.3
Donithan, M.G.4
-
77
-
-
0036683267
-
Hospitalizations and mortality in the Lung Health Study
-
Anthonisen NR, Connett JE, Enright PL, Manfreda J, et al. (2002) Hospitalizations and mortality in the Lung Health Study. Am J Resipr Crit Care Med 166: 333-339.
-
(2002)
Am J Resipr Crit Care Med
, vol.166
, pp. 333-339
-
-
Anthonisen, N.R.1
Connett, J.E.2
Enright, P.L.3
Manfreda, J.4
-
78
-
-
69249098135
-
Distinct clinical phenotypes of airways disease defined by cluster analysis
-
Weatherall M, Travers J, Shirtcliffe PM, Marsh SE, Williams MV, et al. (2009) Distinct clinical phenotypes of airways disease defined by cluster analysis. Eur Respir J 34: 812-818.
-
(2009)
Eur Respir J
, vol.34
, pp. 812-818
-
-
Weatherall, M.1
Travers, J.2
Shirtcliffe, P.M.3
Marsh, S.E.4
Williams, M.V.5
-
79
-
-
0032586927
-
Decline in FEV1 related to smoking status in individuals with severe alpha1-antitrypsin deficiency (PiZZ)
-
Piitulainen E, Eriksson S (1999) Decline in FEV1 related to smoking status in individuals with severe alpha1-antitrypsin deficiency (PiZZ). Eur Respir J 13: 247-251.
-
(1999)
Eur Respir J
, vol.13
, pp. 247-251
-
-
Piitulainen, E.1
Eriksson, S.2
-
80
-
-
76249096292
-
Evaluation of genetic tests for susceptibility to complex diseases: Why, when and how?
-
Wright CF, Kroese M (2010) Evaluation of genetic tests for susceptibility to complex diseases: why, when and how? Hum Genet 127: 125-134.
-
(2010)
Hum Genet
, vol.127
, pp. 125-134
-
-
Wright, C.F.1
Kroese, M.2
-
81
-
-
65249131768
-
Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene
-
You M, Wang D, Liu P, Vikis H, James M, et al. (2009) Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. Clin Cancer Res 15: 2666-2674.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2666-2674
-
-
You, M.1
Wang, D.2
Liu, P.3
Vikis, H.4
James, M.5
-
82
-
-
0033547616
-
When can a risk factor be used as a worthwhile screening test?
-
Wald NJ, Hackshaw AK (1999) When can a risk factor be used as a worthwhile screening test? Brit Med J 319: 1562-1565.
-
(1999)
Brit Med J
, vol.319
, pp. 1562-1565
-
-
Wald, N.J.1
Hackshaw, A.K.2
-
83
-
-
11244337302
-
Complex segregation analysis reveals a multigene model for lung cancer
-
Xu H, Spitz MR, Amos CI, Shete S (2005) Complex segregation analysis reveals a multigene model for lung cancer. Hum Genet 116: 121-127.
-
(2005)
Hum Genet
, vol.116
, pp. 121-127
-
-
Xu, H.1
Spitz, M.R.2
Amos, C.I.3
Shete, S.4
-
84
-
-
0034089945
-
Cancer risk and low-penetrance susceptibility genes in gene-environment interactions
-
Shields P, Harris C (2000) Cancer risk and low-penetrance susceptibility genes in gene-environment interactions. J Clin Oncol 18: 2309-2315.
-
(2000)
J Clin Oncol
, vol.18
, pp. 2309-2315
-
-
Shields, P.1
Harris, C.2
-
85
-
-
40949127393
-
How to interpret a genome-wide association study
-
Pearson TA, Manolio TA (2008) How to interpret a genome-wide association study. JAMA 299: 1335-1344.
-
(2008)
JAMA
, vol.299
, pp. 1335-1344
-
-
Pearson, T.A.1
Manolio, T.A.2
|