Epac1-mediated, high glucose-induced renal proximal tubular cells hypertrophy via the Akt/p21 pathway

American Journal of Pathology

Volumn 179, Issue 4, 2011, Pages 1706-1718

  Sun, Lin ^a,b   Kondeti, Vinay K ^a   Xie, Ping ^a   Raparia, Kirtee ^a   Kanwar, Yashpal S ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTER; CYCLIC AMP; CYCLIC AMP 1; CYCLIC AMP DEPENDENT PROTEIN KINASE 1; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1B; DNA FRAGMENT; GLUCOSE; GUANINE NUCLEOTIDE BINDING PROTEIN; P21 ACTIVATED KINASE; PROTEIN KINASE B; PROTEIN P21; RAP PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL STRAIN COS7; CODON; DATA ANALYSIS; DNA ISOLATION; GENE MUTATION; GENETIC TRANSFECTION; HEART; HUMAN; HUMAN CELL; KIDNEY HYPERTROPHY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MEDICAL RECORD; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN SYNTHESIS;

ANIMALS; CELL CYCLE; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION PROFILING; GLUCOSE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; HYPERTROPHY; KIDNEY TUBULES, PROXIMAL; MICE; ORGAN SPECIFICITY; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STREPTOZOCIN;

EID: 80053254049     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.06.035     Document Type: Article

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