MafB interacts with Gcm2 and regulates parathyroid hormone expression and parathyroid development

Journal of Bone and Mineral Research

Volumn 26, Issue 10, 2011, Pages 2463-2472

  Kamitani Kawamoto, Akiyo ^a   Hamada, Michito ^b   Moriguchi, Takashi ^c   Miyai, Masashi ^a   Saji, Fumie ^d   Hatamura, Ikuji ^e   Nishikawa, Keizo ^f   Takayanagi, Hiroshi ^f,g   Hitoshi, Seiji ^h   Ikenaka, Kazuhiro ^h   Hosoya, Toshihiko ⁱ   Hotta, Yoshiki ^j   Takahashi, Satoru ^b   Kataoka, Kohsuke ^a  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^e KANSAI UNIVERSITY OF HEALTH SCIENCES   (Japan)

^f TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^g JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^h NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

ⁱ RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^j NATIONAL INSTITUTE OF GENETICS   (Japan)

more..

Author keywords

GCM2; MafB; parathyroid gland; parathyroid hormone; transcriptional regulation

Indexed keywords

PARATHYROID HORMONE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GCM2; TRANSCRIPTION FACTOR MAFB; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BONE MINERALIZATION; EMBRYO; GENE EXPRESSION REGULATION; HORMONE RELEASE; MOUSE; NONHUMAN; PARATHYROID GLAND; PROMOTER REGION; PROTEIN PROTEIN INTERACTION;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; IMMUNOHISTOCHEMISTRY; MAFB TRANSCRIPTION FACTOR; MICE; MICE, INBRED C57BL; NUCLEAR PROTEINS; PARATHYROID GLANDS; PARATHYROID HORMONE; REAL-TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS;

EID: 80053198680     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.458     Document Type: Article

References (44)

1. Kovacs CS, Chafe LL, Fudge NJ, Friel JK, Manley NR,. PTH regulates fetal blood calcium and skeletal mineralization independently of PTHrP. Endocrinology. 2001; 142 (11): 4983-93. (Pubitemid 33022375)
2. Simmonds CS, Karsenty G, Karaplis AC, Kovacs CS,. Parathyroid hormone regulates fetal-placental mineral homeostasis. J Bone Miner Res. 2010; 25 (3): 594-605.
3. Graham A, Smith A,. Patterning the pharyngeal arches. Bioessays. 2001; 23 (1): 54-61. (Pubitemid 32100501)
4. Kameda Y, Arai Y, Nishimaki T, Chisaka O,. The role of Hoxa3 gene in parathyroid gland organogenesis of the mouse. J Histochem Cytochem. 2004; 52 (5): 641-51. (Pubitemid 38658196)
5. Manley NR, Capecchi MR,. The role of Hoxa-3 in mouse thymus and thyroid development. Development. 1995; 121 (7): 1989-2003.
6. Manley NR, Capecchi MR,. Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands. Dev Biol. 1998; 195 (1): 1-15. (Pubitemid 28146373)
7. Wallin J, Eibel H, Neubuser A, Wilting J, Koseki H, Balling R,. Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation. Development. 1996; 122 (1): 23-30. (Pubitemid 26038415)
8. Su DM, Manley NR,. Hoxa3 and pax1 transcription factors regulate the ability of fetal thymic epithelial cells to promote thymocyte development. J Immunol. 2000; 164 (11): 5753-60. (Pubitemid 30389818)
9. Su D, Ellis S, Napier A, Lee K, Manley NR,. Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis. Dev Biol. 2001; 236 (2): 316-29. (Pubitemid 32756987)
10. Xu PX, Zheng W, Laclef C, Maire P, Maas RL, Peters H, Xu X,. Eya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroid. Development. 2002; 129 (13): 3033-44. (Pubitemid 34874279)
11. Zou D, Silvius D, Davenport J, Grifone R, Maire P, Xu PX,. Patterning of the third pharyngeal pouch into thymus/parathyroid by Six and Eya1. Dev Biol. 2006; 293 (2): 499-512.
12. Gordon J, Bennett AR, Blackburn CC, Manley NR,. Gcm2 and Foxn1 mark early parathyroid- and thymus-specific domains in the developing third pharyngeal pouch. Mech Dev. 2001; 103 (1-2): 141-3. (Pubitemid 32457917)
13. Moore-Scott BA, Manley NR,. Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs. Dev Biol. 2005; 278 (2): 323-35. (Pubitemid 40175032)
14. Patel SR, Gordon J, Mahbub F, Blackburn CC, Manley NR,. Bmp4 and Noggin expression during early thymus and parathyroid organogenesis. Gene Expr Patterns. 2006; 6 (8): 794-9. (Pubitemid 44334730)
15. Kim J, Jones BW, Zock C, Chen Z, Wang H, Goodman CS, Anderson DJ,. Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing. Proc Natl Acad Sci USA. 1998; 95 (21): 12364-9. (Pubitemid 28483771)
16. Gunther T, Chen ZF, Kim J, Priemel M, Rueger JM, Amling M, Moseley JM, Martin TJ, Anderson DJ, Karsenty G,. Genetic ablation of parathyroid glands reveals another source of parathyroid hormone. Nature. 2000; 406 (6792): 199-203. (Pubitemid 30469004)
17. Ding C, Buckingham B, Levine MA,. Familial isolated hypoparathyroidism caused by a mutation in the gene for the transcription factor GCMB. J Clin Invest. 2001; 108 (8): 1215-20. (Pubitemid 32995380)
18. Baumber L, Tufarelli C, Patel S, King P, Johnson CA, Maher ER, Trembath RC,. Identification of a novel mutation disrupting the DNA binding activity of GCM2 in autosomal recessive familial isolated hypoparathyroidism. J Med Genet. 2005; 42 (5): 443-8. (Pubitemid 40685688)
19. Thomee C, Schubert SW, Parma J, Le PQ, Hashemolhosseini S, Wegner M, Abramowicz MJ,. GCMB mutation in familial isolated hypoparathyroidism with residual secretion of parathyroid hormone. J Clin Endocrinol Metab. 2005; 90 (5): 2487-92. (Pubitemid 40686281)
20. Mannstadt M, Bertrand G, Muresan M, Weryha G, Leheup B, Pulusani SR, Grandchamp B, Juppner H, Silve C,. Dominant-negative GCMB mutations cause an autosomal dominant form of hypoparathyroidism. J Clin Endocrinol Metab. 2008; 93 (9): 3568-76.
21. Blanchi B, Kelly LM, Viemari JC, Lafon I, Burnet H, Bevengut M, Tillmanns S, Daniel L, Graf T, Hilaire G, Sieweke MH,. MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth. Nat Neurosci. 2003; 6 (10): 1091-100.
22. Moriguchi T, Hamada M, Morito N, Terunuma T, Hasegawa K, Zhang C, Yokomizo T, Esaki R, Kuroda E, Yoh K, Kudo T, Nagata M, Greaves DR, Engel JD, Yamamoto M, Takahashi S,. MafB is essential for renal development and F4/80 expression in macrophages. Mol Cell Biol. 2006; 26 (15): 5715-27. (Pubitemid 44134328)
23. Aziz A, Vanhille L, Mohideen P, Kelly LM, Otto C, Bakri Y, Mossadegh N, Sarrazin S, Sieweke MH,. Development of macrophages with altered actin organization in the absence of MafB. Mol Cell Biol. 2006; 26 (18): 6808-18. (Pubitemid 44387631)
24. Kim K, Kim JH, Lee J, Jin HM, Kook H, Kim KK, Lee SY, Kim N,. MafB negatively regulates RANKL-mediated osteoclast differentiation. Blood. 2007; 109 (8): 3253-9. (Pubitemid 46572510)
25. Nishikawa K, Nakashima T, Hayashi M, Fukunaga T, Kato S, Kodama T, Takahashi S, Calame K, Takayanagi H,. Blimp1-mediated repression of negative regulators is required for osteoclast differentiation. Proc Natl Acad Sci USA. 2010; 107 (7): 3117-22.
26. Sadl V, Jin F, Yu J, Cui S, Holmyard D, Quaggin S, Barsh G, Cordes S,. The mouse Kreisler (Krml1/MafB) segmentation gene is required for differentiation of glomerular visceral epithelial cells. Dev Biol. 2002; 249 (1): 16-29.
27. Artner I, Blanchi B, Raum JC, Guo M, Kaneko T, Cordes S, Sieweke M, Stein R,. MafB is required for islet beta cell maturation. Proc Natl Acad Sci USA. 2007; 104 (10): 3853-8. (Pubitemid 47181543)
28. Artner I, Le Lay J, Hang Y, Elghazi L, Schisler JC, Henderson E, Sosa-Pineda B, Stein R,. MafB: an activator of the glucagon gene expressed in developing islet α- and β-cells. Diabetes. 2006; 55 (2): 297-304. (Pubitemid 43343256)
29. Matsuoka TA, Zhao L, Artner I, Jarrett HW, Friedman D, Means A, Stein R,. Members of the large Maf transcription family regulate insulin gene transcription in islet β cells. Mol Cell Biol. 2003; 23 (17): 6049-62. (Pubitemid 37013085)
30. Aramata S, Han SI, Yasuda K, Kataoka K,. Synergistic activation of the insulin gene promoter by the beta-cell enriched transcription factors MafA, Beta2, and Pdx1. Biochim Biophys Acta. 2005; 1730 (1): 41-6. (Pubitemid 41008611)
31. Nishimura W, Kondo T, Salameh T, El Khattabi I, Dodge R, Bonner-Weir S, Sharma A,. A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev Biol. 2006; 293 (2): 526-39.
32. Nishimura W, Rowan S, Salameh T, Maas RL, Bonner-Weir S, Sell SM, Sharma A,. Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice. Dev Biol. 2008; 314 (2): 443-56.
33. Kim S, Koga T, Isobe M, Kern BE, Yokochi T, Chin YE, Karsenty G, Taniguchi T, Takayanagi H,. Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation. Genes Dev. 2003; 17 (16): 1979-91. (Pubitemid 36999325)
34. Yang X, Matsuda K, Bialek P, Jacquot S, Masuoka HC, Schinke T, Li L, Brancorsini S, Sassone-Corsi P, Townes TM, Hanauer A, Karsenty G,. ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell. 2004; 117 (3): 387-98. (Pubitemid 38534544)
35. Vasicek TJ, McDevitt BE, Freeman MW, Fennick BJ, Hendy GN, Potts JT Jr, Rich A, Kronenberg HM,. Nucleotide sequence of the human parathyroid hormone gene. Proc Natl Acad Sci USA. 1983; 80 (8): 2127-31. (Pubitemid 13097148)
36. Kanai K, Reza HM, Kamitani A, Hamazaki Y, Han SI, Yasuda K, Kataoka K,. SUMOylation negatively regulates transcriptional and oncogenic activities of MafA. Genes Cells. 2010; 15 (9): 971-82.
37. Kataoka K, Yoshitomo-Nakagawa K, Shioda S, Nishizawa M,. A set of Hox proteins interact with the Maf oncoprotein to inhibit its DNA binding, transactivation, and transforming activities. J Biol Chem. 2001; 276 (1): 819-26. (Pubitemid 32050383)
38. Kataoka K, Han SI, Shioda S, Hirai M, Nishizawa M, Handa H,. MafA is a glucose-regulated and pancreatic β-cell-specific transcriptional activator for the insulin gene. J Biol Chem. 2002; 277 (51): 49903-10. (Pubitemid 36014439)
39. Liu C, Saito F, Liu Z, Lei Y, Uehara S, Love P, Lipp M, Kondo S, Manley N, Takahama Y,. Coordination between CCR7- and CCR9-mediated chemokine signals in prevascular fetal thymus colonization. Blood. 2006; 108 (8): 2531-9.
40. Liu Z, Yu S, Manley NR,. Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia. Dev Biol. 2007; 305 (1): 333-46. (Pubitemid 46589422)
41. Thomas ML, Anast CS, Forte LR,. Regulation of calcium homeostasis in the fetal and neonatal rat. Am J Physiol. 1981; 240 (4): E367-72.
42. Hsu SC, Levine MA,. Perinatal calcium metabolism: physiology and pathophysiology. Semin Neonatol. 2004; 9 (1): 23-36. (Pubitemid 38112117)
43. Canaff L, Zhou X, Mosesova I, Cole DE, Hendy GN,. Glial cells missing-2 (GCM2) transactivates the calcium-sensing receptor gene: effect of a dominant-negative GCM2 mutant associated with autosomal dominant hypoparathyroidism. Hum Mutat. 2009; 30 (1): 85-92.
44. Correa P, Akerstrom G, Westin G,. Underexpression of Gcm2, a master regulatory gene of parathyroid gland development, in adenomas of primary hyperparathyroidism. Clin Endocrinol (Oxf). 2002; 57 (4): 501-5. (Pubitemid 35216301)