Detouring the undesired route of Helicobacter pylori-induced gastric carcinogenesis

Cancers

Volumn 3, Issue 3, 2011, Pages 3018-3028

  Kim, Eun Hee ^a   Hong, Kyung Sook ^a   Hong, Hua ^a   Hahm, Ki Baik ^a,b  

^a Gachon University   (South Korea)

^b Inha University School of Medicine   (South Korea)

Author keywords

Cancer prevention; Gastric cancer; Helicobacter pylori; Inflammation

Indexed keywords

CHEMOKINE; CYCLOOXYGENASE 2; GINSENG EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 8; JANUS KINASE 2; NIMESULIDE; REBAMIPIDE; STAT3 PROTEIN;

ANTIINFLAMMATORY ACTIVITY; ATROPHIC GASTRITIS; CANCER PREVENTION; CANCER SURVIVAL; CAUSAL ATTRIBUTION; CELL PROLIFERATION; DISEASE ASSOCIATION; GENETIC IDENTIFICATION; GENETIC LINKAGE; GENETIC TRANSCRIPTION; HELICOBACTER INFECTION; HOST SUSCEPTIBILITY; HUMAN; INFECTION CONTROL; NONHUMAN; PROTEIN PHOSPHORYLATION; REVIEW; STOMACH CANCER; STOMACH CARCINOGENESIS;

EID: 80053187486     PISSN: None     EISSN: 20726694     Source Type: Journal    
DOI: 10.3390/cancers3033018     Document Type: Review

References (40)

1. Jemal, A.; Bray, F.; Center, M.M.; Ferlay, J.; Ward, E.; Forman, D. Global cancer statistics. CA Cancer J. Clin. 2011, 61, 69-90.
2. Owen, R.J. Helicobacter-Species classification and identification. Br. Med. Bull. 1998, 54, 17-30.
3. Peek, R.M., Jr.; Blaser, M.J. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat. Rev. Cancer 2002, 2, 28-37.
4. Fukase, K.; Kato, M.; Kikuchi, S.; Inoue, K.; Uemura, N.; Okamoto, S.; Terao, S.; Amagai, K.; Hayashi, S.; Asaka, M. Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomized controlled trial. Lancet 2008, 372, 392-397.
5. Bodger, K.; Crabtree, J.E. Helicobacter pylori and gastric inflammation. Br. Med. Bull. 1998, 54, 139-150.
6. Hessey, S.J.; Spencer, J.; Wyatt, J.I.; Sobala, G.; Rathbone, B.J.; Axon, A.T.; Dixon, M.F. Bacterial adhesion and disease activity in Helicobacter associated chronic gastritis. Gut 1990, 31, 134-138.
7. Persson, C.; Canedo, P.; Machado, J.C.; El-Omar, E.M.; Forman, D. Polymorphisms in inflammatory response genes and their association with gastric cancer: A HuGE systematic review and meta-analyses. Am. J. Epidemiol.173, 259-270.
8. Zhao, C.; Lu, X.; Bu, X.; Zhang, N.; Wang, W. Involvement of tumor necrosis factor-alpha in the upregulation of CXCR4 expression in gastric cancer induced by Helicobacter pylori. BMC Cancer 2010, 10, 419.
9. El-Omar, E.M.; Rabkin, C.S.; Gammon, M.D.; Vaughan, T.L.; Risch, H.A.; Schoenberg, J.B.; Stanford, J.L.; Mayne, S.T.; Goedert, J.; Blot, W.J.; Fraumeni, J.F., Jr.; Chow, W.H. Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. Gastroenterology 2003, 124, 1193-1201.
10. Sugimoto, M.; Furuta, T.; Shirai, N.; Nakamura, A.; Xiao, F.; Kajimura, M.; Sugimura, H.; Hishida, A. Different effects of polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on development of peptic ulcer and gastric cancer. J. Gastroenterol. Hepatol. 2007, 22, 51-59.
11. Zhang, J.; Dou, C.; Song, Y.; Ji, C.; Gu, S.; Xie, Y.; Mao, Y. Polymorphisms of tumor necrosis factor-alpha are associated with increased susceptibility to gastric cancer: A meta-analysis. J. Hum. Genet. 2008, 53, 479-489.
12. Loh, M.; Koh, K.X.; Yeo, B.H.; Song, C.M.; Chia, K.S.; Zhu, F.; Yeoh, K.G.; Hill, J.; Iacopetta, B.; Soong, R. Meta-analysis of genetic polymorphisms and gastric cancer risk: Variability in associations according to race. Eur. J. Cancer 2009, 45, 2562-2568.
13. Gorouhi, F.; Islami, F.; Bahrami, H.; Kamangar, F. Tumour-necrosis factor-A polymorphisms and gastric cancer risk: A meta-analysis. Br. J. Cancer 2008, 98, 1443-1451.
14. Gupta, R.A.; Dubois, R.N. Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nat. Rev. Cancer 2001, 1, 11-21.
15. Chun, K.S.; Surh, Y.J. Signal transduction pathways regulating cyclooxygenase-2 expression: Potential molecular targets for chemoprevention. Biochem. Pharmacol. 2004, 68, 1089-1100.
16. Wroblewski, L.E.; Peek, R.M., Jr.; Wilson, K.T. Helicobacter pylori and gastric cancer: factors that modulate disease risk. Clin. Microbiol. Rev. 2010, 23, 713-739.
17. Kundu, J.K.; Surh, Y.J. Inflammation: gearing the journey to cancer. Mutat. Res. 2008, 659, 15-30.
18. Song, Z.J.; Gong, P.; Wu, Y.E. Relationship between the expression of iNOS, VEGF, tumor angiogenesis and gastric cancer. World J. Gastroenterol. 2002, 8, 591-595.
19. Ohtani, T.; Ishihara, K.; Atsumi, T.; Nishida, K.; Kaneko, Y.; Miyata, T.; Itoh, S.; Narimatsu, M.; Maeda, H.; Fukada, T.; Itoh, M.; Okano, H.; Hibi, M.; Hirano, T. Dissection of signaling cascades through gp130 in vivo: Reciprocal roles for STAT3- and SHP2-mediated signals in immune responses. Immunity 2000, 12, 95-105.
20. Tebbutt, N.C.; Giraud, A.S.; Inglese, M.; Jenkins, B.; Waring, P.; Clay, F.J.; Malki, S.; Alderman, B.M.; Grail, D.; Hollande, F.; Heath, J.K.; Ernst, M. Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice. Nat. Med. 2002, 8, 1089-1097.
21. Heinrich, P.C.; Behrmann, I.; Muller-Newen, G.; Schaper, F.; Graeve, L. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem. J. 1998, 334 (Pt 2), 297-314.
22. Taga, T.; Kishimoto, T. Gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol. 1997, 15, 797-819.
23. Lee, I.O.; Kim, J.H.; Choi, Y.J.; Pillinger, M.H.; Kim, S.Y.; Blaser, M.J.; Lee, Y.C. Helicobacter pylori CagA phosphorylation status determines the gp130-activated SHP2/ERK and JAK/STAT signal transduction pathways in gastric epithelial cells. J. Biol. Chem. 2010, 285, 16042-16050.
24. Di Bisceglie, A.M. Hepatitis C and hepatocellular carcinoma. Hepatology 1997, 26, 34S-38S.
25. Murphy, S.J.; Anderson, L.A.; Johnston, B.T.; Fitzpatrick, D.A.; Watson, P.R.; Monaghan, P.; Murray, L.J. Have patients with esophagitis got an increased risk of adenocarcinoma? Results from a population-based study. World J. Gastroenterol. 2005, 11, 7290-7295.
26. Peek, R.M., Jr.; Crabtree, J.E. Helicobacter infection and gastric neoplasia. J. Pathol. 2006, 208, 233-248.
27. Marx, J. Cancer research. Inflammation and cancer: the link grows stronger. Science 2004, 306, 966-968.
28. Hong, S.; Lee, H.J.; Kim, S.J.; Hahm, K.B. Connection between inflammation and carcinogenesis in gastrointestinal tract: focus on TGF-beta signaling. World J. Gastroenterol. 2010, 16, 2080-2093.
29. Tu, S.; Bhagat, G.; Cui, G.; Takaishi, S.; Kurt-Jones, E.A.; Rickman, B.; Betz, K.S.; Penz- Oesterreicher, M.; Bjorkdahl, O.; Fox, J.G.; Wang, T.C. Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell 2008, 14, 408-419.
30. McNamara, D.; El-Omar, E. Helicobacter pylori infection and the pathogenesis of gastric cancer: a paradigm for host-bacterial interactions. Dig. Liver Dis. 2008, 40, 504-509.
31. Nardone, G.; Rocco, A.; Malfertheiner, P. Review article: Helicobacter pylori and molecular events in precancerous gastric lesions. Aliment. Pharmacol. Ther. 2004, 20, 261-270.
32. Lee, D.H.; Hahm, K.B. Inflammatory cytokine gene polymorphisms and gastric cancer. J. Gastroenterol. Hepatol. 2008, 23, 1470-1472.
33. Han, S.U.; Kim, Y.B.; Joo, H.J.; Hahm, K.B.; Lee, W.H.; Cho, Y.K.; Kim, D.Y.; Kim, M.W. Helicobacter pylori infection promotes gastric carcinogenesis in a mice model. J. Gastroenterol. Hepatol. 2002, 17, 253-261.
34. Hahm, K.B.; Song, Y.J.; Oh, T.Y.; Lee, J.S.; Surh, Y.J.; Kim, Y.B.; Yoo, B.M.; Kim, J.H.; Han, S.U.; Nahm, K.T.; Kim, M.W.; Kim, D.Y.; Cho, S.W. Chemoprevention of Helicobacter pylori-associated gastric carcinogenesis in a mouse model: is it possible? J. Biochem. Mol. Biol. 2003, 36, 82-94.
35. Nam, K.T.; Hahm, K.B.; Oh, S.Y.; Yeo, M.; Han, S.U.; Ahn, B.; Kim, Y.B.; Kang, J.S.; Jang, D.D.; Yang, K.H.; Kim, D.Y. The selective cyclooxygenase-2 inhibitor nimesulide prevents Helicobacter pylori-associated gastric cancer development in a mouse model. Clin. Cancer Res. 2004, 10, 8105-8113.
36. Nam, K.T.; Oh, S.Y.; Ahn, B.; Kim, Y.B.; Jang, D.D.; Yang, K.H.; Hahm, K.B.; Kim, D.Y. Decreased Helicobacter pylori associated gastric carcinogenesis in mice lacking inducible nitric oxide synthase. Gut 2004, 53, 1250-1255.
37. Lee, K.M.; Yeo, M.; Choue, J.S.; Jin, J.H.; Park, S.J.; Cheong, J.Y.; Lee, K.J.; Kim, J.H.; Hahm, K.B. Protective mechanism of epigallocatechin-3-gallate against Helicobacter pylori-induced gastric epithelial cytotoxicity via the blockage of TLR-4 signaling. Helicobacter 2004, 9, 632-642.
38. Park, S.; Yeo, M.; Jin, J.H.; Lee, K.M.; Jung, J.Y.; Choue, R.; Cho, S.W.; Hahm, K.B. Rescue of Helicobacter pylori-induced cytotoxicity by red ginseng. Dig. Dis. Sci. 2005, 50, 1218-1227.
39. Lee, S.Y.; Shin, Y.W.; Hahm, K.B. Phytoceuticals: mighty but ignored weapons against Helicobacter pylori infection. J. Dig. Dis. 2008, 9, 129-139.
40. Won, I.; Kim, Y.J.; Kim, S.J.; Kim, E.H.; Hahm, K.B. Nutrigenomic approach to tackle the unpleasant journey to Helicobacter pylori-associated gastric carcinogenesis. J. Dig. Dis. 2011, 12, 157-164.