Insulin-like growth factor-2 (IGF2) loss of imprinting marks a field defect within human prostates containing cancer

Prostate

Volumn 71, Issue 15, 2011, Pages 1621-1630

  Bhusari, Sachin ^a   Yang, Bing ^a   Kueck, Jessica ^a   Huang, Wei ^a,b   Jarrard, David F ^a,b,c  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

field effect; H19; IGF2; prostate cancer

Indexed keywords

SOMATOMEDIN B;

ADULT; ARTICLE; CLINICAL ARTICLE; DNA METHYLATION; GENE EXPRESSION; GENOME IMPRINTING; HUMAN; HUMAN TISSUE; LOSS OF IMPRINTING; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTATE CANCER;

ADULT; AGED; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMIC IMPRINTING; GENOTYPE; HUMANS; INSULIN-LIKE GROWTH FACTOR II; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATE; PROSTATIC NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM; STATISTICS, NONPARAMETRIC;

EID: 80053180338     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.21379     Document Type: Article

References (54)

1. Slaughter DP, Southwick HW, Smejkal W,. Field cancerization in oral stratified squamous epithelium. Clinical implications of multicentric origin. Cancer 1953; 6 (5): 963-968.
2. Qian J, Wollan P, Bostwick DG,. The extent and multicentricity of high-grade prostatic intraepithelial neoplasia in clinically localized prostatic adenocarcinoma. Hum Pathol 1997; 28 (2): 143.
3. Epstein JI, Carmichael MJ, Partin AW, Walsh PC,. Small high grade adenocarcinoma of the prostate in radical prostatectomy specimens performed for nonpalpable disease: pathogenetic and clinical implications. J Urol 1994; 151 (6): 1587-1592. (Pubitemid 24151309)
4. De Marzo AM, Platz EA, Sutcliffe S, Xu J, Gronberg H, Drake CG, Nakai Y, Isaacs WB, Nelson WG,. Inflammation in prostate carcinogenesis. Nat Rev Canc 2007; 7 (4): 256.
5. Vukovic B, Park PC, Al-Maghrabi J, Beheshti B, Sweet J, Evans A, Trachenberg J, Squire JA,. Evidence of multifocality of telomere erosion in high-grade prostatic intraepithelial neoplasia (HPIN) and concurrent carcinoma. Oncogene 2003; 22 (13): 1978.
6. Larisa N, Vijayalakshmi A, Peter HG,. Evidence for field cancerization of the prostate. Prostate 2009; 69 (13): 1470-1479.
7. Yu H, Rohan T,. Role of the insulin-like growth factor family in cancer development and progression. J Natl Canc Inst 2000; 92 (18): 1472-1489.
8. Cohen P, Peehl DM, Baker B, Liu F, Hintz RL, Rosenfeld RG,. Insulin-like growth factor axis abnormalities in prostatic stromal cells from patients with benign prostatic hyperplasia. J Clin Endocrinol Metab 1994; 79 (5): 1410-1415. (Pubitemid 24369858)
9. Li S-L, Goko H, Xu Z-D, Kimura G, Sun Y, Kawachi MH, Wilson TG, Wilczynski S, Fujita-Yamaguchi Y,. Expression of insulin-like growth factor (IGF)-II in human prostate, breast, bladder, and paraganglioma tumors. Cell Tissue Res 1998; 291 (3): 469.
10. Rogler CE, Yang D, Rossetti L, Donohoe J, Alt E, Chang CJ, Rosenfeld R, Neely K, Hintz R,. Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice. J Biol Chem 1994; 269 (19): 13779-13784. (Pubitemid 24191120)
11. Lopez T, Hanahan D,. Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis. Cancer cell 2002; 1 (4): 339.
12. Ohlsson R, Hedborg F, Holmgren L, Walsh C, Ekstrom TJ,. Overlapping patterns of IGF2 and H19 expression during human development: biallelic IGF2 expression correlates with a lack of H19 expression. Development 1994; 120 (2): 361-368. (Pubitemid 24042403)
13. Phillips JE, Corces VG,. CTCF: master weaver of the genome. Cell 2009; 137 (7): 1194.
14. Cui H, Cruz-Correa M, Giardiello FM, Hutcheon DF, Kafonek DR, Brandenburg S, Wu Y, He X, Powe NR, Feinberg AP,. Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science 2003; 299 (5613): 1753-1755. (Pubitemid 36337205)
15. Ogawa O, Becroft DM, Morison IM, Eccles MR, Skeen JE, Mauger DC, Reeve AE,. Constitutional relaxation of insulin-like growth factor II gene imprinting associated with Wilms' tumour and gigantism. Nat Genets 1993; 5 (4): 408-412. (Pubitemid 23351315)
16. Zhao R, DeCoteau JF, Geyer CR, Gao M, Cui H, Casson AG,. Loss of imprinting of the insulin-like growth factor II (IGF2) gene in esophageal normal and adenocarcinoma tissues. Carcinogenesis 2009; 30 (12): 2117-2122.
17. Peter V, Heike W, Cornelia B, Bianka H, Uwe S, Uwe M,. Loss of imprinting of IGF-II gene in children with acute lymphoblastic leukemia. Leuk Res 2003; 27 (9): 807.
18. Jarrard DF, Bussemakers MJ, Bova GS, Isaacs WB,. Regional loss of imprinting of the insulin-like growth factor II gene occurs in human prostate tissues. Clin Canc Res 1995; 1 (12): 1471-1478. (Pubitemid 26028082)
19. Ling JQ, Li T, Hu JF, Vu TH, Chen HL, Qiu XW, Cherry AM, Hoffman AR,. CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1. Science 2006; 312 (5771): 269-272.
20. Sakatani T, Kaneda A, Iacobuzio-Donahue CA, Carter MG, de Boom Witzel S, Okano H, Ko MSH, Ohlsson R, Longo DL, Feinberg AP,. Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice. Science 2005; 307 (5717): 1976-1978. (Pubitemid 40404709)
21. Fu VX, Dobosy JR, Desotelle JA, Almassi N, Ewald JA, Srinivasan R, Berres M, Svaren J, Weindruch R, Jarrard DF,. Aging and cancer-related loss of insulin-like growth factor 2 imprinting in the mouse and human prostate. Canc Res 2008; 68 (16): 6797-6802.
22. Schwarze SR, Luo J, Isaacs WB, Jarrard DF,. Modulation of CXCL14 (BRAK) expression in prostate cancer. Prostate 2005; 64 (1): 67.
23. Bennett-Baker PE, Wilkowski J, Burke DT,. Age-associated activation of epigenetically repressed genes in the mouse. Genetics 2003; 165 (4): 2055-2062. (Pubitemid 38040289)
24. Murrell A, Ito Y, Verde G, Huddleston J, Woodfine K, Silengo MC, Spreafico F, Perotti D, De Crescenzo A, Sparago A, Cerrato F, Riccio A,. Distinct methylation changes at the IGF2-H19 locus in congenital growth disorders and cancer. PLoS ONE 2008; 3 (3): e1849.
25. Pant V, Mariano P, Kanduri C, Mattsson A, Lobanenkov V, Heuchel R, Ohlsson R,. The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domains. Gene Dev 2003; 17 (5): 586-590. (Pubitemid 36307542)
26. Li Y-M, Franklin G, Cui H-M, Svensson K, He X-B, Adam G, Ohlsson R, Pfeifer S,. The H19 transcript is associated with polysomes and may regulate IGF2 expression intrans. J Biol Chem 1998; 273 (43): 28247-28252. (Pubitemid 28496123)
27. Matouk IJ, DeGroot N, Mezan S, Ayesh S, Abu-Lail R, Hochberg A, Galun E,. The H19 non-coding RNA is essential for human tumor growth. PLoS One 2007; 2 (9): e845.
28. Bell AC, Felsenfeld G,. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature 2000; 405 (6785): 482.
29. Thorvaldsen JL, Duran KL, Bartolomei MS,. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and IGF2. Gene Dev 1998; 12 (23): 3693-3702. (Pubitemid 29019650)
30. Ravenel JD, Broman KW, Perlman EJ, Niemitz EL, Jayawardena TM, Bell DW, Haber DA, Uejima H, Feinberg AP,. Loss of imprinting of insulin-like growth factor-II (IGF2) gene in distinguishing specific biologic subtypes of Wilms tumor. J Natl Canc Inst 2001; 93 (22): 1698-1703. (Pubitemid 33130258)
31. Woodson K, Flood A, Green L, Tangrea JA, Hanson J, Cash B, Schatzkin A, Schoenfeld P,. Loss of insulin-like growth factor-II imprinting and the presence of screen-detected colorectal adenomas in women. J Natl Canc Inst 2004; 96 (5): 407-410. (Pubitemid 38351303)
32. Holmgren C, Kanduri C, Dell G, Ward A, Mukhopadhya R, Kanduri M, Lobanenkov V, Ohlsson R,. CpG methylation regulates the Igf2/H19 insulator. Curr Biol: CB 2001; 11 (14): 1128.
33. Rodolfo M, Lucilla D, Roberto P, Deborah T, Peter HB,. Subtle changes in benign tissue adjacent to prostate neoplasia detected with a Bayesian belief network. J Pathol 1997; 182 (4): 442-4449.
34. Mairinger T, Mikuz G, Gschwendtner A,. Nuclear chromatin texture analysis of nonmalignant tissue can detect adjacent prostatic adenocarcinoma. Prostate 1999; 41 (1): 12-19. (Pubitemid 29390411)
35. Veltri RW, Khan MA, Miller MC, Epstein JI, Mangold LA, Walsh PC, Partin AW,. Ability to predict metastasis based on pathology findings and alterations in nuclear structure of normal-appearing and cancer peripheral zone epithelium in the prostate. Clin Canc Res 2004; 10 (10): 3465-3473. (Pubitemid 38685454)
36. Jyoti M, Shobha V, Haiying W, Hsiling C, Janet V, Karen G, Raymond BN, Jaclyn RN, Abhijit M,. Quantitative, spatial resolution of the epigenetic field effect in prostate cancer. Prostate 2008; 68 (2): 152-160.
37. Hanson JA, Gillespie JW, Grover A, Tangrea MA, Chuaqui RF, Emmert-Buck MR, Tangrea JA, Libutti SK, Linehan WM, Woodson KG,. Gene promoter methylation in prostate tumor-associated stromal cells. J Natl Canc Inst 2006; 98 (4): 255-261. (Pubitemid 43264709)
38. Yu YP, Landsittel D, Jing L, Nelson J, Ren B, Liu L, McDonald C, Thomas R, Dhir R, Finkelstein S,. Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy. J Clin Oncol 2004; 22 (14): 2790.
39. Chandran UR, Dhir R, Ma C, Michalopoulos G, Becich M, Gilbertson J,. Differences in gene expression in prostate cancer, normal appearing prostate tissue adjacent to cancer and prostate tissue from cancer free organ donors. BMC Canc 2005; 5 (1): 45.
40. Ananthanarayanan V, Deaton RJ, Yang XJ, Pins MR, Gann PH,. Alteration of proliferation and apoptotic markers in normal and premalignant tissue associated with prostate cancer. BMC Canc 2006; 6 (1): 73.
41. Ananthanarayanan V, Deaton RJ, Yang XJ, Pins MR, Gann PH,. Alpha-methylacyl-CoA racemase (AMACR) expression in normal prostatic glands and high-grade prostatic intraepithelial neoplasia (HGPIN): association with diagnosis of prostate cancer. Prostate 2004; 63 (4): 341-3346.
42. Cohen P, Peehl DM, Lamson G, Rosenfeld RG,. Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins in primary cultures of prostate epithelial cells. J Clin Endocrinol Metab 1991; 73 (2): 401-407. (Pubitemid 21921888)
43. Cardillo MR, Monti S, Di Silverio F, Gentile V, Sciarra F, Toscano V,. Insulin-like growth factor (IGF)-I, IGF-II and IGF type I receptor (IGFR-I) expression in prostatic cancer. Anticanc Res 2003; 23 (5): 3825-3836.
44. Leighton PA, Ingram RS, Eggenschwiler J, Efstratiadis A, Tilghman SM,. Disruption of imprinting caused by deletion of the H19 gene region in mice. Nature 1995; 375 (6526): 34.
45. Ohlsson R, Renkawitz R, Lobanenkov V,. CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease. Trend Genet 2001; 17 (9): 520.
46. Reik W, Murrell A,. Genomic imprinting-silence across the border. Nature 2000; 405 (6785): 408-409.
47. Samani AA, Yakar S, LeRoith D, Brodt P,. The role of the IGF system in cancer growth and metastasis: overview and recent insights. Endocr Rev 2007; 28 (1): 20-47. (Pubitemid 46220849)
48. Hao Y, Crenshaw T, Moulton T, Newcomb E, Tycko B,. Tumour-suppressor activity of H19 RNA. Nature 1993; 365 (6448): 764.
49. Matouk I, Ohana P, Ayesh S, Sidi A, Czerniak A, de Groot N, Hochberg A,. The oncofetal H19 RNA in human cancer, from the bench to the patient. Canc Ther 2005; 3: 249-266.
50. Vu TH, Nguyen AH, Hoffman AR,. Loss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cells. Hum Mol Genet 2010; 19 (5): 901-919.
51. Baba Y, Nosho K, Shima K, Huttenhower C, Tanaka N, Hazra A, Giovannucci EL, Fuchs CS, Ogino S,. Hypomethylation of the insulin-like growth factor 2 differentially methylated region in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis. Gastroenterology 2010; 139 (6): 1855-1864.
52. Ekstrom TJ, Cui H, Li X, Ohlsson R,. Promoter-specific IGF2 imprinting status and its plasticity during human liver development. Development 1995; 121 (2): 309-316.
53. Feinberg AP, Ohlsson R, Henikoff S,. The epigenetic progenitor origin of human cancer. Nat Rev Genet 2006; 7 (1): 21.
54. Ito Y, Koessler T, Ibrahim AEK, Rai S, Vowler SL, Abu-Amero S, Silva AL, Maia AT, Huddleston JE, Uribe-Lewis S,. Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer. Hum Mol Genet 2008; 17 (17): 2633.