Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel

Molecular Cancer Therapeutics

Volumn 6, Issue 3, 2007, Pages 1167-1174

  Sarkaria, Jann N ^a   Yang, Lin ^a   Grogan, Patrick T ^a   Kitange, Gaspar J ^a   Carlson, Brett L ^a   Schroeder, Mark A ^a   Galanis, Evanthia ^a   Giannini, Caterina ^a   Wu, Wenting ^a   Dinca, Eduard B ^a   James, C David ^b  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ARGININE; COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; LEUCINE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; THREONINE;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; DRUG EFFICACY; DRUG SENSITIVITY; GENE AMPLIFICATION; GLIOBLASTOMA; HUMAN; HUMAN CELL; MISSENSE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; TUMOR XENOGRAFT; WILD TYPE;

ANIMALS; ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; GLIOBLASTOMA; HUMANS; MICE; MICE, NUDE; MUTATION; PROTEIN KINASE INHIBITORS; PTEN PHOSPHOHYDROLASE; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SURVIVAL RATE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 34147184365     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-06-0691     Document Type: Article

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