CYP5122A1, a novel cytochrome P450 is essential for survival of Leishmania donovani

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Verma, Smriti ^a   Mehta, Ashish ^a,b   Shaha, Chandrima ^a  

^a NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

^b DEPARTMENT OF CARDIOLOGY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ANTIMONY; CALCIUM ION; CYTOCHROME P450; CYTOCHROME P450 5122A1; ERGOSTEROL; MILTEFOSINE; NEOMYCIN; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; PROTOZOAL PROTEIN; REACTIVE OXYGEN METABOLITE;

ALLELE; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME LOCALIZATION; GLYCOSOME; HAMSTER; IN VITRO STUDY; IN VIVO STUDY; LEISHMANIA DONOVANI; MACROPHAGE; MASS FRAGMENTOGRAPHY; MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; PARASITE SURVIVAL; PHENOTYPE; PROMASTIGOTE; PROTEIN EXPRESSION; WILD TYPE; ANIMAL; CLASSIFICATION; DRUG EFFECT; GENETICS; GENOME; IMMUNOHISTOCHEMISTRY; METABOLISM; PARASITOLOGY; PATHOGENICITY; PHYLOGENY; POLYACRYLAMIDE GEL ELECTROPHORESIS; SYRIAN HAMSTER; VISCERAL LEISHMANIASIS; WESTERN BLOTTING;

CRICETINAE; LEISHMANIA DONOVANI;

ADENOSINE TRIPHOSPHATE; ANIMALS; BLOTTING, WESTERN; CRICETINAE; CYTOCHROME P-450 ENZYME SYSTEM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ERGOSTEROL; GENOME, PROTOZOAN; IMMUNOHISTOCHEMISTRY; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MESOCRICETUS; MITOCHONDRIA; PHYLOGENY; PROTOZOAN PROTEINS; REACTIVE OXYGEN SPECIES;

EID: 80053115223     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025273     Document Type: Article

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