Fire within the vessels: Interactions between blood cells and inflammatory vascular injury

Frontiers in Bioscience - Scholar

Volumn 3 S, Issue 3, 2011, Pages 1089-1100

  Nacher, Maria ^a   Hidalgo, Andes ^a  

^a CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

Author keywords

Adhesion; Erythrocyte; Inflammation; Integrin; Microdomains; Neutrophil; Platelet; Review; Selectin; Vascular Injury

Indexed keywords

ADENOSINE DIPHOSPHATE; CXCL1 CHEMOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FIBRONECTIN; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INTERCELLULAR ADHESION MOLECULE 1; P SELECTIN GLYCOPROTEIN LIGAND 1; PADGEM PROTEIN; THROMBOSPONDIN; TUMOR NECROSIS FACTOR ALPHA; VITRONECTIN; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD CELL; BLOOD VESSEL INJURY; CARDIOVASCULAR INFLAMMATION; CELL FUNCTION; CELL INTERACTION; CHRONIC INFLAMMATION; ENDOTHELIUM CELL; ERYTHROCYTE; HUMAN; IMMUNORECEPTOR TYROSINE BASED ACTIVATION MOTIF; INFLAMMATION; LEUKOCYTE; LEUKOCYTE ACTIVATION; LYMPH NODE; MACROPHAGE; MICROVASCULATURE; MOLECULAR INTERACTION; MONOCYTE; NEUTROPHIL; NONHUMAN; POLYMERIZATION; RESPIRATORY BURST; SIGNAL TRANSDUCTION; STEADY STATE; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; TRANSFUSION RELATED ACUTE LUNG INJURY; VASCULAR ENDOTHELIUM; BIOLOGICAL MODEL; CARDIOVASCULAR DISEASE; CELL AGGREGATION; IMMUNOLOGY; PHYSIOLOGY; REVIEW;

BLOOD PLATELETS; CARDIOVASCULAR DISEASES; CELL AGGREGATION; ERYTHROCYTES; HUMANS; INFLAMMATION; MODELS, BIOLOGICAL; NEUTROPHILS; VASCULAR SYSTEM INJURIES;

EID: 80053113811     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: None     Document Type: Article

References (120)

1. R. Medzhitov: Origin and physiological roles of inflammation. Nature, 454(7203), 428-35 (2008)
2. A. Etzioni: Genetic etiologies of leukocyte adhesion defects. Curr Opin Immunol, 21(5), 481-6 (2009)
3. G. A. Diaz: CXCR4 mutations in WHIM syndrome: a misguided immune system? Immunol Rev, 203, 235-43 (2005) (Pubitemid 40179704)
4. F. Liu, H. Y. Wu, R. Wesselschmidt, T. Kornaga and D. C. Link: Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice. Immunity, 5(5), 491-501 (1996) (Pubitemid 26423476)
5. J. Palmblad and H. A. Papadaki: Chronic idiopathic neutropenias and severe congenital neutropenia. Curr Opin Hematol, 15(1), 8-14 (2008) (Pubitemid 350191023)
6. S. D. Rosenzweig and S. M. Holland: Phagocyte immunodeficienciesand their infections. J Allergy Clin Immunol, 113(4), 620-6 (2004)
7. Q. Ren, S. Ye and S. W. Whiteheart: The platelet release reaction: just when you thought platelet secretion was simple. Curr Opin Hematol, 15(5), 537-41 (2008)
8. A. Zarbock, R. K. Polanowska-Grabowska and K. Ley: Platelet-neutrophil- interactions: linking hemostasis and inflammation. Blood Rev, 21(2), 99-111 (2007) (Pubitemid 46428465)
9. J. W. Semple and J. Freedman: Platelets and innate immunity. Cell Mol Life Sci, 67(4), 499-511 (2010)
10. T. G. Diacovo, M. D. Catalina, M. H. Siegelman and U. H. von Andrian: Circulating activated platelets reconstitute lymphocyte homing and immunity in L-selectin-deficient mice. J Exp Med, 187(2), 197-204 (1998) (Pubitemid 28060435)
11. T. G. Diacovo, K. D. Puri, R. A. Warnock, T. A. Springer and U. H. von Andrian: Platelet-mediated lymphocyte delivery to high endothelial venules. Science, 273(5272), 252-5 (1996) (Pubitemid 26285894)
12. B. J. McMorran, V. M. Marshall, C. de Graaf, K. E. Drysdale, M. Shabbar, G. K. Smyth, J. E. Corbin, W. S. Alexander and S. J. Foote: Platelets kill intraerythrocytic malarial parasites and mediate survival to infection. Science, 323(5915), 797-800 (2009)
13. S. R. Clark, A. C. Ma, S. A. Tavener, B. McDonald, Z. Goodarzi, M. M. Kelly, K. D. Patel, S. Chakrabarti, E. McAvoy, G. D. Sinclair, E. M. Keys, E. Allen-Vercoe, R. Devinney, C. J. Doig, F. H. Green and P. Kubes: Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med, 13(4), 463-9 (2007) (Pubitemid 46559832)
14. World-Health-Organization: http://www.who.int/whosis/whostat/en/. In, (2008)
15. O. Soehnlein and L. Lindbom: Phagocyte partnership during the onset and resolution of inflammation. Nat Rev Immunol, 10(6), 427-39
16. D. D. Wagner and P. S. Frenette: The vessel wall and its interactions. Blood, 111(11), 5271-81 (2008)
17. C. Auffray, D. Fogg, M. Garfa, G. Elain, O. Join-Lambert, S. Kayal, S. Sarnacki, A. Cumano, G. Lauvau and F. Geissmann: Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior. Science, 317(5838), 666-70 (2007) (Pubitemid 47229966)
18. A. Zarbock and K. Ley: Neutrophil adhesion and activation under flow. Microcirculation, 16(1), 31-42 (2009)
19. R. P. McEver and C. Zhu: Rolling Cell Adhesion. Annu Rev Cell Dev Biol (2010)
20. J. Yang, T. Hirata, K. Croce, G. Merrill-Skoloff, B. Tchernychev, E. Williams, R. Flaumenhaft, B. C. Furie and B. Furie: Targeted gene disruption demonstrates that P-selectin glycoprotein ligand 1 (PSGL-1) is required for P-selectinmediated but not E- selectin-mediated neutrophil rolling and migration. J Exp Med, 190(12), 1769-82. (1999) (Pubitemid 30013843)
21. K. Ley, M. Allietta, D. C. Bullard and S. Morgan: Importance of E-selectin for firm leukocyte adhesion in vivo. Circ Res, 83(3), 287-94. (1998) (Pubitemid 28371318)
22. A. Zarbock, C. A. Lowell and K. Ley: Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1. Immunity, 26(6), 773-83 (2007) (Pubitemid 46907666)
23. A. Hidalgo, A. J. Peired, M. K. Wild, D. Vestweber and P. S. Frenette: Complete identification of E-selectin ligands on neutrophils reveals distinct functions of PSGL-1, ESL-1, and CD44. Immunity, 26(4), 477-89 (2007) (Pubitemid 46603003)
24. Y. Katayama, A. Hidalgo, J. Chang, A. Peired and P. S. Frenette: CD44 is a physiological E-selectin ligand on neutrophils. J Exp Med, 201(8), 1183-9 (2005) (Pubitemid 40637228)
25. R. Alon, T. Feizi, C. T. Yuen, R. C. Fuhlbrigge and T. A. Springer: Glycolipid ligands for selectins support leukocyte tethering and rolling under physiologic flow conditions. J Immunol, 154(10), 5356-66 (1995)
26. M. Matsumoto, K. Atarashi, E. Umemoto, Y. Furukawa, A. Shigeta, M. Miyasaka and T. Hirata: CD43 functions as a ligand for E-Selectin on activated T cells. J Immunol, 175(12), 8042-50 (2005) (Pubitemid 41798366)
27. L. Nimrichter, M. M. Burdick, K. Aoki, W. Laroy, M. A. Fierro, S. A. Hudson, C. E. Von Seggern, R. J. Cotter, B. S. Bochner, M. Tiemeyer, K. Konstantopoulos and R. L. Schnaar: E-selectin receptors on human leukocytes. Blood, 112(9), 3744-52 (2008)
28. T. Yago, J. Fu, J. M. McDaniel, J. J. Miner, R. P. McEver and L. Xia: Core 1-derived O-glycans are essential E-selectin ligands on neutrophils. Proc Natl Acad Sci U S A, 107(20), 9204-9 (2010)
29. V. Evangelista, S. Manarini, B. S. Coller and S. S. Smyth: Role of P-selectin, beta2-integrins, and Src tyrosine kinases in mouse neutrophil-platelet adhesion. J Thromb Haemost, 1(5), 1048-54 (2003)
30. Y. Q. Ma, E. F. Plow and J. G. Geng: P-selectin binding to P-selectin glycoprotein ligand -1 induces an intermediate state of alphaMbeta2 activation and acts cooperatively with extracellular stimuli to support maximal adhesion of human neutrophils. Blood, 104(8), 2549-56 (2004) (Pubitemid 39331860)
31. H. B. Wang, J. T. Wang, L. Zhang, Z. H. Geng, W. L. Xu, T. Xu, Y. Huo, X. Zhu, E. F. Plow, M. Chen and J. G. Geng: P-selectin primes leukocyte integrin activation during inflammation. Nat Immunol, 8(8), 882-92 (2007) (Pubitemid 47099040)
32. T. Yago, B. Shao, J. J. Miner, L. Yao, A. G. Klopocki, K. Maeda, K. M. Coggeshall and R. P. McEver: E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin alphaLbeta2-mediated slow leukocyte rolling. Blood, 116(3), 485-94 (2010)
33. A. Zarbock, C. L. Abram, M. Hundt, A. Altman, C. A. Lowell and K. Ley: PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling. J Exp Med, 205(10), 2339-47 (2008)
34. A. Hidalgo, J. Chang, J. E. Jang, A. J. Peired, E. Y. Chiang and P. S. Frenette: Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury. Nat Med, 15(4), 384-91 (2009)
35. J. Lee, G. Cacalano, T. Camerato, K. Toy, M. W. Moore and W. I. Wood: Chemokine binding and activities mediated by the mouse IL-8 receptor. J Immunol, 155(4), 2158-64 (1995)
36. S. J. Morgan, M. W. Moore, G. Cacalano and K. Ley: Reduced leukocyte adhesion response and absence of slow leukocyte rolling in interleukin-8 receptor-deficient mice. Microvasc Res, 54(2), 188-91 (1997) (Pubitemid 27433632)
37. A. Zarbock and K. Ley: Mechanisms and consequences of neutrophil interaction with the endothelium. Am J Pathol, 172(1), 1-7 (2008) (Pubitemid 351186361)
38. E. Y. Chiang, A. Hidalgo, J. Chang and P. S. Frenette: Imaging receptor microdomains on leukocyte subsets in live mice. Nat Methods, 4(3), 219-22 (2007) (Pubitemid 46358870)
39. M. Phillipson, B. Heit, P. Colarusso, L. Liu, C. M. Ballantyne and P. Kubes: Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade. J Exp Med, 203(12), 2569-75 (2006) (Pubitemid 44833334)
40. A. R. Schenkel, Z. Mamdouh and W. A. Muller: Locomotion of monocytes on endothelium is a critical step during extravasation. Nat Immunol, 5(4), 393-400 (2004) (Pubitemid 38500088)
41. V. Evangelista, Z. Pamuklar, A. Piccoli, S. Manarini, G. Dell'elba, R. Pecce, N. Martelli, L. Federico, M. Rojas, G. Berton, C. A. Lowell, L. Totani and S. S. Smyth: Src family kinases mediate neutrophil adhesion to adherent platelets. Blood, 109(6), 2461-9 (2007) (Pubitemid 46425889)
42. S. P. Jackson: The growing complexity of platelet aggregation. Blood, 109(12), 5087-95 (2007) (Pubitemid 46890522)
43. H. F. Langer and T. Chavakis: Leukocyte-endothelial interactions in inflammation. J Cell Mol Med, 13(7), 1211-20 (2009)
44. R. P. McEver: Adhesive interactions of leukocytes, platelets, and the vessel wall during hemostasis and inflammation. Thromb Haemost, 86(3), 746-56 (2001) (Pubitemid 32834182)
45. W. S. Nesbitt, S. Kulkarni, S. Giuliano, I. Goncalves, S. M. Dopheide, C. L. Yap, I. S. Harper, H. H. Salem and S. P. Jackson: Distinct glycoprotein Ib/V/IX and integrin alpha IIbbeta 3-dependent calcium signals cooperatively regulate platelet adhesion under flow. J Biol Chem, 277(4), 2965-72 (2002) (Pubitemid 34953332)
46. B. Savage, S. J. Shattil and Z. M. Ruggeri: Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor. J Biol Chem, 267(16), 11300-6 (1992)
47. B. Savage, E. Saldivar and Z. M. Ruggeri: Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell, 84(2), 289-97 (1996) (Pubitemid 26040846)
48. D. Kirchhofer, T. B. Tschopp, B. Steiner and H. R. Baumgartner: Role of collagen-adherent platelets in mediating fibrin formation in flowing whole blood. Blood, 86(10), 3815-22 (1995)
49. D. Patel, H. Vaananen, M. Jirouskova, T. Hoffmann, C. Bodian and B. S. Coller: Dynamics of GPIIb/IIIa-mediated platelet-platelet interactions in platelet adhesion/thrombus formation on collagen in vitro as revealed by videomicroscopy. Blood, 101(3), 929-36 (2003) (Pubitemid 36139361)
50. P. S. Frenette, R. C. Johnson, R. O. Hynes and D. D. Wagner: Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. Proc Natl Acad Sci U S A, 92(16), 7450-4 (1995)
51. P. Andre, C. V. Denis, J. Ware, S. Saffaripour, R. O. Hynes, Z. M. Ruggeri and D. D. Wagner: Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. Blood, 96(10), 3322-8 (2000)
52. P. S. Frenette, C. V. Denis, L. Weiss, K. Jurk, S. Subbarao, B. Kehrel, J. H. Hartwig, D. Vestweber and D. D. Wagner: P-Selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo. J Exp Med, 191(8), 1413-22 (2000) (Pubitemid 30227127)
53. G. G. Levy, W. C. Nichols, E. C. Lian, T. Foroud, J. N. McClintick, B. M. McGee, A. Y. Yang, D. R. Siemieniak, K. R. Stark, R. Gruppo, R. Sarode, S. B. Shurin, V. Chandrasekaran, S. P. Stabler, H. Sabio, E. E. Bouhassira, J. D. Upshaw, Jr., D. Ginsburg and H. M. Tsai: Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature, 413(6855), 488-94 (2001) (Pubitemid 32938741)
54. D. G. Motto, A. K. Chauhan, G. Zhu, J. Homeister, C. B. Lamb, K. C. Desch, W. Zhang, H. M. Tsai, D. D. Wagner and D. Ginsburg: Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice. J Clin Invest, 115(10), 2752-61 (2005) (Pubitemid 41434402)
55. J. Yip, Y. Shen, M. C. Berndt and R. K. Andrews: Primary platelet adhesion receptors. IUBMB Life, 57(2), 103-8 (2005) (Pubitemid 40632300)
56. S. Massberg, M. Gawaz, S. Gruner, V. Schulte, I. Konrad, D. Zohlnhofer, U. Heinzmann and B. Nieswandt: A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo. J Exp Med, 197(1), 41-9 (2003) (Pubitemid 36110256)
57. S. Massberg, I. Konrad, A. Bultmann, C. Schulz, G. Munch, M. Peluso, M. Lorenz, S. Schneider, F. Besta, I. Muller, B. Hu, H. L anger, E. Kremmer, M. Rudelius, U. Heinzmann, M. Ungerer and M. Gawaz: Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo. FASEB J, 18(2), 397-9 (2004)
58. D. D. Wagner and P. C. Burger: Platelets in inflammation and thrombosis. Arterioscler Thromb Vasc Biol, 23(12), 2131-7 (2003) (Pubitemid 37532311)
59. D. R. Phillips, I. F. Charo and R. M. Scarborough: GPIIb-IIIa: the responsive integrin. Cell, 65(3), 359-62 (1991) (Pubitemid 121002044)
60. S. J. Shattil and M. H. Ginsberg: Perspectives series: cell adhesion in vascular biology. Integrin signaling in vascular biology. J Clin Invest, 100(1), 1-5 (1997)
61. S. M. Buttrum, R. Hatton and G. B. Nash: Selectinmediated rolling of neutrophils on immobilized platelets. Blood, 82(4), 1165-74 (1993) (Pubitemid 23253990)
62. T. G. Diacovo, S. J. Roth, J. M. Buccola, D. F. Bainton and T. A. Springer: Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18. Blood, 88(1), 146-57 (1996) (Pubitemid 26230682)
63. H. M. Rinder, J. L. Bonan, C. S. Rinder, K. A. Ault and B. R. Smith: Dynamics of leukocyte-platelet adhesion in whole blood. Blood, 78(7), 1730-7 (1991)
64. Y. Huo, A. Schober, S. B. Forlow, D. F. Smith, M. C. Hyman, S. Jung, D. R. Littman, C. Weber and K. Ley: Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E. Nat Med, 9(1), 61-7 (2003) (Pubitemid 36098261)
65. K. Daub, H. Langer, P. Seizer, K. Stellos, A. E. May, P. Goyal, B. Bigalke, T. Schonberger, T. Geisler, D. Siegel-Axel, R. A. Oostendorp, S. Lindemann and M. Gawaz: Platelets induce differentiation of human CD34+ progenitor cells into foam cells and endothelial cells. FASEB J, 20(14), 2559-61 (2006)
66. K. Stellos, S. Gnerlich, B. Kraemer, S. Lindemann and M. Gawaz: Platelet interaction with progenitor cells: vascular regeneration or inquiry? Pharmacol Rep, 60(1), 101-8 (2008) (Pubitemid 351586548)
67. H. F. Langer, B. Bigalke, P. Seizer, K. Stellos, S. Fateh-Moghadam and M. Gawaz: Interaction of platelets and inflammatory endothelium in the development and progression of coronary artery disease. Semin Thromb Hemost, 36(2), 131-8 (2010)
68. N. Li, Q. Ji and P. Hjemdahl: Platelet-lymphocyte conjugation differs between lymphocyte subpopulations. J Thromb Haemost, 4(4), 874-81 (2006)
69. S. Massberg, I. Konrad, K. Schurzinger, M. Lorenz, S. Schneider, D. Zohlnhoefer, K. Hoppe, M. Schiemann, E. Kennerknecht, S. Sauer, C. Schulz, S. Kerstan, M. Rudelius, S. Seidl, F. Sorge, H. Langer, M. Peluso, P. Goyal, D. Vestweber, N. R. Emambokus, D. H. Busch, J. Frampton and M. Gawaz: Platelets secrete stromal cellderived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo. J Exp Med, 203(5), 1221-33 (2006) (Pubitemid 43736592)
70. A. Janowska-Wieczorek, M. Majka, J. Kijowski, M. Baj-Krzyworzeka, R. Reca, A. R. Turner, J. Ratajczak, S. G. Emerson, M. A. Kowalska and M. Z. Ratajczak: Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment. Blood, 98(10), 3143-9 (2001)
71. O. Barreiro, H. de la Fuente, M. Mittelbrunn and F. Sanchez-Madrid: Functional insights on the polarized redistribution of leukocyte integrins and their ligands during leukocyte migration and immune interactions. Immunol Rev, 218, 147-64 (2007) (Pubitemid 47052299)
72. T. Kinashi: Intracellular signalling controlling integrin activation in lymphocytes. Nat Rev Immunol, 5(7), 546-59 (2005) (Pubitemid 40961332)
73. A. J. Ridley, M. A. Schwartz, K. Burridge, R. A. Firtel, M. H. Ginsberg, G. Borisy, J. T. Parsons and A. R. Horwitz: Cell migration: integrating signals from front to back. Science, 302(5651), 1704-9 (2003) (Pubitemid 37505725)
74. M. D. Filippi, C. E. Harris, J. Meller, Y. Gu, Y. Zheng and D. A. Williams: Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils. Nat Immunol, 5(7), 744-51 (2004) (Pubitemid 39023307)
75. M. D. Filippi, K. Szczur, C. E. Harris and P. Y. Berclaz: Rho GTPase Rac1 is critical for neutrophil migration into the lung. Blood, 109(3), 1257-64 (2007) (Pubitemid 46220678)
76. K. Katagiri, A. Maeda, M. Shimonaka and T. Kinashi: RAPL, a Rap1-binding molecule that mediates Rap1- induced adhesion through spatial regulation of LFA-1. Nat Immunol, 4(8), 741-8 (2003) (Pubitemid 36986757)
77. K. Szczur, H. Xu, S. Atkinson, Y. Zheng and M. D. Filippi: Rho GTPase CDC42 regulates directionality and random movement via distinct MAPK pathways in neutrophils. Blood, 108(13), 4205-13 (2006) (Pubitemid 44913295)
78. Y. Kunisaki, A. Nishikimi, Y. Tanaka, R. Takii, M. Noda, A. Inayoshi, K. Watanabe, F. Sanematsu, T. Sasazuki, T. Sasaki and Y. Fukui: DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis. J Cell Biol, 174(5), 647-52 (2006)
79. A. Nishikimi, H. Fukuhara, W. Su, T. Hongu, S. Takasuga, H. Mihara, Q. Cao, F. Sanematsu, M. Kanai, H. Hasegawa, Y. Tanaka, M. Shibasaki, Y. Kanaho, T. Sasaki, M. A. Frohman and Y. Fukui: Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis. Science, 324(5925), 384-7 (2009)
80. J. H. Lee, T. Katakai, T. Hara, H. Gonda, M. Sugai and A. Shimizu: Roles of p-ERM and Rho-ROCK signaling in lymphocyte polarity and uropod formation. J Cell Biol, 167(2), 327-37 (2004) (Pubitemid 39435075)
81. B. Heit, S. M. Robbins, C. M. Downey, Z. Guan, P. Colarusso, B. J. Miller, F. R. Jirik and P. Kubes: PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils. Nat Immunol, 9(7), 743-52 (2008) (Pubitemid 351859157)
82. J. L. Alonso-Lebrero, J. M. Serrador, C. Dominguez-Jimenez, O. Barreiro, A. Luque, M. A. del Pozo, K. Snapp, G. Kansas, R. Schwartz-Albiez, H. Furthmayr, F. Lozano and F. Sanchez-Madrid: Polarization and interaction of adhesion molecules P-selectin glycoprotein ligand 1 and intercellular adhesion molecule 3 with moesin and ezrin in myeloid cells. Blood, 95(7), 2413-9 (2000) (Pubitemid 30167744)
83. M. Nieto, J. M. Frade, D. Sancho, M. Mellado, A. C. Martinez and F. Sanchez-Madrid: Polarization of chemokine receptors to the leading edge during lymphocyte chemotaxis. J Exp Med, 186(1), 153-8 (1997) (Pubitemid 27304858)
84. S. I. Simon, Y. Hu, D. Vestweber and C. W. Smith: Neutrophil tethering on E-selectin activates beta 2 integrin binding to ICAM-1 through a mitogen-activated protein kinase signal transduction pathway. J Immunol, 164(8), 4348-58 (2000) (Pubitemid 30215098)
85. A. Turhan, L. A. Weiss, N. Mohandas, B. S. Coller and P. S. Frenette: Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm. Proc Natl Acad Sci U S A, 99(5), 3047-51 (2002) (Pubitemid 34240583)
86. M. Sperandio, M. L. Smith, S. B. Forlow, T. S. Olson, L. Xia, R. P. McEver and K. Ley: P-selectin glycoprotein ligand-1 mediates L-selectin-dependent leukocyte rolling in venules. J Exp Med, 197(10), 1355-63 (2003) (Pubitemid 36617782)
87. V. Evangelista, S. Manarini, S. Rotondo, N. Martelli, R. Polischuk, J. L. McGregor, G. de Gaetano and C. Cerletti: Platelet/polymorphonuclear leukocyte interaction in dynamic conditions: evidence of adhesion cascade and cross talk between P-selectin and the beta 2 integrin CD11b/CD18. Blood, 88(11), 4183-94 (1996) (Pubitemid 26399164)
88. T. Palabrica, R. Lobb, B. C. Furie, M. Aronovitz, C. Benjamin, Y. M. Hsu, S. A. Sajer and B. Furie: Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets. Nature, 359(6398), 848-51 (1992)
89. Y. Wang, M. Sakuma, Z. Chen, V. Ustinov, C. Shi, K. Croce, A. C. Zago, J. Lopez, P. Andre, E. Plow and D. I. Simon: Leukocyte engagement of platelet glycoprotein Ibalpha via the integrin Mac-1 is critical for the biological response to vascular injury. Circulation, 112(19), 2993-3000 (2005) (Pubitemid 41612303)
90. N. Maugeri, P. Rovere-Querini, V. Evangelista, C. Covino, A. Capobianco, M. T. Bertilaccio, A. Piccoli, L. Totani, D. Cianflone, A. Maseri and A. A. Manfredi: Neutrophils phagocytose activated platelets in vivo: a phosphatidylserine, P-selectin, and {beta}2 integrindependent cell clearance program. Blood, 113(21), 5254-65 (2009)
91. M. R. Looney, B. M. Gilliss and M. A. Matthay: Pathophysiology of transfusion-related acute lung injury. Curr Opin Hematol, 17(5), 418-23 (2010)
92. M. R. Looney, J. X. Nguyen, Y. Hu, J. A. Van Ziffle, C. A. Lowell and M. A. Matthay: Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury. J Clin Invest, 119(11), 3450-61 (2009)
93. A. Ruf and H. Patscheke: Platelet-induced neutrophil activation: platelet-expressed fibrinogen induces the oxidative burst in neutrophils by an interaction with CD11C/CD18. Br J Haematol, 90(4), 791-6 (1995)
94. A. Ruf, R. F. Schlenk, A. Maras, E. Morgenstern and H. Patscheke: Contact-induced neutrophil activation by platelets in human cell suspensions and whole blood. Blood, 80(5), 1238-46 (1992)
95. A. Zarbock, K. Singbartl and K. Ley: Complete reversal of acid-induced acute lung injury by blocking of plateletneutrophil aggregation. J Clin Invest, 116(12), 3211-9 (2006) (Pubitemid 44878635)
96. R. C. Bone: The pathogenesis of sepsis. Ann Intern Med, 115(6), 457-69 (1991)
97. V. Brinkmann, U. Reichard, C. Goosmann, B. Fauler, Y. Uhlemann, D. S. Weiss, Y. Weinrauch and A. Zychlinsky: Neutrophil extracellular traps kill bacteria. Science, 303(5663), 1532-5 (2004) (Pubitemid 38314426)
98. M. A. Gakidis, X. Cullere, T. Olson, J. L. Wilsbacher, B. Zhang, S. L. Moores, K. Ley, W. Swat, T. Mayadas and J. S. Brugge: Vav GEFs are required for beta2 integrindependent functions of neutrophils. J Cell Biol, 166(2), 273-82 (2004) (Pubitemid 38988779)
99. M. Moser, M. Bauer, S. Schmid, R. Ruppert, S. Schmidt, M. Sixt, H. V. Wang, M. Sperandio and R. Fassler: Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells. Nat Med, 15(3), 300-5 (2009)
100. M. S. Goel and S. L. Diamond: Adhesion of normal erythrocytes at depressed venous shear rates to activated neutrophils, activated platelets, and fibrin polymerized from plasma. Blood, 100(10), 3797-803 (2002) (Pubitemid 35303954)
101. P. Hermand, M. Huet, I. Callebaut, P. Gane, E. Ihanus, C. G. Gahmberg, J. P. Cartron and P. Bailly: Binding sites of leukocyte beta 2 integrins (LFA-1, Mac-1) on the human ICAM-4/LW blood group protein. J Biol Chem, 275(34), 26002-10 (2000)
102. P. S. Frenette: Sickle cell vasoocclusion: heterotypic, multicellular aggregations driven by leukocyte adhesion. Microcirculation, 11(2), 167-77 (2004) (Pubitemid 39619077)
103. O. S. Platt: Sickle cell anemia as an inflammatory disease. J Clin Invest, 106(3), 337-8 (2000) (Pubitemid 30655633)
104. P. S. Frenette and G. F. Atweh: Sickle cell disease: old discoveries, new concepts, and future promise. J Clin Invest, 117(4), 850-8 (2007) (Pubitemid 46556737)
105. R. H. Wang, G. Phillips, Jr., M. E. Medof and C. Mold: Activation of the alternative complement pathway by exposure of phosphatidylethanolamine and phosphatidylserine on erythrocytes from sickle cell disease patients. J Clin Invest, 92(3), 1326-35 (1993) (Pubitemid 23273908)
106. J. Chang, J. T. Patton, A. Sarkar, B. Ernst, J. L. Magnani and P. S. Frenette: GMI-1070, a novel panselectin antagonist, reverses acute vascular occlusions in sickle cell mice. Blood, 116(10), 1779-86 (2010)
107. B. S. Coller: Leukocytosis and ischemic vascular disease morbidity and mortality: is it time to intervene? Arterioscler Thromb Vasc Biol, 25(4), 658-70 (2005) (Pubitemid 40463851)
108. E. Galkina and K. Ley: Immune and inflammatory mechanisms of atherosclerosis (*). Annu Rev Immunol, 27, 165-97 (2009)
109. K. J. Woollard and F. Geissmann: Monocytes in atherosclerosis: subsets and functions. Nat Rev Cardiol, 7(2), 77-86 (2010)
110. L. McGregor, J. Martin and J. L. McGregor: Plateletleukocyte aggregates and derived microparticles in inflammation, vascular remodelling and thrombosis. Front Biosci, 11, 830-7 (2006) (Pubitemid 43258184)
111. R. Mazor, R. Shurtz-Swirski, R. Farah, B. Kristal, G. Shapiro, F. Dorlechter, M. Cohen-Mazor, E. Meilin, S. Tamara and S. Sela: Primed polymorphonuclear leukocytes constitute a possible link between inflammation and oxidative stress in hyperlipidemic patients. Atherosclerosis, 197(2), 937-43 (2008) (Pubitemid 351417898)
112. P. Rotzius, S. Thams, O. Soehnlein, E. Kenne, C. N. Tseng, N. K. Bjorkstrom, K. J. Malmberg, L. Lindbom and E. E. Eriksson: Distinct infiltration of neutrophils in lesion shoulders in ApoE-/- mice. Am J Pathol, 177(1), 493-500 (2010)
113. L. Yvan-Charvet, C. Welch, T. A. Pagler, M. Ranalletta, M. Lamkanfi, S. Han, M. Ishibashi, R. Li, N. Wang and A. R. Tall: Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increasedsignaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions. Circulation, 118(18), 1837-47 (2008)
114. A. Zernecke, I. Bot, Y. Djalali-Talab, E. Shagdarsuren, K. Bidzhekov, S. Meiler, R. Krohn, A. Schober, M. Sperandio, O. Soehnlein, J. Bornemann, F. Tacke, E. A. Biessen and C. Weber: Protective role of CXC receptor 4/CXC ligand 12 unveils the importance of neutrophils in atherosclerosis. Circ Res, 102(2), 209-17 (2008) (Pubitemid 351651125)
115. M. J. Davies, J. L. Gordon, A. J. Gearing, R. Pigott, N. Woolf, D. Katz and A. Kyriakopoulos: The expression of the adhesion molecules ICAM-1, VCAM-1, PECAM, and E-selectin in human atherosclerosis. J Pathol, 171(3), 223-9 (1993) (Pubitemid 23345967)
116. R. G. Collins, R. Velji, N. V. Guevara, M. J. Hicks, L. Chan and A. L. Beaudet: P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein Edeficient mice. J Exp Med, 191(1), 189-94 (2000) (Pubitemid 30043660)
117. Z. M. Dong, S. M. Chapman, A. A. Brown, P. S. Frenette, R. O. Hynes and D. D. Wagner: The combined role of P- and E-selectins in atherosclerosis. J Clin Invest, 102(1), 145-52 (1998) (Pubitemid 28323841)
118. P. C. Burger and D. D. Wagner: Platelet P-selectin facilitates atherosclerotic lesion development. Blood, 101(7), 2661-6 (2003) (Pubitemid 36857627)
119. Y. Huo and K. Ley: Adhesion molecules and atherogenesis. Acta Physiol Scand, 173(1), 35-43 (2001) (Pubitemid 32948331)
120. M. F. Nageh, E. T. Sandberg, K. R. Marotti, A. H. Lin, E. P. Melchior, D. C. Bullard and A. L. Beaudet: Deficiency of inflammatory cell adhesion molecules protects against atherosclerosis in mice. Arterioscler Thromb Vasc Biol, 17(8), 1517-20 (1997) (Pubitemid 27387771)