Whole body hypothermia broadens the therapeutic window of intranasally administered IGF-1 in a neonatal rat model of cerebral hypoxia-ischemia

Brain Research

Volumn 1385, Issue , 2011, Pages 246-256

  Lin, Shuying ^a   Rhodes, Philip G ^a   Cai, Zhengwei ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Hypothermia; IGF 1; Intranasal administration; Neonatal hypoxia ischemia; NF B; Polymorphonuclear cell infiltration

Indexed keywords

SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN HYPOXIA; BRAIN ISCHEMIA; CAROTID ARTERY LIGATION; CELL ACTIVATION; CELL INFILTRATION; COMMON CAROTID ARTERY; CONTROLLED STUDY; HYPOTHERMIA; LEUKOCYTE COUNT; MICROGLIA; NEUROPROTECTION; NEWBORN; NONHUMAN; OXYGEN BREATHING; PERINATAL PERIOD; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; RAT; ROOM TEMPERATURE; TREATMENT FAILURE;

ADMINISTRATION, INTRANASAL; ANIMALS; ANIMALS, NEWBORN; DISEASE MODELS, ANIMAL; HUMANS; HYPOTHERMIA, INDUCED; HYPOXIA-ISCHEMIA, BRAIN; INSULIN-LIKE GROWTH FACTOR I; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

RATTUS;

EID: 79953178199     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.02.013     Document Type: Article

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