Pro-bone and antifat effects of green tea and its polyphenol, epigallocatechin, in rat mesenchymal stem cells in vitro

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 18, 2011, Pages 9870-9876

  Ko, Chun Hay ^a   Siu, Wing Sum ^a   Wong, Hing Lok ^a   Shum, Wai Ting ^a   Fung, Kwok Pui ^a   Lau, Clara Bik San ^a   Leung, Ping Chung ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

adipogenesis; bone metabolism; epigallocatechin; green tea; mesenchymal stem cell; osteogenesis

Indexed keywords

ADIPOGENESIS; BONE METABOLISM; EPIGALLOCATECHIN; GREEN TEA; MESENCHYMAL STEM CELL; OSTEOGENESIS;

CALCIUM; CELL CULTURE; FATTY ACIDS; FLOWCHARTING; MOLECULAR WEIGHT; PHENOLS; PHOSPHATASES; RATS; STEM CELLS; TRANSCRIPTION FACTORS;

BONE;

CATECHIN; DRUG DERIVATIVE; GALLOCATECHIN; PLANT EXTRACT; POLYPHENOL;

ADIPOGENESIS; ANIMAL; ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CHEMISTRY; DRUG EFFECT; MALE; MESENCHYMAL STEM CELL; RAT; SPRAGUE DAWLEY RAT; TEA;

ADIPOGENESIS; ANIMALS; CAMELLIA SINENSIS; CATECHIN; CELL DIFFERENTIATION; MALE; MESENCHYMAL STEM CELLS; OSTEOGENESIS; PLANT EXTRACTS; POLYPHENOLS; RATS; RATS, SPRAGUE-DAWLEY; TEA;

RATTUS;

EID: 80053103834     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf202015t     Document Type: Article

References (41)

1. Cabrera, C.; Artacho, R.; Gimenez, R. Beneficial effects of green tea-A review J. Am. Coll. Nutr. 2006, 25 (2) 79-99 (Pubitemid 46939847)
2. Xu, J. Z.; Yeung, S. Y.; Chang, Q.; Huang, Y.; Chen, Z. Y. Comparison of antioxidant activity and bioavailability of tea epicatechins with their epimers Br. J. Nutr. 2004, 91 (6) 873-881 (Pubitemid 38931451)
3. Khokhar, S.; Venema, D.; Hollman, P. C.; Dekker, M.; Jongen, W. A RP-HPLC method for the determination of tea catechins Cancer Lett. 1997, 114 (1-2) 171-172 (Pubitemid 27140103)
4. Cooper, R.; Morre, D. J.; Morre, D. M. Medicinal benefits of green tea: Part II. review of anticancer properties J. Altern. Complementary Med. 2005, 11 (4) 639-652 (Pubitemid 41279080)
5. Wolfram, S. Effects of green tea and EGCG on cardiovascular and metabolic health J. Am. Coll. Nutr. 2007, 26 (4) 373S-388S (Pubitemid 47579907)
6. Weinreb, O.; Mandel, S.; Amit, T.; Youdim, M. B. Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases J. Nutr. Biochem 2004, 15 (9) 506-516 (Pubitemid 39209392)
7. Devine, A.; Hodgson, J. M.; Dick, I. M.; Prince, R. L. Tea drinking is associated with benefits on bone density in older women Am. J. Clin. Nutr. 2007, 86 (4) 1243-1247 (Pubitemid 47538334)
8. Hegarty, V. M.; May, H. M.; Khaw, K. T. Tea drinking and bone mineral density in older women Am. J. Clin. Nutr. 2000, 71 (4) 1003-1007 (Pubitemid 30176586)
9. Ko, C. H.; Lau, K. M.; Choy, W. Y.; Leung, P. C. Effects of tea catechins, epigallocatechin, gallocatechin, and gallocatechin gallate, on bone metabolism J. Agric. Food Chem. 2009, 57 (16) 7293-7397
10. Vali, B.; Rao, L. G.; El-Sohemy, A. Epigallocatechin-3-gallate increases the formation of mineralized bone nodules by human osteoblast-like cells J. Nutr. Biochem. 2007, 18 (5) 341-347 (Pubitemid 46613954)
11. Yun, J. H.; Kim, C. S.; Cho, K. S.; Chai, J. K.; Kim, C. K.; Choi, S. H. (-)-Epigallocatechin gallate induces apoptosis, via caspase activation, in osteoclasts differentiated from RAW 264.7 cells J. Periodontal Res. 2007, 42 (3) 212-218
12. Bäckesjö, C. M.; Li, Y.; Lindgren, U.; Haldosén, L. A. Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells J. Bone Miner. Res. 2006, 21 (7) 993-1002
13. Duque, G. Bone and fat connection in aging bone Curr. Opin. Rheumatol. 2008, 20 (4) 429-434
14. Nuttall, M. E.; Gimble, J. M. Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications Curr. Opin. Pharmacol. 2004, 4 (3) 290-294 (Pubitemid 38585315)
15. Furuyashiki, T.; Nagayasu, H.; Aoki, Y.; Bessho, H.; Hashimoto, T.; Kanazawa, K.; Ashida, H. Tea catechin suppresses adipocyte differentiation accompanied by down-regulation of PPARgamma2 and C/EBPalpha in 3T3-L1 cells Biosci., Biotechnol., Biochem. 2004, 68 (11) 2353-2359 (Pubitemid 40033512)
16. Ko, C. H.; Siu, W. S.; Lau, C. P.; Lau, C. B.; Fung, K. P.; Leung, P. C. Osteoprotective effects of Fructus Ligustri Lucidi aqueous extract in aged ovariectomized rats Chin. Med. 2010, 5, 39
17. Heim, M.; Frank, O.; Kampmann, G.; Sochocky, N.; Pennimpede, T.; Fuchs, P.; Hunziker, W.; Weber, P.; Martin, I.; Bendik, I. The phytoestrogen genistein enhances osteogenesis and represses adipogenic differentiation of human primary bone marrow stromal cells Endocrinology 2004, 145 (2) 848-859 (Pubitemid 38183829)
18. Neubauer, M.; Fischbach, C.; Bauer-Kreisel, P.; Lieb, E.; Hacker, M.; Tessmar, J.; Schulz, M. B.; Goepferich, A.; Blunk, T. Basic fibroblast growth factor enhances PPARgamma ligand-induced adipogenesis of mesenchymal stem cells FEBS Lett. 2004, 577 (1-2) 277-283 (Pubitemid 39452398)
19. Gimble, J. M.; Zvonic, S.; Floyd, Z. E.; Kassem, M.; Nuttall, M. E. Playing with bone and fat J. Cell Biochem. 2006, 98 (2) 251-266
20. Nishikawa, K.; Nakashima, T.; Takeda, S.; Isogai, M.; Hamada, M.; Kimura, A.; Kodama, T.; Yamaguchi, A.; Owen, M. J.; Takahashi, S.; Takayanagi, H. Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation J. Clin. Invest. 2010, 120 (10) 3455-3465
21. Rosen, C. J.; Bouxsein, M. L. Mechanisms of disease: is osteoporosis the obesity of bone? Nat. Clin. Pract. Rheumatol. 2006, 2 (1) 35-43 (Pubitemid 43153647)
22. Siffert, R. S. The role of alkaline phosphatase in osteogenesis J. Exp. Med. 1951, 93 (5) 415-426
23. Banerjee, C.; Javed, A.; Choi, J. Y.; Green, J.; Rosen, V.; van Wijnen, A. J.; Stein, J. L.; Lian, J. B.; Stein, G. S. Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype Endocrinology 2001, 142 (9) 4026-4039 (Pubitemid 32802676)
24. Lee, H. S.; Kim, M. K.; Kim, Y. K.; Jung, E. Y.; Park, C. S.; Woo, M. J.; Lee, S. H.; Kim, J. S.; Suh, H. J. Stimulation of osteoblastic differentiation and mineralization in MC3T3-E1 cells by antler and fermented antler using Cordyceps militaris J. Ethnopharmacol. 2011, 133 (2) 710-717
25. Butler, W. T. The nature and significance of osteopontin Connect. Tissue Res. 1989, 23 (2-3) 123-136
26. Shin, D. W.; Kim, S. N.; Lee, S. M.; Lee, W.; Song, M. J.; Park, S. M.; Lee, T. R.; Baik, J. H.; Kim, H. K.; Hong, J. H.; Noh, M. (-)-Catechin promotes adipocyte differentiation in human bone marrow mesenchymal stem cells through PPAR gamma transactivation Biochem. Pharmacol. 2009, 77 (1) 125-133
27. Chen, C. H.; Ho, M. L.; Chang, J. K.; Hung, S. H.; Wang, G. Green tea catechin enhances osteogenesis in a bone marrow mesenchymal stem cell line J. Osteoporosis Int. 2005, 16 (12) 2039-2045 (Pubitemid 41790925)
28. Li, J. Z.; Li, H.; Dunford, B.; Holman, D.; Beres, B.; Pittman, D. D.; Hankins, G. R.; Helm, G. A. Rat strain differences in the ectopic osteogenic potential of recombinant human BMP adenoviruses Mol. Ther. 2003, 8 (5) 822-829 (Pubitemid 37527458)
29. Peister, A.; Mellad, J. A.; Larson, B. L.; Hall, B. M.; Gibson, L. F.; Prockop, D. J. Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential Blood 2004, 103 (5) 1662-1668 (Pubitemid 38268957)
30. Jones, J. R.; Barrick, C.; Kim, K. A.; Lindner, J.; Blondeau, B.; Fujimoto, Y.; Shiota, M.; Kesterson, R. A.; Kahn, B. B.; Magnuson, M. A. Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance Proc. Natl. Acad. Sci. U.S.A. 2005, 102 (17) 6207-6212 (Pubitemid 40594279)
31. Millward, C. A.; Heaney, J. D.; Sinasac, D. S.; Chu, E. C.; Bederman, I. R.; Gilge, D. A.; Previs, S. F.; Croniger, C. M. Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta are protected against diet-induced obesity Diabetes 2007, 56 (1) 161-167
32. Farmer, S. R. Regulation of PPARgamma activity during adipogenesis Int. J. Obes. (London) 2005, 29 (Suppl. 1) S13-S16
33. Bernlohr, D. A.; Simpson, M. A.; Hertzel, A. V.; Banaszak, L. J. Intracellular lipid-binding proteins and their genes Annu. Rev. Nutr. 1997, 17, 277-303 (Pubitemid 27328802)
34. Reese-Wagoner, A.; Thompson, J.; Banaszak, L. Structural properties of the adipocyte lipid binding protein Biochim. Biophys. Acta 1999, 1441 (2-3) 106-116 (Pubitemid 29537731)
35. Junqueira, V. B.; Barros, S. B.; Chan, S. S.; Rodrigues, L.; Giavarotti, L.; Abud, R. L.; Deucher, G. P. Aging and oxidative stress Mol. Aspects Med. 2004, 25 (1-2) 5-16 (Pubitemid 38401927)
36. Manolagas, S. C. From estrogen-centric to aging and oxidative stress: A revised perspective of the pathogenesis of osteoporosis Endocr. Rev. 2010, 31 (3) 266-300
37. Shen, C. L.; Wang, P.; Guerrieri, J.; Yeh, J. K.; Wang, J. S. Protective effect of green tea polyphenols on bone loss in middle-aged female rats Osteoporosis Int. 2008, 19 (7) 979-990
38. Shen, C. L.; Yeh, J. K.; Cao, J. J.; Tatum, O. L.; Dagda, R. Y.; Wang, J. S. Green tea polyphenols mitigate bone loss of female rats in a chronic inflammation-induced bone loss model J. Nutr. Biochem. 2010, 21 (10) 968-974
39. Shen, C. L.; Yeh, J. K.; Cao, J. J.; Chyu, M. C.; Wang, J. S. Green tea and bone health: Evidence from laboratory studies Pharmacol. Res. 2011, 64 (2) 155-161
40. Kasper, G.; Mao, L.; Geissler, S.; Draycheva, A.; Trippens, J.; Kühnisch, J.; Tschirschmann, M.; Kaspar, K.; Perka, C.; Duda, G. N.; Klose, J. Insights into mesenchymal stem cell aging: involvement of antioxidant defense and actin cytoskeleton Stem Cells 2009, 27 (6) 1288-1297
41. Lee, M. J.; Maliakal, P.; Chen, L.; Meng, X.; Bondoc, F. Y.; Prabhu, S.; Lambert, G.; Mohr, S.; Yang, C. S. Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: Formation of different metabolites and individual variability Cancer Epidemiol. Biomarkers Prev. 2002, 11 (10 Part 1) 1025-1032 (Pubitemid 35192653)