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Volumn 194, Issue , 2011, Pages 241-249

Differential effect of amyloid beta on the cytochrome P450 epoxygenase activity in rat brain

Author keywords

Alzheimer's disease; Amyloid beta; Epoxyeicosatrienoic acids; Epoxygenase

Indexed keywords

11,12 EPOXY 5,8,14 ICOSATRIENOIC ACID; 14,15 EPOXY 5,8,11 ICOSATRIENOIC ACID; AMYLOID BETA PROTEIN; CYTOCHROME P450; CYTOCHROME P450 EPOXYGENASE; EPOXYICOSATRIENOIC ACID; HYDROXYICOSATETRAENOIC ACID; UNCLASSIFIED DRUG;

EID: 80053098381     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.07.058     Document Type: Article
Times cited : (33)

References (65)
  • 1
    • 79954994732 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids enhance axonal growth in primary sensory and cortical neuronal cell cultures
    • Abdu E., Bruun D.A., Yang D., Yang J., Inceoglu B., Hammock B.D., Alkayed N.J., Lein P.J. Epoxyeicosatrienoic acids enhance axonal growth in primary sensory and cortical neuronal cell cultures. J Neurochem 2011, 117:632-642.
    • (2011) J Neurochem , vol.117 , pp. 632-642
    • Abdu, E.1    Bruun, D.A.2    Yang, D.3    Yang, J.4    Inceoglu, B.5    Hammock, B.D.6    Alkayed, N.J.7    Lein, P.J.8
  • 2
    • 33750807720 scopus 로고    scopus 로고
    • Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow
    • Alkayed N.J., Birks E.K., Hudetz A.G., Roman R.J., Henderson L., Harder D.R. Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow. Am J Physiol 1996, 271:H1541-H1546.
    • (1996) Am J Physiol , vol.271
    • Alkayed, N.J.1    Birks, E.K.2    Hudetz, A.G.3    Roman, R.J.4    Henderson, L.5    Harder, D.R.6
  • 3
    • 0030965729 scopus 로고    scopus 로고
    • Role of P-450 arachidonic acid epoxygenase in the response of cerebral blood flow to glutamate in rats
    • Alkayed N.J., Birks E.K., Narayanan J., Petrie K.A., Kohler-Cabot A.E., Harder D.R. Role of P-450 arachidonic acid epoxygenase in the response of cerebral blood flow to glutamate in rats. Stroke 1997, 28:1066-1072.
    • (1997) Stroke , vol.28 , pp. 1066-1072
    • Alkayed, N.J.1    Birks, E.K.2    Narayanan, J.3    Petrie, K.A.4    Kohler-Cabot, A.E.5    Harder, D.R.6
  • 4
    • 0029930387 scopus 로고    scopus 로고
    • Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes
    • Alkayed N.J., Narayanan J., Gebremedhin D., Medhora M., Roman R.J., Harder D.R. Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes. Stroke 1996, 27:971-979.
    • (1996) Stroke , vol.27 , pp. 971-979
    • Alkayed, N.J.1    Narayanan, J.2    Gebremedhin, D.3    Medhora, M.4    Roman, R.J.5    Harder, D.R.6
  • 5
    • 0026584785 scopus 로고
    • Brain synthesis and cerebrovascular action of epoxygenase metabolites of arachidonic acid
    • Amruthesh S.C., Falck J.R., Ellis E.F. Brain synthesis and cerebrovascular action of epoxygenase metabolites of arachidonic acid. J Neurochem 1992, 58:503-510.
    • (1992) J Neurochem , vol.58 , pp. 503-510
    • Amruthesh, S.C.1    Falck, J.R.2    Ellis, E.F.3
  • 6
    • 0026566180 scopus 로고
    • Cerebellar atrophy as a CT marker for mixed dementia
    • Barclay L.L., Brady P.A. Cerebellar atrophy as a CT marker for mixed dementia. Biol Psychiatry 1992, 31:520-524.
    • (1992) Biol Psychiatry , vol.31 , pp. 520-524
    • Barclay, L.L.1    Brady, P.A.2
  • 7
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid beta protein toxicity
    • Behl C., Davis J.B., Lesley R., Schubert D. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 1994, 77:817-827.
    • (1994) Cell , vol.77 , pp. 817-827
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 8
    • 0025863618 scopus 로고
    • Neuropathological staging of Alzheimer-related changes
    • Braak H., Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol 1991, 82:239-259.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 9
    • 0031596284 scopus 로고    scopus 로고
    • Evolution of neuronal changes in the course of Alzheimer's disease
    • Braak H., Braak E. Evolution of neuronal changes in the course of Alzheimer's disease. J Neural Transm Suppl 1998, 53:127-140.
    • (1998) J Neural Transm Suppl , vol.53 , pp. 127-140
    • Braak, H.1    Braak, E.2
  • 10
    • 0029866991 scopus 로고    scopus 로고
    • Beta-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger
    • Bruce A.J., Malfroy B., Baudry M. beta-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger. Proc Natl Acad Sci U S A 1996, 93:2312-2316.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 2312-2316
    • Bruce, A.J.1    Malfroy, B.2    Baudry, M.3
  • 11
    • 0036384287 scopus 로고    scopus 로고
    • Identification of a novel cytochrome P450, CYP4X1, with unique localization specific to the brain
    • Bylund J., Zhang C., Harder D.R. Identification of a novel cytochrome P450, CYP4X1, with unique localization specific to the brain. Biochem Biophys Res Commun 2002, 296:677-684.
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 677-684
    • Bylund, J.1    Zhang, C.2    Harder, D.R.3
  • 13
    • 0035725998 scopus 로고    scopus 로고
    • Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis
    • Chen J.K., Capdevila J., Harris R.C. Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis. Mol Cell Biol 2001, 21:6322-6331.
    • (2001) Mol Cell Biol , vol.21 , pp. 6322-6331
    • Chen, J.K.1    Capdevila, J.2    Harris, R.C.3
  • 14
    • 0037200117 scopus 로고    scopus 로고
    • Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability
    • Dahlgren K.N., Manelli A.M., Stine W.B., Baker L.K., Krafft G.A., LaDu M.J. Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability. J Biol Chem 2002, 277:32046-32053.
    • (2002) J Biol Chem , vol.277 , pp. 32046-32053
    • Dahlgren, K.N.1    Manelli, A.M.2    Stine, W.B.3    Baker, L.K.4    Krafft, G.A.5    LaDu, M.J.6
  • 16
  • 17
    • 57349115247 scopus 로고    scopus 로고
    • Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats
    • Dunn K.M., Renic M., Flasch A.K., Harder D.R., Falck J., Roman R.J. Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 2008, 295:H2455-H2465.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Dunn, K.M.1    Renic, M.2    Flasch, A.K.3    Harder, D.R.4    Falck, J.5    Roman, R.J.6
  • 19
    • 0031714732 scopus 로고    scopus 로고
    • The relationships between age, sex, and the incidence of Dementia and Alzheimer disease: a meta-analysis
    • Gao S., Hendrie H.C., Hall K.S., Hui S. The relationships between age, sex, and the incidence of Dementia and Alzheimer disease: a meta-analysis. Arch Gen Psychiatry 1998, 55:809-815.
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 809-815
    • Gao, S.1    Hendrie, H.C.2    Hall, K.S.3    Hui, S.4
  • 20
  • 26
    • 0024331440 scopus 로고
    • Endogenous epoxyeicosatrienoic acids. Cytochrome P-450 controlled stereoselectivity of the hepatic arachidonic acid epoxygenase
    • Karara A., Dishman E., Blair I., Falck J.R., Capdevila J.H. Endogenous epoxyeicosatrienoic acids. Cytochrome P-450 controlled stereoselectivity of the hepatic arachidonic acid epoxygenase. J Biol Chem 1989, 264:19822-19827.
    • (1989) J Biol Chem , vol.264 , pp. 19822-19827
    • Karara, A.1    Dishman, E.2    Blair, I.3    Falck, J.R.4    Capdevila, J.H.5
  • 28
    • 0036458808 scopus 로고    scopus 로고
    • ERK activation and nuclear translocation in amyloid-beta peptide- and iron-stressed neuronal cell cultures
    • Kuperstein F., Yavin E. ERK activation and nuclear translocation in amyloid-beta peptide- and iron-stressed neuronal cell cultures. Eur J Neurosci 2002, 16:44-54.
    • (2002) Eur J Neurosci , vol.16 , pp. 44-54
    • Kuperstein, F.1    Yavin, E.2
  • 29
    • 0028281506 scopus 로고
    • Amyloid plaques in cerebellar cortex and the integrity of Purkinje cell dendrites
    • Li Y.T., Woodruff-Pak D.S., Trojanowski J.Q. Amyloid plaques in cerebellar cortex and the integrity of Purkinje cell dendrites. Neurobiol Aging 1994, 15:1-9.
    • (1994) Neurobiol Aging , vol.15 , pp. 1-9
    • Li, Y.T.1    Woodruff-Pak, D.S.2    Trojanowski, J.Q.3
  • 30
    • 23044439770 scopus 로고    scopus 로고
    • Hypoxic preconditioning and tolerance via hypoxia inducible factor (HIF) 1alpha-linked induction of P450 2C11 epoxygenase in astrocytes
    • Liu M., Alkayed N.J. Hypoxic preconditioning and tolerance via hypoxia inducible factor (HIF) 1alpha-linked induction of P450 2C11 epoxygenase in astrocytes. J Cereb Blood Flow Metab 2005, 25:939-948.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 939-948
    • Liu, M.1    Alkayed, N.J.2
  • 31
    • 33645999663 scopus 로고    scopus 로고
    • Expression of microsomal epoxide hydrolase is elevated in Alzheimer's hippocampus and induced by exogenous beta-amyloid and trimethyl-tin
    • Liu M., Sun A., Shin E.J., Liu X., Kim S.G., Runyons C.R., Markesbery W., Kim H.C., Bing G. Expression of microsomal epoxide hydrolase is elevated in Alzheimer's hippocampus and induced by exogenous beta-amyloid and trimethyl-tin. Eur J Neurosci 2006, 23:2027-2034.
    • (2006) Eur J Neurosci , vol.23 , pp. 2027-2034
    • Liu, M.1    Sun, A.2    Shin, E.J.3    Liu, X.4    Kim, S.G.5    Runyons, C.R.6    Markesbery, W.7    Kim, H.C.8    Bing, G.9
  • 33
    • 28044446528 scopus 로고    scopus 로고
    • Intraneuronal beta-amyloid expression downregulates the Akt survival pathway and blunts the stress response
    • Magrane J., Rosen K.M., Smith R.C., Walsh K., Gouras G.K., Querfurth H.W. Intraneuronal beta-amyloid expression downregulates the Akt survival pathway and blunts the stress response. J Neurosci 2005, 25:10960-10969.
    • (2005) J Neurosci , vol.25 , pp. 10960-10969
    • Magrane, J.1    Rosen, K.M.2    Smith, R.C.3    Walsh, K.4    Gouras, G.K.5    Querfurth, H.W.6
  • 34
    • 0032902974 scopus 로고    scopus 로고
    • Oxidative alterations in Alzheimer's disease
    • Markesbery W.R., Carney J.M. Oxidative alterations in Alzheimer's disease. Brain Pathol 1999, 9:133-146.
    • (1999) Brain Pathol , vol.9 , pp. 133-146
    • Markesbery, W.R.1    Carney, J.M.2
  • 37
    • 30544449595 scopus 로고    scopus 로고
    • Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis
    • Michaelis U.R., Fisslthaler B., Barbosa-Sicard E., Falck J.R., Fleming I., Busse R. Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis. J Cell Sci 2005, 118:5489-5498.
    • (2005) J Cell Sci , vol.118 , pp. 5489-5498
    • Michaelis, U.R.1    Fisslthaler, B.2    Barbosa-Sicard, E.3    Falck, J.R.4    Fleming, I.5    Busse, R.6
  • 38
    • 0028491608 scopus 로고
    • The molecular genetics of Alzheimer's disease
    • Mullan M., Crawford F. The molecular genetics of Alzheimer's disease. Mol Neurobiol 1994, 9:15-22.
    • (1994) Mol Neurobiol , vol.9 , pp. 15-22
    • Mullan, M.1    Crawford, F.2
  • 39
    • 0034109792 scopus 로고    scopus 로고
    • Cerebral microvascular endothelial cell tube formation: role of astrocytic epoxyeicosatrienoic acid release
    • Munzenmaier D.H., Harder D.R. Cerebral microvascular endothelial cell tube formation: role of astrocytic epoxyeicosatrienoic acid release. Am J Physiol Heart Circ Physiol 2000, 278:H1163-H1167.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Munzenmaier, D.H.1    Harder, D.R.2
  • 42
    • 80055108025 scopus 로고    scopus 로고
    • Primary culture of hippocampal neurons from P0 newborn rats
    • pii: 895
    • Nunez J. Primary culture of hippocampal neurons from P0 newborn rats. J Vis Exp 2008, (19). pii: 895.
    • (2008) J Vis Exp , Issue.19
    • Nunez, J.1
  • 43
    • 0029860523 scopus 로고    scopus 로고
    • Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons
    • Paradis E., Douillard H., Koutroumanis M., Goodyer C., LeBlanc A. Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons. J Neurosci 1996, 16:7533-7539.
    • (1996) J Neurosci , vol.16 , pp. 7533-7539
    • Paradis, E.1    Douillard, H.2    Koutroumanis, M.3    Goodyer, C.4    LeBlanc, A.5
  • 44
    • 1542316987 scopus 로고    scopus 로고
    • Abeta-induced vascular oxidative stress and attenuation of functional hyperemia in mouse somatosensory cortex
    • Park L., Anrather J., Forster C., Kazama K., Carlson G.A., Iadecola C. Abeta-induced vascular oxidative stress and attenuation of functional hyperemia in mouse somatosensory cortex. J Cereb Blood Flow Metab 2004, 24:334-342.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 334-342
    • Park, L.1    Anrather, J.2    Forster, C.3    Kazama, K.4    Carlson, G.A.5    Iadecola, C.6
  • 47
    • 0027447286 scopus 로고
    • Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state
    • Pike C.J., Burdick D., Walencewicz A.J., Glabe C.G., Cotman C.W. Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state. J Neurosci 1993, 13:1676-1687.
    • (1993) J Neurosci , vol.13 , pp. 1676-1687
    • Pike, C.J.1    Burdick, D.2    Walencewicz, A.J.3    Glabe, C.G.4    Cotman, C.W.5
  • 49
    • 0036947327 scopus 로고    scopus 로고
    • Stage-dependent and sector-specific neuronal loss in hippocampus during Alzheimer's disease
    • Rössler M., Zarski R., Bohl J., Ohm T.G. Stage-dependent and sector-specific neuronal loss in hippocampus during Alzheimer's disease. Acta Neuropathol 2002, 103:363-369.
    • (2002) Acta Neuropathol , vol.103 , pp. 363-369
    • Rössler, M.1    Zarski, R.2    Bohl, J.3    Ohm, T.G.4
  • 51
    • 0001181116 scopus 로고    scopus 로고
    • Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics
    • Selkoe D.J., Schenk D. Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics. Annu Rev Pharmacol Toxicol 2003, 43:545-584.
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 545-584
    • Selkoe, D.J.1    Schenk, D.2
  • 52
    • 70350365853 scopus 로고    scopus 로고
    • NADPH oxidase mediates beta-amyloid peptide-induced activation of ERK in hippocampal organotypic cultures
    • Serrano F., Chang A., Hernandez C., Pautler R.G., Sweatt J.D., Klann E. NADPH oxidase mediates beta-amyloid peptide-induced activation of ERK in hippocampal organotypic cultures. Mol Brain 2009, 5:2-31.
    • (2009) Mol Brain , vol.5 , pp. 2-31
    • Serrano, F.1    Chang, A.2    Hernandez, C.3    Pautler, R.G.4    Sweatt, J.D.5    Klann, E.6
  • 55
    • 77749264948 scopus 로고    scopus 로고
    • Regulation of stargazin synaptic trafficking by C-terminal PDZ ligand phosphorylation in bidirectional synaptic plasticity
    • Stein E.L., Chetkovich D.M. Regulation of stargazin synaptic trafficking by C-terminal PDZ ligand phosphorylation in bidirectional synaptic plasticity. J Neurochem 2010, 113:42-53.
    • (2010) J Neurochem , vol.113 , pp. 42-53
    • Stein, E.L.1    Chetkovich, D.M.2
  • 56
    • 0038176528 scopus 로고    scopus 로고
    • In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis
    • Stine W.B., Dahlgren K.N., Krafft G.A., LaDu M.J. In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis. J Biol Chem 2003, 278:11612-11622.
    • (2003) J Biol Chem , vol.278 , pp. 11612-11622
    • Stine, W.B.1    Dahlgren, K.N.2    Krafft, G.A.3    LaDu, M.J.4
  • 57
    • 34447636593 scopus 로고    scopus 로고
    • 3D maps from multiple MRI illustrate changing atrophy patterns as subjects progress from mild cognitive impairment to Alzheimer's disease
    • Whitwell J.L., Przybelski S.A., Weigand S.D., Knopman D.S., Boeve B.F., Petersen R.C., Jack C.R. 3D maps from multiple MRI illustrate changing atrophy patterns as subjects progress from mild cognitive impairment to Alzheimer's disease. Brain 2007, 130:1777-1786.
    • (2007) Brain , vol.130 , pp. 1777-1786
    • Whitwell, J.L.1    Przybelski, S.A.2    Weigand, S.D.3    Knopman, D.S.4    Boeve, B.F.5    Petersen, R.C.6    Jack, C.R.7
  • 59
    • 0036685522 scopus 로고    scopus 로고
    • Inflammation in neurodegenerative disease-a double-edged sword
    • Wyss-Coray T., Mucke L. Inflammation in neurodegenerative disease-a double-edged sword. Neuron 2002, 35:419-432.
    • (2002) Neuron , vol.35 , pp. 419-432
    • Wyss-Coray, T.1    Mucke, L.2
  • 60
    • 70349952431 scopus 로고    scopus 로고
    • Oligomeric aggregates of amyloid beta peptide 1-42 activate ERK/MAPK in SH-SY5Y cells via the alpha7 nicotinic receptor
    • Young K.F., Pasternak S.H., Rylett R.J. Oligomeric aggregates of amyloid beta peptide 1-42 activate ERK/MAPK in SH-SY5Y cells via the alpha7 nicotinic receptor. Neurochem Int 2009, 55:796-801.
    • (2009) Neurochem Int , vol.55 , pp. 796-801
    • Young, K.F.1    Pasternak, S.H.2    Rylett, R.J.3
  • 61
    • 48749116836 scopus 로고    scopus 로고
    • Antiangiogenic effect of inhibitors of cytochrome P450 on rats with glioblastoma multiforme
    • Zagorac D., Jakovcevic D., Gebremedhin D., Harder D.R. Antiangiogenic effect of inhibitors of cytochrome P450 on rats with glioblastoma multiforme. J Cereb Blood Flow Metab 2008, 28:1431-1439.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 1431-1439
    • Zagorac, D.1    Jakovcevic, D.2    Gebremedhin, D.3    Harder, D.R.4
  • 62
    • 0035965327 scopus 로고    scopus 로고
    • Epoxygenase pathways of arachidonic acid metabolism
    • Zeldin D.C. Epoxygenase pathways of arachidonic acid metabolism. J Biol Chem 2001, 276:36059-36062.
    • (2001) J Biol Chem , vol.276 , pp. 36059-36062
    • Zeldin, D.C.1
  • 63
    • 0036901546 scopus 로고    scopus 로고
    • Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic acid
    • Zhang C., Harder D.R. Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic acid. Stroke 2002, 33:2957-2964.
    • (2002) Stroke , vol.33 , pp. 2957-2964
    • Zhang, C.1    Harder, D.R.2
  • 65
    • 78649446918 scopus 로고    scopus 로고
    • Gene delivery of cytochrome p450 epoxygenase ameliorates monocrotaline-induced pulmonary artery hypertension in rats
    • Zheng C., Wang L., Li R., Ma B., Tu L., Xu X., Dackor R.T., Zeldin D.C., Wang D.W. Gene delivery of cytochrome p450 epoxygenase ameliorates monocrotaline-induced pulmonary artery hypertension in rats. Am J Respir Cell Mol Biol 2010, 43:740-749.
    • (2010) Am J Respir Cell Mol Biol , vol.43 , pp. 740-749
    • Zheng, C.1    Wang, L.2    Li, R.3    Ma, B.4    Tu, L.5    Xu, X.6    Dackor, R.T.7    Zeldin, D.C.8    Wang, D.W.9


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