The development of a practical multikilogram synthesis of the chiral β-amino acid imagabalin hydrochloride (PD-0332334) via asymmetric hydrogenation

Organic Process Research and Development

Volumn 15, Issue 5, 2011, Pages 1172-1177

  Birch, Melissa ^a   Challenger, Stephen ^a   Crochard, Jean Philippe ^a   Fradet, David ^a   Jackman, Hayley ^a   Luan, Amy ^a   Madigan, Evelyn ^a   McDowall, Neil ^a   Meldrum, Kevin ^a   Gordon, Charles M ^a   Widegren, Magnus ^a   Yeo, Stephen ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ASYMMETRIC HYDROGENATION; ENAMIDES; HIGH PURITY; HYDROCHLORIDE SALTS; PROTECTING GROUP; RECRYSTALLISATION;

AMINO ACIDS; CHROMATOGRAPHY; RHODIUM;

HYDROGENATION;

EID: 80053034163     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op2001639     Document Type: Article

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