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Volumn 47, Issue 38, 2011, Pages 10770-10772

Expedient entry to the piperazinohydroisoquinoline ring system using a sequential Ugi/Pictet-Spengler/reductive methylation reaction protocol

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ALKALOID; AMINOACETALDEHYDE DIMETHYLACETAL; ANTINEOPLASTIC ALKALOID; N DEMETHYLASE; PIPERAZINOHYDROISOQUINOLINE; QUINOLINE; UNCLASSIFIED DRUG;

EID: 80052956660     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c1cc10759c     Document Type: Article
Times cited : (30)

References (31)
  • 22
    • 84890574887 scopus 로고    scopus 로고
    • ed. J. Zhu and H. Bienaymé, Wiley-VCH, Weinheim, Germany, ch. 2, 33-75 For a review of construction of related piperazine scaffolds using a multicomponent reaction see
    • S. Marcaccini and T. Torroba, Multicomponent Reactions, ed., J. Zhu, and, H. Bienaymé, Wiley-VCH, Weinheim, Germany, 2005, ch. 2, pp. 33-75
    • (2005) Multicomponent Reactions
    • Marcaccini, S.1    Torroba, T.2
  • 23
    • 77956050442 scopus 로고    scopus 로고
    • For related Ugi/Pictet-Spengler combinations see
    • A. Domling Y. Huang Synthesis 2010 2859
    • (2010) Synthesis , pp. 2859
    • Domling, A.1    Huang, Y.2
  • 31
    • 33947339438 scopus 로고
    • Microwave reactions were conducted using a CEM Discover Synthesis™ Unit(CEM Corp., Matthews, NC). For the synthesis of this compound see the ESI The absolute stereochemistry of this compound was suggested as [1(R)-4(R)-6(S) on the basis of the use of optically pure (-)-(S)-N-Boc-3-(3,4-dimethoxyphenyl) alanine 10 as starting material in the Ugi reaction
    • H. T. Clarke H. B. Gillespie S. Z. Weisshaus J. Am. Chem. Soc. 1933 55 4571
    • (1933) J. Am. Chem. Soc. , vol.55 , pp. 4571
    • Clarke, H.T.1    Gillespie, H.B.2    Weisshaus, S.Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.