Regioselectivity of Pictet-Spengler cyclization reactions to construct the pentacyclic frameworks of the ecteinascidin-saframycin class of tetrahydroisoquinoline antitumor antibiotics

Tetrahedron Letters

Volumn 48, Issue 21, 2007, Pages 3719-3722

  Vincent, Guillaume ^a,b   Lane, Jonathan W ^a,b   Williams, Robert M ^a,b  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; BENZYLAMINE; HYDROXYL GROUP; PHENOL DERIVATIVE; SAFRAMYCIN; TETRAHYDROISOQUINOLINE; TRABECTEDIN;

ARTICLE; CYCLIZATION; EPIMERIZATION; NUCLEAR OVERHAUSER EFFECT; PICTET SPENGLER CYCLIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; REDUCTION; RING OPENING; STEREOCHEMISTRY; STEREOISOMERISM; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION;

EID: 34247205246     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.03.113     Document Type: Article

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