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Volumn 46, Issue 9, 2011, Pages 3551-3563

Design, synthesis and anti-tubercular evaluation of new 2-acylated and 2-alkylated amino-5-(4-(benzyloxy)phenyl)thiophene-3-carboxylic acid derivatives. Part 1

(4) Lu, Xiaoyun a,b Wan, Baojie c Franzblau, Scott G c You, Qidong a

a CHINA PHARMACEUTICAL UNIVERSITY (China)

b INSTITUTE OF GEOLOGY AND GEOPHYSICS (China)

c UNIVERSITY OF ILLINOIS AT CHICAGO (United States)

Author keywords

2 acylated and 2 alkylated amino 5 (4 (benzyloxy)phenyl)thiophene 3 carboxylic acid derivatives; Anti tubercular activity; MDR TB; XDR TB

Indexed keywords

2 [(5 (4 (2,6 DICHLOROBENZYLOXY)PHENYL) 3 (ETHOXYCARBONYL)THIOPHEN 2 YLAMINO)] 2 OXOACETIC ACID; 2 [(BUTYLAMINO) 5 (4 (2,6 DICHLOROBENZYLOXY)PHENYL)]THIOPHENE 3 CARBOXYLIC ACID; 2 [(CARBOXYMETHYLAMINO) 5 (4 (2,6 DICHLOROBENZYLOXY)PHENYL)]THIOPHENE 3 CARBOXYLIC ACID; 2 ACYLATED AMINO 5 (4 (BENZYLOXY)PHENYL)THIOPHENE 3 CARBOXYLIC ACID DERIVATIVE; 2 ALKYLATED AMINO 5 (4 (BENZYLOXY)PHENYL)THIOPHENE 3 CARBOXYLIC ACID DERIVATIVE; 5 [(4 (2,6 DICHLOROBENZYLOXY)PHENYL) 2 (4 CHLOROBENZAMIDO)]THIOPHENE 3 CARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; EXTENSIVELY DRUG RESISTANT TUBERCULOSIS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DOCKING; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; VERO CELL;

ANIMALS; ANTITUBERCULAR AGENTS; CARBOXYLIC ACIDS; CERCOPITHECUS AETHIOPS; DRUG DESIGN; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THIOPHENES; VERO CELLS;

EID: 80052945363 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2011.05.018 Document Type: Article

Times cited : (50)

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