Synthesis and biological evaluation of N-(aryl)-2-thiophen-2-ylacetamides series as a new class of antitubercular agents

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 24, 2007, Pages 6895-6898

  Lourenço, Maria Cristina Silva ^b   Vicente, Felipe Rodrigues ^b   Henriques, Maria das Graças Muller de Oliveira ^a   Peixoto Candéa, André Luis ^a   Borges Gonçalves, Raoni Schroeder ^a   Nogueira, Thais Cristina M ^a   de Lima Ferreira, Marcelle ^a   Nora de Souza, Marcus Vinícius ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b Funda??o Oswaldo Cruz   (Brazil)

Author keywords

Antimycobacterial activity; Thiopheneacetamides; Tuberculosis

Indexed keywords

2 THIOPHEN 2 YLACETAMIDE DERIVATIVE; ACETAMIDE DERIVATIVE; THIOPHENE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ACETAMIDES; ANIMALS; ANTITUBERCULAR AGENTS; CELL LINE; MACROPHAGES; MICE; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

MYCOBACTERIUM TUBERCULOSIS;

EID: 35948949029     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.09.096     Document Type: Article

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