Synthesis and biological evaluation of a C5-biphenyl thiolactomycin library

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 20, 2007, Pages 5643-5646

  Bhowruth, Veemal ^a   Brown, Alistair K ^a   Senior, Suzanne J ^a   Snaith, John S ^a   Besra, Gurdyal S ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Inhibitors; Mycobacterium bovis BCG; Mycobacterium tuberculosis; Mycolic acids; Thiolactomycin

Indexed keywords

5 (4 METHOXYCARBONYLBIPHENYL 4 YLMETHYL) 4 HYDROXY 3,5 DIMETHYL 5H THIOPHEN 2 ONE; BIPHENYL DERIVATIVE; THIOLACTOMYCIN; THIOPHENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; DRUG SYNTHESIS; HYDROGEN BOND; IC 50; IN VITRO STUDY; MYCOBACTERIUM BOVIS; NONHUMAN;

BIOMIMETIC MATERIALS; DATABASES, FACTUAL; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; MYCOBACTERIUM; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

MYCOBACTERIUM BOVIS BCG; MYCOBACTERIUM TUBERCULOSIS;

EID: 34548555606     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.07.082     Document Type: Article

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