Quantitative trace analysis of eight chloramphenicol isomers in urine by chiral liquid chromatography coupled to tandem mass spectrometry

Journal of Chromatography A

Volumn 1218, Issue 41, 2011, Pages 7331-7340

  Berendsen, Bjorn J A ^a   Essers, Martien L ^a   Stolker, Linda A A M ^a   Nielen, Michel W F ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Chiral separation; Chloramphenicol; Isomers and enantiomers; Mass spectrometry; Residue analysis; Urine

Indexed keywords

ANALYTES; ANALYTICAL COLUMNS; ANALYTICAL METHOD; BROAD SPECTRUM ANTIBIOTICS; CHIRAL LIQUID CHROMATOGRAPHY; CHIRAL SEPARATIONS; CHIRAL STATIONARY PHASE; CHLORAMPHENICOL; CHROMATOGRAPHIC RESOLUTIONS; CRITICAL PARAMETER; DECISION LIMIT; EU REGULATIONS; FOOD-PRODUCING ANIMALS; INTERFERING SUBSTANCES; ISOCRATIC ELUTION; LIQUID-LIQUID EXTRACTION; MATRIX; MINIMUM REQUIRED PERFORMANCE LIMITS; QUANTITATIVE METHOD; REPRODUCIBILITIES; RESIDUE ANALYSIS; SOLID-PHASE EXTRACTION; TANDEM MASS SPECTROMETRIC DETECTION; TRACE LEVEL; URINE; URINE SAMPLE;

ANIMALS; ANTIBIOTICS; BODY FLUIDS; CHIRALITY; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; ORGANIC POLYMERS; SOLVENT EXTRACTION; STEREOCHEMISTRY; TRACE ANALYSIS;

ISOMERS;

CHLORAMPHENICOL;

ANALYTICAL PARAMETERS; ARTICLE; CHIRAL CHROMATOGRAPHY; DRUG DETERMINATION; DRUG ISOLATION; DRUG LEGISLATION; DRUG URINE LEVEL; ELUTION; EUROPEAN UNION; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REFERENCE VALUE; REPRODUCIBILITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

CHLORAMPHENICOL; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; HUMANS; LEAST-SQUARES ANALYSIS; LIQUID-LIQUID EXTRACTION; METHANOL; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; STEREOISOMERISM; TANDEM MASS SPECTROMETRY;

ANIMALIA;

EID: 80052944375     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.08.046     Document Type: Article

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