SCOPUS 정보 검색 플랫폼

Volumn 46, Issue 9, 2011, Pages 3867-3876

Application of Ullmann and Ullmann-Finkelstein reactions for the synthesis of N-aryl-N-(1H-pyrazol-3-yl) acetamide or N-(1-aryl-1H-pyrazol-3-yl) acetamide derivatives and pharmacological evaluation

(5) Deprez Poulain, Rebecca a,b,c Cousaert, Nicolas a,b,c Toto, Patrick a,b,c Willand, Nicolas a,b,c Deprez, Benoit a,b,c

a UNIV LILLE (France)

b INSTITUT PASTEUR DE LILLE (France)

c PRIM (France)

Author keywords

AT1 receptor antagonists; Copper catalyzed; Patent escaping; Pyrazoles. C to N bioisosterism; Ullmann; Ullmann Finkelstein

Indexed keywords

3 (ACETYL M TOLYL AMINO) 1 (2' CYANO BIPHENYL 4 YLMETHYL) 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 (ACETYL M TOLYL AMINO) 1 [2' (1H TETRAZOL 5 YL)BIPHENYL 4 YLMETHYL] 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 (ACETYL P TOLYL AMINO) 1 (2' CYANO BIPHENYL 4 YLMETHYL) 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 (ACETYL P TOLYL AMINO) 1 [2' (1H TETRAZOL 5 YL)BIPHENYL 4 YLMETHYL] 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 (ACETYL PHENYL AMINO) 1 (2' CYANO BIPHENYL 4 YLMETHYL) 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 (ACETYL PYRIDIN 3 YL AMINO) 1 (2' CYANO BIPHENYL 4 YLMETHYL) 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 (ACETYL PYRIDIN 3 YL AMINO) 1 [2' (1H TETRAZOL 5 YL)BIPHENYL 4 YLMETHYL] 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 (ACETYLPHENYL AMINO) 1 [2' (1H TETRAZOL 5 YL)BIPHENYL 4 YLMETHYL] 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 [ACETYL (3,5 DIMETHYLPHENYL)AMINO] 1 (2' CYANO BIPHENYL 4 YLMETHYL) 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 [ACETYL (3,5 DIMETHYLPHENYL)AMINO] 1 [2' (1H TETRAZOL 5 YL)BIPHENYL 4 YLMETHYL] 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 [ACETYL (4 ETHYLPHENYL)AMINO] 1 (2' CYANO BIPHENYL 4 YLMETHYL) 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 [ACETYL (4 ETHYLPHENYL)AMINO] 1 [2' (1H TETRAZOL 5 YL)BIPHENYL 4 YLMETHYL] 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 [ACETYL (4 TERT BUTYLPHENYL)AMINO] 1 (2' CYANO BIPHENYL 4 YLMETHYL) 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 [ACETYL (4 TERT BUTYLPHENYL)AMINO] 1 [2' (1H TETRAZOL 5 YL)BIPHENYL 4 YLMETHYL] 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 [ACETYL (4 TRIFLUOROMETHYLPHENYL)AMINO] 1 (2' CYANO BIPHENYL 4 YLMETHYL) 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 ACETYLAMINO 1 (2' CYANO BIPHENYL 4 YLMETHYL) 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 ACETYLAMINO 1 (4 BROMO PHENYL) 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 ACETYLAMINO 1 (4 IODO PHENYL) 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 ACETYLAMINO 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 AMINO 1 (4 BROMO PHENYL) 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 AMINO 1 PHENYL 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 AMINO 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 3 AMINO 2 PHENYL 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 5 ACETYLAMINO 1 BUTYL 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 5 ACETYLAMINO 1 PHENYL 1H PYRAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; ACETAMIDE DERIVATIVE; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; APIXABAN; BMS 561389; LOTRAFIBAN; N (1 ARYL 1H PYRAZOL 3 YL)ACETAMIDE DERIVATIVE; N ARYL N (1H PYRAZOL 3 YL)ACETAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANALYTIC METHOD; ARTICLE; ARYLATION; DRUG DESIGN; DRUG SYNTHESIS; ULLMANN FINKELSTEIN REACTION; ULLMANN REACTION;

ACETAMIDES; ANIMALS; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PYRAZOLES; RECEPTORS, ANGIOTENSIN; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 80052936910 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2011.05.056 Document Type: Article

Times cited : (15)

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