Hymenoptera venom proteins and peptides for diagnosis and treatment of venom allergic patients

Inflammation and Allergy - Drug Targets

Volumn 10, Issue 5, 2011, Pages 420-428

  Müller, Ulrich R ^a  

^a Spital Netz Bern   (Switzerland)

Author keywords

Anaphylaxis; Apis mellifera; Apitherapy; Hymenoptera venoms; Venom immunotherapy; Vespula vulgaris

Indexed keywords

ACID PHOSPHATASE; ADRENALIN; ANTIHISTAMINIC AGENT; APAMIN; BEE VENOM; CARBOXYLESTERASE; CORTICOSTEROID; DIPEPTIDYL PEPTIDASE I; HYALURONIDASE; HYMENOPTERA VENOM; ICARAPIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G4; MAST CELL DEGRANULATING PEPTIDE; MASTOPARAN; MELITTIN; PHOSPHOLIPASE A; PHOSPHOLIPASE A2; PILOSULIN 3; PILOSULIN 4.1; PLACEBO; SECAPIN; TERTIAPIN; UNCLASSIFIED DRUG; VENOM ANTISERUM;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; DRUG EFFICACY; DRUG SAFETY; HUMAN; IMMUNOTHERAPY; INSECT ALLERGY; MULTIPLE SCLEROSIS; NONHUMAN; RHEUMATOID ARTHRITIS; TREATMENT DURATION;

EID: 80052865852     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152811797200704     Document Type: Article

References (68)

1. Sasvary, T.; Müller, U. Todesfälle an Insektenstichen in der Schweiz 1978 bis 1987. Schweiz. Med. Wschr., 1994,124,1887-1894.
2. Hoffman, D.R.; Jacobsen, R.S. Allergens in Hymenoptera venoms XII: How much protein is in a sting? Ann. Allergy, 1984, 52, 276-278.
3. Bonifazi, F.; Jutel, M.; Bilo, B.M.; Birnbaum, J.; Müller, U.; Bucher, C.; Forster, J.; Hemmer, W.; Incorvaia, C.; Mosbech, H.; Oude Elberink, J.N.; Rueff, F.; Fernandez, J.; Senna, G.E.; Jarisch, R.; Wüthrich, B. Prevention and treatment of hymenoptera venom Allergy: guidelines for clinical practice. Allergy, 2005, 60, 1459-1470.
4. Caldwell, J.R. Venoms, copper and zinc in the treatment of arthritis. Rheum. Dis. Clin. North. Amer., 1999, 25, 919-928.
5. Hoffman, D.R. Hymenoptera venoms: composition, standardization, stability. In: Monograph on Insect Allergy. Levine, M.I., Lockey, R.F,. Eds., Dave Lambert Ass: Pittsburgh, 2003, pp. 37-53.
6. King, T.P.; Guralnick, M. Hymenoptera venom allergens. In:Allergens and Allergen Immunotherapy, 4th ed. Lockey, R.F.; Ledford, D.K.; Informa healthcare: New York/London, 2008; pp. 237-250.
7. Benton, A.W.; Morse, R.A.; Stewart, J.D. Venom collection from honey bees. Science, 1963, 142, 228-229.
8. Guralnick, M.W.; Bentonm A.W. Entomological aspects of insect sting allergy. In: Monograph on insect allergy, 4th ed. Levine, M.I., Lockey, R.F., Eds. Dave Lamberts Ass.; Pittsburgh PA, 2003, pp.11-26.
9. Habermann, E. Bee and wasp venoms. Science, 1972, 177, 314-322.
10. Strong, P.N.; Wadsworth, D.F. Pharmacologically active peptides and proteins from bee venom. In: Animal Toxins. Rochat, H. Martin-Eauclaire, M.F. Birkhäuser Verlag Basel: Switzerland, 2000, pp.128-149.
11. Raghuraman, H.; Chattopadhyay, A. Melittin: a membrane-active peptide with diverse functions. Biosci. Rep., 2007, 27, 189-223.
12. Banks, B.E.; Brown, C.; Burgess, G.M. Apamin blocks certain neurotransmitter-induced increases in potassium permeability. Nature, 1979, 282, 415-417.
13. Banks, B.E. Possible therpapeutic use of a peptide from bee venom. Bull. Inst. Pasteur., 1976, 74, 137-144.
14. Kanjhan, R.; Coulson, E.J.; Adams, D.J.; Bellingham, M.C. Tertiapin-Q blocks recombinant and native large donductance K+ channels in a use dependant manner. J. Pharm. Exp. Ther., 2005, 314, 1353-1361
15. Bilo, B.M.; Ruëff, F.; Mosbech, H.; Bonifazi, F.; Oude-Elberink, J.N.G.; Birnbaum, J.; Bucher, C.; Forster, J.; Hemmer, W.; Incorvaia, C.; Kontou Fili, K.; Gawlik, R.; Müller, U.; Fernandez, J.; Jarisch, R.; Jutel, M.; Wüthrich, B. Diagnosis of Hymenoptera venom allergy. Allergy, 2005, 60, 1339-1349.
16. Dudler, T.; Schneider, T.; Annand, R.R.; Suter, M.; Blaser, K. Antigenic surface of bee venom phospholipase A2. J. Immunol., 1994, 152, 5514-5522.
17. Müller, U.; Johansen, N.; Petersen, A.; Fromberg-Nielsen, J.; Haeberli, G. Hymenoptera venom allergy: analysis of double positivity to honey bee and Vespula venom by estimation of IgE antibodies to species-specific major allergens Api m1 and Ves v5. Allergy, 2009, 64, 543-548.
18. Soldatova, L.N.; Crameri, R.; Gmachl, M.; Kemeny, D.M.; Schmidt, M.; Müller, U.R. Superior biologic activity of the recombinant bee venom allergen hyaluronidase expressed in baculovirus-infected insect cells as compared with Escherichia coli. J. Allergy. Clin. Immunol., 1998, 101, 691-698.
19. Markovic-Housley, Z.; Miglierini, G.; Soldatova, L.; Rizkallah, P.J.; Müller, U.; Schirmer, T. Crystal structure of hyaluronidase, a major allergen of bee venom. Structure, 2000, 8, 1025-1035.
20. Grunwald, T.; Bockisch, B.; Spillner, E.; Ring, J.; Bredehorst, R.; Ollert, M. Molecular cloning and expression and expression in insect cells of honey bee venom allergen acid phosphatase (Api m3). J. Allergy Clin. Immunol., 2006, 117, 848-854.
21. de Graaf, D.C.; Aerts, M.; Danneels, E.; Devreese, B. Bee, wasp and ant venomics pave the way for a component resolved diagnosis of sting allergy. J. Proteomics., 2009, 72, 145-154.
22. Blank, S.; Seisman, H.; Bockish, B.; Braren, I.; Ollert, M.W.; Grunwald, T.; Spillner, E. Identification, recombinant expression and characterization of the 100 kDa high molecular weight hymenoptera venom allergens Api m5 and Ves v3. Allergy, 2008, 63(Suppl 88), 13-14.
23. Kettner, A.; Hughes, G.J.; Frutiger, S.; Astori, M.; Roggero, M.; Spertini, F.; Corradin, G. Api m6: A new bee venom allergen. J. Allergy Clin. Immunol., 2001, 107, 914-920.
24. Winningham, K.M.; Fitch, C.D.; Schmidt, M.; Hoffman, D.R. Hymenoptera venom protease allergens. J. Allergy Clin. Immunol., 2004, 114, 928-933.
25. Peiren N, de Graaf DC, Brunain M, Bridts CH, Ebo DG, Stevens WJ, Jacobs FJ. Molecular cloning and expression of icarapin, a novel IgE-binding bee venom protein. FEBS Lett., 2006, 580, 4895-4899.
26. Piek, T. Wasp kinins and kinin analogues. In: Animal Toxins.Rochat, H., Martin-Eauclaire, M.F., Eds. Birkhäuser Verlag Basel: Switzerland, 2000; pp. 99-115.
27. Nakajiama, T.; Wakamatsu, K.; Kai, H. Mastoparan as a G protein activator. In: Animal Toxins. Rochat, H., Martin-Eauclaire, M.F., Eds. Birkhäuser Verlag Basel: Switzerland, 2000; pp.116-126.
28. Skov, L.K.; Seppälä, U.; Coen, J.F.; Crickmore, N.; King, T.P.; Kastrup, J.S.; Spangfort, M.D.; Gajhede, M. Structure of recombinant Ves v2 at 2A resolution: structural anaplysis of hyaluronidase from wasp venom. Acta. Cryst., 1996, 62, 595-604.
29. Hemmer, W.; Focke, M.; Kolarich, D.; Jarisch, R. Identification by immunoblot of venom glycoproteins displaying IgE-binding Nglycans as crossreacting allergens in honey bee and yellow-jacket venom. Clin. Exp. Allergy, 2004, 34, 460-469.
30. Hoffman, D.R.; Sakell, R.H.; Schmidt, M. Soli1, the phospholipase allergen of imported fire ant venom. J. Allergy Clin. Immunol., 2005, 115, 611-616.
31. Schmidt, M.; McConnel, T.J.; Hoffman, D.R. Production of a recombinant imported fire ant allergen, Sol i2, in native and immunoreactive form. J. Allergy Clin. Immunol., 1996, 98, 82-88.
32. Schmidt, M.; McConnell, T.J.; Hoffman, D.R. Immunological characterization of the recombinant fire ant venom allergen Sol i3. Allergy, 2003, 58, 342-349.
33. Brown, S.G.A.; Franks, R.W.; Baldo, B.A.; Heddle, R.J. Prevalence, severity, and natural history of jack jumper ant venom allergy in Tasmania. J. Allergy Clin. Immunol., 2003, 111, 187-92.
34. Davies, N.W.; Wiese, M.D.; Brown, S.G.A. Characterization of major peptides in jack jumper ant venom by mass spectrometry. Toxicon, 2004, 43, 173-183.
35. Wiese, M.D.; Brown, S.G.A.; Chataway, T.K.; Davies, N.M.; Milne, R.W.; Aulfrey, S.J.; Heddle, R.J. Myrmecia pilosula (Jack jumper ant venom: identification of allergens and revised nomenclature. Allergy, 2007, 62, 437-443.
36. Müller, U.R. Insect sting allergy. Clinical picture, diagnosis and treatment. Gustav Fischer Verlag/VCH Publishers, Stuttgart-New York, 1990.
37. Müller, U. Cardiovascular disease and anaphylaxis. Curr. Opin. Allergy Clin. Immunol., 2007, 7, 337-341.
38. Jutel, M.; Akdis, C.A. T-cell regulatory mechanisms in specific immunotherapy. Chem. Immunol. Allergy, 2008, 94, 158-171.
39. Jutel, M.; Müller, U.; Fricker, M.; Rihs, S.; Pichler, W.J.; Dahinden, C. Influence of bee venom immunotherapy on degranulation and leukotriene generation in human blood basophils. Clin. Exp. Allergy, 1996, 26, 1112-1118.
40. Hunt, K.J.; Valentine, M.D.; Sobotka, A.K.; Benton, A.W.; Amododio, F.J.; Lichtenstein, L.M. A controlled trial of immunotherapy in insect hypersensitivity. N. Engl. J. Med., 1978, 299, 157-161.
41. Müller, U.; Thurnheer, U.; Patrizzi, R.; Spiess, J.; Hoigné, R. Immunotherapy in bee sting hypersensitivity. Allergy, 1979, 34, 369-378.
42. Brown, S.G.; Wiese, M.; Blackman, K.; Heddle, R. Ant venom immunotherapy: a double blind, placebo-controlled crossover trial. Lancet, 2003, 361, 1101-1106.
43. Gillman, S.A.; Cummins, L.H.; Kozak, P.P.; Hoffman, D.R. Venom immunotherapy: comparison of rush versus conventional schedules. Ann. Allergy, 1980, 45, 351-354.
44. Müller, U.; Helbling, A.; Berchtold, E. Immunotherapy with honeybee venom and yellow jacket venom is different regarding efficacy and safety. J. Allergy Clin. Immunol., 1992, 89, 529-535.
45. Golden, D.R.; Lawrence, I.D.; Hailton, R.H.; Kagey-Sobotka, A.; Valentine, M.D.; Lichtenstein, L.M. Clinical correlation of the venom specific IgG antibody level during maintenance venom immunotherapy. J. Allergy Clin. Immunol., 1992, 90, 386-393.
46. Mosbech, H.; Malling, H.J.; Biering, I. Immunotherapy with yellow jacket venom. Allergy, 1986, 41, 95-103.
47. Müller, U.R. Bee venom allergy in beekeepers and their family members. Curr. Opin. Allergy Clin. Immunol., 2005, 5, 343-347.
48. Lessof, M.H.; Sobotka, A.K.; Lichtenstein, L.M. Effects of passive antibody in bee venom anaphylaxis. John. Hopk. Med. J., 1977, 142, 1-7.
49. Müller, U.R.; Morris, T.; Bischof, M.; Friedli, H.; Skvaril F. Combined active and passive immunotherapy in honeybee-sting allergy. J. Allergy Clin. Immunol., 1986, 78, 115-122.
50. Bousquet, J.; Fontes, A.; Aznar, R.; Robinet-Lévy, M.; Michel, F.B. Combination of active and passive immunization in honey bee venom immunotherapy. J. Allergy Clin. Immunol., 1987, 79, 947-954.
51. Müller, U.; Helbling, A.; Bischof, M. Predictive value of venomspecific IgE, IgG and IgG subclass antibodies in patients on immunotherapy with honey bee venom. Allergy, 1989, 44, 412-418.
52. Goldberg, A.; Confino-Cohen, R. Bee venom immunotherapy - how early is it effective? Allergy, 2010, 65, 391-395.
53. Lorenzetti, O.J.; Fortenberry, B.; Busby, E. Influence of bee venom in adjuvant-induced arthritic rat model. Res. Comm. Chem. Pathol. Pharmacolo., 1972, 4, 339-351.
54. Zurier, R.B.; Mitnick, H.; Bloomgarden, D.; Weissman, G. Effect of bee venom on experimental arthritis. Ann. Rheum. Dis., 1973, 32, 466-469.
55. Park, H.J.; Lee, S.H.; Son, D.J.; Oh, K.W.; Kim, K.H.; Song, H.S.; Kim, G.J.; Oh, G.T.; Yoon, D.Y.; Hong, J.T. Antiarthritic effect of bee venom: inhibition of inflammationmediator generation by suppression of NF-kappaB through interaction with the p50 subunit. Arthritis. Rheum., 2004, 50, 3504-3515.
56. Couch, T.L.; Benton, A.W. The effect of the venom of the honey bee, Apis mellifera, on the adrenocortical response of the adult male rat. Toxicon, 1972, 10, 55-62.
57. Vick, J.A.; Shipman, W.H. Effects of whole bee venom and itsfractions (apamin and melittin) on plasma cortisol levels in the dog. Toxicon, 1972, 10, 377.
58. Somerfield, A.D.; Stach, J.L.; Mraz, C.; Gervais, F.; Skamene, E. Bee venom melittin blocks neutrophil O2 - production. Inflammation, 1986, 10, 175-182.
59. Jang, H.S.; Chung, H.S.; KO Shin, J.S.; Shin, M.K.; Hong, M.C.; Kim, Y.; Min, B.I.; Bae, H. Microarray analysis of gene expression profiles in response to treatment with bee venom inlipopolysaccharide activated RAW 264.7 cells. J. Ethnopharmacol., 2009, 121, 213-220.
60. Stuhlmeier, K.M. Apis mellifera venom and melittin block neither NF-kappaB-p50-DNA interactions nor the activation of NFkappaB, instead they acivate the transcriptin of proinflammatory genes and the release of reactive oxygen intermediates. J. Immunol., 2007, 179, 655-664.
61. Maberly, F.H. Brief notes on the treatment of rheumatism by bee stings. Lancet, 1910, 2, 235-237.
62. Kroner, J.; Lintz, R.; Tyndall, M.; Andersen, L.; Nicholls, E.E. The treatment of rheumatoid arthritis with an injectable form of bee venom. Ann. Intern. Med., 1938, 11, 1077-1083.
63. Steigerwaldt, F.; Mathies, H.; Damrau, F. Standardized bee venom therapy of arthritis. Controlled study of 50 cases with 84% benefit. Ind. Med. Surg., 1966, 35, 1045-1049.
64. Kwon YB, Kim JH, Yoon JH, Lee JD, Han HJ, Mar WC, Beitz AJ, Lee JH. The analgesic efficacy of bee venom acupuncture for knee osteoarthritis: a comparative study with needle acupuncture. Amer. J. Chin. Med., 2001, 29, 187-199.
65. Nicholls, E.E. Rheumatoid arthritis. Treatment with the sting of the honey bee. NY state J. Med., 1938, 38, 1218-12121.
66. Hollander, J. Bee venom in the treatment of chronic arthritis. Am. J. Med. Sci., 1941, 201, 796-801.
67. Hauser, R.; Daguio, M.; Hauser, M.; Kirchmann, A.; Skinkis, C. Bee venom therapy for multiple sclerosis. Altern. Complemen. Ther., 2001, 2, 37-45.
68. Wesselius, T.; Heersma, D.J.; Mostert, J.P.; Heerings, M.; Admiral- Belloul, F.; Talebian, A.; van Buchem, M.A.; de Keyser, J. A randomized crossover study on bee stingtherapy for multiple sclerosis. Neurology, 2005, 65, 1-5.