Ant venom immunotherapy: A double-blind, placebo-controlled, crossover trial

Lancet

Volumn 361, Issue 9362, 2003, Pages 1001-1006

  Brown, Simon G A ^a,b   Wiese, Michael D ^a   Blackman, Konrad E ^a   Heddle, Robert J ^b  

^a ROYAL HOBART HOSPITAL   (Australia)

^b FLINDERS UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANT VENOM; PLACEBO;

ADULT; ANAPHYLAXIS; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG HYPERSENSITIVITY; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPOTENSION; IMMUNOTHERAPY; INSECT STING; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RESUSCITATION; TREATMENT INDICATION; URTICARIA;

EID: 0037460793     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(03)12827-9     Document Type: Article

References (26)

1. Ogata K., Taylor R.W. Ants of the genus Myrmecia fabricus a preliminary review and key to the named species (Hymenoptera: Formidicae: Myrmeciinae). J Nat Hist. 25:1991;1623-1673.
2. Street M.D., Donovan G.R., Baldo B.A., Sutherland S. Immediate allergic reactions to Myrmecia ant stings: immunochemical analysis of Myrmecia venoms. Clin Exp Allergy. 24:1994;590-597.
3. Brown S.G., Franks R.W., Baldo B.A., Heddle R.J. Prevalence, severity, and natural history of jack jumper ant venom allergy in Tasmania. J Allergy Clin Immunol. 111:2003;187-192.
4. Douglas R., Weiner J., Abrahamson M., O'Hehir R. Prevalence of severe ant venom allergy in southeastern Australia. J Allergy Clin Immunol. 101:1998;129-131.
5. Brown S.G., Wu Q.X., Kelsall G.R., Heddle R.J., Baldo B.A. Fatal anaphylaxis following jack jumper ant sting in southern Tasmania. Med J Aust. 175:2001;644-647.
6. Hunt K.J., Valentine M.D., Sobotka A.K., Benton A.W., Amodio F.J., Lichtenstein L.M. A controlled trial of immunotherapy in insect hypersensitivity. N Engl J Med. 299:1978;157-161.
7. Muller U., Thurnheer U., Patrizzi R., Spiess J., Hoigne R. Immunotherapy in bee sting hypersensitivity: bee venom versus wholebody extract. Allergy. 34:1979;369-378.
8. Muller U. Insect sting allergy: clinical picture, diagnosis, and treatment. 1990;Gustav Fischer Verlag, New York.
9. Freeman T.M., Hylander R., Ortiz A., Martin M.E. Imported fire ant immunotherapy: effectiveness of whole body extracts. J Allergy Clin Immunol. 90:1992;210-215.
10. Tankersley M.S., Walker R.L., Butler W.K., Hagan L.L., Napoli D.C., Freeman T.M. Safety and efficacy of an imported fire ant rush immunotherapy protocol with and without prophylactic treatment. J Allergy Clin Immunol. 109:2002;556-562.
11. Weiner J.M., Baldo B.A., Donovan G.R., Sutherland S.K. Allergy to jumper ant (Myrmecia pilosula) stings in south-eastern Australia. Ann Allergy Asthma Immunol. 74:1995;60.
12. Goldberg A., Confino-Cohen R. A simple device for deliberate Hymenoptera sting challenge. J Allergy Clin Immunol. 100:1997;139-141.
13. van der Linden P.W., Hack C.E., Struyvenberg A., van der Zwan J.K. Insect-sting challenge in 324 subjects with a previous anaphylactic reaction: current criteria for insect-venom hypersensitivity do not predict the occurrence and the severity of anaphylaxis. J Allergy Clin Immunol. 94:1994;151-159.
14. Golden D.B., Kagey-Sobotka A., Norman P.S., Hamilton R.G., Lichtenstein L.M. Insect sting allergy with negative venom skin test responses. J Allergy Clin Immunol. 107:2001;897-901.
15. Schuberth K.C., Lichtenstein L.M., Kagey-Sobotka A., Szklo M., Kwiterovich K.A., Valentine M.D. Epidemiologic study of insect allergy in children. II. Effect of accidental stings in allergic children. J Pediatr. 102:1983;361-365.
16. Blaauw P.J., Smithuis O.L., Elbers A.R. The value of an in-hospital insect sting challenge as a criterion for application or omission of venom immunotherapy. J Allergy Clin Immunol. 98:1996;39-47.
17. van der Linden P.W., Struyvenberg A., Kraaijenhagen R.J., Hack C.E., van der Zwan J.K. Anaphylactic shock after insect-sting challenge in 138 persons with a previous insect-sting reaction. Ann Intern Med. 118:1993;161-168.
18. Smith P.L., Kagey-Sobotka A., Bleecker E.R., et al. Physiologic manifestations of human anaphylaxis. J Clin Invest. 66:1980;1072-1080.
19. Update on the emergency medical treatment of anaphylactic reactions for first medical responders and for community nurses. Emerg Med J. 18:2001;393-395.
20. Reisman R.E., Dvorin D.J., Randolph C.C., Georgitis J.W. Stinging insect allergy: natural history and modification with venom immunotherapy. J Allergy Clin Immunol. 75:1985;735-740.
21. Parker J.L., Santrach P.J., Dahlberg M.J., Yunginger J.W. Evaluation of Hymenoptera-sting sensitivity with deliberate sting challenges: inadequacy of present diagnostic methods. J Allergy Clin Immunol. 69:1982;200-207.
22. Blaauw P.J., Smithuis L.O. The evaluation of the common diagnostic methods of hypersensitivity for bee and yellow jacket venom by means of an in-hospital insect sting. J Allergy Clin Immunol. 75:1985;556-562.
23. Kampelmacher M.J., van der Zwan J.C. Provocation test with a living insect as a diagnostic tool in systemic reactions to bee and wasp venom: a prospective study with emphasis on the clinical aspects. Clin Allergy. 17:1987;317-327.
24. Ludolph-Hauser D., Rueff F., Fries C., Schopf P., Przybilla B. Constitutively raised serum concentrations of mast-cell tryptase and severe anaphylactic reactions to Hymenoptera stings. Lancet. 357:2001;361-362.
25. Lockey R.F., Turkeltaub P.C., Olive E.S., Hubbard J.M., Baird-Warren I.A., Bukantz S.C. The Hymenoptera venom study. III: Safety of venom immunotherapy. J Allergy Clin Immunol. 86:1990;775-780.
26. Oude Elberink J.N., De Monchy J.G., Van Der Heide S., Guyatt G.H., Dubois A.E. Venom immunotherapy improves health-related quality of life in patients allergic to yellow jacket venom. J Allergy Clin Immunol. 110:2002;174-182.