Influence of bee venom immunotherapy on degranulation and leukotriene generation in human blood basophils

Clinical and Experimental Allergy

Volumn 26, Issue 10, 1996, Pages 1112-1118

  Jutel, Marek ^a,c   Muller U R ^a   Fricker, M ^a   Rihs, S ^b   Pichler, W J ^b   Dahinden, C ^a  

^a Spital Netz Bern   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c Medical Division   (Switzerland)

Author keywords

Basophil degranulation; Leukotriene formation; Venom immunotherapy

Indexed keywords

ALLERGEN; BEE VENOM; HISTAMINE; IMMUNOGLOBULIN E; LEUKOTRIENE C4; PHOSPHOLIPASE A2;

ARTICLE; BASOPHIL; CLINICAL ARTICLE; CLINICAL TRIAL; HISTAMINE RELEASE; HUMAN; HUMAN CELL; IMMUNOTHERAPY; INSECT ALLERGY; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; BASOPHILS; BEE VENOMS; CYTOPLASMIC GRANULES; HISTAMINE RELEASE; HUMANS; IMMUNOTHERAPY; LEUKOTRIENE C4; LEUKOTRIENES; PHOSPHOLIPASES A; PROTEIN BINDING; RECEPTORS, IGE; TIME FACTORS;

EID: 0029850382     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.1996.tb00496.x     Document Type: Article

References (22)

1. Lichtenstein LM, Valentine MD, Sobotka AK. A case for venom treatment in anaphylactie sensitivity to hymenoptera sting. N Engl J Med 1974; 290:1223-7.
2. Hunt KJ, Valentine MD, Sobotka AK et al. A controlled trial of immunotherapy in insect hypersensitivity. N Engl J Med 1978; 299:157-61.
3. Müller U, Thurnheer U, Patrizzi R, Spiess J, Hoigne R. Immunotherapy in bee sting hypersensitivity. Bee venom versus whole body extract. Allergy 1979; 34:369 78.
4. Van De Zwan JC, Flinterman J, Jankowski IG, Kerchaert JAM. Hyposensitisation to wasp venoms in six hours. Br Med J 1983; 287:1329-31.
5. Bernstein DI, Mittman RJ. Kagen SL et al. Clinical and immunologic studies of rapid venom immunotherapy in hymenoptera sensitive patients. J All Clin Immunol 1989; 84:951-9.
6. Birnbaum J, Charpin D, Vervloet D. Rapid hymenoptera venom immunotherapy: comparative safety of three protocols. Clin Exp Allergy 1993; 23:226 30.
7. Skrbic D. Unpublished thesis. Bern 1994.
8. Hoffman DR, Jacobson RS. Allergens in hymenoptera venoms XII: how much protein is in a sting. Ann Allergy 1984; 50:276 8.
9. Mueller HL. Diagnosis and treatment of insect sensitivity. J Asthma Res 1966; 3:331 3.
10. Müller U. Insect sting allergy. Clinical picture, diagnosis and treatment New York: Fisher, 1990.
11. Held W, Stucki M, Heusser C, Blaser K. Production of human antibodies to bee venom phospholipase A2 in vitro. Scand J Immunol 1989; 29:203 11.
12. Riske F, Hakimi J, Mallamaci M et al. High affinity human IgE receptor (Fc∈RI). J Biol Chem 1991; 266:11245 52.
13. Hugly TE, Gerard C. Kawahara M et al. Isolation of three separate anaphylatoxins from complement-activated human serum. Mol Cell Biochem 1981; 41:203 12.
14. Kurimoto Y, De Week AL, Dahinden CA. Interleukin-3 dependent mediator release in basophils triggered by C5a. J Exp Med 1989; 170:467 75.
15. Bischoff SC, Dahinden CA. Effect of nerve growth factor on the release of inflammatory mediators by mature human basophils. Blood 1992; 79:2662 9.
16. Lichtenstein LM, Sobotka AK. Immunotherapy for insect sting allergy. ACI News 1989; 12:39 42.
17. Thurnheer U, Müller U, Stoller R, Lanner A, Hoigne R. Venom immunotherapy in hymenoptera sting allergy. Allergy 1983; 38:465 75.
18. Müller U, Helbling A, Bishof M. Predictive value of venom specific IgE, IgG and IgG subclass antibodies in patients on immunotherapy with honey bee venom. Allergy 1989; 44:412 8.
19. Jutel M, Skrbic D. Urwyler A et al. Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-γ secretion in specific allergen stimulated T-cell cultures. Immuno 1995; 154:4187 94.
20. Jntel M, Skrbic DA, Pichler WJ, Müller U. Ultra-rush bee venom immunotherapy does not reduce cutancous Wheal responses to bee venom and codeine phosphate. Clin Exp Allergy 1996; 25:1205 1210.
21. Stephan V, Kühr J, Urbanek R. Relevance of basophil histamine release changes during venom immunotherapy. Allergy 1989; 44:453 9.
22. Oettgen HC, Martin TR. Wynshaw-Boris A et al. Active anaphylaxis in IgE-deficient mice. Nature 1994; 370:367 9.