Superior biologic activity of the recombinant bee venom allergen hyaluronidase expressed in baculovirus-infected insect cells as compared with Escherichia coli

Journal of Allergy and Clinical Immunology

Volumn 101, Issue 5, 1998, Pages 691-698

  Soldatova, Lyudmila N ^a   Crameri, Reto ^b   Gmachl, Michael ^c   Kemeny, David M ^d   Schmidt, Margit ^e   Weber, Margrit ^a   Mueller, Ulrich R ^a,f  

^a UNIVERSITY OF BERN   (Switzerland)

^b SWISS INSTITUTE OF ALLERGY AND ASTHMA RESEARCH SIAF   (Switzerland)

^c Institute of Molecular Biology Salzburg   (Austria)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e EAST CAROLINA UNIVERSITY   (United States)

^f Spital Netz Bern   (Switzerland)

Author keywords

Baculovirus; Bee venom allergy; Enzymatic activity; Hyaluronidase; Recombinant allergens; Specific IgE

Indexed keywords

ALLERGEN; BEE VENOM; HYALURONIDASE; IMMUNOGLOBULIN E; RECOMBINANT PROTEIN;

ALLERGY; ANIMAL CELL; ARTICLE; BACULOVIRUS; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME CONFORMATION; ESCHERICHIA COLI; EUKARYOTIC CELL; GENE EXPRESSION SYSTEM; HUMAN; IMMUNOREACTIVITY; NONHUMAN; PRIORITY JOURNAL;

EID: 0031982094     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(98)70179-4     Document Type: Article

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