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Volumn 39, Issue 10, 2011, Pages 961-968

Deciphering transcriptional control mechanisms in hematopoiesis-the impact of high-throughput sequencing technologies

Author keywords

[No Author keywords available]

Indexed keywords

STAT3 PROTEIN; STAT4 PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR RUNX1;

EID: 80052855941     PISSN: 0301472X     EISSN: 18732399     Source Type: Journal    
DOI: 10.1016/j.exphem.2011.07.005     Document Type: Review
Times cited : (7)

References (70)
  • 1
    • 39149095636 scopus 로고    scopus 로고
    • SnapShot: hematopoiesis
    • Orkin S.H., Zon L.I. SnapShot: hematopoiesis. Cell 2008, 132:712.
    • (2008) Cell , vol.132 , pp. 712
    • Orkin, S.H.1    Zon, L.I.2
  • 2
    • 74049165069 scopus 로고    scopus 로고
    • Ontogeny of haematopoiesis: recent advances and open questions
    • Ottersbach K., Smith A., Wood A., Gottgens B. Ontogeny of haematopoiesis: recent advances and open questions. Br J Haematol 2010, 148:343-355.
    • (2010) Br J Haematol , vol.148 , pp. 343-355
    • Ottersbach, K.1    Smith, A.2    Wood, A.3    Gottgens, B.4
  • 3
    • 33747196725 scopus 로고    scopus 로고
    • Multilineage transcriptional priming and determination of alternate hematopoietic cell fates
    • Laslo P., Spooner C.J., Warmflash A., et al. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell 2006, 126:755-766.
    • (2006) Cell , vol.126 , pp. 755-766
    • Laslo, P.1    Spooner, C.J.2    Warmflash, A.3
  • 4
    • 0032125697 scopus 로고    scopus 로고
    • Regulation of eosinophil-specific gene expression by a C/EBP-Ets complex and GATA-1
    • McNagny K.M., Sieweke M.H., Doderlein G., Graf T., Nerlov C. Regulation of eosinophil-specific gene expression by a C/EBP-Ets complex and GATA-1. EMBO J 1998, 17:3669-3680.
    • (1998) EMBO J , vol.17 , pp. 3669-3680
    • McNagny, K.M.1    Sieweke, M.H.2    Doderlein, G.3    Graf, T.4    Nerlov, C.5
  • 5
    • 0032146794 scopus 로고    scopus 로고
    • PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors
    • Nerlov C., Graf T. PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors. Genes Dev 1998, 12:2403-2412.
    • (1998) Genes Dev , vol.12 , pp. 2403-2412
    • Nerlov, C.1    Graf, T.2
  • 6
    • 0032145528 scopus 로고    scopus 로고
    • Distinct C/EBP functions are required for eosinophil lineage commitment and maturation
    • Nerlov C., McNagny K.M., Doderlein G., Kowenz-Leutz E., Graf T. Distinct C/EBP functions are required for eosinophil lineage commitment and maturation. Genes Dev 1998, 12:2413-2423.
    • (1998) Genes Dev , vol.12 , pp. 2413-2423
    • Nerlov, C.1    McNagny, K.M.2    Doderlein, G.3    Kowenz-Leutz, E.4    Graf, T.5
  • 7
    • 70349728484 scopus 로고    scopus 로고
    • A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates
    • Spooner C.J., Cheng J.X., Pujadas E., Laslo P., Singh H. A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates. Immunity 2009, 31:576-586.
    • (2009) Immunity , vol.31 , pp. 576-586
    • Spooner, C.J.1    Cheng, J.X.2    Pujadas, E.3    Laslo, P.4    Singh, H.5
  • 8
    • 33847678449 scopus 로고    scopus 로고
    • Early decisions in lymphoid development
    • Ye M., Graf T. Early decisions in lymphoid development. Curr Opin Immunol 2007, 19:123-128.
    • (2007) Curr Opin Immunol , vol.19 , pp. 123-128
    • Ye, M.1    Graf, T.2
  • 9
    • 33846622099 scopus 로고    scopus 로고
    • Transcription factors in myeloid development: balancing differentiation with transformation
    • Rosenbauer F., Tenen D.G. Transcription factors in myeloid development: balancing differentiation with transformation. Nat Rev Immunol 2007, 7:105-117.
    • (2007) Nat Rev Immunol , vol.7 , pp. 105-117
    • Rosenbauer, F.1    Tenen, D.G.2
  • 10
    • 34250212629 scopus 로고    scopus 로고
    • The transcriptional regulation of B cell lineage commitment
    • Nutt S.L., Kee B.L. The transcriptional regulation of B cell lineage commitment. Immunity 2007, 26:715-725.
    • (2007) Immunity , vol.26 , pp. 715-725
    • Nutt, S.L.1    Kee, B.L.2
  • 11
    • 0034684615 scopus 로고    scopus 로고
    • Mouse models in the study of the Ets family of transcription factors
    • Bartel F.O., Higuchi T., Spyropoulos D.D. Mouse models in the study of the Ets family of transcription factors. Oncogene 2000, 19:6443-6454.
    • (2000) Oncogene , vol.19 , pp. 6443-6454
    • Bartel, F.O.1    Higuchi, T.2    Spyropoulos, D.D.3
  • 12
    • 0034303586 scopus 로고    scopus 로고
    • Diversification of haematopoietic stem cells to specific lineages
    • Orkin S.H. Diversification of haematopoietic stem cells to specific lineages. Nat Rev Genet 2000, 1:57-64.
    • (2000) Nat Rev Genet , vol.1 , pp. 57-64
    • Orkin, S.H.1
  • 13
    • 58549117664 scopus 로고    scopus 로고
    • Transcriptional regulatory networks in haematopoiesis
    • Miranda-Saavedra D., Gottgens B. Transcriptional regulatory networks in haematopoiesis. Curr Opin Genet Dev 2008, 18:530-535.
    • (2008) Curr Opin Genet Dev , vol.18 , pp. 530-535
    • Miranda-Saavedra, D.1    Gottgens, B.2
  • 14
    • 77954842706 scopus 로고    scopus 로고
    • Gene regulatory networks governing haematopoietic stem cell development and identity
    • Pimanda J.E., Gottgens B. Gene regulatory networks governing haematopoietic stem cell development and identity. Int J Dev Biol 2010, 54:1201-1211.
    • (2010) Int J Dev Biol , vol.54 , pp. 1201-1211
    • Pimanda, J.E.1    Gottgens, B.2
  • 15
    • 79952534189 scopus 로고    scopus 로고
    • Regulation of chromatin by histone modifications
    • Bannister A.J., Kouzarides T. Regulation of chromatin by histone modifications. Cell Res 2011, 21:381-395.
    • (2011) Cell Res , vol.21 , pp. 381-395
    • Bannister, A.J.1    Kouzarides, T.2
  • 16
    • 79551587102 scopus 로고    scopus 로고
    • Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
    • Koh K.P., Yabuuchi A., Rao S., et al. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell 2011, 8:200-213.
    • (2011) Cell Stem Cell , vol.8 , pp. 200-213
    • Koh, K.P.1    Yabuuchi, A.2    Rao, S.3
  • 17
    • 79956323623 scopus 로고    scopus 로고
    • Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
    • Ficz G., Branco M.R., Seisenberger S., et al. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 2011, 473:398-402.
    • (2011) Nature , vol.473 , pp. 398-402
    • Ficz, G.1    Branco, M.R.2    Seisenberger, S.3
  • 18
    • 77957970301 scopus 로고    scopus 로고
    • Epigenetic modifications and human disease
    • Portela A., Esteller M. Epigenetic modifications and human disease. Nat Biotechnol 2010, 28:1057-1068.
    • (2010) Nat Biotechnol , vol.28 , pp. 1057-1068
    • Portela, A.1    Esteller, M.2
  • 19
    • 4644220954 scopus 로고    scopus 로고
    • MLL: a histone methyltransferase disrupted in leukemia
    • Hess J.L. MLL: a histone methyltransferase disrupted in leukemia. Trends Mol Med 2004, 10:500-507.
    • (2004) Trends Mol Med , vol.10 , pp. 500-507
    • Hess, J.L.1
  • 20
    • 49749104565 scopus 로고    scopus 로고
    • Roles of the histone acetyltransferase monocytic leukemia zinc finger protein in normal and malignant hematopoiesis
    • Katsumoto T., Yoshida N., Kitabayashi I. Roles of the histone acetyltransferase monocytic leukemia zinc finger protein in normal and malignant hematopoiesis. Cancer Sci 2008, 99:1523-1527.
    • (2008) Cancer Sci , vol.99 , pp. 1523-1527
    • Katsumoto, T.1    Yoshida, N.2    Kitabayashi, I.3
  • 21
    • 41949095010 scopus 로고    scopus 로고
    • Long-range regulation of alpha globin gene expression during erythropoiesis
    • Higgs D.R., Wood W.G. Long-range regulation of alpha globin gene expression during erythropoiesis. Curr Opin Hematol 2008, 15:176-183.
    • (2008) Curr Opin Hematol , vol.15 , pp. 176-183
    • Higgs, D.R.1    Wood, W.G.2
  • 22
    • 39049113889 scopus 로고    scopus 로고
    • Three-dimensional organization of gene expression in erythroid cells
    • de Laat W., Klous P., Kooren J., et al. Three-dimensional organization of gene expression in erythroid cells. Curr Top Dev Biol 2008, 82:117-139.
    • (2008) Curr Top Dev Biol , vol.82 , pp. 117-139
    • de Laat, W.1    Klous, P.2    Kooren, J.3
  • 23
    • 70449696134 scopus 로고    scopus 로고
    • Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression
    • Cheng Y., Wu W., Kumar S.A., et al. Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. Genome Res 2009, 19:2172-2184.
    • (2009) Genome Res , vol.19 , pp. 2172-2184
    • Cheng, Y.1    Wu, W.2    Kumar, S.A.3
  • 24
    • 77955131763 scopus 로고    scopus 로고
    • Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells
    • Kassouf M.T., Hughes J.R., Taylor S., et al. Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells. Genome Res 2010, 20:1064-1083.
    • (2010) Genome Res , vol.20 , pp. 1064-1083
    • Kassouf, M.T.1    Hughes, J.R.2    Taylor, S.3
  • 25
    • 76149089221 scopus 로고    scopus 로고
    • The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation
    • Soler E., Andrieu-Soler C., de Boer E., et al. The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation. Genes Dev 2010, 24:277-289.
    • (2010) Genes Dev , vol.24 , pp. 277-289
    • Soler, E.1    Andrieu-Soler, C.2    de Boer, E.3
  • 26
    • 70449675049 scopus 로고    scopus 로고
    • Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy
    • Fujiwara T., O'Geen H., Keles S., et al. Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy. Mol Cell 2009, 36:667-681.
    • (2009) Mol Cell , vol.36 , pp. 667-681
    • Fujiwara, T.1    O'Geen, H.2    Keles, S.3
  • 27
    • 78650563327 scopus 로고    scopus 로고
    • Building multifunctionality into a complex containing master regulators of hematopoiesis
    • Fujiwara T., Lee H.Y., Sanalkumar R., Bresnick E.H. Building multifunctionality into a complex containing master regulators of hematopoiesis. Proc Natl Acad Sci U S A 2010, 107:20429-20434.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 20429-20434
    • Fujiwara, T.1    Lee, H.Y.2    Sanalkumar, R.3    Bresnick, E.H.4
  • 29
    • 18444415449 scopus 로고    scopus 로고
    • Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors
    • Gottgens B., Nastos A., Kinston S., et al. Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors. EMBO J 2002, 21:3039-3050.
    • (2002) EMBO J , vol.21 , pp. 3039-3050
    • Gottgens, B.1    Nastos, A.2    Kinston, S.3
  • 30
    • 14644412924 scopus 로고    scopus 로고
    • Genome-wide identification of cis-regulatory sequences controlling blood and endothelial development
    • Donaldson I.J., Chapman M., Kinston S., et al. Genome-wide identification of cis-regulatory sequences controlling blood and endothelial development. Hum Mol Genet 2005, 14:595-601.
    • (2005) Hum Mol Genet , vol.14 , pp. 595-601
    • Donaldson, I.J.1    Chapman, M.2    Kinston, S.3
  • 31
    • 77955502318 scopus 로고    scopus 로고
    • Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate
    • Narula J., Smith A.M., Gottgens B., Igoshin O.A. Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate. PLoS Comput Biol 2010, 6:e1000771.
    • (2010) PLoS Comput Biol , vol.6
    • Narula, J.1    Smith, A.M.2    Gottgens, B.3    Igoshin, O.A.4
  • 32
    • 36749094041 scopus 로고    scopus 로고
    • Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development
    • Pimanda J.E., Ottersbach K., Knezevic K., et al. Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development. Proc Natl Acad Sci U S A 2007, 104:17692-17697.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 17692-17697
    • Pimanda, J.E.1    Ottersbach, K.2    Knezevic, K.3
  • 33
    • 67349199007 scopus 로고    scopus 로고
    • Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors
    • Landry J.R., Bonadies N., Kinston S., et al. Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors. Blood 2009, 113:5783-5792.
    • (2009) Blood , vol.113 , pp. 5783-5792
    • Landry, J.R.1    Bonadies, N.2    Kinston, S.3
  • 34
    • 58149378446 scopus 로고    scopus 로고
    • Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code
    • Pimanda J.E., Chan W.Y., Wilson N.K., et al. Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code. Blood 2008, 112:4512-4522.
    • (2008) Blood , vol.112 , pp. 4512-4522
    • Pimanda, J.E.1    Chan, W.Y.2    Wilson, N.K.3
  • 35
    • 0032190190 scopus 로고    scopus 로고
    • Expression of the LIM-homeobox gene LH2 generates immortalized steel factor-dependent multipotent hematopoietic precursors
    • Pinto do O.P., Kolterud A., Carlsson L. Expression of the LIM-homeobox gene LH2 generates immortalized steel factor-dependent multipotent hematopoietic precursors. EMBO J 1998, 17:5744-5756.
    • (1998) EMBO J , vol.17 , pp. 5744-5756
    • Pinto do, O.P.1    Kolterud, A.2    Carlsson, L.3
  • 36
    • 67049108075 scopus 로고    scopus 로고
    • The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development
    • Wilson N.K., Miranda-Saavedra D., Kinston S., et al. The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development. Blood 2009, 113:5456-5465.
    • (2009) Blood , vol.113 , pp. 5456-5465
    • Wilson, N.K.1    Miranda-Saavedra, D.2    Kinston, S.3
  • 37
    • 77957348625 scopus 로고    scopus 로고
    • Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators
    • Wilson N.K., Foster S.D., Wang X., et al. Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators. Cell Stem Cell 2010, 7:532-544.
    • (2010) Cell Stem Cell , vol.7 , pp. 532-544
    • Wilson, N.K.1    Foster, S.D.2    Wang, X.3
  • 38
    • 78751625306 scopus 로고    scopus 로고
    • Nuclear adaptor Ldb1 regulates a transcriptional program essential for the maintenance of hematopoietic stem cells
    • Li L., Jothi R., Cui K., et al. Nuclear adaptor Ldb1 regulates a transcriptional program essential for the maintenance of hematopoietic stem cells. Nat Immunol 2011, 12:129-136.
    • (2011) Nat Immunol , vol.12 , pp. 129-136
    • Li, L.1    Jothi, R.2    Cui, K.3
  • 39
    • 79955137160 scopus 로고    scopus 로고
    • A compendium of genome-wide hematopoietic transcription factor maps supports the identification of gene regulatory control mechanisms
    • Hannah R., Joshi A., Wilson N.K., Kinston S., Gottgens B. A compendium of genome-wide hematopoietic transcription factor maps supports the identification of gene regulatory control mechanisms. Exp Hematol 2011, 39:531-541.
    • (2011) Exp Hematol , vol.39 , pp. 531-541
    • Hannah, R.1    Joshi, A.2    Wilson, N.K.3    Kinston, S.4    Gottgens, B.5
  • 40
    • 79951828280 scopus 로고    scopus 로고
    • GABP controls a critical transcription regulatory module that is essential for maintenance and differentiation of hematopoietic stem/progenitor cells
    • Yu S., Cui K., Jothi R., et al. GABP controls a critical transcription regulatory module that is essential for maintenance and differentiation of hematopoietic stem/progenitor cells. Blood 2011, 117:2166-2178.
    • (2011) Blood , vol.117 , pp. 2166-2178
    • Yu, S.1    Cui, K.2    Jothi, R.3
  • 41
    • 78651486442 scopus 로고    scopus 로고
    • Densely interconnected transcriptional circuits control cell states in human hematopoiesis
    • Novershtern N., Subramanian A., Lawton L.N., et al. Densely interconnected transcriptional circuits control cell states in human hematopoiesis. Cell 2011, 144:296-309.
    • (2011) Cell , vol.144 , pp. 296-309
    • Novershtern, N.1    Subramanian, A.2    Lawton, L.N.3
  • 42
    • 78650991254 scopus 로고    scopus 로고
    • Dynamic combinatorial interactions of RUNX1 and cooperating partners regulates megakaryocytic differentiation in cell line models
    • Pencovich N., Jaschek R., Tanay A., Groner Y. Dynamic combinatorial interactions of RUNX1 and cooperating partners regulates megakaryocytic differentiation in cell line models. Blood 2011, 117:e1-e14.
    • (2011) Blood , vol.117
    • Pencovich, N.1    Jaschek, R.2    Tanay, A.3    Groner, Y.4
  • 43
    • 79955883317 scopus 로고    scopus 로고
    • Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators
    • Tijssen M.R., Cvejic A., Joshi A., et al. Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev Cell 2011, 20:597-609.
    • (2011) Dev Cell , vol.20 , pp. 597-609
    • Tijssen, M.R.1    Cvejic, A.2    Joshi, A.3
  • 44
    • 0025817426 scopus 로고
    • Immunoglobulin gene transcription
    • Staudt L.M., Lenardo M.J. Immunoglobulin gene transcription. Annu Rev Immunol 1991, 9:373-398.
    • (1991) Annu Rev Immunol , vol.9 , pp. 373-398
    • Staudt, L.M.1    Lenardo, M.J.2
  • 45
    • 0024953872 scopus 로고
    • Developmental regulation of the TCR alpha delta locus
    • Winoto A., Baltimore D. Developmental regulation of the TCR alpha delta locus. Cold Spring Harb Symp Quant Biol 1989, 54(Pt 1):87-92.
    • (1989) Cold Spring Harb Symp Quant Biol , vol.54 , Issue.PART 1 , pp. 87-92
    • Winoto, A.1    Baltimore, D.2
  • 46
    • 77953763449 scopus 로고    scopus 로고
    • A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate
    • Lin Y.C., Jhunjhunwala S., Benner C., et al. A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate. Nat Immunol 2010, 11:635-643.
    • (2010) Nat Immunol , vol.11 , pp. 635-643
    • Lin, Y.C.1    Jhunjhunwala, S.2    Benner, C.3
  • 47
    • 54549103162 scopus 로고    scopus 로고
    • Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression
    • Liao W., Schones D.E., Oh J., et al. Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression. Nat Immunol 2008, 9:1288-1296.
    • (2008) Nat Immunol , vol.9 , pp. 1288-1296
    • Liao, W.1    Schones, D.E.2    Oh, J.3
  • 48
    • 77953917067 scopus 로고    scopus 로고
    • Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation
    • Wei L., Vahedi G., Sun H.W., et al. Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation. Immunity 2010, 32:840-851.
    • (2010) Immunity , vol.32 , pp. 840-851
    • Wei, L.1    Vahedi, G.2    Sun, H.W.3
  • 49
    • 45749101727 scopus 로고    scopus 로고
    • Induction and effector functions of T(H)17 cells
    • Bettelli E., Korn T., Oukka M., Kuchroo V.K. Induction and effector functions of T(H)17 cells. Nature 2008, 453:1051-1057.
    • (2008) Nature , vol.453 , pp. 1051-1057
    • Bettelli, E.1    Korn, T.2    Oukka, M.3    Kuchroo, V.K.4
  • 50
    • 34247555353 scopus 로고    scopus 로고
    • Differentiation and function of Th17 T cells
    • Stockinger B., Veldhoen M. Differentiation and function of Th17 T cells. Curr Opin Immunol 2007, 19:281-286.
    • (2007) Curr Opin Immunol , vol.19 , pp. 281-286
    • Stockinger, B.1    Veldhoen, M.2
  • 51
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver C.T., Hatton R.D., Mangan P.R., Harrington L.E. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol 2007, 25:821-852.
    • (2007) Annu Rev Immunol , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 52
    • 34247593586 scopus 로고    scopus 로고
    • STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
    • Yang X.O., Panopoulos A.D., Nurieva R., et al. STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J Biol Chem 2007, 282:9358-9363.
    • (2007) J Biol Chem , vol.282 , pp. 9358-9363
    • Yang, X.O.1    Panopoulos, A.D.2    Nurieva, R.3
  • 53
    • 77953293952 scopus 로고    scopus 로고
    • Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis
    • Durant L., Watford W.T., Ramos H.L., et al. Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis. Immunity 2010, 32:605-615.
    • (2010) Immunity , vol.32 , pp. 605-615
    • Durant, L.1    Watford, W.T.2    Ramos, H.L.3
  • 54
    • 58049220979 scopus 로고    scopus 로고
    • Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia
    • Guenther M.G., Lawton L.N., Rozovskaia T., et al. Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia. Genes Dev 2008, 22:3403-3408.
    • (2008) Genes Dev , vol.22 , pp. 3403-3408
    • Guenther, M.G.1    Lawton, L.N.2    Rozovskaia, T.3
  • 55
    • 63849220435 scopus 로고    scopus 로고
    • PML nuclear bodies in the pathogenesis of acute promyelocytic leukemia: active players or innocent bystanders?
    • Brown N.J., Ramalho M., Pedersen E.W., Moravcsik E., Solomon E., Grimwade D. PML nuclear bodies in the pathogenesis of acute promyelocytic leukemia: active players or innocent bystanders?. Front Biosci 2009, 14:1684-1707.
    • (2009) Front Biosci , vol.14 , pp. 1684-1707
    • Brown, N.J.1    Ramalho, M.2    Pedersen, E.W.3    Moravcsik, E.4    Solomon, E.5    Grimwade, D.6
  • 56
    • 76249101323 scopus 로고    scopus 로고
    • PML-RARalpha/RXR alters the epigenetic landscape in acute promyelocytic leukemia
    • Martens J.H., Brinkman A.B., Simmer F., et al. PML-RARalpha/RXR alters the epigenetic landscape in acute promyelocytic leukemia. Cancer Cell 2010, 17:173-185.
    • (2010) Cancer Cell , vol.17 , pp. 173-185
    • Martens, J.H.1    Brinkman, A.B.2    Simmer, F.3
  • 57
    • 79960032630 scopus 로고    scopus 로고
    • Cell of origin in AML: Susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex
    • Heuser M., Yun H., Berg T., et al. Cell of origin in AML: Susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex. Cancer Cell 2011, 20:39-52.
    • (2011) Cancer Cell , vol.20 , pp. 39-52
    • Heuser, M.1    Yun, H.2    Berg, T.3
  • 58
    • 79551528760 scopus 로고    scopus 로고
    • Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia
    • Bonadies N., Foster S.D., Chan W.I., et al. Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia. PLoS One 2011, 6:e16330.
    • (2011) PLoS One , vol.6
    • Bonadies, N.1    Foster, S.D.2    Chan, W.I.3
  • 59
    • 74549114755 scopus 로고    scopus 로고
    • A practical comparison of methods for detecting transcription factor binding sites in ChIP-seq experiments
    • Laajala T.D., Raghav S., Tuomela S., Lahesmaa R., Aittokallio T., Elo L.L. A practical comparison of methods for detecting transcription factor binding sites in ChIP-seq experiments. BMC Genomics 2009, 10:618.
    • (2009) BMC Genomics , vol.10 , pp. 618
    • Laajala, T.D.1    Raghav, S.2    Tuomela, S.3    Lahesmaa, R.4    Aittokallio, T.5    Elo, L.L.6
  • 60
    • 67649292737 scopus 로고    scopus 로고
    • Unlocking the secrets of the genome
    • Celniker S.E., Dillon L.A., Gerstein M.B., et al. Unlocking the secrets of the genome. Nature 2009, 459:927-930.
    • (2009) Nature , vol.459 , pp. 927-930
    • Celniker, S.E.1    Dillon, L.A.2    Gerstein, M.B.3
  • 61
    • 78650331647 scopus 로고    scopus 로고
    • Identification of functional elements and regulatory circuits by Drosophila modENCODE
    • Roy S., Ernst J., Kharchenko P.V., et al. Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science 2010, 330:1787-1797.
    • (2010) Science , vol.330 , pp. 1787-1797
    • Roy, S.1    Ernst, J.2    Kharchenko, P.V.3
  • 62
    • 52649097448 scopus 로고    scopus 로고
    • The Immunological Genome Project: networks of gene expression in immune cells
    • Heng T.S., Painter M.W. The Immunological Genome Project: networks of gene expression in immune cells. Nat Immunol 2008, 9:1091-1094.
    • (2008) Nat Immunol , vol.9 , pp. 1091-1094
    • Heng, T.S.1    Painter, M.W.2
  • 63
    • 77955172885 scopus 로고    scopus 로고
    • Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors
    • Adli M., Zhu J., Bernstein B.E. Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors. Nat Methods 2010, 7:615-618.
    • (2010) Nat Methods , vol.7 , pp. 615-618
    • Adli, M.1    Zhu, J.2    Bernstein, B.E.3
  • 64
    • 67651111994 scopus 로고    scopus 로고
    • Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program
    • Hoogenkamp M., Lichtinger M., Krysinska H., et al. Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program. Blood 2009, 114:299-309.
    • (2009) Blood , vol.114 , pp. 299-309
    • Hoogenkamp, M.1    Lichtinger, M.2    Krysinska, H.3
  • 65
    • 34250791291 scopus 로고    scopus 로고
    • Detection of in vivo protein-DNA interactions using DamID in mammalian cells
    • Vogel M.J., Peric-Hupkes D., van Steensel B. Detection of in vivo protein-DNA interactions using DamID in mammalian cells. Nat Protoc 2007, 2:1467-1478.
    • (2007) Nat Protoc , vol.2 , pp. 1467-1478
    • Vogel, M.J.1    Peric-Hupkes, D.2    van Steensel, B.3
  • 66
    • 77957776228 scopus 로고    scopus 로고
    • Systematic protein location mapping reveals five principal chromatin types in Drosophila cells
    • Filion G.J., van Bemmel J.G., Braunschweig U., et al. Systematic protein location mapping reveals five principal chromatin types in Drosophila cells. Cell 2010, 143:212-224.
    • (2010) Cell , vol.143 , pp. 212-224
    • Filion, G.J.1    van Bemmel, J.G.2    Braunschweig, U.3
  • 67
    • 0142215475 scopus 로고    scopus 로고
    • Global analysis of protein expression in yeast
    • Ghaemmaghami S., Huh W.K., Bower K., et al. Global analysis of protein expression in yeast. Nature 2003, 425:737-741.
    • (2003) Nature , vol.425 , pp. 737-741
    • Ghaemmaghami, S.1    Huh, W.K.2    Bower, K.3
  • 68
    • 77954927294 scopus 로고    scopus 로고
    • Stoichiometry of STAT3 and mitochondrial proteins: Implications for the regulation of oxidative phosphorylation by protein-protein interactions
    • Phillips D., Reilley M.J., Aponte A.M., et al. Stoichiometry of STAT3 and mitochondrial proteins: Implications for the regulation of oxidative phosphorylation by protein-protein interactions. J Biol Chem 2010, 285:23532-23536.
    • (2010) J Biol Chem , vol.285 , pp. 23532-23536
    • Phillips, D.1    Reilley, M.J.2    Aponte, A.M.3
  • 69
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
    • Heinz S., Benner C., Spann N., et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell 2010, 38:576-589.
    • (2010) Mol Cell , vol.38 , pp. 576-589
    • Heinz, S.1    Benner, C.2    Spann, N.3
  • 70
    • 79551605803 scopus 로고    scopus 로고
    • Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages
    • Palii C.G., Perez-Iratxeta C., Yao Z., et al. Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages. EMBO J 2011, 30:494-509.
    • (2011) EMBO J , vol.30 , pp. 494-509
    • Palii, C.G.1    Perez-Iratxeta, C.2    Yao, Z.3


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