Determination of ionization constant (pka) for poorly soluble drugs by using surfactants: A novel approach

Der Pharmacia Lettre

Volumn 3, Issue 4, 2011, Pages 183-192

  Ravichandiran, V ^a   Devarajan, V ^a   Masilamani, K ^a  

^a VELS INSTITUTE OF SCIENCE   (India)

Author keywords

Ionization constant (pKa); Poorly soluble drugs; Potentiometry; Spectrophotometry.; Surfactant

Indexed keywords

CARVEDILOL; CREMOPHOR; GLIPIZIDE; IBUPROFEN; LABRASOL; NIMESULIDE; POLOXAMER; POLYSORBATE 80; SURFACTANT; TOLBUTAMIDE;

ACIDIFICATION; ARTICLE; CRITICAL MICELLE CONCENTRATION; DISSOCIATION CONSTANT; DRUG SOLUBILITY; EQUILIBRIUM CONSTANT; HYDROPHILICITY; IONIZATION; IONIZATION CONSTANT; PH; PHYSICAL CHEMISTRY; POTENTIOMETRIC TITRATION; POTENTIOMETRY; PROTON TRANSPORT; SPECTROPHOTOMETRY; ULTRAVIOLET SPECTROSCOPY;

EID: 80052825748     PISSN: None     EISSN: 09755071     Source Type: Journal    
DOI: None     Document Type: Article

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