Effect of pH-sodium lauryl sulfate combination on solubilization of PG-300995 (an anti-HIV agent): A technical note

AAPS PharmSciTech

Volumn 5, Issue 3, 2004, Pages

  Jain, Akash ^a,b   Ran, Yingqing ^a   Yalkowsky, Samuel H ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b NONE   (United States)

Author keywords

Desolubilization; Micellization; pH; SLS; Solubilization; Surfactant

Indexed keywords

2 (2 THIOPHENYL) 4 AZABENZIMIDAZOLE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; DODECYL SULFATE SODIUM; PG 300995; UNCLASSIFIED DRUG; DRUG DERIVATIVE; SODIUM LAURETH SULFATE;

ARTICLE; CONTROLLED STUDY; DRUG SOLUBILITY; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; MICELLIZATION; PH; CHEMISTRY; DRUG COMBINATION; SOLUBILITY;

ANTI-HIV AGENTS; DRUG COMBINATIONS; HYDROGEN-ION CONCENTRATION; SODIUM DODECYL SULFATE; SOLUBILITY;

EID: 23144449959     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt050345     Document Type: Article

References (5)

1. Attwood D, Florence AT. Surfactant Systems. New York, NY: Chapman and Hall; 1983.
2. Martin A, Bustamante P, Chun AHC. Solubility and distribution phenomena. In: Physical Pharmacy. 4th ed. Philadelphia, PA: Lea & Febiger; 1993:212-250.
3. Yalkowsky SH. Solubilization by surfactants. In: Solubility and Solubilization in Aqueous Media. New York, NY: Oxford University Press; 1999:236-315.
4. Li P, Tabibi SE, Yalkowsky SH. Solubilization of ionized and un-ionized flavopiridol by ethanol and polysorbate 20. J Pharm Sci. 1999;88:507-509.
5. Stubbs C, Kanfer I. A stability indicating high-performance liquid chromatographic assay of erythromycin estolate in pharmaceutical dosage forms. Int J Pharm. 1990;63:113-119.