Identification of the absorbed components and metabolites in rat plasma after oral administration of Rhizoma Chuanxiong decoction by HPLC-ESI-MS/MS

Journal of Pharmaceutical and Biomedical Analysis

Volumn 56, Issue 5, 2011, Pages 1046-1056

  Zuo, Aihua ^a   Wang, Li ^a   Xiao, Hongbin ^a   Li, Limin ^b   Liu, Yuhong ^b   Yi, Jinhai ^b  

^a DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^b Sichuan Academy of Chinese Medicine Sciences   (China)

Author keywords

Absorbed components; HPLC ESI MS; Ligusticum chuanxiong; Metabolism; Rat plasma

Indexed keywords

4,7 DIHYDROXY 3 BUTYLPHTHALIDE; BUTYLIDENEPHTHALIDE; CHINESE DRUG; CYSTEINE; DICAFFEOYLQUINIC ACID; DRUG METABOLITE; FERULIC ACID; GLUCURONIC ACID; GLUTATHIONE; LEVISTOLIDE A; LIGUSTILIDE; NATURAL PRODUCT; NEOCNIDILIDE; RHIZOMA CHUANXIONG DECOCTION; SENKYUNOLIDE A; SENKYUNOLIDE B; SENKYUNOLIDE C; SENKYUNOLIDE D; SENKYUNOLIDE F; SENKYUNOLIDE G; SENKYUNOLIDE H; SENKYUNOLIDE I; SENKYUNOLIDE J; SENKYUNOLIDE M; SENKYUNOLIDE N; SENKYUNOLIDE Q; SULFURIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RAT; ULTRAVIOLET SPECTROSCOPY;

ADMINISTRATION, ORAL; ANIMALS; BLOOD CHEMICAL ANALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET; TANDEM MASS SPECTROMETRY;

EID: 80052811549     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.08.010     Document Type: Article

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