Analysis of the constituents in rat plasma after oral administration of Shexiang Baoxin pill by HPLC-ESI-MS/MS

Biomedical Chromatography

Volumn 23, Issue 12, 2009, Pages 1333-1343

  Jiang, Peng ^a   Liu, Ruihui ^a   Dou, Shengshan ^a   Liu, Lei ^a   Zhang, Weidong ^a,b   Chen, Zhongliang ^c   Xu, Ruilin ^c   Ding, Jianmi ^c  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c Shanghai Hutchison Pharmaceuticals Company   (China)

Author keywords

HPLC DAD MS MS; Metabolties; Rat plasma; Shexiang Baoxin pill

Indexed keywords

BODY FLUIDS; COLUMN CHROMATOGRAPHY; DIAGNOSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; PLANTS (BOTANY); RATS;

ACID WATERS; HPLC-DAD-MS/MS; ION-TRAP MASS SPECTROMETRY; LINEAR GRADIENTS; METABOLTIE; ORAL ADMINISTRATION; RAT PLASMA; SHEXIANG BAOXIN PILL; SYMMETRY C-18; TRADITIONAL CHINESE MEDICINE;

ELECTROSPRAY IONIZATION;

11 HYDROXYPROGESTERONE; 1BETA HYDROXYLBUFALIN; 3 EPIBUFALIN; ACETONITRILE; BUFALIN; CHENODEOXYCHOLIC ACID; CHINESE DRUG; CHOLIC ACID; CINOBUFAGIN; DEOXYCHOLIC ACID; DRUG METABOLITE; FORMIC ACID; GAMABUFOTALIN; GINSENOSIDE RA1; GINSENOSIDE RA2; GINSENOSIDE RB 1; GINSENOSIDE RB 2; GINSENOSIDE RB3; GINSENOSIDE RC; GINSENOSIDE RD; GINSENOSIDE RE; HYDROXYPROGESTERONE; HYODEOXYCHOLIC ACID; PROGESTERONE DERIVATIVE; RESIBUFAGINOL; SHEXIANG BAOXIN; SHEXIANG BAOXIN PILL; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION TRAP MASS SPECTROMETRY; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; QUANTITATIVE ASSAY; RAT; SOLID PHASE EXTRACTION; SPRAGUE DAWLEY RAT; VALIDATION PROCESS;

RATTUS;

EID: 71649087595     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1258     Document Type: Article

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