Cytosolic phospholipase A2 participates with TNF-α in the induction of apoptosis of human macrophages infected with Mycobacterium tuberculosis H37Ra

Journal of Immunology

Volumn 166, Issue 12, 2001, Pages 7469-7476

  Duan, L ^a   Gan, H ^a   Arm, J ^a   Remold, H G ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; PHOSPHOLIPASE A2; TUMOR NECROSIS FACTOR ALPHA; CYCLOHEXIMIDE; ENZYME INHIBITOR; IMMUNOLOGICAL ADJUVANT; ISOENZYME; PHOSPHOLIPASE A; PROTEIN SYNTHESIS INHIBITOR; TUBERCULOSTATIC AGENT;

APOPTOSIS; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MACROPHAGE; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TUBERCULOSIS; BIOSYNTHESIS; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; IMMUNOLOGY; MICROBIOLOGY; PHYSIOLOGY;

ADJUVANTS, IMMUNOLOGIC; ANTITUBERCULAR AGENTS; APOPTOSIS; ARACHIDONIC ACID; CYCLOHEXIMIDE; CYTOSOL; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; ISOENZYMES; MACROPHAGES; MYCOBACTERIUM TUBERCULOSIS; PHOSPHOLIPASES A; PROTEIN SYNTHESIS INHIBITORS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035874639     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.12.7469     Document Type: Article

References (48)

1. Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells
2. Macrophage phagocytosis of aging neutrophils in inflammation: Programmed cell death in the neutrophil leads to its recognition by macrophages
3. Apoptosis of human monocytes/macrophages in Mycobacterium tuberculosis infection
4. Programmed cell death of Mycobacterium avium serovar 4-infected human macrophages prevents the mycobacteria from spreading and induces mycobacterial growth inhibition by freshly added, uninfected macrophages
5. Activation of tuberculostatic macrophage functions by γ interferon, interleukin-4, and tumor necrosis factor
6. Role of tumor necrosis factor-α in mycobacteria-induced granuloma formation in tumor necrosis factor-α-deficient mice
7. Infection by Mycobacterium tuberculosis promotes human alveolar macrophage apoptosis
8. Apoptosis of Mycobacterium avium-infected macrophages is mediated by both tumour necrosis factor (TNF) and Fas, and involves the activation of caspases
9. The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
10. Apoptosis by death factor
11. Caspases: Enemies within
12. Cytochrome c an dATP-dependent formation of Apaf-1/ caspase-9 complex initiates an apoptotic protease cascade
13. The biochemistry of apoptosis
14. 2 superfamily of signal transduction enzymes
15. 2 causes TNF resistance in human leukemic cells
16. 2 in tumor necrosis factor-induced apoptosis
17. 2 in human melanoma tumor cells
18. 2 is crucial in the cytotoxic action of tumor necrosis factor
19. 2 in canine myocardium
20. 2 from macrophage-like P388D1 cells: Isolation and characterization
21. 2
22. 2+-dependent translocation domain with homology to PKC and GAP
23. 2-β
24. 2
25. 2
26. Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guerin
27. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
28. Potentiation of Fas-mediated apoptosis of murine granulosa cells by interferon-γ, tumor necrosis factor-α, and cycloheximide
29. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
30. 2 in cultured mast cells
31. Yama/CPP-32β, a mammalian homolog of CED-3 is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose)polymerase
32. Transient poly(ADP-ribosyl)ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis
33. 2 in eicosanoid generation
34. 2
35. 2 enzymes from P388D, macrophages and Chinese hamster ovary cells
36. 2 contains eight ankyrin motifs
37. An endotoxin-induced serum factor that causes necrosis of tumors
38. Recombinant human tumor necrosis factor-α: Effects on proliferation of normal and transformed cells in vitro
39. Involvement of prostaglandin-producing pathway in the cytotoxic action of tumor necrosis factor
40. 2 accompanies cycloheximide- and adenovirus-induced susceptibility to TNF
41. Cell killing and induction of manganous superoxide dismutase by tumor necrosis factor-α is mediated by lipoxygenase metabolites of arachidonic acid
42. Arachidonic acid interaction with the mitochondrial electron transport chain promotes reactive oxygen species generation
43. Regulation of reactive oxygen species-induced apoptosis and necrosis by caspase 3-like proteases
44. Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis
45. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
46. Death receptors: Signaling and modulation
47. Caspases: Intracellular signaling by proteolysis
48. The central executioner of apoptosis: Multiple connections between protease activation and mitochondria in Fas/APO1/CD95- and ceramide-induced apoptosis