-
1
-
-
75149186046
-
Chemotherapy for glioblastoma: Current treatment and future perspectives for cytotoxic and targeted agents
-
Minniti G, Muni R, Lanzetta G, Marchetti P and Enrici RM: Chemotherapy for glioblastoma: current treatment and future perspectives for cytotoxic and targeted agents. Anticancer Res 29: 5171-5184, 2009.
-
(2009)
Anticancer Res
, vol.29
, pp. 5171-5184
-
-
Minniti, G.1
Muni, R.2
Lanzetta, G.3
Marchetti, P.4
Enrici, R.M.5
-
2
-
-
77954718072
-
Current therapeutic paradigms in glioblastoma
-
Quick A, Patel D, Hadziahmetovic M, Chakravarti A and Mehta M: Current therapeutic paradigms in glioblastoma. Rev Recent Clin Trials 5: 14-27, 2010.
-
(2010)
Rev Recent Clin Trials
, vol.5
, pp. 14-27
-
-
Quick, A.1
Patel, D.2
Hadziahmetovic, M.3
Chakravarti, A.4
Mehta, M.5
-
3
-
-
63749125730
-
Translating biology into clinic: The case of glioblastoma
-
Lino M and Merlo A: Translating biology into clinic: the case of glioblastoma. Curr Opin Cell Biol 21: 311-316, 2009.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 311-316
-
-
Lino, M.1
Merlo, A.2
-
4
-
-
4544242478
-
Aromatase, the enzyme responsible for estrogen biosynthesis, is expressed by human and rat glioblastomas
-
Yague JG, Lavaque E, Carretero J, Azcoitia I and Garcia-Segura LM: Aromatase, the enzyme responsible for estrogen biosynthesis, is expressed by human and rat glioblastomas. Neurosci Lett 368: 279-284, 2004.
-
(2004)
Neurosci Lett
, vol.368
, pp. 279-284
-
-
Yague, J.G.1
Lavaque, E.2
Carretero, J.3
Azcoitia, I.4
Garcia-Segura, L.M.5
-
5
-
-
29744467003
-
Estrogen prevents glutamate-induced apoptosis in C6 glioma cells by a receptor-mediated mechanism
-
Sribnick EA, Ray SK and Banik NL: Estrogen prevents glutamate-induced apoptosis in C6 glioma cells by a receptor-mediated mechanism. Neuroscience 137: 197-209, 2006.
-
(2006)
Neuroscience
, vol.137
, pp. 197-209
-
-
Sribnick, E.A.1
Ray, S.K.2
Banik, N.L.3
-
6
-
-
10844232874
-
Agents with selective estrogen receptor (ER) modulator activity induce apoptosis in vitro and in vivo in ER-negative glioma cells
-
Hui AM, Zhang W, Chen W, Xi D, Purow B, Friedman GC and Fine HA: Agents with selective estrogen receptor (ER) modulator activity induce apoptosis in vitro and in vivo in ER-negative glioma cells. Cancer Res 64: 9115-9123, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 9115-9123
-
-
Hui, A.M.1
Zhang, W.2
Chen, W.3
Xi, D.4
Purow, B.5
Friedman, G.C.6
Fine, H.A.7
-
7
-
-
13244286705
-
Activated JNK brings about accelerated apoptosis of Bcl-2-overexpressing C6 glioma cells on treatment with tamoxifen
-
Moodbidri MS and Shirsat NV: Activated JNK brings about accelerated apoptosis of Bcl-2-overexpressing C6 glioma cells on treatment with tamoxifen. J Neurochem 92: 1-9, 2005.
-
(2005)
J Neurochem
, vol.92
, pp. 1-9
-
-
Moodbidri, M.S.1
Shirsat, N.V.2
-
8
-
-
68849130113
-
Activated PKCalpha/ERK1/2 signaling inhibits tamoxifen-induced apoptosis in C6 cells
-
Tian F, Wu H, Li Z, Wang N, Huang J, Li C and Xie F: Activated PKCalpha/ERK1/2 signaling inhibits tamoxifen-induced apoptosis in C6 cells. Cancer Invest 27: 802-808, 2009.
-
(2009)
Cancer Invest
, vol.27
, pp. 802-808
-
-
Tian, F.1
Wu, H.2
Li, Z.3
Wang, N.4
Huang, J.5
Li, C.6
Xie, F.7
-
9
-
-
35349024210
-
JNK pathway regulates estradiol-induced apoptosis in hormone-dependent human breast cancer cells
-
Altiok N, Koyuturk M and Altiok S: JNK pathway regulates estradiol-induced apoptosis in hormone-dependent human breast cancer cells. Breast Cancer Res Treat 105: 247-254, 2007.
-
(2007)
Breast Cancer Res Treat
, vol.105
, pp. 247-254
-
-
Altiok, N.1
Koyuturk, M.2
Altiok, S.3
-
10
-
-
71949090931
-
The two faces of estradiol: Effects on the developing brain
-
McCarthy MM: The two faces of estradiol: effects on the developing brain. Neuroscientist 15: 599-610, 2009.
-
(2009)
Neuroscientist
, vol.15
, pp. 599-610
-
-
McCarthy, M.M.1
-
11
-
-
68549136944
-
Estrogen induces caspase-dependent cell death during hypothalamic development
-
Waters EM and Simerly RB: Estrogen induces caspase-dependent cell death during hypothalamic development. J Neurosci 29: 9714-9718, 2009.
-
(2009)
J Neurosci
, vol.29
, pp. 9714-9718
-
-
Waters, E.M.1
Simerly, R.B.2
-
12
-
-
74049104166
-
Estrogen regulation of apoptosis: How can one hormone stimulate and inhibit?
-
Lewis-Wambi JS and Jordan VC: Estrogen regulation of apoptosis: how can one hormone stimulate and inhibit? Breast Cancer Res 11: 206, 2009.
-
(2009)
Breast Cancer Res
, vol.11
, pp. 206
-
-
Lewis-Wambi, J.S.1
Jordan, V.C.2
-
13
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
-
Bennett BL, Sasaki DT, Murray BW, O'Leary EC, Sakata ST, Xu W, Leisten JC, Motiwala A, Pierce S, Satoh Y, Bhagwat SS, Manning AM and Anderson DW: SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci USA 98: 13681-13686, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13681-13686
-
-
Bennett, B.L.1
Sasaki, D.T.2
Murray, B.W.3
O'Leary, E.C.4
Sakata, S.T.5
Xu, W.6
Leisten, J.C.7
Motiwala, A.8
Pierce, S.9
Satoh, Y.10
Bhagwat, S.S.11
Manning, A.M.12
Anderson, D.W.13
-
14
-
-
45549099394
-
High dose 17 beta-estradiol and the alpha-estrogen agonist PPT trigger apoptosis in human adrenal carcinoma cells but the beta-estrogen agonist DPN does not
-
Prieto LM, Brown JW, Perez-Stable C and Fishman LM: High dose 17 beta-estradiol and the alpha-estrogen agonist PPT trigger apoptosis in human adrenal carcinoma cells but the beta-estrogen agonist DPN does not. Horm Metab Res 40: 311-314, 2008.
-
(2008)
Horm Metab Res
, vol.40
, pp. 311-314
-
-
Prieto, L.M.1
Brown, J.W.2
Perez-Stable, C.3
Fishman, L.M.4
-
15
-
-
33847770799
-
Estrogen action in neuroprotection and brain inflammation
-
Pozzi S, Benedusi V, Maggi A and Vegeto E: Estrogen action in neuroprotection and brain inflammation. Ann N Y Acad Sci 1089: 302-323, 2006.
-
(2006)
Ann N Y Acad Sci
, vol.1089
, pp. 302-323
-
-
Pozzi, S.1
Benedusi, V.2
Maggi, A.3
Vegeto, E.4
-
16
-
-
38749119349
-
Contribution of estrogen receptors alpha and beta to the effects of estradiol in the brain
-
Morissette M, Le Saux M, D'Astous M, Jourdain S, Al Sweidi S, Morin N, Estrada-Camerana E, Mendez P, Garcia-Segura LM and Di Paolo T: Contribution of estrogen receptors alpha and beta to the effects of estradiol in the brain. J Steroid Biochem Mol Biol 108: 327-338, 2008.
-
(2008)
J Steroid Biochem Mol Biol
, vol.108
, pp. 327-338
-
-
Morissette, M.1
le Saux, M.2
D'Astous, M.3
Jourdain, S.4
Al Sweidi, S.5
Morin, N.6
Estrada-Camerana, E.7
Mendez, P.8
Garcia-Segura, L.M.9
di Paolo, T.10
-
17
-
-
39349110405
-
Rapid estrogen signaling in the brain
-
Raz L, Khan MM, Mahesh VB, Vadlamudi RK and Brann DW: Rapid estrogen signaling in the brain. Neurosignals 16: 140-153, 2008.
-
(2008)
Neurosignals
, vol.16
, pp. 140-153
-
-
Raz, L.1
Khan, M.M.2
Mahesh, V.B.3
Vadlamudi, R.K.4
Brann, D.W.5
-
18
-
-
72149133431
-
Plasma membrane estrogen receptors
-
Levin ER: Plasma membrane estrogen receptors. Trends Endocrinol Metab 20: 477-482, 2009.
-
(2009)
Trends Endocrinol Metab
, vol.20
, pp. 477-482
-
-
Levin, E.R.1
-
19
-
-
23944466208
-
Context-specific inhibition of JNKs: Overcoming the dilemma of protection and damage
-
Waetzig V and Herdegen T: Context-specific inhibition of JNKs: overcoming the dilemma of protection and damage. Trends Pharmacol Sci 26: 455-461, 2005.
-
(2005)
Trends Pharmacol Sci
, vol.26
, pp. 455-461
-
-
Waetzig, V.1
Herdegen, T.2
-
20
-
-
50349092257
-
All JNKs can kill, but nuclear localization is critical for neuronal death
-
Björkblom B, Vainio JC, Hongisto V, Herdegen T, Courtney MJ and Coffey ET: All JNKs can kill, but nuclear localization is critical for neuronal death. J Biol Chem 283: 19704-19713, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 19704-19713
-
-
Björkblom, B.1
Vainio, J.C.2
Hongisto, V.3
Herdegen, T.4
Courtney, M.J.5
Coffey, E.T.6
-
21
-
-
33947236886
-
Docetaxel-induced apoptosis of human melanoma is mediated by activation of c-Jun NH2-terminal kinase and inhibited by the mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway
-
Mhaidat NM, Zhang XD, Jiang CC and Hersey P: Docetaxel-induced apoptosis of human melanoma is mediated by activation of c-Jun NH2-terminal kinase and inhibited by the mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway. Clin Cancer Res 13: 1308-1314, 2007.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1308-1314
-
-
Mhaidat, N.M.1
Zhang, X.D.2
Jiang, C.C.3
Hersey, P.4
-
22
-
-
41549126681
-
Distinct signaling pathways of microtubule inhibitors-vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively
-
Kolomeichuk SN, Terrano DT, Lyle CS, Sabapathy K and Chambers TC: Distinct signaling pathways of microtubule inhibitors-vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively. FEBS J 275: 1889-1899, 2008.
-
(2008)
FEBS J
, vol.275
, pp. 1889-1899
-
-
Kolomeichuk, S.N.1
Terrano, D.T.2
Lyle, C.S.3
Sabapathy, K.4
Chambers, T.C.5
-
23
-
-
54049101586
-
c-Jun N-terminal kinase activation failure is a new mechanism of anthracycline resistance in acute myeloid leukemia
-
Lagadinou ED, Ziros PG, Tsopra OA, Dimas K, Kokkinou D, Thanopoulou E, Karakantza M, Pantazis P, Spyridonidis A and Zoumbos NC: c-Jun N-terminal kinase activation failure is a new mechanism of anthracycline resistance in acute myeloid leukemia. Leukemia 22: 1899-1908, 2008.
-
(2008)
Leukemia
, vol.22
, pp. 1899-1908
-
-
Lagadinou, E.D.1
Ziros, P.G.2
Tsopra, O.A.3
Dimas, K.4
Kokkinou, D.5
Thanopoulou, E.6
Karakantza, M.7
Pantazis, P.8
Spyridonidis, A.9
Zoumbos, N.C.10
-
24
-
-
70450285202
-
AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis
-
Zerp SF, Stoter R, Kuipers G, Yang D, Lippman ME, van Blitterswijk WJ, Bartelink H, Rooswinkel R, Lafleur V and Verheij M: AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis. Radiat Oncol 4: 47, 2009.
-
(2009)
Radiat Oncol
, vol.4
, pp. 47
-
-
Zerp, S.F.1
Stoter, R.2
Kuipers, G.3
Yang, D.4
Lippman, M.E.5
van Blitterswijk, W.J.6
Bartelink, H.7
Rooswinkel, R.8
Lafleur, V.9
Verheij, M.10
-
25
-
-
77955660663
-
Diverse somatic mutation patterns and pathway alterations in human cancers
-
Kan Z, Jaiswal BS, Stinson J, Janakiraman V, Bhatt D, Stern HM, Yue P, Haverty PM, Bourgon R, Zheng J, Moorhead M, Chaudhuri S, Tomsho LP, Peters BA, Pujara K, Cordes S, Davis DP, Carlton VE, Yuan W, Li L, Wang W, Eigenbrot C, Kaminker JS, Eberhard DA, Waring P, Schuster SC, Modrusan Z, Zhang Z, Stokoe D, de Sauvage FJ, Faham M and Seshagiri S: Diverse somatic mutation patterns and pathway alterations in human cancers. Nature 466: 869-73, 2010.
-
(2010)
Nature
, vol.466
, pp. 869-873
-
-
Kan, Z.1
Jaiswal, B.S.2
Stinson, J.3
Janakiraman, V.4
Bhatt, D.5
Stern, H.M.6
Yue, P.7
Haverty, P.M.8
Bourgon, R.9
Zheng, J.10
Moorhead, M.11
Chaudhuri, S.12
Tomsho, L.P.13
Peters, B.A.14
Pujara, K.15
Cordes, S.16
Davis, D.P.17
Carlton, V.E.18
Yuan, W.19
Li, L.20
Wang, W.21
Eigenbrot, C.22
Kaminker, J.S.23
Eberhard, D.A.24
Waring, P.25
Schuster, S.C.26
Modrusan, Z.27
Zhang, Z.28
Stokoe, D.29
de Sauvage, F.J.30
Faham, M.31
Seshagiri, S.32
more..
-
26
-
-
79952147408
-
Apoptosis induced by cytoskeletal disruption requires distinct domains of MEKK1
-
Tricker E, Arvand A, Kwan R, Chen GY, Gallagher E and Cheng G. Apoptosis induced by cytoskeletal disruption requires distinct domains of MEKK1. PLoS One 6: e17310, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Tricker, E.1
Arvand, A.2
Kwan, R.3
Chen, G.Y.4
Gallagher, E.5
Cheng, G.6
|