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Volumn 15, Issue 6, 2009, Pages 599-610

The two faces of estradiol: Effects on the developing brain

Author keywords

Hypothalamus; Neuroprotection; Preoptic area; Prostaglandins; Sex behavior; Sex differences

Indexed keywords

4 AMINOBUTYRIC ACID; ESTRADIOL; GLUTAMIC ACID;

EID: 71949090931     PISSN: 10738584     EISSN: 10894098     Source Type: Journal    
DOI: 10.1177/1073858409340924     Document Type: Review
Times cited : (98)

References (48)
  • 1
    • 2442499103 scopus 로고    scopus 로고
    • Brain estradiol content in newborn rats: Sex differences, regional heterogeneity, and possible de novo synthesis by the female telencephalon
    • Amateau SK, Alt JJ, Stamps CL, McCarthy MM. 2004. Brain estradiol content in newborn rats: sex differences, regional heterogeneity, and possible de novo synthesis by the female telencephalon. Endocrinology 145:2906-2917
    • (2004) Endocrinology , vol.145 , pp. 2906-2917
    • Amateau, S.K.1    Alt, J.J.2    Stamps, C.L.3    McCarthy, M.M.4
  • 2
    • 0036813151 scopus 로고    scopus 로고
    • A novel mechanism of dendritic spine plasticity involving estradiol induction of prostglandin-E2
    • Amateau SK, McCarthy MM. 2002a. A novel mechanism of dendritic spine plasticity involving estradiol induction of prostglandin-E2. J. Neurosci 22:8586-8596
    • (2002) J. Neurosci , vol.22 , pp. 8586-8596
    • Amateau, S.K.1    McCarthy, M.M.2
  • 3
    • 0036853622 scopus 로고    scopus 로고
    • Sexual differentiation of astrocyte morphology in the developing rat preoptic area
    • DOI 10.1046/j.1365-2826.2002.00858.x
    • Amateau SK, McCarthy MM. 2002b. Sexual differentiation of astrocyte morphology in the developing rat preoptic area. J Neuroendocrinol 14:904-910 (Pubitemid 35378708)
    • (2002) Journal of Neuroendocrinology , vol.14 , Issue.11 , pp. 904-910
    • Amateur, S.K.1    McCarthy, M.M.2
  • 4
    • 2542429265 scopus 로고    scopus 로고
    • Induction of PGE(2) by estradiol mediates developmental masculinization of sex behavior
    • Amateau SK, McCarthy MM. 2004. Induction of PGE(2) by estradiol mediates developmental masculinization of sex behavior. Nat Neurosci 7:643-650
    • (2004) Nat Neurosci , vol.7 , pp. 643-650
    • Amateau, S.K.1    McCarthy, M.M.2
  • 5
    • 0029782444 scopus 로고    scopus 로고
    • Estrogen and apoptosis in the developing sexually dimorphic preoptic area in female rats
    • DOI 10.1016/S0168-0102(96)01070-X
    • Arai Y, Sekine Y, Murakami S. 1996. Estrogen and apoptosis in the developing sexually dimorphic preoptic area in female rats. Neurosci Res 25:403-407 (Pubitemid 26270795)
    • (1996) Neuroscience Research , vol.25 , Issue.4 , pp. 403-407
    • Arai, Y.1    Sekine, Y.2    Murakami, S.3
  • 6
    • 31544483631 scopus 로고    scopus 로고
    • Alpha-fetoprotein protects the developing female mouse brain from masculinization and defeminization by estrogens
    • Bakker J, De Mees C, Douhard Q, Balthazart J, Gabant P, Szpirer J, and others. 2006. Alpha-fetoprotein protects the developing female mouse brain from masculinization and defeminization by estrogens. Nat Neurosci 9:220-226
    • (2006) Nat Neurosci , vol.9 , pp. 220-226
    • Bakker, J.1    De Mees, C.2    Douhard, Q.3    Balthazart, J.4    Gabant, P.5    Szpirer, J.6
  • 7
    • 0032102369 scopus 로고    scopus 로고
    • New insights into the regulation and function of brain estrogen synthase (aromatase)
    • DOI 10.1016/S0166-2236(97)01221-6
    • Balthazart J, Ball GF. 1998. New insights into the regulation and function of brain estrogen synthase (aromatase). Trends Neurosci 21:243-249 (Pubitemid 28239981)
    • (1998) Trends in Neurosciences , vol.21 , Issue.6 , pp. 243-249
    • Balthazart, J.1    Ball, G.F.2
  • 8
    • 33646134623 scopus 로고    scopus 로고
    • Is brain estradiol a hormone or a neurotransmitter?
    • Balthazart J, Ball GF. 2006. Is brain estradiol a hormone or a neurotransmitter? Trends Neurosci 29:241-249
    • (2006) Trends Neurosci , vol.29 , pp. 241-249
    • Balthazart, J.1    Ball, G.F.2
  • 9
    • 33644512766 scopus 로고    scopus 로고
    • Rapid changes in production and behavioral action of estrogens
    • DOI 10.1016/j.neuroscience.2005.06.016, PII S0306452205006524, Neuroactive Steroids: Old Players in a New Game
    • Balthazart J, Cornil CA, Taziaux M, Charlier TD, Baillien M, Ball GF. 2006. Rapid changes in production and behavioral action of estrogens. Neuroscience 138:783-791 (Pubitemid 43306817)
    • (2006) Neuroscience , vol.138 , Issue.3 , pp. 783-791
    • Balthazart, J.1    Cornil, C.A.2    Taziaux, M.3    Charlier, T.D.4    Baillien, M.5    Ball, G.F.6
  • 10
    • 0034129679 scopus 로고    scopus 로고
    • Steroid hormone receptors: An update
    • Beato M, Klug J. 2000. Steroid hormone receptors: an update. Hum Reprod Update 6:225-236
    • (2000) Hum Reprod Update , vol.6 , pp. 225-236
    • Beato, M.1    Klug, J.2
  • 11
    • 53049099496 scopus 로고    scopus 로고
    • Steroids, sex and the cerebellar cortex: Implications for human disease
    • Dean SL, McCarthy MM. 2008. Steroids, sex and the cerebellar cortex: implications for human disease. Cerebellum 7:38-47.
    • (2008) Cerebellum , vol.7 , pp. 38-47
    • Dean, S.L.1    McCarthy, M.M.2
  • 12
    • 33644537379 scopus 로고    scopus 로고
    • Cell death and sexual differentiation of the nervous system
    • DOI 10.1016/j.neuroscience.2005.07.006, PII S0306452205007475, Neuroactive Steroids: Old Players in a New Game
    • Forger NG. 2006. Cell death and sexual differentiation of the nervous system. Neuroscience 138:929-938 (Pubitemid 43306833)
    • (2006) Neuroscience , vol.138 , Issue.3 , pp. 929-938
    • Forger, N.G.1
  • 13
    • 63549131345 scopus 로고    scopus 로고
    • Control of cell number in the sexually dimorphic brain and spinal cord
    • Forger NG. 2009. Control of cell number in the sexually dimorphic brain and spinal cord. J Neuroendocrinol 21:393-399
    • (2009) J Neuroendocrinol , vol.21 , pp. 393-399
    • Forger, N.G.1
  • 15
    • 0035907025 scopus 로고    scopus 로고
    • GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition
    • DOI 10.1016/S0092-8674(01)00341-5
    • Ganguly K, Schinder AF, Wong ST, Poo M. 2001. GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition. Cell 105:521-532 (Pubitemid 32520857)
    • (2001) Cell , vol.105 , Issue.4 , pp. 521-532
    • Ganguly, K.1    Schinder, A.F.2    Wong, S.T.3    Poo, M.-M.4
  • 17
    • 33845665863 scopus 로고    scopus 로고
    • ++ from intracellular stores and is prevented by estradiol
    • DOI 10.1111/j.1460-9568.2006.05189.x
    • Hilton GD, Nunez JL, Bambrick L, Thompson SM, McCarthy MM. 2006. Glutamate-mediated excitotoxicity in neonatal hippocampal neurons is mediated by mGluR-induced release of Ca++ from intracellular stores and is prevented by estradiol. Eur J Neurosci 24:3008-3016 (Pubitemid 44952633)
    • (2006) European Journal of Neuroscience , vol.24 , Issue.11 , pp. 3008-3016
    • Hilton, G.D.1    Nunez, J.L.2    Bambrick, L.3    Thompson, S.M.4    McCarthy, M.M.5
  • 18
    • 9144237423 scopus 로고    scopus 로고
    • Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017alpha and P450 aromatase localized in neurons
    • Hojo Y, Hattori TA, Enami T, Furukawa A, Suzuki K, Ishii HT, and others. 2004. Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017alpha and P450 aromatase localized in neurons. Proc Natl Acad Sci U S A 101:865-870
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 865-870
    • Hojo, Y.1    Hattori, T.A.2    Enami, T.3    Furukawa, A.4    Suzuki, K.5    Ishii, H.T.6
  • 19
    • 62749136210 scopus 로고    scopus 로고
    • Membrane estrogen receptor-alpha interacts with metabotropic glutamate receptor type 1a to mobilize intracellular calcium in hypothalamic astrocytes
    • Kuo J, Hariri OR, Bondar G, Ogi J, Micevych P. 2009. Membrane estrogen receptor-alpha interacts with metabotropic glutamate receptor type 1a to mobilize intracellular calcium in hypothalamic astrocytes. Endocrinology 150:1369-1376
    • (2009) Endocrinology , vol.150 , pp. 1369-1376
    • Kuo, J.1    Hariri, O.R.2    Bondar, G.3    Ogi, J.4    Micevych, P.5
  • 20
    • 38349049457 scopus 로고    scopus 로고
    • Estradiol and the developing brain
    • McCarthy MM. 2008. Estradiol and the developing brain. Physiol Rev 88:91-124.
    • (2008) Physiol Rev , vol.88 , pp. 91-124
    • McCarthy, M.M.1
  • 21
    • 23744481466 scopus 로고    scopus 로고
    • When is a sex difference not a sex difference?
    • McCarthy MM, Konkle AT. 2005. When is a sex difference not a sex difference? Front Neuroendocrinol 26:85-102.
    • (2005) Front Neuroendocrinol , vol.26 , pp. 85-102
    • McCarthy, M.M.1    Konkle, A.T.2
  • 22
    • 0033557656 scopus 로고    scopus 로고
    • Gonadal steroids promote glial differentiation and alter neuronal morphology in the developing hypothalamus in a regionally specific manner
    • Mong JA, Glaser E, McCarthy MM. 1999. Gonadal steroids promote glial differentiation and alter neuronal morphology in the developing hypothalamus in a regionally specific manner. J Neurosci 19:1464-1472 (Pubitemid 29088927)
    • (1999) Journal of Neuroscience , vol.19 , Issue.4 , pp. 1464-1472
    • Mong, J.A.1    Glaser, E.2    McCarthy, M.M.3
  • 23
    • 0037115045 scopus 로고    scopus 로고
    • Ontogeny of sexually dimorphic astrocytes in the neonatal rat arcuate
    • Mong JA, McCarthy MM. 2002. Ontogeny of sexually dimorphic astrocytes in the neonatal rat arcuate. Dev Brain Res 139:151-158
    • (2002) Dev Brain Res , vol.139 , pp. 151-158
    • Mong, J.A.1    McCarthy, M.M.2
  • 24
    • 0036150353 scopus 로고    scopus 로고
    • GABA mediates steroid-induced astrocyte differentiation in the neonatal rat hypothalamus
    • Mong JA, Nunez JL, McCarthy MM. 2002. GABA mediates steroid-induced astrocyte differentiation in the neonatal rat hypothalamus. J Neuroendocrinol 14:1-16.
    • (2002) J Neuroendocrinol , vol.14 , pp. 1-16
    • Mong, J.A.1    Nunez, J.L.2    McCarthy, M.M.3
  • 25
    • 13844301056 scopus 로고    scopus 로고
    • Sexual differentiation of the vertebrate nervous system
    • DOI 10.1038/nn1325
    • Morris JA, Jordan CL, Breedlove SM. 2004. Sexual differentiation of the vertebrate nervous system. Nat Neurosci 7:1034-1039 (Pubitemid 41184441)
    • (2004) Nature Neuroscience , vol.7 , Issue.10 , pp. 1034-1039
    • Morris, J.A.1    Jordan, C.L.2    Breedlove, S.M.3
  • 26
    • 36048934367 scopus 로고    scopus 로고
    • 17Beta-Estradiol protects the neonatal brain from hypoxia-ischemia
    • DOI 10.1016/j.expneurol.2007.08.020, PII S0014488607003317
    • Nunez J, Yang Z, Jian Y, Grandys T, Mark I, Levison SW. 2007. 17Beta-estradiol protects the neontal brain from hypoxia-ischemia. Exp Neurol 208:269-276 (Pubitemid 350101505)
    • (2007) Experimental Neurology , vol.208 , Issue.2 , pp. 269-276
    • Nunez, J.1    Yang, Z.2    Jiang, Y.3    Grandys, T.4    Mark, I.5    Levison, S.W.6
  • 27
    • 57349115390 scopus 로고    scopus 로고
    • Impact of estradiol on GABA- And glutamatemediated calcium responses of fetal baboon (papio anubis) hippocampal and cortical neurons
    • Nunez JL, Aberdeen GW, Albrecht ED, McCarthy MM. 2008. Impact of estradiol on GABA- and glutamatemediated calcium responses of fetal baboon (papio anubis) hippocampal and cortical neurons. Endocrinology 149:6433-6443
    • (2008) Endocrinology , vol.149 , pp. 6433-6443
    • Nunez, J.L.1    Aberdeen, G.W.2    Albrecht, E.D.3    McCarthy, M.M.4
  • 28
    • 21844464878 scopus 로고    scopus 로고
    • Prolongation and enhancement of gamma-aminobutyric acid receptor mediated excitation by chronic treatment with estradiol in developing rat hippocampal neurons
    • Nunez JL, Bambrick LL, Krueger BK, McCarthy MM. 2005. Prolongation and enhancement of gamma-aminobutyric acid receptor mediated excitation by chronic treatment with estradiol in developing rat hippocampal neurons. Eur J Neurosci 21:3251-3261
    • (2005) Eur J Neurosci , vol.21 , pp. 3251-3261
    • Nunez, J.L.1    Bambrick, L.L.2    Krueger, B.K.3    McCarthy, M.M.4
  • 29
    • 0037900205 scopus 로고    scopus 로고
    • Estradiol exacerbates hippocampal damage in a model of preterm infant brain injury
    • DOI 10.1210/en.2002-220840
    • Nunez JL, McCarthy MM. 2003. Estradiol exacerbates hippocampal damage in a model of preterm brain injury. Endocrinology 144:2350-2359 (Pubitemid 36629886)
    • (2003) Endocrinology , vol.144 , Issue.6 , pp. 2350-2359
    • Nunez, J.L.1    McCarthy, M.M.2
  • 30
    • 58149471762 scopus 로고    scopus 로고
    • Resting intracellular calcium concentration, depolarizing GABA and possible role of local estradiol synthesis in the developing male and female hippocampus
    • Nunez JL, McCarthy MM. 2008. Resting intracellular calcium concentration, depolarizing GABA and possible role of local estradiol synthesis in the developing male and female hippocampus. Neuroscience 158:623-634
    • (2008) Neuroscience , vol.158 , pp. 623-634
    • Nunez, J.L.1    McCarthy, M.M.2
  • 31
    • 0037470587 scopus 로고    scopus 로고
    • Excitatory GABA-induced pCREB in developing brain is mediated by L-type Ca+2 channels and dependent on age, sex and brain region
    • Perrot-Sinal TS, Auger AP, McCarthy MM. 2003. Excitatory GABA-induced pCREB in developing brain is mediated by L-type Ca+2 channels and dependent on age, sex and brain region. Neuroscience 116: 995-1003.
    • (2003) Neuroscience , vol.116 , pp. 995-1003
    • Perrot-Sinal, T.S.1    Auger, A.P.2    McCarthy, M.M.3
  • 32
    • 0035015760 scopus 로고    scopus 로고
    • Estradiol enhances excitatory gamma-aminobutyric acid-mediated calcium signaling in neonatal hypothalamic neurons
    • Perrot-Sinal TS, Davis AM, Gregerson KA, Kao JPY, McCarthy MM. 2001. Estradiol enhances excitatory gamma-aminobutyric acid-mediated calcium signaling in neonatal hypothalamic neurons. Endocrinology 143:2238-2243
    • (2001) Endocrinology , vol.143 , pp. 2238-2243
    • Perrot-Sinal, T.S.1    Davis, A.M.2    Gregerson, K.A.3    Kao, J.P.Y.4    McCarthy, M.M.5
  • 33
    • 0015820726 scopus 로고
    • Atlas of estradiol-concentrating cells in the central nervous system of the female rat
    • Pfaff DW, Keiner M. 1973. Atlas of estradiol-concentrating cells in the central nervous system of the female rat. J Comp Neurol 151:121-158
    • (1973) J Comp Neurol , vol.151 , pp. 121-158
    • Pfaff, D.W.1    Keiner, M.2
  • 34
    • 0037275211 scopus 로고    scopus 로고
    • Para/autocrine regulation of estrogen receptors in hippocampal neurons
    • DOI 10.1002/hipo.10075
    • Prange-Kiel J, Wehrenberg U, Jarry H, Rune GM. 2003. Para/autocrine regulation of estrogen receptors in hippocampal neurons. Hippocampus 13:226-234 (Pubitemid 36503535)
    • (2003) Hippocampus , vol.13 , Issue.2 , pp. 226-234
    • Prange-Kiel, J.1    Wehrenberg, U.2    Jarry, H.3    Rune, G.M.4
  • 36
    • 0033590541 scopus 로고    scopus 로고
    • The K+/Cl- Co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation
    • see comments
    • Rivera C, Voipio J, Payne JA, Ruusuvuori E, Lahtinen H, Lamsa K, and others. 1999. The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation [see comments]. Nature 397:251-255
    • (1999) Nature , vol.397 , pp. 251-255
    • Rivera, C.1    Voipio, J.2    Payne, J.A.3    Ruusuvuori, E.4    Lahtinen, H.5    Lamsa, K.6
  • 37
    • 0037008453 scopus 로고    scopus 로고
    • Estrogen up-regulates estrogen receptor alpha and synaptophysin in slice cultures of rat hippocampus
    • DOI 10.1016/S0306-4522(02)00152-5, PII S0306452202001525
    • Rune GM, Wehrenberg U, Prange-Kiel J, Zhou L, Adelmann G, Frotscher M. 2002. Estrogen up-regulates estrogen receptor alpha and synaptophysin in slice cultures of rat hippocampus. Neuroscience 113:167-175 (Pubitemid 34786022)
    • (2002) Neuroscience , vol.113 , Issue.1 , pp. 167-175
    • Rune, G.M.1    Wehrenberg, U.2    Prange-Kiel, J.3    Zhou, L.4    Adelmann, G.5    Frotscher, M.6
  • 38
    • 43449086113 scopus 로고    scopus 로고
    • Estradiol induces hypothalamic dendritic spines by enhancing glutamate release: A mechanism for organizational sex differences
    • Schwarz JM, Liang S-L, Thompson SM, McCarthy MM. 2008. Estradiol induces hypothalamic dendritic spines by enhancing glutamate release: a mechanism for organizational sex differences. Neuron 58:584-598
    • (2008) Neuron , vol.58 , pp. 584-598
    • Schwarz, J.M.1    Liang, S.-L.2    Thompson, S.M.3    McCarthy, M.M.4
  • 39
    • 43549120758 scopus 로고    scopus 로고
    • Steroid-induced sexual differentiation of the brain: Multiple pathways, one goal
    • Schwarz JM, McCarthy MM. 2008. Steroid-induced sexual differentiation of the brain: multiple pathways, one goal. J Neurochem 105:1561-1572
    • (2008) J Neurochem , vol.105 , pp. 1561-1572
    • Schwarz, J.M.1    McCarthy, M.M.2
  • 40
    • 0036308456 scopus 로고    scopus 로고
    • Wired for reproduction: Organization and development of sexually dimorphic circuits in the mammalian forebrain
    • Simerly RB. 2002. Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain. Annu Rev Neurosci 25:507-536
    • (2002) Annu Rev Neurosci , vol.25 , pp. 507-536
    • Simerly, R.B.1
  • 41
    • 34347268809 scopus 로고    scopus 로고
    • Focal adhesion kinase and paxillin: Novel regulators of brain sexual differentiation?
    • Speert DB, Konkle AT, Zup SL, Schwarz JM, Shiroor C, Taylor ME, and others. 2007. Focal adhesion kinase and paxillin: novel regulators of brain sexual differentiation? Endocrinology 148:3391-3401
    • (2007) Endocrinology , vol.148 , pp. 3391-3401
    • Speert, D.B.1    Konkle, A.T.2    Zup, S.L.3    Schwarz, J.M.4    Shiroor, C.5    Taylor, M.E.6
  • 42
    • 0030222772 scopus 로고    scopus 로고
    • Alteration of GABA(A) receptor function following gene transfer of the CLC-2 chloride channel
    • DOI 10.1016/S0896-6273(00)80186-5
    • Staley K, Smith R, Schaack J, Wilcox C, Jentsch TJ. 1996. Alteration of GABA-A receptor function following gene transfer of the CLC-2 chloride channel. Neuron 17: 543-551 (Pubitemid 26322225)
    • (1996) Neuron , vol.17 , Issue.3 , pp. 543-551
    • Staley, K.1    Smith, R.2    Schaack, J.3    Wilcox, C.4    Jentsch, T.J.5
  • 43
    • 27844556866 scopus 로고    scopus 로고
    • Prostaglandin-E2: A point of divergence in estradiol-mediated sexual differentiation
    • Todd BJ, Schwarz JM, McCarthy MM. 2005. Prostaglandin-E2: a point of divergence in estradiol-mediated sexual differentiation. Horm Behav 48:512-521
    • (2005) Horm Behav , vol.48 , pp. 512-521
    • Todd, B.J.1    Schwarz, J.M.2    McCarthy, M.M.3
  • 44
    • 1442323686 scopus 로고    scopus 로고
    • Minireview: A plethora of estrogen receptors in the brain: where will it end?
    • Toran-Allerand CD. 2004. Minireview: a plethora of estrogen receptors in the brain: where will it end? Endocrinology 145:1069-1074
    • (2004) Endocrinology , vol.145 , pp. 1069-1074
    • Toran-Allerand, C.D.1
  • 45
    • 0036813660 scopus 로고    scopus 로고
    • ER-X: A novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury
    • Toran-Allerand CD, Guan X, MacLusky NJ, Horvath TL, Diano S, Singh M, and others. 2002. ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury. J Neurosci 22:8391-8401
    • (2002) J Neurosci , vol.22 , pp. 8391-8401
    • Toran-Allerand, C.D.1    Guan, X.2    MacLusky, N.J.3    Horvath, T.L.4    Diano, S.5    Singh, M.6
  • 46
    • 0038363692 scopus 로고    scopus 로고
    • Estrogens: Protective or risk factors in brain function?
    • Wise PM. 2003. Estrogens: protective or risk factors in brain function? Prog Neurobiol 69:181-191
    • (2003) Prog Neurobiol , vol.69 , pp. 181-191
    • Wise, P.M.1
  • 47
    • 53049084719 scopus 로고    scopus 로고
    • Identification of prostaglandin E2 receptors mediating perinatal masculinization of adult sex behavior and neuroanatomical correlates
    • Wright CL, Burks SR, McCarthy MM. 2008. Identification of prostaglandin E2 receptors mediating perinatal masculinization of adult sex behavior and neuroanatomical correlates. Dev Neurobiol 68:1406-1419
    • (2008) Dev Neurobiol , vol.68 , pp. 1406-1419
    • Wright, C.L.1    Burks, S.R.2    McCarthy, M.M.3
  • 48
    • 40549118239 scopus 로고    scopus 로고
    • Impact of sex and hormones on new cells in the developing rat hippocampus: A novel source of sex dimorphism?
    • Zhang J-M, Konkle ATM, Zup SL, McCarthy MM. 2008. Impact of sex and hormones on new cells in the developing rat hippocampus: a novel source of sex dimorphism? Eur J Neurosci 27:791-800.
    • (2008) Eur J Neurosci , vol.27 , pp. 791-800
    • Zhang, J.-M.1    Konkle, A.T.M.2    Zup, S.L.3    McCarthy, M.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.