δ-aminolevulinic acid-induced protoporphyrin IX concentration correlates with histopathologic markers of malignancy in human gliomas: The need for quantitative fluorescence-guided resection to identify regions of increasing malignancy

Neuro-Oncology

Volumn 13, Issue 8, 2011, Pages 846-856

  Valdé S, Pablo A ^a,b   Kim, Anthony ^c   Brantsch, Marco ^c   Niu, Carolyn ^c   Moses, Ziev B ^a   Tosteson, Tor D ^d,e   Wilson, Brian C ^c   Paulsen, Keith D ^a,b,e   Roberts, David W ^a,b,e   Harris, Brent T ^a,e,f  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b DARTMOUTH COLLEGE   (United States)

^c PRINCESS MARGARET HOSPITAL   (Canada)

^d DARTMOUTH INSTITUTE FOR HEALTH POLICY AND CLINICAL PRACTICE   (United States)

^e DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^f GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

aminolevulinic acid; Fluorescence guided resection; Malignant glioma; Proliferation index; Protoporphyrin IX

Indexed keywords

AMINOLEVULINIC ACID; BRAIN PROTEIN; KI 67 ANTIGEN; PROTOPORPHYRIN;

ADULT; AGED; ARTICLE; BRAIN LEVEL; CANCER GRADING; CANCER SURGERY; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; FLUORESCENCE; FLUORESCENCE GUIDED RESECTION; FLUORESCENCE IMAGING; FLUOROMETRY; GLIOMA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; QUANTITATIVE ANALYSIS; TUMOR BIOPSY;

ADULT; AGED; AMINOLEVULINIC ACID; BIOLOGICAL MARKERS; BRAIN NEOPLASMS; DIAGNOSTIC IMAGING; FEMALE; FLUORESCENCE; FLUOROMETRY; GLIOMA; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; MONITORING, INTRAOPERATIVE; PHOTOSENSITIZING AGENTS; PROTOPORPHYRINS; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 80052732848     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nor086     Document Type: Article

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