Factors affecting aminolaevulinic acid-induced generation of protoporphyrin IX

British Journal of Cancer

Volumn 76, Issue 6, 1997, Pages 705-712

  Wyld, L ^a   Burn, J L ^a   Reed, M W R ^a   Brown, N J ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Aminolaevulinic acid; Endothelial cells; Microcirculation; Photodynamic therapy; Protoporphyrin IX

Indexed keywords

AMINOLEVULINIC ACID; PHOTOSENSITIZING AGENT; PROTOPORPHYRIN;

ARTICLE; CELL PROLIFERATION; CYTOTOXICITY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MICROCIRCULATION; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; TUMOR VASCULARIZATION; VASCULAR SMOOTH MUSCLE;

EID: 0030817496     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1997.450     Document Type: Article

References (34)

1. Bedwell J, Macrobert AJ, Phillips D and Bown SG (1992) Fluorescence distribution and photodynamic effect of ALA-induced PpIX in the DMH rat colonic tumour model. Br J Cancer 65: 818-824
2. Bermudez-Moretti M, Correa-Garcia C, Stell E, Ramos E and Battle AM (1993) Delta-aminolaevulinic acid transport in Saccharomyces cerevisiae. Int J Biochem 25: 1917-1924
3. Denekamp J (1982) Endothelial cell proliferation as a novel approach to targeting tumour therapy. Br J Cancer 45: 136-139
4. El-Sharabasy MMH, El-Waseef AM, Hafez MM and Salim SA (1992) Porphyrin metabolism in some malignant diseases. Br J Cancer 65: 413-416
5. Falk JE, Porra RJ, Brown A, Moss F and Larminie HE (1959) Effect of oxygen tension on haem and porphyrin biosynthesis. Nature 184: 1217-1219
6. Fukuda H, Batlle AMC and Riley PA (1993) Kinetics of porphyrin accumulation in cultured epithelial cells exposed to ALA. Int J Biochem 25: 1407-1410
7. Gilissen MJ, Van de Merbel-de Wit LEA, Star WM, Koster JF and Sluiter W (1993) Effect of photodynamic therapy on the endothelium-dependent relaxation of isolated rat aortas. Cancer Res 53: 2548-2552
8. Hanania J and Malik Z (1992) The effect of EDTA and serum on endogenous porphyrin accumulation and photodynamic sensitisation of human K562 leukaemic cells. Cancer Lett 65: 127-131
9. Hewett PW and Murray JC (1993) Human microvessel endothelial cells: isolation. culture and characterisation. In Vitro Cell Dev Biol 29A: 823-830
10. Iinuma S, Farshi SS, Ortel B and Hasan T (1994) A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin. Br J Cancer 70: 21-28
11. Jacob G, Curzer MN and Fuller BJ (1985) An assessment of human cell viability after in vitro freezing. Crobiology 22: 417-426
12. Jaffe EA, Nachman RL, Becker CG and Minick CR (1973) Culture of human endothelial cells derived from umbilical veins. J Clin Invest 52: 2745-2756
13. Leveckis J, Brown NJ and Reed MWR (1995) The effect of aminolaevulinic acid-induced, protoporphyrin IX mediated photodynamic therapy on the cremaster muscle microcirculation in vivo. Br J Cancer 72: 1113-1119
14. Lim HW, Behar S and He D (1994) Effect of porphyrin and irradiation on heme biosynthetic pathway in endothelial cells. Photodermatol Photoimmunol Photomed 10: 17-21
15. Lin F and Girotti AW (1995) Stimulatory and inhibitory effects of iron on photodynamic inactivation of leukaemia cells. Photochem Photobiol 62: 528-534
16. Linberg RA, Slaaf DW, Lentsch AB and Miller FN (1994) Involvement of nitric oxide and cyclooxygenase products in photoactivation-induced microvascular occlusion. Microvasc Res 47: 203-221
17. Loh CS, Macrobert AJ, Bedwell J, Regula J, Krasner N and Bown SG (1993) Oral versus intravenous administration of 5-aminolaevulinic acid for photodynamic therapy. Br J Cancer 68: 41-51
18. Lowry OH, Rosebrough NJ, Farr AL and Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275
19. Martin DW (1983) Porphyrins. In Harper's Review of Biochemistry, Martin DW, Mayes PA, Rodwell VW (eds), pp. 317-333. Lange Medical Publications: Los Altos, CA
20. Mitchell JB, McPherson S, Degraff W, Gamson J, Zabell A and Russo A (1985) Oxygen dependence of hematoporphyrin derivative-induced photoinactivation of chinese hamster cells. Cancer Res 45: 2008-2011
21. Moore EC and Reichard P (1964) Enzymatic synthesis of deoxyribonucleotides. J Biol Chem 239: 3453-3456
22. Reed MWR, Weiman TJ, Schuschke DA, Tseng MT and Miller FN (1989a) A comparison of the effect of photodynamic therapy on normal and tumour blood vessels in the rat microcirculation. Radiat Res 119: 542-552
23. Reed MWR, Weiman TJ, Doak KW, Pietsch CG and Schuschke DA (1989b) The microvascular effects of photodynamic therapy: evidence for a possible role of cyclooxygenase products. Photochem Photobiol 50: 419-423
24. Rebeiz N, Rebeiz CC, Arkins S, Kelley KW and Rebeiz CA (1992) Photodestruction of tumour cells by induction of endogenous accumulation of protoporphyrin IX: enhancement by 1,10-phenanthroline. Photochem Photobiol 55: 431-135
25. Rittenhouse-Diakun K, Van Leengoed H, Morgan J, Hryhorenko E, Paszkiewicz G, Whitaker JE and Oseroff AR (1995) The role of transferin receptor (CD71) in photodynamic therapy of activated and malignant lymphocytes using the heme precursor δ-aminolaevulinic acid (ALA). Photochem Photobiol 61: 523-528
26. Roberts DJH, Cairnduff F, Driver I, Dixon B and Brown SB (1994) Tumour vascular shutdown following photodynamic therapy based on polyhaematoporphyrin of 5-aminolaevulinic acid. Int J Oncol 5: 763-768
27. Schoenfeld N, Epstein O, Lahav M, Mamet R, Shalai M and Atsmon A (1988) The heme biosynthetic pathway in lymphocytes of patients with malignant lymphoproliferative disorders. Cancer Lett 43: 43-48
28. Steinbach P, Weigandt H, Baumgartner R, Kreigmar M, Hofstadter F and Knuchel R (1995) Cellular fluorescence of the endogenous photosensitiser protoporphyrin IX following exposure to 5-aminolaevulinic acid. Photochem Photobiol 62: 887-895
29. Schick E, Kaufman R, Ruck A, Hainzl A and Boehncke WH (1995) Influence of activation and differentiation of cells on the effectiveness of photodynamic therapy. Acta Dermatol Venerol 75: 276-279
30. Stratford IJ and Stephens MA (1989) The differential hypoxic cytotoxicity of bioreductive agents determined in vitro by the MTT assay. Int J Radiat Oncol Biol Phys 16: 973-976
31. Van Steveninck J, Tijssen K, Boegheim JPJ, Van Der Zee J and Dubbleman TMAR (1986) Photodynamic generation of hydroxyl radicals by haematoporphyrin derivative and light. Photochem Photobiol 44: 711-716
32. Vaupel P, Kallinowski F and Okunieff P (1989) Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumours: a review. Cancer Res 49: 6449-6465
33. Weishaupt KR, Gomer CJ and Dougherty TJ (1976) Identification of singlet oxygen as the cytotoxic agent in photo-inactivation of a murine tumour. Cancer Res 36: 2326-2329
34. Yen A, Gigli I and Barrett KE (1990) Dual effects of protoporphyrin and long wave ultraviolet light on histamine release from rat peritoneal and cutaneous mast cells. J Immunol 144: 4327-4332