Current concepts of hyperinflammation in chronic granulomatous disease

Clinical and Developmental Immunology

Volumn 2012, Issue , 2012, Pages

  Hartl, Dominik ^a,b   Rieber, Nikolaus ^a,b   Hector, Andreas ^a,b   Kuijpers, Taco ^c,d   Roos, Dirk ^c  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c SANQUIN RESEARCH   (Netherlands)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANE PROTEIN; DIOXYGENASE; DIPHENYLIODONIUM SALT; GAMMA INTERFERON; INDOLAMINE 2,3 DIOXYGENASE; INFLAMMASOME; INTERLEUKIN 17; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; KYNURENINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

APOPTOSIS; CHRONIC GRANULOMATOUS DISEASE; GRANULOMATOUS INFLAMMATION; HUMAN; HYPERINFLAMMATION; INNATE IMMUNITY; LYMPHADENITIS; MACROPHAGE; NEUTROPHIL; NONHUMAN; OXIDATION; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE; TH17 CELL; ANIMAL; IMMUNOLOGY; INFLAMMATION; METABOLISM; MOUSE; PATHOPHYSIOLOGY;

ANIMALS; GRANULOMATOUS DISEASE, CHRONIC; HUMANS; INFLAMMATION; MICE;

EID: 80052715046     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2012/252460     Document Type: Review

References (50)

1. Dinauer M. C., Orkin S. H., Chronic granulomatous disease Annual Review of Medicine 1992 43 117 124
2. Roos D., The genetic basis of chronic granulomatous disease Immunological Reviews 1994 138 121 157 (Pubitemid 24147419)
3. Winkelstein J. A., Marino M. C., Johnston R. B. Jr., Boyle J., Curnutte J., Gallin J. I., Malech H. L., Holland S. M., Ochs H., Quie P., Buckley R. H., Foster C. B., Chanock S. J., Dickler H., Chronic granulomatous disease: report on a national registry of 368 patients Medicine 2000 79 3 155 169 (Pubitemid 30327530)
4. Malech H. L., Choi U., Brenner S., Progress toward effective gene therapy for chronic granulomatous disease Japanese Journal of Infectious Diseases 2004 57 5 S27 S28
5. Ott M. G., Schmidt M., Schwarzwaelder K., Stein S., Siler U., Koehl U., Glimm H., Khlcke K., Schilz A., Kunkel H., Naundorf S., Brinkmann A., Deichmann A., Fischer M., Ball C., Pilz I., Dunbar C., Du Y., Jenkins N. A., Copeland N. G., Lthi U., Hassan M., Thrasher A. J., Hoelzer D., Von Kalle C., Seger R., Grez M., Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1 Nature Medicine 2006 12 4 401 409
6. Stein S., Siler U., Ott M. G., Seger R., Grez M., Gene therapy for chronic granulomatous disease Current Opinion in Molecular Therapeutics 2006 8 415 422 (Pubitemid 44566782)
7. Kang E. M., Choi U., Theobald N., Linton G., Long Priel D. A., Kuhns D., Malech H. L., Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils Blood 2010 115 4 783 791
8. Aiuti A., Roncarolo M. G., Ten years of gene therapy for primary immune deficiencies Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2009 682 689
9. Pollock J. D., Williams D. A., Gifford M. A. C., Ling Lin Li, Du X., Fisherman J., Orkin S. H., Doerschuk C. M., Dinauer M. C., Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production Nature Genetics 1995 9 2 202 209
10. Kobayashi S. D., Voyich J. M., Braughton K. R., Whitney A. R., Nauseef W. M., Malech H. L., DeLeo F. R., Gene expression profiling provides insight into the pathophysiology of chronic granulomatous disease Journal of Immunology 2004 172 1 636 643 (Pubitemid 38020522)
11. Bylund J., MacDonald K. L., Brown K. L., Mydel P., Collins L. V., Hancock R. E. W., Speert D. P., Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS-independent activation of NF- B European Journal of Immunology 2007 37 4 1087 1096 (Pubitemid 46925344)
12. Henson P. M., Hume D. A., Apoptotic cell removal in development and tissue homeostasis Trends in Immunology 2006 27 5 244 250
13. Henson P. M., Dampening inflammation Nature Immunology 2005 6 12 1179 1181 (Pubitemid 43045625)
14. Sanford A. N., Suriano A. R., Herche D., Dietzmann K., Sullivan K. E., Abnormal apoptosis in chronic granulomatous disease and autoantibody production characteristic of lupus Rheumatology 2006 45 2 178 181 (Pubitemid 43160079)
15. Bernuth H. V., Kulka C., Roesler J., Gahr M., Rsen-Wolff A., NADPH oxidase is not required for spontaneous and Staphylococcus aureus-induced apoptosis of monocytes Annals of Hematology 2004 83 4 206 211 (Pubitemid 38443504)
16. Bylund J., Campsall P. A., Ma R. C., Conway B. A. D., Speert D. P., Burkholderia cenocepacia induces neutrophil necrosis in chronic granulomatous disease Journal of Immunology 2005 174 6 3562 3569 (Pubitemid 40354065)
17. Fernandez-Boyanapalli R. F., Frasch S. C., McPhillips K., Vandivier R. W., Harry B. L., Riches D. W. H., Henson P. M., Bratton D. L., Impaired apoptotic cell clearance in CGD due to altered macrophage programming is reversed by phosphatidylserine-dependent production of IL-4 Blood 2009 113 9 2047 2055
18. Fernandez-Boyanapalli R., McPhillips K. A., Frasch S. C., Janssen W. J., Dinauer M. C., Riches D. W. H., Henson P. M., Byrne A., Bratton D. L., Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN- in a nitric oxide-dependent manner Journal of Immunology 2010 185 7 4030 4041
19. Fernandez-Boyanapalli R., Frasch S. C., Riches D. W. H., Vandivier R. W., Henson P. M., Bratton D. L., PPAR activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease Blood 2010 116 22 4512 4522
20. Burg N. D., Pillinger M. H., The neutrophil: function and regulation in innate and humoral immunity Clinical Immunology 2001 99 1 7 17
21. Kobayashi S. D., Voyich J. M., Burlak C., DeLeo F. R., Neutrophils in the innate immune response Archivum Immunologiae et Therapiae Experimentalis 2005 53 6 505 517 (Pubitemid 43035779)
22. Nathan C., Neutrophils and immunity: challenges and opportunities Nature Reviews Immunology 2006 6 3 173 182 (Pubitemid 43290987)
23. Roos D., Winterbourn C. C., Immunology: lethal weapons Science 2002 296 5568 669 671 (Pubitemid 34441980)
24. Hartl D., Lehmann N., Hoffmann F., Jansson A., Hector A., Notheis G., Roos D., Belohradsky B. H., Wintergerst U., Dysregulation of innate immune receptors on neutrophils in chronic granulomatous disease Journal of Allergy and Clinical Immunology 2008 121 2, article e9 375 382
25. Gaither T. A., Gallin J. I., Iida K., Nussenzweig V., Frank M. M., Deficiency in C3b receptors on neutrophils of patients with chronic granulomatous disease and hyperimmunoglobulin-E recurrent infection (Job's) syndrome Inflammation 1984 8 4 429 444 (Pubitemid 15176936)
26. Olofsson P., Holmberg J., Tordsson J., Lu S., kerstrm B., Holmdahl R., Positional identification of Ncf1 as a gene that regulates arthritis severity in rats Nature Genetics 2003 33 1 25 32 (Pubitemid 36068678)
27. Huang C. K., Zhan L., Hannigan M. O., Ai Y., Leto T. L., P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+ Journal of Leukocyte Biology 2000 67 2 210 215
28. Gelderman K. A., Hultqvist M., Holmberg J., Olofsson P., Holmdahl R., T cell surface redox levels determine T cell reactivity and arthritis susceptibility Proceedings of the National Academy of Sciences of the United States of America 2006 103 34 12831 12836 (Pubitemid 44298647)
29. Pizzolla A., Gelderman K. A., Hultqvist M., CD68-expressing cells can prime T cells and initiate autoimmune arthritis in the absence of reactive oxygen species European Journal of Immunology 2011 41 403 412
30. Bettelli E., Oukka M., Kuchroo V. K., TH-17 cells in the circle of immunity and autoimmunity Nature Immunology 2007 8 4 345 350 (Pubitemid 46745409)
31. Annunziato F., Cosmi L., Santarlasci V., Maggi L., Liotta F., Mazzinghi B., Parente E., Fil L., Ferri S., Frosali F., Giudici F., Romagnani P., Parronchi P., Tonelli F., Maggi E., Romagnani S., Phenotypic and functional features of human Th17 cells Journal of Experimental Medicine 2007 204 8 1849 1861 (Pubitemid 47240944)
32. Sakaguchi S., Yamaguchi T., Nomura T., Ono M., Regulatory T cells and immune tolerance Cell 2008 133 5 775 787 (Pubitemid 351707693)
33. Bettelli E., Carrier Y., Gao W., Korn T., Strom T. B., Oukka M., Weiner H. L., Kuchroo V. K., Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells Nature 2006 441 7090 235 238
34. Stevens E. A., Bradfield C. A., Immunology: T cells hang in the balance Nature 2008 453 7191 46 47 (Pubitemid 351630318)
35. Romani L., Fallarino F., De Luca A., Montagnoli C., D'Angelo C., Zelante T., Vacca C., Bistoni F., Fioretti M. C., Grohmann U., Segal B. H., Puccetti P., Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease Nature 2008 451 7175 211 215
36. Segal B. H., Han W., Bushey J. J., NADPH oxidase limits innate immune responses in the lungs in mice PLoS One 2010 5, article e9631
37. Opitz C. A., Wick W., Steinman L., Platten M., Tryptophan degradation in autoimmune diseases Cellular and Molecular Life Sciences 2007 64 19-20 2542 2563 (Pubitemid 350035605)
38. Platten M., Ho P. P., Youssef S., Fontoura P., Garren H., Hur E. M., Gupta R., Lee L. Y., Kidd B. A., Robinson W. H., Sobel R. A., Selley M. L., Steinman L., Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite Science 2005 310 5749 850 855 (Pubitemid 41567343)
39. Veldhoen M., Hirota K., Westendorf A. M., Buer J., Dumoutier L., Renauld J. C., Stockinger B., The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins Nature 2008 453 7191 106 109 (Pubitemid 351630329)
40. Mellor A. L., Munn D. H., IDO expression by dendritic cells: tolerance and tryptophan catabolism Nature Reviews Immunology 2004 4 10 762 774 (Pubitemid 39336293)
41. Munn D. H., Zhou M., Attwood J. T., Bondarev I., Conway S. J., Marshall B., Brown C., Mellor A. L., Prevention of allogeneic fetal rejection by tryptophan catabolism Science 1998 281 5380 1191 1193 (Pubitemid 28406294)
42. Sharma M. D., Baban B., Chandler P., Hou D. Y., Singh N., Yagita H., Azuma M., Blazar B. R., Mellor A. L., Munn D. H., Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase Journal of Clinical Investigation 2007 117 9 2570 2582 (Pubitemid 47494358)
43. Comi G., Pulizzi A., Rovaris M., Abramsky O., Arbizu T., Boiko A., Gold R., Havrdova E., Komoly S., Selmaj K., Sharrack B., Filippi M., Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study The Lancet 2008 371 9630 2085 2092 (Pubitemid 351842581)
44. Macchiarulo A., Nuti R., Bellocchi D., Camaioni E., Pellicciari R., Molecular docking and spatial coarse graining simulations as tools to investigate substrate recognition, enhancer binding and conformational transitions in indoleamine-2,3-dioxygenase (IDO) Biochimica et Biophysica Acta 2007 1774 8 1058 1068 (Pubitemid 47176959)
45. De Ravin S. S., Zarember K. A., Long-Priel D., Chan K. C., Fox S. D., Gallin J. I., Kuhns D. B., Malech H. L., Tryptophan/kynurenine metabolism in human leukocytes is independent of superoxide and is fully maintained in chronic granulomatous disease Blood 2010 116 10 1755 1760
46. Jrgens B., Fuchs D., Reichenbach J., Heitger A., Intact indoleamine 2,3-dioxygenase activity in human chronic granulomatous disease Clinical Immunology 2010 137 1 1 4
47. Tschopp J., Schroder K., NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? Nature Reviews Immunology 2010 10 3 210 215
48. Van De Veerdonk F. L., Smeekens S. P., Joosten L. A. B., Kullberg B. J., Dinarello C. A., Van Der Meer J. W. M., Netea M. G., Reactive oxygen species-independent activation of the IL-1 inflammasome in cells from patients with chronic granulomatous disease Proceedings of the National Academy of Sciences of the United States of America 2010 107 7 3030 3033
49. Meissner F., Seger R. A., Moshous D., Fischer A., Reichenbach J., Zychlinsky A., Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease Blood 2010 116 9 1570 1573
50. Van Bruggen R., Kker M. Y., Jansen M., Van Houdt M., Roos D., Kuijpers T. W., Van Den Berg T. K., Human NLRP3 inflammasome activation is Nox1-4 independent Blood 2010 115 26 5398 5400