Dysregulation of innate immune receptors on neutrophils in chronic granulomatous disease

Journal of Allergy and Clinical Immunology

Volumn 121, Issue 2, 2008, Pages

  Hartl, Dominik ^a   Lehmann, Natalie ^a   Hoffmann, Florian ^a   Jansson, Annette ^a   Hector, Andreas ^a   Notheis, Gundula ^a   Roos, Dirk ^b   Belohradsky, Bernd H ^a   Wintergerst, Uwe ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Chronic granulomatous disease; complement receptors; CXCR1; innate immune system; neutrophils; nicotinamide adenine dinucleotide phosphate oxidase; Toll like receptor 5; Toll like receptor 9; Toll like receptors

Indexed keywords

CD11B ANTIGEN; CD18 ANTIGEN; CHEMOKINE RECEPTOR CXCR1; COMPLEMENT COMPONENT C3B RECEPTOR; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 9;

ADOLESCENT; ADULT; ARTICLE; BACTERIAL PNEUMONIA; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GRANULOMATOSIS; HUMAN; INNATE IMMUNITY; LEUKOCYTE ACTIVATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STAPHYLOCOCCUS AUREUS;

EID: 39149108430     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2007.10.037     Document Type: Article

References (37)

1. Dinauer M.C., and Orkin S.H. Chronic granulomatous disease. Annu Rev Med 43 (1992) 117-124
2. Roos D. The genetic basis of chronic granulomatous disease. Immunol Rev 138 (1994) 121-157
3. Johnston Jr. R.B. Clinical aspects of chronic granulomatous disease. Curr Opin Hematol 8 (2001) 17-22
4. Malech H.L., Choi U., and Brenner S. Progress toward effective gene therapy for chronic granulomatous disease. Jpn J Infect Dis 57 suppl (2004) S27-S28
5. Ott M.G., Schmidt M., Schwarzwaelder K., Stein S., Siler U., Koehl U., et al. Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1. Nat Med 12 (2006) 401-409
6. Stein S., Siler U., Ott M.G., Seger R., and Grez M. Gene therapy for chronic granulomatous disease. Curr Opin Mol Ther 8 (2006) 415-422
7. Roos D., and Winterbourn C.C. Immunology-lethal weapons. Science 296 (2002) 669-671
8. Lehrer R.I., Ganz T., Selsted M.E., Babior B.M., and Curnutte J.T. Neutrophils and host defense. Ann Intern Med 109 (1988) 127-142
9. Roos D., van Bruggen R., and Meischl C. Oxidative killing of microbes by neutrophils. Microbes Infect 5 (2003) 1307-1315
10. Burg N.D., and Pillinger M.H. The neutrophil: function and regulation in innate and humoral immunity. Clin Immunol 99 (2001) 7-17
11. Kobayashi S.D., Voyich J.M., Burlak C., and DeLeo F.R. Neutrophils in the innate immune response. Arch Immunol Ther Exp (Warsz) 53 (2005) 505-517
12. Baggiolini M., Dewald B., and Moser B. Interleukin-8 and related chemotactic cytokines-Cxc and Cc chemokines. Adv Immunol 55 (1994) 97-179
13. Akira S., and Takeda K. Toll-like receptor signalling. Nat Rev Immunol 4 (2004) 499-511
14. Cook J., and Kazatchkine M. The human C3b receptor. Nouv Rev Fr Hematol 25 (1983) 297-301
15. Sengelov H. Complement receptors in neutrophils. Crit Rev Immunol 15 (1995) 107-131
16. Stossel T.P. Phagocytosis. Prog Clin Biol Res 13 (1977) 87-102
17. Fallman M., Andersson R., and Andersson T. Signaling properties of CR3 (CD11b/CD18) and CR1 (CD35) in relation to phagocytosis of complement-opsonized particles. J Immunol 151 (1993) 330-338
18. Bylund J., Macdonald K.L., Brown K.L., Mydel P., Collins L.V., Hancock R.E., et al. Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS-independent activation of NF-kappa B. Eur J Immunol 37 (2007) 1087-1096
19. Lekstrom-Himes J.A., Kuhns D.B., Alvord W.G., and Gallin J.I. Inhibition of human neutrophil IL-8 production by hydrogen peroxide and dysregulation in chronic granulomatous disease. J Immunol 174 (2005) 411-417
20. Kobayashi S.D., Voyich J.M., Braughton K.R., Whitney A.R., Nauseef W.M., Malech H.L., et al. Gene expression profiling provides insight into the pathophysiology of chronic granulomatous disease. J Immunol 172 (2004) 636-643
21. De Gendt C.M., De Clerck L.S., Bridts C.H., and Stevens W.J. The use of calcein acetomethylester (AM)-labelled polymorphonuclear cells in a polycarbonate filter chemotaxis assay. Clin Chim Acta 249 (1996) 189-195
22. Motulsky H. Intuitive biostatistics (1995), Oxford University Press, New York
23. Berger M., O'Shea J., Cross A.S., Folks T.M., Chused T.M., Brown E.J., et al. Human neutrophils increase expression of C3bi as well as C3b receptors upon activation. J Clin Invest 74 (1984) 1566-1571
24. Quie P.G. Phagocytic cell dysfunction. J Allergy Clin Immunol 77 (1986) 387-398
25. Hayashi F., Means T.K., and Luster A.D. Toll-like receptors stimulate human neutrophil function. Blood 102 (2003) 2660-2669
26. Hayashi F., Smith K.D., Ozinsky A., Hawn T.R., Yi E.C., Goodlett D.R., et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 410 (2001) 1099-1103
27. Prince A. Flagellar activation of epithelial signaling. Am J Respir Cell Mol Biol 34 (2006) 548-551
28. Akira S. TLR signaling. Curr Top Microbiol Immunol 311 (2006) 1-16
29. Alvarez M.E., Bass J.I., Geffner J.R., Calotti P.X., Costas M., Coso O.A., et al. Neutrophil signaling pathways activated by bacterial DNA stimulation. J Immunol 177 (2006) 4037-4046
30. Jozsef L., Khreiss T., and Filep J.G. CpG motifs in bacterial DNA delay apoptosis of neutrophil granulocytes. FASEB J 18 (2004) 1776-1778
31. Jozsef L., Khreiss T., El Kebir D., and Filep J.G. Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils. J Immunol 176 (2006) 1195-1202
32. Gaither T.A., Gallin J.I., Iida K., Nussenzweig V., and Frank M.M. Deficiency in C3b receptors on neutrophils of patients with chronic granulomatous disease and hyperimmunoglobulin-E recurrent infection (Job's) syndrome. Inflammation 8 (1984) 429-444
33. Grumach A.S., Bellinai-Pires R., Araujo I.S., Gonzalez C.H., and Carneiro-Sampaio M.M. Chronic granulomatous disease of childhood: differential diagnosis and prognosis. Rev Paul Med 111 (1993) 472-476
34. Assari T. Chronic granulomatous disease; fundamental stages in our understanding of CGD. Med Immunol 5 (2006) 4
35. Hasui M., Hirabayashi Y., Hattori K., and Kobayashi Y. Increased phagocytic activity of polymorphonuclear leukocytes of chronic granulomatous disease as determined with flow cytometric assay. J Lab Clin Med 117 (1991) 291-298
36. Albelda S.M., Smith C.W., and Ward P.A. Adhesion molecules and inflammatory injury. FASEB J 8 (1994) 504-512
37. Winkelstein J.A., Marino M.C., Johnston Jr. R.B., Boyle J., Curnutte J., Gallin J.I., et al. Chronic granulomatous disease. Report on a national registry of 368 patients. Medicine (Baltimore) 79 (2000) 155-169