Stem cell-based therapy and regenerative approaches to diseases of the respiratory system

British Medical Bulletin

Volumn 99, Issue 1, 2011, Pages 169-187

  Jungebluth, Philipp ^a   MacChiarini, Paolo ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Regenerative medicine; Respiratory diseases; SC based therapy; Tissue engineering

Indexed keywords

ACUTE LUNG INJURY; ARTICLE; ASTHMA; CELL DIFFERENTIATION; CELL GROWTH; CELL STIMULATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CYSTIC FIBROSIS; EPIGENETICS; GENE CONTROL; HUMAN; IMMUNOMODULATION; LARYNX DISORDER; LUNG CANCER; LUNG FIBROSIS; META ANALYSIS; NONHUMAN; PHARYNGITIS; PRIORITY JOURNAL; PULMONARY HYPERTENSION; REGENERATIVE MEDICINE; RESPIRATORY TRACT DISEASE; RHINITIS; STEM CELL TRANSPLANTATION; SYSTEMATIC REVIEW; TISSUE ENGINEERING; TRACHEA DISEASE;

CELL PHYSIOLOGICAL PROCESSES; CLINICAL TRIALS AS TOPIC; GENETIC THERAPY; HUMANS; REGENERATION; REGENERATIVE MEDICINE; RESPIRATORY PHYSIOLOGICAL PHENOMENA; RESPIRATORY SYSTEM; RESPIRATORY TRACT DISEASES; STEM CELL RESEARCH; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING;

EID: 80052699988     PISSN: 00071420     EISSN: 14718391     Source Type: Journal    
DOI: 10.1093/bmb/ldr028     Document Type: Article

References (54)

1. Mason C, Dunnill P. A brief definition of regenerative medicine. Regen Med 2008;3:1-5. (Pubitemid 351541190)
2. Korbling M, Estrov Z. Adult stem cells for tissue repair-a new therapeutic concept?. N Engl J Med 2003;349:570-82. (Pubitemid 36951370)
3. Lister R, Pelizzola M, Kida YS et al. Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature 2011;471:68-73.
4. Mailleux AA, Kelly R, Veltmaat JM et al. Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage. Development 2005;132:2157-66. (Pubitemid 40744475)
5. Kim CF, Jackson EL, Woolfenden AE et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 2005;121:823-35. (Pubitemid 40806415)
6. Reya T, Morrison SJ, Clarke MF et al. Stem cells, cancer, and cancer stem cells. Nature 2001;414:105-11. (Pubitemid 33041634)
7. Gomperts BN, Belperio JA, Rao PN et al. Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injury. J Immunol 2006;176:1916-27. (Pubitemid 43134337)
8. Suzuki T, Kobayashi K, Tada Y et al. Regeneration of the trachea using a bioengineered scaffold with adipose-derived stem cells. Ann Otol Rhinol Laryngol 2008;117:453-63.
9. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-76. (Pubitemid 44233629)
10. Goren A, Dahan N, Goren E et al. Encapsulated human mesenchymal stem cells: a unique hypoimmunogenic platform for long-term cellular therapy. FASEB J 2010;24:22-31.
11. Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 1997;276:71-4. (Pubitemid 27161245)
12. Nauta AJ, Westerhuis G, Kruisselbrink AB et al. Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting. Blood 2006;108:2114-20. (Pubitemid 44395028)
13. Furlani D, Li W, Pittermann E et al. A transformed cell population derived from cultured mesenchymal stem cells has no functional effect after transplantation into the injured heart. Cell Transplant 2009;18:319-31.
14. Jungebluth P, Luedde M, Ferrer E et al. Mesenchymal stem cells restore lung function by recruiting resident and non-resident proteins. Cell Transplant 2011 [Epub ahead of print].
15. Perasso L, Cogo CE, Giunti D et al. Systemic administration of mesenchymal stem cells increases neuron survival after global cerebral ischemia in vivo (2VO). Neural Plast 2010;2010:534925.
16. Zhao Q, Liu Z, Wang Z et al. Effect of prepro-calcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension. Ann Thorac Surg 2007;84:544-52. (Pubitemid 47069188)
17. Kanki-Horimoto S, Horimoto H, Mieno S et al. Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improves right ventricular impairments caused by pulmonary hypertension. Circulation 2006;114:I181-5. (Pubitemid 44297148)
18. Nagaya N, Kangawa K, Kanda M et al. Hybrid cell-gene therapy for pulmonary hypertension based on phagocytosing action of endothelial progenitor cells. Circulation 2003;108:889-95. (Pubitemid 37022134)
19. Takemiya K, Kai H, Yasukawa H et al. Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats. Basic Res Cardiol 2010;105:409-17.
20. Bader A, Macchiarini P. Moving towards in situ tracheal regeneration: the bionic tissue engineered transplantation approach. J Cell Mol Med 2010;14:1877-89.
21. Goodwin M, Eisenhauer PL, Sueblinvong V et al. Systemic administration of mesenchymal stem cells abrogates allergic airways inflammation by inhibiting CD4 T cell Th2 phenotype development. Am J Respir Crit Care Med 2009;179:A3681.
22. Nemeth K, Keane-Myers A, Brown JM et al. Bone marrow stromal cells use TGF-beta to suppress allergic responses in a mouse model of ragweed-induced asthma. Proc Natl Acad Sci USA 2010;107:5652-7.
23. Lendlein A, Behl M, Hiebl B et al. Shape-memory polymers as a technology platform for biomedical applications. Expert Rev Med Devices 2010;7:357-79.
24. Zhang L, Cheng JP, Zhang WC et al. Reconstruction of defects following surgery for hypopharyngeal carcinoma using artificial biological material. Acta Otolaryngol 2010;130:1293-9.
25. Baiguera S, Gonfiotti A, Jaus M et al. Development of bioengineered human larynx. Biomaterials 2011;32:4433-42.
26. Grillo HC. Tracheal replacement: a critical review. Ann Thorac Surg 2002;73:1995-2004. (Pubitemid 34596770)
27. Macchiarini P, Jungebluth P, Go T et al. Clinical transplantation of a tissue-engineered airway. Lancet 2008;372:2023-30.
28. Adachi Y, Oyaizu H, Taketani S et al. Treatment and transfer of emphysema by a new bone marrow transplantation method from normal mice to Tsk mice and vice versa. Stem Cells 2006;24:2071-7. (Pubitemid 44477132)
29. Zhen G, Liu H, Gu N et al. Mesenchymal stem cells transplantation protects against rat pulmonary emphysema. Front Biosci 2008;13:3415-22. (Pubitemid 351594692)
30. van Haaften T, Byrne R, Bonnet S et al. Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med 2009;180:1131-42.
31. Xu J, Woods CR, Mora AL, et al. Prevention of endotoxin-induced systemic response by bone marrow-derived mesenchymal stem cells in mice. Am J Physiol Lung Cell Mol Physiol 2007;293:L131-41. (Pubitemid 47080721)
32. Gupta N, Su X, Popov B et al. Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol 2007;179:1855-63.
33. Ortiz LA, Gambelli F, McBride C et al. Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects. Proc Natl Acad Sci USA 2003;100:8407-11. (Pubitemid 36842558)
34. Aguilar S, Scotton CJ, McNulty K et al. Bone marrow stem cells expressing keratinocyte growth factor via an inducible lentivirus protects against bleomycin-induced pulmonary fibrosis. PLoS One 2009;4:e8013.
35. Rojas M, Xu J, Woods CR et al. Bone marrow-derived mesenchymal stem cells in repair of the injured lung. Am J Respir Cell Mol Biol 2005;33:145-52. (Pubitemid 41473051)
36. Xu J, Qu J, Cao L et al. Mesenchymal stem cell-based angiopoietin-1 gene therapy for acute lung injury induced by lipopolysaccharide in mice. J Pathol 2008;214:472-81. (Pubitemid 351340567)
37. Nemeth K, Leelahavanichkul A, Yuen PS et al. Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production. Nat Med 2009;15:42-9.
38. Lee JW, Fang X, Gupta N et al. Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung. Proc Natl Acad Sci USA 2009;106:16357-62.
39. Fang X, Neyrinck AP, Matthay MA et al. Allogeneic human mesenchymal stem cells restore epithelial protein permeability in cultured human alveolar type II cells by secretion of angiopoietin-1. J Biol Chem 2010;285:26211-22.
40. Mehrad B, Burdick MD, Zisman DA et al. Circulating peripheral blood fibrocytes in human fibrotic interstitial lung disease. Biochem Biophys Res Commun 2007;353:104-8. (Pubitemid 44958347)
41. Bruscia EM, Price JE, Cheng EC et al. Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation. Proc Natl Acad Sci USA 2006;103:2965-70.
42. Sueblinvong V, Loi R, Eisenhauer PL et al. Derivation of lung epithelium from human cord blood-derived mesenchymal stem cells. Am J Respir Crit Care Med 2008;177:701-11. (Pubitemid 351490557)
43. Baber SR, Deng W, Master RG et al. Intratracheal mesenchymal stem cell administration attenuates monocrotaline-induced pulmonary hypertension and endothelial dysfunction. Am J Physiol Heart Circ Physiol 2007;292:H1120-8.
44. Takahashi M, Nakamura T, Toba T et al. Transplantation of endothelial progenitor cells into the lung to alleviate pulmonary hypertension in dogs. Tissue Eng 2004;10:771-9. (Pubitemid 38880395)
45. Young KC, Torres E, Hatzistergos KE et al. Inhibition of the SDF-1/CXCR4 axis attenuates neonatal hypoxia-induced pulmonary hypertension. Circ Res 2009;104:1293-301.
46. Frid MG, Brunetti JA, Burke DL et al. Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage. Am J Pathol 2006;168:659-69. (Pubitemid 43271163)
47. Quante M, Tu SP, Tomita H et al. Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth. Cancer Cell 2011;19:257-72.
48. Klopp AH, Gupta A, Spaeth E. et al. Concise review: dissecting a discrepancy in the literature: do mesenchymal stem cells support or suppress tumor growth?. Stem Cells 2011;29:11-9.
49. Shih CC, Forman SJ, Chu P et al. Human embryonic stem cells are prone to generate primitive, undifferentiated tumors in engrafted human fetal tissues in severe combined immunodeficient mice. Stem Cells Dev 2007;16:893-902.
50. Ott HC, Clippinger B, Conrad C et al. Regeneration and orthotopic transplantation of a bioartificial lung. Nat Med 2010;16:927-33.
51. Petersen TH, Calle EA, Zhao L et al. Tissue-engineered lungs for in vivo implantation. Science 2010;329:538-41.
52. Huh D, Matthews BD, Mammoto A et al. Reconstituting organ-level lung functions on a chip. Science 2010;328:1662-8.
53. Kahler CM, Wechselberger J, Hilbe W et al. Peripheral infusion of rat bone marrow derived endothelial progenitor cells leads to homing in acute lung injury. Respir Res 2007;8:50.
54. Leblond AL, Naud P, Forest V et al. Developing cell therapy techniques for respiratory disease: intratracheal delivery of genetically engineered stem cells in a murine model of airway injury. Hum Gene Ther 2009;20:1329-43.